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An Analytical And Experimental Biosensor For Human Mig Using Algan/Gan Based Hemt Devices, Hector Trevino Ii
An Analytical And Experimental Biosensor For Human Mig Using Algan/Gan Based Hemt Devices, Hector Trevino Ii
Theses and Dissertations - UTB/UTPA
An amperometric biosensor using AlGaN/GaN based HEMT devices is constructed experimentally and validated through analytical and numerical techniques for detection of a key protein in allograft rejection (Human MIG/CXCL9). The prototype developed provides a reliable sensing platform that will allow label-free and marker-free detection. By exploiting characteristics unique to AlGaN/GaN based HEMT devices, a floating gate configuration is employed to allow reliable sensing without the need for any reference electrode. Self-assembled monolayers (SAM) are formed at the gate surface by using a crosslinker (DSP) to allow for appropriate immobilization of target antibodies. A theoretical analytical and numerical model is developed …