Engineering Commons^™

Breast Cancer Risk In Women With Breast Bilateral Asymmetry: Machine Learning Based Risk Analysis And Mitigation Through Developing A Framework For Customized Bra Design, Xi Feng

Electronic Thesis and Dissertation Repository

Breast cancer is the most prevalent form of cancer globally, accounting for 12.5% of all new cases annually. Research has found a significant correlation between breast bilateral asymmetry and an increased risk of cancer, with women diagnosed with breast cancer having higher levels of bilateral asymmetrical breast volume. Unfortunately, 87% of women with breast asymmetry lack adequate tools for assessing their cancer risk. Early screening using bilateral asymmetry to predict a woman's long-term risk of breast cancer can help physicians make informed decisions about whether to recommend sequential imaging and the frequency of screening. Another important factor in understanding the …

Machine Learning Classifiers For Chronic Obstructive Pulmonary Disease Assessment Using Lung Ct Data., Halimah Alsurayhi

Electronic Thesis and Dissertation Repository

Chronic Obstructive Pulmonary Disease (COPD) is a condition characterized by persistent inflammation and airflow blockages in the lungs, contributing to a significant number of deaths globally each year. To guide tailored treatment strategies and mitigate future risks, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) employs a multifaceted assessment system of COPD severity, considering patient's lung function, symptoms, and exacerbation history. COPD staging systems, such as the high-resolution eight-stage COPD system and the GOLD 2023 three staging systems, have been later developed based on these factors. Lung Computed Tomography (CT) is becoming increasingly crucial in investigating COPD as it …

Development Of A Cost-Constrained Intelligent Prosthetic Knee With Real-Time Machine Learning, Predictive Stumble Control, Lucas Jonathan Galey

Open Access Theses & Dissertations

The field of biomechatronics is evolving quickly with advances in computer science, biology, and electrical and mechanical engineering. Coupled with increased interests in machine learning (ML) across all industry sectors, there are opportunities to leverage advanced analytics in uniquely complex problems. This study aimed to deploy real-time ML predictions in a novel microprocessor-controlled prosthetic knee (MPK) device capable of identifying and responding to stumble-events to reduce amputee fall prevalence. Innately, stumbling is a chaotic event. Current MPKs operate by detecting gait characteristics and reacting to preprogrammed states. While these systems are beneficial in significant ways, such as energy expenditure and …

Machine Learning For Biosensors, Gayathri Anapanani

Graduate Theses, Dissertations, and Problem Reports

Biosensors have become increasingly popular as diagnostic tools due to their ability to detect and quantify biological analytes in a wide range of applications. With the growing demand for faster and more reliable biosensing devices, machine learning has become a valuable tool in enhancing biosensor performance. In this report, we review recent progress in the application of machine learning to biosensors. We discuss the potential benefits of using machine learning in biosensors, including improved sensitivity, selectivity, and accuracy. We also discuss the various machine learning techniques that have been applied to biosensors, including data preprocessing, feature extraction, and classification and …

Predicting The Progression Of Diabetes Mellitus Using Dynamic Plantar Pressure Parameters, Mathew Sunil Varre

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Diabetic peripheral neuropathy is one of the common complications of type-2 diabetes mellitus (DM). Changes in the intrinsic plantar tissue coupled with repetitive mechanical loads and loss of sensation may lead to foot related complications (skin break down, ulcerations, and amputations) in persons with neuropathy if left untreated. The purpose of this dissertation was to stratify individuals with pre-diabetes, diabetes with and without neuropathy using dynamic plantar pressure parameters during walking, using machine learning algorithms.Methods: Plantar pressure data was collected from one hundred participants during walking with pressure measuring insoles fixed between the feet and thin socks. Simultaneously high-definition …

The Bracelet: An American Sign Language (Asl) Interpreting Wearable Device, Samuel Aba, Ahmadre Darrisaw, Pei Lin, Thomas Leonard

Chancellor’s Honors Program Projects

No abstract provided.

Automated Segmentation Of The Inner Ear And Round Window In Computed Tomography Scans Using Convolutional Neural Networks, Kyle A. Rioux

Electronic Thesis and Dissertation Repository

Computed tomography (CT) scans are acquired prior to cochlear implant (CI) surgery. Three-dimensional segmentations of the inner ear (IE) and round window (RW) based on clinical CTs can improve the CI procedure. Software pipelines are presented here which employ convolutional neural networks to automatically segment the IE and RW. The first pipeline produces high resolution segmentations of the IE and RW in tightly cropped CTs. Mean IE Dice score and RW centroid error were 0.88, 0.57mm and 0.93, 0.18mm in implanted and non-implanted samples, respectively. The second pipeline automatically segments the IE in large field of view CTs of any …

Classifying Electrocardiogram With Machine Learning Techniques, Hillal Jarrar

Master's Theses

Classifying the electrocardiogram is of clinical importance because classification can be used to diagnose patients with cardiac arrhythmias. Many industries utilize machine learning techniques that consist of feature extraction methods followed by Naive- Bayesian classification in order to detect faults within machinery. Machine learning techniques that analyze vibrational machine data in a mechanical application may be used to analyze electrical data in a physiological application. Three of the most common feature extraction methods used to prepare machine vibration data for Naive-Bayesian classification are the Fourier transform, the Hilbert transform, and the Wavelet Packet transform. Each machine learning technique consists of …

Statistical Machine Learning For Breast Cancer Detection With Terahertz Imaging, Tanny Andrea Chavez Esparza

Graduate Theses and Dissertations

Breast conserving surgery (BCS) is a common breast cancer treatment option, in which the cancerous tissue is excised while leaving most of the healthy breast tissue intact. The lack of in-situ margin evaluation unfortunately results in a re-excision rate of 20-30% for this type of procedure. This study aims to design statistical and machine learning segmentation algorithms for the detection of breast cancer in BCS by using terahertz (THz) imaging. Given the material characterization properties of the non-ionizing radiation in the THz range, we intend to employ the responses from the THz system to identify healthy and cancerous breast tissue …

Novel Machine Learning And Wearable Sensor Based Solutions For Smart Healthcare Monitoring, Rajdeep Kumar Nath

Theses and Dissertations--Electrical and Computer Engineering

The advent of IoT has enabled the design of connected and integrated smart health monitoring systems. These health monitoring systems can be utilized for monitoring the mental and physical wellbeing of a person. Stress, anxiety, and hypertension are the major elements responsible for the plethora of physical and mental illnesses. In this context, the older population demands special attention because of the several age-related complications that exacerbate the effects of stress, anxiety, and hypertension. Monitoring stress, anxiety, and blood pressure regularly can prevent long-term damage by initiating necessary intervention or clinical treatment beforehand. This will improve the quality of life …

Intraoperative Localization Of Subthalamic Nucleus During Deep Brain Stimulation Surgery Using Machine Learning Algorithms, Mahsa Khosravi

Electronic Thesis and Dissertation Repository

This thesis presents a novel technique for localizing the Subthalamic Nucleus (STN) during Deep Brain Stimulation (DBS) surgery. DBS is an accepted treatment for individuals living with Parkinson's Disease (PD). This surgery involves implantation of a permanent electrode inside the STN to deliver electrical current. The STN is a small grey matter structure within the brain, which makes accurate placement a challenging task for the surgical team. Prior to placement of the permanent electrode, intraoperative microelectrode recordings (MERs) of neural activity are used to localize the STN. The placement of the permanent electrode and the success of the stimulation therapy …

Computer-Aided Classification Of Impulse Oscillometric Measures Of Respiratory Small Airways Function In Children, Nancy Selene Avila

Open Access Theses & Dissertations

Computer-aided classification of respiratory small airways dysfunction is not an easy task. There is a need to develop more robust classifiers, specifically for children as the classification studies performed to date have the following limitations: 1) they include features derived from tests that are not suitable for children and 2) they cannot distinguish between mild and severe small airway dysfunction.

This Dissertation describes the classification algorithms with high discriminative capacity to distinguish different levels of respiratory small airways function in children (Asthma, Small Airways Impairment, Possible Small Airways Impairment, and Normal lung function). This ability came from innovative feature selection, …

Estimation Of Multi-Directional Ankle Impedance As A Function Of Lower Extremity Muscle Activation, Lauren Knop

Dissertations, Master's Theses and Master's Reports

The purpose of this research is to investigate the relationship between the mechanical impedance of the human ankle and the corresponding lower extremity muscle activity. Three experimental studies were performed to measure the ankle impedance about multiple degrees of freedom (DOF), while the ankle was subjected to different loading conditions and different levels of muscle activity. The first study determined the non-loaded ankle impedance in the sagittal, frontal, and transverse anatomical planes while the ankle was suspended above the ground. The subjects actively co-contracted their agonist and antagonistic muscles to various levels, measured using electromyography (EMG). An Artificial Neural Network …

Relation Prediction Over Biomedical Knowledge Bases For Drug Repositioning, Mehmet Bakal

Theses and Dissertations--Computer Science

Identifying new potential treatment options for medical conditions that cause human disease burden is a central task of biomedical research. Since all candidate drugs cannot be tested with animal and clinical trials, in vitro approaches are first attempted to identify promising candidates. Likewise, identifying other essential relations (e.g., causation, prevention) between biomedical entities is also critical to understand biomedical processes. Hence, it is crucial to develop automated relation prediction systems that can yield plausible biomedical relations to expedite the discovery process. In this dissertation, we demonstrate three approaches to predict treatment relations between biomedical entities for the drug repositioning task …