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Full-Text Articles in Engineering

Evaluation Of Terahertz Imaging For Breast Cancer Detection Using Image Morphing, Tanny Andrea Chavez Esparza May 2018

Evaluation Of Terahertz Imaging For Breast Cancer Detection Using Image Morphing, Tanny Andrea Chavez Esparza

Graduate Theses and Dissertations

This thesis proposes the use of a mesh morphing algorithm for the quantitative evaluation of terahertz (THz) images. This work differs from traditional evaluation methods based on qualitative evaluation because it provides a fair and quantitative measurement of the THz imaging system's performance. The objective of the algorithm is to match the alignment, shape, and resolution of the THz and reference pathology images. Therefore, the proposed morphing method provides a pathology reference for a pixel-by-pixel evaluation of the region classification in the THz image. To achieve this, the morphing algorithm aligns the images using the Pearson's correlation coefficient and reshapes …


3d Bioprinting Systems For The Study Of Mammary Development And Tumorigenesis, John Reid Apr 2018

3d Bioprinting Systems For The Study Of Mammary Development And Tumorigenesis, John Reid

Electrical & Computer Engineering Theses & Dissertations

Understanding the microenvironmental factors that control cell function, differentiation, and stem cell renewal represent the forefront of developmental and cancer biology. To accurately recreate and model these dynamic interactions in vitro requires both precision-controlled deposition of multiple cell types and well-defined three-dimensional (3D) extracellular matrix (ECM). To achieve this goal, we hypothesized that accessible bioprinting technology would eliminate the experimental inconsistency and random cell-organoid formation associated with manual cell-matrix embedding techniques commonly used for 3D, in vitro cell cultures. The first objective of this study was to adapt a commercially-available, 3D printer into a 3D bioprinter. Goal-based computer simulations were …


Hyperspectral Imaging And K-Means Classification For Histologic Evaluation Of Ductal Carcinoma In Situ, Yasser Khouj, Jeremy Dawson, James Coad, Linda Vona-Davis Jan 2018

Hyperspectral Imaging And K-Means Classification For Histologic Evaluation Of Ductal Carcinoma In Situ, Yasser Khouj, Jeremy Dawson, James Coad, Linda Vona-Davis

Faculty & Staff Scholarship

Hyperspectral imaging (HSI) is a non-invasive optical imaging modality that shows the potential to aid pathologists in breast cancer diagnoses cases. In this study, breast cancer tissues from different patients were imaged by a hyperspectral system to detect spectral differences between normal and breast cancer tissues. Tissue samples mounted on slides were identified from 10 different patients. Samples from each patient included both normal and ductal carcinoma tissue, both stained with hematoxylin and eosin stain and unstained. Slides were imaged using a snapshot HSI system, and the spec- tral reflectance differences were evaluated. Analysis of the spectral reflectance values indicated …


A Novel Multistage System For The Detection And Removal Of Pectoral Muscles Inmammograms, İdi̇l Işikli Esener, Semi̇h Ergi̇n, Tolga Yüksel Jan 2018

A Novel Multistage System For The Detection And Removal Of Pectoral Muscles Inmammograms, İdi̇l Işikli Esener, Semi̇h Ergi̇n, Tolga Yüksel

Turkish Journal of Electrical Engineering and Computer Sciences

In this paper, a novel multistage scheme for pectoral muscle removal from mammography images is proposed, and the performance of this system is verified using the publicly available Mammographic Image Analysis Society digital mammogram database. This database is composed of mediolateral oblique mammography images including three different tissue types (fatty, fatty-glandular, and dense-glandular) with three health status types (normal, benign cancer, and malignant cancer). In the implementation of the proposed system, a mammography image is first preprocessed by performing noise reduction background removal followed by artifact suppression processes. Then a presegmentation procedure is applied using region growing and line fitting …