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Full-Text Articles in Engineering

Improving And Modeling Bacteria Recovery In Hollow Disk System, Clifton Anderson Aug 2019

Improving And Modeling Bacteria Recovery In Hollow Disk System, Clifton Anderson

Theses and Dissertations

Identifying antibiotic resistance in blood infections requires separating bacteria from whole blood. A hollow spinning disk rapidly removes suspended red blood cells by leveraging hydrodynamic differences between bacteria and whole blood components in a centrifugal field. Once the red cells are removed, the supernatant plasma which contains bacteria is collected for downstream antibiotic testing. This work improves upon previous work by modifying the disk design to maximize fractional plasma recovery and minimize fractional red cell recovery. V-shaped channels induce plasma flow and increase fractional plasma recovery. Additionally, diluting a blood sample spiked with bacteria prior to spinning it increased the …


Beating Clusters Created With Cardiac Extracellular Matrix From Decellularized Pig Hearts And Repopulated With Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Isaac Myres, Bryce Allen, Silvia Moncada, Sebastian Valencia, Beverly L. Roeder, Alonzo D. Cook Jan 2019

Beating Clusters Created With Cardiac Extracellular Matrix From Decellularized Pig Hearts And Repopulated With Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes, Isaac Myres, Bryce Allen, Silvia Moncada, Sebastian Valencia, Beverly L. Roeder, Alonzo D. Cook

Library/Life Sciences Undergraduate Poster Competition 2019

Due to the high prevalence of heart disease, scarcity of donors, and high risk of transplant rejection, we aim to engineer patient specific beating cardiac patches and whole hearts for transplant.