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Mechanical Engineering

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Missouri University of Science and Technology

2010

Biocompatibility<br />Biomedical materials<br />Hydroxyapatite<br />Microspheres

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Synthesis And Characterization Of Microspheres For Controlled Release, Gurpartap Singh Sandhu Jan 2010

Synthesis And Characterization Of Microspheres For Controlled Release, Gurpartap Singh Sandhu

Masters Theses

"Synthetic hydroxyapatite (HAp, (Ca₁₀(PO₄)₆(OH)₂) has always been of interest in medical applications because of its similarities to inorganic bone matrix. It has been used in biomedical applications for bone repair and substitution due to its biocompatibility. However, there are some differences in the stoichiometry, composition, and mechanical properties of human bone as compared to pure HAP. HAp particles have been successfully used as drug delivery carriers which deliver the drug to the affected part of the body and the remaining apatite gets degraded by the physiological processes in the body. In the present work, emphasis was on developing mechanically stronger …