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Field Amplified Sample Stacking On Amyloid Beta (1-42) Oligomers Using Capillary Electrophoresis, Sadia Ali Paracha

Graduate Theses and Dissertations

According to recent literature, it is believed that the oligomeric form of amyloid beta (Aβ) is the leading cause of Alzheimer’s disease (1; 8; 10; 12-18). Additionally, recent studies have eluded to the impact of Alzheimer’s disease (AD) both economically and Socially in today’s society where an increase of about 71% of AD related deaths were recorded between 2000 and 2013 (7). Since the oligomeric forms of Aβ vary in size, shape and some believe conformation, it is vital to utilize a separation technique, such as capilllary electrophoresis (CE) to further understand Aβ aggregation. By understanding Aβ aggregation, treatment of …