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Electrokinetic Particle Manipulations In Spiral Microchannels, John Dubose
Electrokinetic Particle Manipulations In Spiral Microchannels, John Dubose
All Theses
Recent developments in the field of microfluidics have created a multitude of new useful techniques for practical particle and cellular assays. Among them is the use of dielectrophoretic forces in 'lab-on-a-chip' devices. This sub-domain of electrokinetic flow is particularly popular due to its advantages in simplicity and versatility. This thesis makes use of dielectrophoretic particle manipulations in three distinct spiral microchannels. In the first of these experiments, we demonstrate the utility of a novel single-spiral curved microchannel with a single inlet reservoir and a single outlet reservoir for the continuous focusing and filtration of particles. The insulator-based negative-dielectrophoretic (repulsive) force …
Magnetic Manipulation Of Particles And Cells In Ferrofluid Flow Through Straight Microchannels Using Two Magnets, Jian Zeng
All Theses
Microfluidic devices have been increasingly used in the past two decades for particle and cell manipulations in many chemical and biomedical applications. A variety of force fields have been demonstrated to control particle and cell transport in these devices including electric, magnetic, acoustic, and optical forces etc. Among these particle handling techniques, the magnetic approach provides clear advantages over others such as low cost, noninvasive, and free of fluid heating issues. However, the current knowledge of magnetic control of particle transport is still very limited, especially lacking is the handling of diamagnetic particle. This thesis is focused on the magnetic …