Engineering Commons^™

Magnetic Shape Memory Micro-Pump For Intra-Cranial Drug Delivery, Sam Barker, Eric Rhoads, Andrew Morrison, Miranda Buttram, Paul Lindquist

College of Engineering Presentations

Magnetic shape-memory alloys exhibit strong magneto-structural coupling enabling large magnetic-field-induced deformation. Local control of twinning via variable inhomogeneous magnetic fields initiates local reversible deformation. Previous work produced a valve-less micropump consisting of a Ni-Mn-Ga single crystal, a casing, and a rod magnet. The micropump successfully pumped fluid in opposite directions when the magnet was turned clockwise and counter clockwise. Our current work modifies this micropump for application in rat a head stage, which would simultaneously monitor electroencephalograph data and deliver 0.5-5.0 μl of a drug solution at 100-500 nl/min directly to the rat’s brain. These improvements and the application of …