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Sensorimotor Content Of Multi-Unit Activity In The Paramedian Lobule Of The Cerebellum, Esma Cetinkaya
Sensorimotor Content Of Multi-Unit Activity In The Paramedian Lobule Of The Cerebellum, Esma Cetinkaya
Dissertations
Based on Center for Disease Control and Prevention report 2016, around 39.5 million people in the United States suffer from motor disabilities. These disabilities are due to traumatic conditions like traumatic brain injury (TBI), neurological diseases such as amyotrophic lateral sclerosis (ALS), or congenital conditions. One of the approaches for restoring the lost motor function is to extract the volitional information from the central nervous system (CNS) and control a mechanical device that can replace the function of a paralyzed limb through systems called Brain-Computer Interfaces (BCI).
One of the major challenges being faced in BCIs and also in general …
High Frequency Field Potentials Of The Cerebellar Cortex, Jonathan David Groth
High Frequency Field Potentials Of The Cerebellar Cortex, Jonathan David Groth
Dissertations
The cerebellum plays a crucial role in motor coordination along with basal ganglia and the motor areas of the cerebral cortex. Both somatosensory and the cerebro-cerebral pathways bring in massive amounts of neural information to the cerebellum. The output of the cerebellar cortex projects to various motor cortices as well as down to the spinal cord to make its contributions to the motor function.
The origin and function of the field potential oscillations in the cerebellum, especially in the high frequencies, have not been explored sufficiently. The primary objective of this study was to investigate the spatio-temporal characteristics of high …
Surface Recordings Of Evoked Field Potentials From The Cerebellum With A Flexmea Microelectrode Array, Jonathan David Groth
Surface Recordings Of Evoked Field Potentials From The Cerebellum With A Flexmea Microelectrode Array, Jonathan David Groth
Theses
The cerebellum is an integral part of multijoint control. There are two input pathways to the cerebellar cortex, the mossy fiber and the climbing fiber pathways. The mossy fiber pathway forms a disynaptic input to Purkinje cells through the granular cells. This disynaptic input produces a multicomponent field potential composed of the P1, N 1, N2, N3, N4, and P3 waves. The climbing fiber input forms a monosynaptic input to the Purkinje cells and thus creates a much simpler field potential.
The mossy and climbing fiber field potentials were recorded with a FlexMEA microelectrode array from the pial surface of …