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The Distribution And Significance Of Anticoagulant-Resistant Norway Rats (Rattus Norvegicus) In England And Wales, 1988-95, Alan D. Macnicoll, Gerard M. Kerbms, Nicola J. Dennis, J. Erica Gill
The Distribution And Significance Of Anticoagulant-Resistant Norway Rats (Rattus Norvegicus) In England And Wales, 1988-95, Alan D. Macnicoll, Gerard M. Kerbms, Nicola J. Dennis, J. Erica Gill
Proceedings of the Seventeenth Vertebrate Pest Conference 1996
Between 1988 and 1995 populations of rats on agricultural premises were sampled to investigate the distribution of anticoagulant-resistant rats in England and Wales. In total, approximately 1,670 rats from 115 locations were tested for resistance to warfarin. Rats that were warfarin-resistant were subsequently tested for resistance to difenacoum, and since 1991 for resistance to bromadiolone. In some cases rats were also tested for resistance to brodifacoum, and in 1995 for resistance to flocoumafen. The results of these tests showed that there was a high prevalence of resistance to the first-generation anticoagulant, warfarin, in several regions of England and Wales. Rats …
Preliminary Study Of The Genetics Of Resistance In The House Mouse, Colin V. Prescott
Preliminary Study Of The Genetics Of Resistance In The House Mouse, Colin V. Prescott
Proceedings of the Seventeenth Vertebrate Pest Conference 1996
A wild house mouse (Mus domesticus) population originally trapped near Reading, Berkshire, United Kingdom, and maintained as a colony in the laboratory, was subjected to the discriminating feeding period of the warfarin resistance test, as used by Wallace and MacSwiney (1976) and derived from the work of Rowe and Redfern (1964). Eighty percent of this heterogeneous population survived the resistance test. A similar proportion of the population was found to survive the normally lethal dose of bromadiolone administered by oral gavage. The majority of this population of mice were classified as "warfarin-resistant" and "bromadiolone-resistant." The dose of l0 …