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Microfluidic Enhanced Fabry-Perot Etalon Based Optical Biosensor For The Detection Of Biological Substances In Liquid With Refractive Index Measurement, Nezam Uddin

Electronic Theses and Dissertations

A new microfluidic optical biosensor was demonstrated for refractive index measurements with high sensitivity and accuracy in the range of few micrometers liquid channels utilizing a Fabry-Perot cavity formed between two reflective semitransparent surfaces. The transmitted light through the cavity forms interference peaks in the transmission spectrum which is dependent upon the refractive index of the fluid in the microfluidic channel. We demonstrate the biosensor using Fabry-Perot to provide high accuracy and sensitivity with real-time measurement. The sensor can resolve refractive index changes with the shift of peak wavelength of transmitted spectrum. In our Fabry- Perot etalon based biosensor, two …