Engineering Commons^™

Exploring The Use Of Virtual Reality In Designing And Prototyping Medical Devices, Evan Marsh

Honors Theses

A degree in engineering is highly sought after in the United States. Despite the grueling coursework and sacrifices involved in earning an engineering degree, the rewards after college are numerous. However, the engineering field is vast, and the degree obtained is not always the profession followed in industry. A lot of what we learn in the college of engineering is very broad and surface-level. It is worth noting that only about 10% of what engineering students learn in school is applicable in the workplace, but they wish they had learned a lot more about that 10%.

The Antler: The Design And Development Of An Independent Shower Support Stand For Those Living With Lower Extremity Limb Loss, Kylie Wright

Honors Theses

While we do not often think about it, taking a shower is a privilege. Standing in the hot water, cleaning off after a long day outdoors, and taking a moment to simply relax is an experience that most people in the U.S. have participated in. However, about 1.4 million Americans do not have this luxury3. Lower extremity amputees have long been advised to shower while seated for their safety. This population is unable to experience the simple independence that accompanies standing in the shower. Despite the growing rate of amputations each year, no products are currently available on the market …

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Shelby Lynn Berry, Sydney Ruth Rester

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

Redesigning Nasogastric Feeding Tubes To Prevent Dislodgement, Sydney Ruth Rester, Shelby Lynn Berry

Honors Theses

Seniors at the University of Mississippi studying biomedical engineering complete a senior project that seeks to solve a problem in healthcare. Our team, composed of Sydney Rester, Shelby Berry, Andrew Ulmer, and Alex Bromley, sought to improve care associated with nasogastric feeding tubes. We identified two major problems: clogging and tube dislodgement. To address the problem of dislodgement, the team crafted a new feeding tube design with a balloon attachment. The attachment prevents a patient from pulling the feeding tube out and keeps the tube from dislodging due to normal patient movement. We further determined that our tube should be …

A Device For Measuring Acoustic Output Intensity Of Transcranial Doppler Ultrasound Transducers For Comparison With Fda Regulations, Sarah Altman, Gregory Bashford, Benjamin Hage

Honors Theses

Transcranial Doppler Ultrasonography (TCD) is a non-invasive methodology which can evaluate cerebral blood flow velocity in real time. Single-element focused circular transducers placed on the scalp produce ultrasound waves capable of penetrating the skull with minimal aberration, enabling measurement of the Doppler shift. As such, TCD can measure blood flow velocity in the internal carotid and vertebral arteries, as well as the arteries of the Circle of Willis: the Anterior Cerebral (ACA), Posterior Cerebral (PCA), and Middle Cerebral Arteries (MCA). Intracranial aneurysm and ischemic stroke are serious conditions in which ballooning or occlusion of cerebral vessels cause insufficient perfusion, leading …

Simpliscope: A Novel Device For In-Office Laryngeal Biopsies, Margaret Schuermann, Aris Rassias, Noah Barney, Alexandra Lipsky

Honors Theses

In order to screen for laryngeal cancer, a biopsy is performed to take a tissue sample from that area of interest. Due to the risk involved these procedures take place in the operating room where a larger sample can be obtained, but delays in scheduling operating room procedures put patients at a greater risk as their diagnosis can be delayed. We want to create a device that is able to move these delayed operating room procedures in-of ice where the physician can treat the patient quickly and safely. Our goal is to increase the accuracy of in-office laryngeal biopsies while …

Increasing Accessibility To Monitoring Ammonia Levels In The Body Through Development Of A Novel Point-Of-Care Breath Ammonia Diagnostic Device, Emily C. Wright, Ashwin M. Sivalingam

Honors Theses

Hyperammonemia is a life-threatening metabolic condition that is characterized by elevated levels of ammonia concentrations in the blood. Resulting from serious conditions such as chronic kidney disease or liver failure, the limited functions of the liver and kidney lead to an increase in blood urea nitrogen (BUN) within the body. Currently, there are a wide variety of treatments for this condition, ranging from various medications to surgical procedures such as liver transplants. However, there is a lack of variety in diagnostic testing methods to determine a patient’s ammonia levels. In most cases, patients will need to schedule a doctor’s appointment …

Device For Affixation Of Rear-Facing Child Restraint System To Ambulance Cot For Non-Emergent Transport, Troy Kohler, Kendall Rogoff, Matthew Miller, Lily Buchanan

Honors Theses

During motor vehicle travel it is a near-universal practice to transport infants in a rear-facing car seat, formally known as a child restraint system (CRS). Car seats are subject to heavy regulations, extensive testing, and are safe, secure, and familiar environments for infants. The use of a CRS reduces fatalities associated with motor vehicle collisions by up to 71%. Current devices on the market for pre-hospital infant transport are harness-based and do not utilize these car seats. Aversion to use of these harnesses occurs for a variety of reasons. The device becomes visually unattractive after remaining in storage for long …

K-Wire Differentiation, Oluwadamilola Oluwadara, Lillian Maresco, Eunjung Lee, Michelle De Leon

Honors Theses

Kirschner Pins, known as K-wires, are smooth sharp stainless steel pins used in the field of orthopedics to stabilize bone fracture fragments in their correct position until they have fully healed. K-wires are most commonly used for comminuted metaphyseal fractures of the long bones, and fractures of smaller bones such as the phalanges. The wires are inserted into bone via a drill and the ends of the wire are bent and left outside of the body for easy removal once the bone has healed. The surgeon uses x-ray images to guide K-wire insertion, ensure proper internal alignment, and determine if …

Improving The Efficacy Of Epinephrine Delivery For Anaphylaxis Through Development Of A Novel Auto-Injector Device And Increased User Education, Jennifer Ansley Myers

Honors Theses

Anaphylaxis is a life-threatening condition caused by the body’s overreaction to a certain allergen. The most widely accepted treatment for this condition is immediate administration of epinephrine, a hormone secreted by the adrenal glands that initiates the body’s fight or flight response, through an intramuscular injection. In most cases, patients that experience anaphylaxis are prescribed an epinephrine auto-injector to carry with them at all times which contains a single dose of epinephrine. Though these devices have been widely accepted for many years, there are many problems caused by their design and the lack of training that their users receive. The …

Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price

Honors Theses

ABSTRACT JASON BLAKE PRICE: Surface-Eroding Drug Delivery Films for Sequential and/or

Intermittent Release of Psychoactive Drugs For patients with psychiatric diseases, adherence to medication schedules, medication

errors, and abuse are common issues. Promising new forms of therapy for these patients, such as micro-dosed lysergic acid diethylamide (LSD), where patients receive 10-20% of a full dose every third day, present further drug delivery challenges. Sequential or intermittent release of drugs from an implanted device could ensure long-term drug compliance, automate drug dosing during the life of the implant, and eliminate potential for abuse and medication errors. To this end, we generated …

Sol Retractor: Rapidly Deployable Film-Based C-Section Retractor, Casey Lee, Silas Cleveland, Jose Dolores Valdivieso, Joseph Perks

Honors Theses

Cesarean Sections (C-sections), a surgery conducted for baby delivery, can be divided into four distinct categories; Category 1 and 2 are considered emergency c-sections, and Category 3 and 4 are scheduled c-sections [2]. A comparative study from 2016 analyzed the difference of need for postoperative treatment between the Collins or the Alexis O retractor ( n = 100). The Alexis O C-Section retractor resulted in 19% of women requiring postoperative treatment, including medication, monitoring, and an extended stay at the hospital. The Collins resulted in 43% of the patients requiring postoperative treatment (p = 0.001) [5]. In emergency C-sections, surgical …

A Novel Device To Remove Kidney Stone Fragments From The Ureter, Madeline Feinberg, Christina Pavlovsky, John Kasel

Honors Theses

Every year kidney stones affect 654,000 Americans and 25% of these cases require a ureteroscopy which is performed on patients with kidney stones greater than 4 mm in the ureter. A holmium laser is used to rupture the kidney stone resulting in fragmentation of the stone. If not removed, these residual fragments can cause pain and may require a secondary procedure to remove them. The most common method for removing stone fragments is inserting a basket device through a port on the ureteroscope, encapsulating individual stone fragments, and manually removing the device. This device requires multiple insertions to remove the …

Breathe Easy: A More Efficient Way To Avoid Tracheostomy Airway Blockages, Olivia Zimmerman, Kathleen Swanson, Katelynn Russ

Honors Theses

ZIMMERMAN, OLIVIA Breathe Easy: A More Efficient Way to Avoid Tracheostomy Airway Blockages

Department of Biomedical Engineering, June 2020.

ADVISOR: Professor Cotter and Professor Khetan

A Revolutionary Approach To Transsphenoidal Surgery: The Pedg, Paidamoyo Ewing, Lavonia Duncan, Giselle Perkowski, Erendira Garcia Pallares

Honors Theses

Approximately 1500 pituitary tumors diagnosed each year are tough textured microadenomas found mainly in patients aging from 55-80 [1]. Tough textured tumors in the pituitary gland can cause hormonal imbalances and vision changes. For our Capstone Project, we focused on designing an endonasal device, the Pituitary Endonasal Deep Grasper (PEDG), that improves the efficiency of tough textured pituitary tumor removal by improving upon various mechanisms in Transsphenoidal Surgery including rotation, tip grasping, suction, and handle control. Our device contains a comfortable handle that allows for better control and precision during the procedure. We designed a grasping mechanism that is strong …

Breathe Easy: A More Efficient Way To Avoid Tracheostomy Airway Blockages, Katelynn Russ, Kathleen Swanson, Olivia Zimmerman

Honors Theses

Over 100,000 people receive tracheostomies each year in the United States when mechanical ventilation is needed for longer than 48 hours, a patient has a chronically obstructed airway, or the patient is unable to protect their airway from aspiration. A tracheostomy is inserted into a patient’s trachea in order to modify their airway through a tracheotomy procedure. A tracheostomy tube alters the natural lining of an airway which normally has a 5-50 μm thick layer of mucus. An airway with a tracheostomy tube produces more mucus than the average airway of a healthy person, and it also limits the patient’s …

Breathe Easy: A More Efficient Way To Avoid Tracheostomy Airway Blockages, Kathleen Swanson, Katelynn Russ, Olivia Zimmerman

Honors Theses

Over 100,000 people receive tracheostomies each year in the United States when mechanical ventilation is needed for longer than 48 hours, a patient has a chronically obstructed airway, or the patient is unable to protect their airway from aspiration. A tracheostomy is inserted into a patient’s trachea in order to modify their airway through a tracheotomy procedure. A tracheostomy tube alters the natural lining of an airway which normally has a 5-50 μm thick layer of mucus. An airway with a tracheostomy tube produces more mucus than the average airway of a healthy person, and it also limits the patient’s …

An Improved Method For Hospital Acquired Pressure Ulcer (Hapu) Prevention, Megan Morrissey, Jillian Yeager, Julia Beekman

Honors Theses

Hospital acquired pressure ulcers (HAPUs), also called bedsores, are damage to the skin and/or underlying tissue caused by prolonged pressure on the bony areas of the body, with around 20% of pressure ulcers occurring in the heel region. Currently, the most common practice for HAPU prevention is arbitrary manual repositioning of patients by nurses every 1-2 hours. The goal of our project was to address HAPUs in the heel region of low mobility patients through an ulceration risk sensing system. Our team has created a wearable ulceration risk assessment system that combines individual patient risk data with real time pressure …

Redesigned Endoscopic Bite Block For Geriatric Patients, Kayla Fisher, Katherine Gregory, Owen Corey

Honors Theses

Esophagogastroduodenoscopy (EGD) is an examination of the interior of the esophagus, stomach, and beginning of the small intestine. Upper gastrointestinal (GI) endoscopies are used to diagnose ulcers, cancers, and gastrointestinal tract diseases, as well as to collect biopsy samples. In 2008, over 55 million procedures were performed with GI endoscopic devices [1]. In order to keep the mouth propped open during this procedure, a bite block is used. This bite block ensures that the patient will not bite down on the endoscope during the procedure. Geriatric patients are more likely to have poor dental health due to medications they take, …

Heel Down And Toe-Off Time Measured With Ultrasonic Doppler System And Force Plate Sensor, Sabin Timsina

Honors Theses

Collie Box is a medical device that measures the gait parameters of the person walk- ing in front of it. This device uses the Ultrasonic Doppler system to extract the heel-contact and toe-off times of a person walking within the range of 2-10 meters. These times are used to determine the leg’s swing phase and double stance times. The ultrasonic transducer of 10mm diameter is driven at 40kHz. At the time of the heel-contact and toe-off, foot velocity is zero while the torso part of the human body is still in motion. The wide directivity of 10mm diameter ultrasonic transducer …

Designing An Antibiotic Eluting Trauma Screw To Reduce Short Term Infection In Bone Fractures, Dominic Lincoln

Honors Theses

Orthopedic infection in the United States is one of the most common and severe health risks faced by trauma patients. The most prevalent infection is orthopedic and trauma device-related infection (ORDI) and often occurs in long bones at the fracture site. The purpose of this paper is to explore this infection, its causes, and solutions currently on the market while providing novel solutions to the problem. The designs proposed will be evaluated for their effectiveness and value, while attempting to keep costs low for all stakeholders. The feasibility of patenting these ideas will also be considered, as will the testing …

Applying An Innovative Idea To Kidney Stone Removal, Jack Beaty

Honors Theses

Renal lithiasis, commonly referred to as “kidney stones” is a condition in which the urine composition crystallizes and cannot pass through the ureter, causing pain and discomfort. Renal lithiasis can be caused by diet, infection, reduced water retention, or hereditary disorders; each of which results in a distinct stone composition [1]. Stone compositions can vary between calcium oxalate, struvite, uric acid, and cystine[2]. Each stone type, however, provides the same pain to the patient and the same potential risk of blocking the urinary system.

Kidney stone symptoms may include but are not limited to: pain in the lower back, the …

The Theia Soteria: Alternative Design For Safer Initial Entry During Laparoscopic Procedures, Kayla Dubois, Patrick Ryan, Madelyn Joanis

Honors Theses

Laparoscopic procedures account for 15 million surgeries worldwide [1], with the initial entry into the peritoneal cavity accounting for 33-50% of all major laparoscopic complications [7]. This initial entry is the most dangerous as surgeons must enter the cavity using a sharp object with no visibility and space between the outer surface of the cavity and internal tissues. During the initial entry into the peritoneal cavity, the patients undergoing laparoscopic procedures are at a high risk for damage to internal organs and vasculature, necessitating the development of a device to protect these internal tissues and increase patient safety.

Cuffed Pediatric Endotracheal Tubes, Jennifer Nutter, Emmanuela Oppong, Colleen Pouliot

Honors Theses

Endotracheal tubes (ET) are used to provide patients with an adequate airway when they are unable to breathe on their own. ET tubes can be used in emergency situations, surgical procedures, and on-floor intubations. The two main types of ET tubes are cuffed and uncuffed. Due to the fragile structure of a child's throat, uncuffed tubes are primarily used in pediatric patients. Uncuffed tubes can slip out of place resulting in air leakage and improper oxygenation. In contrast, cuffed ET tubes provide a proper seal to the airway and prevent against aspiration. The following work proposes an improved design for …

A Strategic Audit Of Medtronic Plc, Jozzy Carter

Honors Theses

Humans will always have a need for healthcare, and as the world continues to innovate in the tech space, consumers will demand advances in medicine and medical devices. Medtronic is at the forefront of this innovation but faces intense competition in the medical technologies industry. This poses the question: what can Medtronic do to continue its growth and stay competitive in this space? This paper offers an analysis of Medtronic as a medical device company by offering insight to its competitive advantage, financials, business mix, and value chain. It also analyzes the forces that affect Medtronic using SWOT, PEST, and …

Subtalar Fusion Fixture Design And Test, Nathan Ortiz

Honors Theses

Subtalar arthrodesis is performed when cartilage in the talo-calcaneal (the ankle) joint is degraded in a patient and there are multiple approaches to this surgery. Using synthetic bone material, fixtures were cast from aluminum, using the process of evaporation pattern casting, and epoxy. This casting was used to grip the calcaneus bone of the foot in order to load it mechanically, simulating different scenarios that would be encountered during walking. The relative displacement of the ankle joint was measured using a digital image correlation (DIC) program that was modified to work in both two- and three-dimensional space. This program can …