Engineering Commons^™

Can Transcranial Electrical Stimulation Motor Threshold Estimate Individualized Tdcs Doses Over The Prefrontal Cortex? Evidence From Reverse-Calculation Electric Field Modeling, Kevin A. Caulfield, Bashar W. Badran, Xingbao Li, Marom Bikson, Mark S. George

Publications and Research

No abstract provided.

Transcranial Electrical Stimulation Motor Threshold Can Estimate Individualized Tdcs Dosage From Reverse-Calculation Electric-Field Modeling, Kevin A. Caulfield, Bashar W. Badran, William H. Devries, Philipp M. Summers, Emma Kofmehl, Xingbao Li, Jeffrey J. Borckardt, Marom Bikson, Mark S. George

Publications and Research

Background

Unique amongst brain stimulation tools, transcranial direct current stimulation (tDCS) currently lacks an easy or widely implemented method for individualizing dosage.

Objective

We developed a method of reverse-calculating electric-field (E-field) models based on Magnetic Resonance Imaging (MRI) scans that can estimate individualized tDCS dose. We also evaluated an MRI-free method of individualizing tDCS dose by measuring transcranial magnetic stimulation (TMS) motor threshold (MT) and single pulse, suprathreshold transcranial electrical stimulation (TES) MT and regressing it against E-field modeling. Key assumptions of reverse-calculation E-field modeling, including the size of region of interest (ROI) analysis and the linearity of multiple E-field …

Influence Of Transdermal Current Flow In Tdcs-Induced Cutaneous Adverse Events, Niranjan Khadka

Dissertations and Theses

Significant contributors to the broad application of transcranial direct current stimulation (tDCS) are portability, ease-of-use, and tolerability; with adverse events limited to transient and mild cutaneous sensations (e.g. perception of burning, itching, and tingling) and erythema. However, the fundamental questions remain about the mechanism of transdermal current flow during transcranial electrical stimulation, including tDCS. Example of previously unexplained questions in tDCS include: 1) the relationship between tDCS-induced skin reddening (erythema) profile and local current density profile predicted by the model; 2) the source of burning sensation during tDCS and whether it is related to an actual skin heating; 3) the …