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Full-Text Articles in Engineering
Improving Quantification Of Mitral Regurgitation Through Computational Fluid Dynamics And Ex Vivo Testing, Alexandra Flowers
Improving Quantification Of Mitral Regurgitation Through Computational Fluid Dynamics And Ex Vivo Testing, Alexandra Flowers
Electronic Theses and Dissertations
Mitral regurgitation (MR) is a prominent cardiac disease affecting more than two million people in the United States alone. In order for patients to receive proper therapy, regurgitant volume must first be quantified. As there are an array of methods to do so, the proximal isovelocity surface area (PISA) method continues to be the most accurate and clinically used method. However, there are some difficulties obtaining the necessary measurements need for this when performing transthoracic echocardiography. This study aims to evaluate and present techniques that may be used to more accurately quantify regurgitation through ex vivo testing and computational fluid …
Detection Method Of Subclinical Atherosclerosis Of The Carotid Artery With A Hemodynamics Modeling Approach, Marisa Peressini
Detection Method Of Subclinical Atherosclerosis Of The Carotid Artery With A Hemodynamics Modeling Approach, Marisa Peressini
Master's Theses
Subclinical atherosclerosis is an important area of research to evaluate stroke risk and predict localization of plaque. The current methods for detecting atherosclerosis risk are insufficient because it is based on The Framingham Risk Score and carotid intima media thickness, therefore an engineering detection model based on quantifiable data is needed. Laminar and turbulent flow, dictated by Reynolds number and relative roughness, was modeled through the carotid artery bifurcation to compare shear stress and shear rate. Computer-aided design and fluid flow software were used to model hemodynamics through the carotid artery. Data from the model was derived from governing equations …
Multi-Level Parallelism For Incompressible Flow Computations On Gpu Clusters, Dana A. Jacobsen, Inanc Senocak
Multi-Level Parallelism For Incompressible Flow Computations On Gpu Clusters, Dana A. Jacobsen, Inanc Senocak
Mechanical and Biomedical Engineering Faculty Publications and Presentations
We investigate multi-level parallelism on GPU clusters with MPI-CUDA and hybrid MPI-OpenMP-CUDA parallel implementations, in which all computations are done on the GPU using CUDA. We explore efficiency and scalability of incompressible flow computations using up to 256 GPUs on a problem with approximately 17.2 billion cells. Our work addresses some of the unique issues faced when merging fine-grain parallelism on the GPU using CUDA with coarse-grain parallelism that use either MPI or MPI-OpenMP for communications. We present three different strategies to overlap computations with communications, and systematically assess their impact on parallel performance on two different GPU clusters. Our …
One-Dimensional Radial Diffusion Of Small Molecules (376 Da) In Bone Tissue, Kurt W. Farrell
One-Dimensional Radial Diffusion Of Small Molecules (376 Da) In Bone Tissue, Kurt W. Farrell
ETD Archive
The flow of nutrients through any biological tissue is important to maintain homeostasis. If the transport process is understood, medical research teams can better design medications, prosthetic implants, and tissue scaffolds. Additionally, transport rates help physicians to better understand disease states and wound healing, including minor injuries such as breaks and sprains, which will aid in better diagnoses. We developed a novel method that measures the rate of diffusion in vitro, of fluorescein sodium salt. Samples were incubated at 37°C in a 5 CO2 atmosphere for various periods of time. Samples were sliced and analyzed using Image-Pro Plus and MATLAB …