Open Access. Powered by Scholars. Published by Universities.®
Bioresource and Agricultural Engineering
Department of Biological Systems Engineering: Dissertations and Theses
Articles 1 - 1 of 1
Full-Text Articles in Engineering
Engineering Of Microparticle Encapsulated Antioxidant To Mitigate Oxidative Stress In Vitro And In Vivo, Kayla Ney
Department of Biological Systems Engineering: Dissertations and Theses
Chronic low back pain (cLBP) is one of the leading causes of years lived with disability in the United States. Current treatments for cLBP have variable results across the patient population, and many patients struggle to find consistent relief. Most current treatments focus on the symptom of pain, not the root cause. In painful degenerated discs, oxidative stress and inflammation function in a vicious cycle and perpetuate degeneration, damage, and pain. Therefore, oxidative stress and inflammation are important targets in addressing the source of pain. This work characterizes an antioxidant, BuOE, encapsulated in a chondroitin sulfate microparticle as a novel …