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Full-Text Articles in Engineering
Deciphering The Rules Of Cell-To-Cell Coupling By Molecular Modeling And Simulation, Linda D. Lee
Deciphering The Rules Of Cell-To-Cell Coupling By Molecular Modeling And Simulation, Linda D. Lee
REU Final Reports
Intercellular communication is vital for quick adjustments and maintenance for cell function and development. Gap junctions are membranes channel proteins that enable this direct communication between adjacent cells throughout the body. The compatibility of connexins (Cx), which make up a gap junction, determines whether a gap junction can form. Though many studies show which connexins are compatible, the molecular basis is not known (Bai & Wang, 2014). Through computational modeling, we identify the residues that energetically contribute most favorably at the docking interface of homotypic and heterotypic combinations of Cx43, Cx46, and Cx50 gap junctions. However, due to instability of …
Associative Learning In Biochemical Networks, Yasmin S. Sepulveda
Associative Learning In Biochemical Networks, Yasmin S. Sepulveda
REU Final Reports
Emerging evidence suggests that biochemical networks can be modeled by exploiting their ability to learn through associative learning. This type of learning in biomolecular structures gives it a the advantage to be able to be computationally model, and condition. Associative learning in biochemical networks is a developing area of study that once understood, can further develop diagnostic applications, and be used as tools for data analysis. Although it is a open ended project the motive of this research was to find the the best method of association learning being used in current work. After reading current work three associative learning …