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Investigations Into Rates And Mechanisms Of Mercury Depuration In The Killifish, Fundulus Heteroclitus, Joanne A. Korpanty
Investigations Into Rates And Mechanisms Of Mercury Depuration In The Killifish, Fundulus Heteroclitus, Joanne A. Korpanty
Theses
Metallothionein (MT) and glutathione (GSH) have been shown in mammalian research to play a role in the sequestration and depuration of mercury. The sulfhydryl groups on both these peptides have a strong affinity for mercury, MT for Hg2+ and GSH for CH3Hg+. In this study, killifish (Fundulus heteroclitus) were force-fed one piece of squid laced with labelled mercuric nitrate to give a final food concentration of 20 ppm 203Hg2+ and 0.03 -0.05 µg g-1 Hg2+ total dose. Most of the mercury, 84.1 ± 12.1% (mean ± standard deviation), is depurated within the …