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Full-Text Articles in Engineering
Aspen Plus Simulation Of Biomass Gasification In A Steam Blown Dual Fluidised Bed, Wayne Doherty, Anthony Reynolds, David Kennedy
Aspen Plus Simulation Of Biomass Gasification In A Steam Blown Dual Fluidised Bed, Wayne Doherty, Anthony Reynolds, David Kennedy
Book/Book Chapters
The efficient utilisation of biomass resources is of utmost importance. Biomass gasification offers much higher efficiencies than combustion. Gasification is a process in which a fuel is converted to a combustible gas (syngas). A dual fluidised bed gasifier known as the fast internally circulating fluidised bed (FICFB) was selected. It has been demonstrated at industrial scale and data is readily available for model validation. An Aspen Plus model was developed to simulate the FICFB gasifier. The model is based on Gibbs free energy minimisation and the restricted equilibrium method was used to calibrate it. The model has been validated and …
The Effects Of Mismatches And Probe Tethering Configurations On The Stability Of Dna Duplexes On Surfaces, Kyle Evan Pratt
The Effects Of Mismatches And Probe Tethering Configurations On The Stability Of Dna Duplexes On Surfaces, Kyle Evan Pratt
Theses and Dissertations
DNA microarrays are chip-based, analysis tools which can perform hundreds of thousands of parallel assays to determine the identity of genes or gene expression levels present in a sample. They have been identified as a key technology in genomic sciences and emergent medical techniques; however, despite their abundant use in research laboratories, microarrays have not been used in the clinical setting to the fullest potential due to the difficulty of obtaining reproducible results. Microarrays work on the principle of DNA hybridization, and can only be as accurate as this process is robust. Fundamental, molecular-level understanding of hybridization on surfaces is …
Protein-Surface Interactions With Coarse-Grain Simulation Methods, Shuai Wei
Protein-Surface Interactions With Coarse-Grain Simulation Methods, Shuai Wei
Theses and Dissertations
The interaction of proteins with surfaces is a major process involved in protein microarrays. Understanding protein-surface interactions is key to improving the performance of protein microarrays, but current understanding of the behavior of proteins on surfaces is lacking. Prevailing theories on the subject, which suggest that proteins should be stabilized when tethered to surfaces, do not explain the experimentally observed fact that proteins are often denatured on surfaces. This document outlines several studies done to develop a model which is capable of predicting the stabilization and destabilization of proteins tethered to surfaces. As the start point of the research, part …