Engineering Commons^™

Detection Of Nucleotides In Hydrated Ssdna Via 2-D H-Bn Nanopore With Ionic-Liquid/Salt-Water Interface, Jungsoo Lee

Multidisciplinary Studies Theses and Dissertations

Accomplishing slow translocation speed with high sensitivity has been the greatest mission for solid-state nanopore (SSN) to electrically detect nucleobases in single-stranded DNA (ssDNA). In this study, a method to detect nucleobases in ssDNA using a SSN is introduced by considerably slowing down the translocation speed and effectively increasing its sensitivity. The ultra-thin titanium dioxide (TiO₂) coated hexagonal boron nitride (h-BN) nanopore was fabricated, along with an ionic-liquid [bmim][PF₆]/2.0 M KCl aqueous (cis/trans) interfacial system, to increase both the spatial and the temporal resolutions. As the ssDNA molecules entered the nanopore, a …

Homogenization Of Composite And Cellular Materials Incorporating Microstructure And Surface Energy Effects, Ahmad Gad

Mechanical Engineering Research Theses and Dissertations

In the last few decades, the popularity of composite and cellular materials has rapidly increased through their widespread applications in multiple engineering fields including aerospace, automotive, civil and biomedical. However, to a large extent, the success of their practical applications depends on our ability to predict their mechanical behavior by using high-fidelity mechanics models.

Micromechanical modeling of composite and cellular materials is a challenging task due to the heterogeneous nature of such materials and the interactions among various constituent phases at the microscopic level, which result in non-homogeneous deformation, strain and stress fields. Therefore, it is necessary to develop simple …