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Full-Text Articles in Engineering

Evaluating Satellite Products For Precipitation Estimation In Mountain Regions: A Case Study For Nepal, Nir Y. Krakauer, Soni M. Pradhanang, Tarendra Lakhankar, Ajay K. Jha Aug 2013

Evaluating Satellite Products For Precipitation Estimation In Mountain Regions: A Case Study For Nepal, Nir Y. Krakauer, Soni M. Pradhanang, Tarendra Lakhankar, Ajay K. Jha

Publications and Research

Precipitation in mountain regions is often highly variable and poorly observed, limiting abilities to manage water resource challenges. Here, we evaluate remote sensing and ground station-based gridded precipitation products over Nepal against weather station precipitation observations on a monthly timescale. We find that the Tropical Rainfall Measuring Mission (TRMM) 3B-43 precipitation product exhibits little mean bias and reasonable skill in giving precipitation over Nepal. Compared to station observations, the TRMM precipitation product showed an overall Nash-Sutcliffe efficiency of 0.49, which is similar to the skill of the gridded station-based product Asian Precipitation-Highly Resolved Observational Data Integration Towards Evaluation of Water …


Synthesis Of 4-Azidocoumarins And Their Use In Copper-Catalyzed Azide-Alkyne Cycloaddition Reactions, Anthony J. Netsuri Jan 2013

Synthesis Of 4-Azidocoumarins And Their Use In Copper-Catalyzed Azide-Alkyne Cycloaddition Reactions, Anthony J. Netsuri

Dissertations and Theses

Triazole-containing compounds have shown great biological activity ranging from antiviral, antibacterial, to anticancer, to name a few. Coumarin derivatives have also shown interesting biological activities. The combination of these bioactive compounds appears to have great promise for new and future medicines. In this work, various 4-azido-coumarins were synthesized via the transformation of the 4-hydroxy derivatives to 4-benzotriazolyloxy coumarins by reaction with the peptide coupling agent (benzotriazol-1-yloxy)tris-(dimethylamino)phosphonium hexafluorophosphate (BOP), and 1,8-diazabicycloundec-7-ene (DBU) as the base, in tetrahydrofuran (THF) solvent. The 4-benzotriazolyloxy coumarins were converted to the 4-azidocoumarins by reaction with sodium azide (NaN3), and the overall process was simplified to a …