Engineering Commons^™

Understanding The Mechanism Of Deep Learning Frameworks In Lesion Detection For Pathological Images With Breast Cancer, Wei-Wen Hsu, Chung-Hao Chen, Chang Hao, Yu-Ling Hou, Xiang Gao, Yun Shao, Xueli Zhang, Jingjing Wang, Tao He, Yanhong Tai

Electrical & Computer Engineering Faculty Publications

With the advances of scanning sensors and deep learning algorithms, computational pathology has drawn much attention in recent years and started to play an important role in the clinical workflow. Computer-aided detection (CADe) systems have been developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing misdetections. In this study, we conducted four experiments to demonstrate that the features learned by deep learning models are interpretable from a pathological perspective. In addition, classifiers such as the support vector machine (SVM) and random forests (RF) were used in experiments to replace the fully connected layers and decompose the end-to-end …