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Full-Text Articles in Engineering
Creating Clinically Useful In Silico Models Of Intracranial Pressure Dynamics, Wayne W. Wakeland, Joe Fusion, Brahm Goldstein
Creating Clinically Useful In Silico Models Of Intracranial Pressure Dynamics, Wayne W. Wakeland, Joe Fusion, Brahm Goldstein
Systems Science Faculty Publications and Presentations
To create clinically useful computer simulation models of intracranial pressure (ICP) dynamics by using prospective clinical data to estimate subject-specific physiologic parameters.
Calibrating An Intracranial Pressure Dynamics Model With Clinical Data - A Progress Report, Wayne W. Wakeland, James Mcnames, Brahm Goldstein
Calibrating An Intracranial Pressure Dynamics Model With Clinical Data - A Progress Report, Wayne W. Wakeland, James Mcnames, Brahm Goldstein
Systems Science Faculty Publications and Presentations
We describe the calibration of a computer model of intracranial pressure (ICP) dynamics to correspond with annotated clinical data taken from a patient being treated for elevated ICP due to a traumatic brain injury. The research protocol employed during treatment includes adjusting the elevation of the head of the bed, adjusting the ventilator settings to induce mild hyperventilation and hypoventilation, and adjusting the height of the cerebrospinal fluid drainage system. The model behavior corresponds to the experimental data quite well in the case of the changing the head of the bed, but less well in the case of changing the …