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2005

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Full-Text Articles in Engineering

Distribution Pattern Variability Of Granular Vrt Applicators, John P. Fulton, Scott A. Shearer, Stephen F. Higgins, Dennis Wayne Hancock, Timothy S. Stombaugh Nov 2005

Distribution Pattern Variability Of Granular Vrt Applicators, John P. Fulton, Scott A. Shearer, Stephen F. Higgins, Dennis Wayne Hancock, Timothy S. Stombaugh

Biosystems and Agricultural Engineering Faculty Publications

Granular applicators equipped with variable-rate technology (VRT) have gained popularity in recent years as a result of increased interest in variable-rate application. The purpose of this investigation was to characterize distribution patterns at varying rates for different granular applicators. Uniform-rate (UR) tests were conducted to assess the accuracy of variable-rate application from four granular applicators: two spinner-disc spreaders (A and B), and two pneumatic applicators (C and D). Pattern results indicated a consistent triangular pattern for spinner spreader B and consistent patterns for the pneumatic applicators (C and D). However, applicator D produced pattern variations at the center and right …


Rate Response Assessment From Various Granular Vrt Applicators, John P. Fulton, Scott A. Shearer, Stephen F. Higgins, Matthew J. Darr, Timothy S. Stombaugh Nov 2005

Rate Response Assessment From Various Granular Vrt Applicators, John P. Fulton, Scott A. Shearer, Stephen F. Higgins, Matthew J. Darr, Timothy S. Stombaugh

Biosystems and Agricultural Engineering Faculty Publications

Variable-rate technology (VRT) adds complexity to application equipment, thereby confounding the assessment of applicator performance. The intent of this investigation was to assess the rate response of various VRT granular applicators: two spinner spreaders (A and B), and two pneumatic applicators (C and D). Variable-rate (VR) tests were conducted to quantify the rate response characteristics (delay and transition times) for the applicators. A sigmoidal function was used to model the rate response for five of the six tests. Applicator A exhibited a linear response during decreasing rate changes. Results indicated that only applicator B demonstrated consistent delay and transition times, …


2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library Oct 2005

2005 Scholars And Artists Bibliography, Stephen D. Slane Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr, Steve Slane was the guest speaker.


Structure Of Human Thymidylate Synthase Under Low-Salt Conditions, Leslie L. Lovelace, Wladek Minor, Lukasz Lebioda Sep 2005

Structure Of Human Thymidylate Synthase Under Low-Salt Conditions, Leslie L. Lovelace, Wladek Minor, Lukasz Lebioda

Faculty Publications

Human thymidylate synthase, a target in cancer chemotherapy, was crystallized from PEG 3350 with 30 mM ammonium sulfate (AS) in the crystallization medium. The crystals are isomorphous with the high-salt crystals (~2.0 M AS) and the structure has been solved and refined (R = 22.6%, Rfree = 24.3%) at 1.8 Å resolution. The high- and low-AS-concentration structures are quite similar, with loop 181-197 is in the inactive conformation. Also, residues 95-106 and 129-135 (eukaryotic inserts region) show high mobility as assessed by poor electron density and high values of crystallographic temperature factors (residues 1-25 and 108-129 are disordered in both …


Sheep Updates 2005 - Part 2, Peter Tozer, Janette Drew, K. E. Kemper, M. L. Hebart, F. D. Brien, K. S. Jaensch, R. J. Grimson, D. H. Smith, A. M. M. Ramsay, J. S. Richards, K. D. Atkins, T. Thompson, W. K. Murray, J. R. L. Hall, Chris Carter, Peter Tozer, Mark Hyder, John Young, B. A. Mcgregor, Patricia Harper Jul 2005

Sheep Updates 2005 - Part 2, Peter Tozer, Janette Drew, K. E. Kemper, M. L. Hebart, F. D. Brien, K. S. Jaensch, R. J. Grimson, D. H. Smith, A. M. M. Ramsay, J. S. Richards, K. D. Atkins, T. Thompson, W. K. Murray, J. R. L. Hall, Chris Carter, Peter Tozer, Mark Hyder, John Young, B. A. Mcgregor, Patricia Harper

Sheep Updates

This session covers seven papers from different authors: CONCURRENT SESSIONS - STRATEGIC MANAGEMENT 1.Finishing Pastoral Lambs, Peter Tozer, Patricia Harper, Janette Drew, Department of Agriculture Western Australia 2. Coating Improves Wool Quality under Mixed Farming Conditions, KE Kemper, ML Hebart, FD Brien, KS Grimson, DH Smith AMM Ramsay, South Australian Research and Development Institute 3. J. S. Richards, K.D. Atkins, T. Thompson, W. K. Murray, Australian Sheep Industry Co-operative Research Centre and NSW Department of Primary Industries, Orange Agricultural Institute, Forest Rd. Orange 4. Strategic Risk Management in the Sheep Industry, J.R.L. Hall, ICON Agriculture (JRL Hall & Co) 5. …


Spatial Variation Of Protein, Oil, And Starch In Corn, Samuel G. Mcneill, Michael D. Montross, Scott A. Shearer Jul 2005

Spatial Variation Of Protein, Oil, And Starch In Corn, Samuel G. Mcneill, Michael D. Montross, Scott A. Shearer

Biosystems and Agricultural Engineering Faculty Publications

Significant spatial yield variations are known to exist in cornfields with different soil types, topsoil depth, and other variables. Similarly, variations might also be found among the highly valued chemical components (oil, protein, and starch) in corn kernels due to local differences in soil type, fertility, acidity/pH, organic matter, etc. This study quantified the spatial variability of protein, oil, and starch content of corn from two conventional cornfields and two high-oil cornfields. Whole ears were harvested by hand from 20 to 40 randomly selected locations within each field. A differential global positioning system (DGPS) receiver recorded the location of each …


Dynamic Matrix Composition In Engineered Cartilage With Stochastic Supplementation Of Growth Factors, Asit K. Saha, J. (Jagannath) Mazumdar, Sean S. Kohles Jun 2005

Dynamic Matrix Composition In Engineered Cartilage With Stochastic Supplementation Of Growth Factors, Asit K. Saha, J. (Jagannath) Mazumdar, Sean S. Kohles

Mechanical and Materials Engineering Faculty Publications and Presentations

Dynamic extracellular matrix (ECM) synthesis is explored in a hypothesized engineered cartilage construct. Growth (α) and decay (β) rate parameters are developed from a previous engineered cartilage model. The presented mathematical model was constructed from the parameterized experimental data using a deterministic and stochastic examination of ECM synthesis based on a negative feedback control mechanism. A growth factor supplementation is incorporated in a probabilistic mathematical approach. The growth factor component modified an initial deterministic model through a Gaussian white noise fluctuation. As the primary constituents of ECM, the mathematical tool is intended to characterize the probable steady state distribution of …


Cellulose Utilization By Clostridium Thermocellum: Bioenergetics And Hydrolysis Product Assimilation, Yi-Heng P. Zhang, Lee R. Lynd May 2005

Cellulose Utilization By Clostridium Thermocellum: Bioenergetics And Hydrolysis Product Assimilation, Yi-Heng P. Zhang, Lee R. Lynd

Dartmouth Scholarship

The bioenergetics of cellulose utilization by Clostridium thermocellum was investigated. Cell yield and maintenance parameters, Y(X/ATP)True = 16.44 g cell/mol ATP and m = 3.27 mmol ATP/g cell per hour, were obtained from cellobiose-grown chemostats, and it was shown that one ATP is required per glucan transported. Experimentally determined values for G(ATP)P-T (ATP from phosphorolytic beta-glucan cleavage minus ATP for substrate transport, mol ATP/mol hexose) from chemostats fed beta-glucans with degree of polymerization (DP) 2-6 agreed well with the predicted value of (n-2)/n [corrected] (n = mean cellodextrin DP assimilated). A mean G(ATP)(P-T) value of 0.52 +/- 0.06 was calculated …


Effect Of Fat And Casein Particles In Milk On The Scattering Of Elliptically Polarized Light, Czarena L. Crofcheck, Jeremie Wade, Janakiraman N. Swamy, Mustafa M. Aslan, M. Pinar Mengüç May 2005

Effect Of Fat And Casein Particles In Milk On The Scattering Of Elliptically Polarized Light, Czarena L. Crofcheck, Jeremie Wade, Janakiraman N. Swamy, Mustafa M. Aslan, M. Pinar Mengüç

Biosystems and Agricultural Engineering Faculty Publications

In this article, we present an experimental approach to determine the milk fat content using scattered light intensity profiles. The elements of the scattering (Mueller) matrix have been shown to provide valuable information about variation of the optical properties of scattering particles. The scattering behavior of fat and casein in terms of the scattering matrix elements was experimentally determined for milk with varying fat levels ranging from 0.05 wt% (skim) to 3.20 wt% (whole). Three of the scattering Mueller matrix elements, specifically S11, S12/S11, and S33/S11, were found to be …


Airflow Resistance Of Seeds At Different Bulk Densities Using Ergun's Equation, Marek Molenda, Michael D. Montross, Samuel G. Mcneill, Jozef Horabik May 2005

Airflow Resistance Of Seeds At Different Bulk Densities Using Ergun's Equation, Marek Molenda, Michael D. Montross, Samuel G. Mcneill, Jozef Horabik

Biosystems and Agricultural Engineering Faculty Publications

Airflow resistance of grains and oilseeds has been extensively studied. Traditionally the data has been presented using Shedd’s curves. However, this assumes that airflow resistance is independent of grain depth. Grain undergoes compaction during storage that changes the bulk density, porosity, and therefore the airflow resistance. Ergun’s equation is a function of particle size and porosity of the granular material. Airflow resistance by Ergun’s equation was used to predict the pressure drop across a column of corn, soft white winter wheat, soft red winter wheat, and soybeans at three moisture content levels and two bulk densities. The maximum root mean …


Permeability Of Corn, Soybeans, And Soft Red And White Winter Wheat As Affected By Bulk Density, Michael D. Montross, Samuel G. Mcneill May 2005

Permeability Of Corn, Soybeans, And Soft Red And White Winter Wheat As Affected By Bulk Density, Michael D. Montross, Samuel G. Mcneill

Biosystems and Agricultural Engineering Faculty Publications

Darcy’s law is a function of viscosity, permeability, and velocity and can be used to predict the airflow resistance in granular materials at low air velocities. Permeability also governs the magnitude of natural convection currents during periods of non-aerated grain storage. The permeability of corn, soybeans, soft white winter wheat, and soft red winter wheat were measured as a function of bulk density and moisture content. Air was passed through a column of grain and the flow rate and pressure drop measured. Bulk density and kernel density were also measured to determine the porosity of grain in the test column. …


Crop Yield Response To Precision Deep Tillage, Larry G. Wells, Timothy S. Stombaugh, Scott A. Shearer May 2005

Crop Yield Response To Precision Deep Tillage, Larry G. Wells, Timothy S. Stombaugh, Scott A. Shearer

Biosystems and Agricultural Engineering Faculty Publications

Experimental precision deep tillage was applied at three sites in central Kentucky with relatively well-drained silt loam soils in no-till crop production. Fields were divided into 0.4 ha (1 ac) grid cells using DGPS mapping. Assessment of soil compaction by machinery traffic was made using multiple soil cone penetrometer measurements and expressed as cone index (CI). Corn, wheat, and soybean yields were depressed in grid cells with CIavg ≥ 1.5 MPa (218 psi) prior to application of tillage treatments at sites 1 and 3, whereas at site 2, where most of the highest average CI values ranged from 1.44 …


Glucose Oxidase (God)-Coupled Amperometric Microsensor With Integrated Electrochemical Actuation System, Jongwon Park, Chang-Soo Kim, Minsu Choi, Shanrui Zhang May 2005

Glucose Oxidase (God)-Coupled Amperometric Microsensor With Integrated Electrochemical Actuation System, Jongwon Park, Chang-Soo Kim, Minsu Choi, Shanrui Zhang

Electrical and Computer Engineering Faculty Research & Creative Works

Recent developments for biosensors have been mainly focused on miniaturization and exploratory use of new materials. It should be emphasized that the absence of a novel "in-situ self-calibration/diagnosis technique" that is not connected to an external apparatus is a key obstacle to the realization of a biosensor for continuous use with minimum attendance. In order to address this issue, a novel solid-state glucose oxidase-coupled amperometric biosensor with integrated electrochemical actuation system has been designed and validated. There are two key components of the proposed glucose biosensor: solid-state GOD-coupled thin-lm amperometric sensing element and O2 depleting/saturating built-in electrochemical actuator. The …


Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick Apr 2005

Identification And Expansion Of Pancreatic Stem/Progenitor Cells., You-Qing Zhang, Marcie Kritzik, Nora Sarvetnick

Journal Articles: Regenerative Medicine

Pancreatic islet transplantation represents an attractive approach for the treatment of diabetes. However, the limited availability of donor islets has largely hampered this approach. In this respect, the use of alternative sources of islets such as the ex vivo expansion and differentiation of functional endocrine cells for treating diabetes has become the major focus of diabetes research. Adult pancreatic stem cells /progenitor cells have yet to be recognized because limited markers exist for their identification. While the pancreas has the capacity to regenerate under certain circumstances, questions where adult pancreatic stem/progenitor cells are localized, how they are regulated, and even …


Controller Area Network Based Distributed Control For Autonomous Vehicles, Matthew J. Darr, Timothy S. Stombaugh, Scott A. Shearer Mar 2005

Controller Area Network Based Distributed Control For Autonomous Vehicles, Matthew J. Darr, Timothy S. Stombaugh, Scott A. Shearer

Biosystems and Agricultural Engineering Faculty Publications

The goal of this project was to evaluate the potential of a controller area network (CAN bus) to be used as the communication network for a distributed control system on an autonomous agricultural vehicle. The prototype system utilized microcontroller-driven nodes to act as control points along a CAN bus. Messages were transferred to the steering, transmission, and hitch control nodes via a task computer. The task computer utilized global positioning system data to generate appropriate control commands. Laboratory and field testing demonstrated that each of the control nodes could function simultaneously over the CAN bus. Results showed that the task …


Ua1b1/7 Complex For Engineering & Biological Sciences Dedication, Western Kentucky University Jan 2005

Ua1b1/7 Complex For Engineering & Biological Sciences Dedication, Western Kentucky University

WKU Archives Records

Program for the Complex for Engineering & Biological Sciences dedication, includes image of the building and floor plans.


Aeration Strategies And Fan Cost Comparisons For Wheat In Mid-South Production Regions, Thomas C. Bridges, Michael D. Montross, Samuel G. Mcneill Jan 2005

Aeration Strategies And Fan Cost Comparisons For Wheat In Mid-South Production Regions, Thomas C. Bridges, Michael D. Montross, Samuel G. Mcneill

Biosystems and Agricultural Engineering Faculty Publications

Numerous factors influence the sizing of aeration fans for summer-harvested crops. Thirty years of weather data for Lexington, Kentucky, were analyzed and the cost of aeration was compared for two axial fans (afan1, afan2) and one centrifugal fan (cfan1). Aeration costs were defined as the sum of the following components: the cost of owning the fan, the cost of electricity for operating the fan, a cost for wheat shrinkage during aeration, and a cost for dry matter loss (DML). The fans were selected to deliver airflow rates of approximately one, two, and three times the recommended aeration rate of 0.11 …


A Multiple-Objective Decision Analysis Of Stakeholder Values To Identify Watershed Improvement Needs, Jason R. W. Merrick, Gregory S. Parnell, Jamison Barnett, Margot Garcia Jan 2005

A Multiple-Objective Decision Analysis Of Stakeholder Values To Identify Watershed Improvement Needs, Jason R. W. Merrick, Gregory S. Parnell, Jamison Barnett, Margot Garcia

Statistical Sciences and Operations Research Publications

The paper describes the use of multiple objective decision analysis to qualitatively and quantitatively assess the quality of an endangered watershed and guide future efforts to improve the quality of the watershed. The Upham Brook watershed is an urban watershed that lies at the interface of declining inner city Richmond, Virginia and growth-oriented Henrico County. A section of stream within the watershed has been identified as so dangerously polluted that it threatens the health of the residents who live within the watershed boundaries. With funding provided by the National Science Foundation, the Upham Brook watershed project committee was formed to …


Medical Technology: Contexts And Content In Science And Technology, Michael A. De Miranda, Mark Doggett, Jane T. Evans Jan 2005

Medical Technology: Contexts And Content In Science And Technology, Michael A. De Miranda, Mark Doggett, Jane T. Evans

Architectural and Manufacturing Sciences Faculty Publications

No abstract provided.


A General Recurrent Neural Network Approach To Model Genetic Regulatory Networks, Xiao Hu, Anne M. Maglia, Donald C. Wunsch Jan 2005

A General Recurrent Neural Network Approach To Model Genetic Regulatory Networks, Xiao Hu, Anne M. Maglia, Donald C. Wunsch

Biological Sciences Faculty Research & Creative Works

There is an urgent need for tools to unravel the complex interactions and functionalities of genes. As such, there has been much interest in reverse-engineering genetic regulatory networks from time series gene expression data. We use an artificial neural network to model the dynamics of complicated gene networks and to learn their parameters. The positive and negative regulations of genes are defined by a weight matrix, and different genes are allowed to have different decaying time constants. We demonstrate the effectiveness of the method by recreating the SOS DNA Repair network of Escherichia coli bacterium, previously discovered through experimental data.


Kentucky Water Resources Research Institute Annual Technical Report Fy 2004, Kentucky Water Resources Research Institute, University Of Kentucky Jan 2005

Kentucky Water Resources Research Institute Annual Technical Report Fy 2004, Kentucky Water Resources Research Institute, University Of Kentucky

KWRRI Annual Technical Reports (USGS’s 104b Grant Program)

The FY 2004 Annual Technical Report for Kentucky consolidates reporting requirements of the Section 104(b) base grant award in a single technical report that includes: 1) a synopsis of each research project supported during the period, 2) a list of related reports, 3) a description of information transfer activities, 4) a summary of student support during the reporting period, and 5) notable achievements and awards during the year.


Streambank Erosion Associated With Grazing Practices In The Humid Region, Carmen T. Agouridis, Dwayne R. Edwards, Stephen R. Workman, José R. Bicudo, Benjamin K. Koostra, Eric S. Vanzant, Joseph L. Taraba Jan 2005

Streambank Erosion Associated With Grazing Practices In The Humid Region, Carmen T. Agouridis, Dwayne R. Edwards, Stephen R. Workman, José R. Bicudo, Benjamin K. Koostra, Eric S. Vanzant, Joseph L. Taraba

Biosystems and Agricultural Engineering Faculty Publications

The effects of cattle grazing on stream stability have been well documented for the western portion of the U.S., but are lacking for the east. Stream and riparian damage resulting from grazing can include alterations in watershed hydrology, changes to stream morphology, soil compaction and erosion, destruction of vegetation, and water quality impairments. However, few studies have examined the successes of best management practices (BMPs) for mitigating these effects. The objective of this project was to assess the ability of two common BMPs to reduce streambank erosion along a central Kentucky stream. The project site consisted of two replications of …


Seed Storage Reserves And Glucosinolates In Brassica Rapa L. Grown On The International Space Station, M. E. Musgrave, Anxiu Kuang, L. K. Tuominen, L. H. Levine, R. C. Morrow Jan 2005

Seed Storage Reserves And Glucosinolates In Brassica Rapa L. Grown On The International Space Station, M. E. Musgrave, Anxiu Kuang, L. K. Tuominen, L. H. Levine, R. C. Morrow

Biology Faculty Publications and Presentations

Although plants are envisioned to play a central role in life support systems for future long-duration space travel, plant growth in space has been problematic due to horticultural problems of nutrient delivery and gas resupply posed by the weightless environment. Iterative improvement in hardware designed for growth of plants on orbital platforms now provides confidence that plants can perform well in microgravity, enabling investigation of their nutritional characteristics. Plants of B. rapa (cv. Astroplants) were grown in the Biomass Production System on the International Space Station. Flowers were hand-pollinated and seeds were produced prior to harvest at 39 days after …


Ridding Ships' Ballast Water Of Microorganisms, Fred C. Dobbs, Andrew Rogerson Jan 2005

Ridding Ships' Ballast Water Of Microorganisms, Fred C. Dobbs, Andrew Rogerson

OES Faculty Publications

( First paragraph) A complex assemblage of microorganisms exists in nearly every aquatic system on earth. In lakes and oceans, every milliliter of water contains about 102 protists (single-celled eukaryotes), 106 bacteria, and 107–109 viruses. Therefore, billions of microorganisms inevitably enter ships’ ballast tanks during normal operations. It has been argued that microorganisms must certainly be frequent invaders of coastal ecosystems, given the high densities of bacteria and viruses in ballast water—108 and 109 organisms per liter, respectively (1)—their potentially high reproductive rates, broad tolerances to physical conditions, and ability to form resting …


Selective Field Effects On Intracellular Vacuoles And Vesicle Membranes With Nanosecond Electric Pulses, Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov, Juergen F. Kolb, Karl H. Schoenbach Jan 2005

Selective Field Effects On Intracellular Vacuoles And Vesicle Membranes With Nanosecond Electric Pulses, Ephrem Tekle, Hammou Oubrahim, Sergey M. Dzekunov, Juergen F. Kolb, Karl H. Schoenbach

Bioelectrics Publications

Electric pulses across intact vesicles and cells can lead to transient increase in permeability of their membranes. We studied the integrity of these membranes in response to external electric pulses of high amplitude and submicrosecond duration with a primary aim of achieving selective permeabilization. These effects were examined in two separate model systems comprising of 1), a mixed population of 1,2-di-oleoyl-sn-glycero-3-phosphocholine phospholipid vesicles and in 2), single COS-7 cells, in which large endosomal membrane vacuoles were induced by stimulated endocytosis. It has been shown that large and rapidly varying external electric fields, with pulses shorter than the charging time of …


Simulations Of Nanopore Formation And Phosphatidylserine Externalization In Lipid Membranes Subjected To A High-Intensity, Ultrashort Electric Pulse, Q. Hu, R. P. Joshi, K. H. Schoenbach Jan 2005

Simulations Of Nanopore Formation And Phosphatidylserine Externalization In Lipid Membranes Subjected To A High-Intensity, Ultrashort Electric Pulse, Q. Hu, R. P. Joshi, K. H. Schoenbach

Bioelectrics Publications

A combined MD simulator and time dependent Laplace solver are used to analyze the electrically driven phosphatidylserine externalization process in cells. Time dependent details of nanopore formation at cell membranes in response to a high-intensity (100kV∕cm), ultrashort (10ns) electric pulse are also probed. Our results show that nanosized pores could typically be formed within about 5ns. These predictions are in very good agreement with recent experimental data. It is also demonstrated that defect formation and PS externalization in membranes should begin on the anode side. Finally, the simulations confirm that PS externalization is a nanopore facilitated event, rather than the …


A New Microsensor System For Plant Root Zone Monitoring, Chang-Soo Kim, Sandeep Sathyan, D. M. Porterfield Jan 2005

A New Microsensor System For Plant Root Zone Monitoring, Chang-Soo Kim, Sandeep Sathyan, D. M. Porterfield

Electrical and Computer Engineering Faculty Research & Creative Works

The objective of this work is to develop a new microsensor system that can monitor dissolved oxygen and hydration environment at the plant root zone. A miniaturized plant growth system is prepared including the root zone layer, either a porous ceramic tube or porous ceramic wafer on which the plant is grown, and an underlying fluidic channel to deliver nutrients and water to the root zone. We demonstrate the feasibility of using a flexible microsensor array for dissolved oxygen detection, and a four-electrode impedance microelectrode for wetness detection on the surface of a porous tube nutrient delivery system. The unique …


An Efficient Method For Supporting Multiple Types Of Services On Smart Server, Chang-Soo Kim, Yu-Hyeon Bak, Seung-Joe Bae, Jin-Mee Kim, Sang-Min Woo, Seung-Hyup Jeon, Won-Jae Lee, Hag-Young Kim Jan 2005

An Efficient Method For Supporting Multiple Types Of Services On Smart Server, Chang-Soo Kim, Yu-Hyeon Bak, Seung-Joe Bae, Jin-Mee Kim, Sang-Min Woo, Seung-Hyup Jeon, Won-Jae Lee, Hag-Young Kim

Electrical and Computer Engineering Faculty Research & Creative Works

No abstract provided.


Influence Of Oxygen Microenvironment On Microfluidic Glucose Sensor Performance, Chang-Soo Kim, Jongwon Park Jan 2005

Influence Of Oxygen Microenvironment On Microfluidic Glucose Sensor Performance, Chang-Soo Kim, Jongwon Park

Electrical and Computer Engineering Faculty Research & Creative Works

We propose a novel method to overcome significant problems of baseline drift and sensitivity degradation in amperometric biosensors based on oxidase enzyme reactions. A novel glucose microsensor with a built-in electrochemical oxygen manipulation microsystem is introduced to demonstrate three novel functionalities; one-point in situ self-calibration (zero-point), broadening of dynamic range and increase in sensitivity. The influence of electrochemically generated oxygen microenvironment on the sensor output within a fluidic structure is investigated.