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Patterns Of Dipeptide Usage For Gene Prediction, Dayananda Sagar Gangadharaiah
Patterns Of Dipeptide Usage For Gene Prediction, Dayananda Sagar Gangadharaiah
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As the number of complete genomes that have been sequenced continues to grow rapidly, the identification of genes regions in DNA sequence data remains one of the most important open problems in bio-informatics. Improving the accuracy of such gene finding tools by a small percentage would affect accurate predictions of many genes of an organism (Zhu et al., 2010). This thesis presents a novel approach for identifying coding regions of a genome based on dipeptide usage.
The patterns in dipeptide usage are used to discriminate between coding and non-coding DNA regions. Two sample T-tests are used as tests of significance …