Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Engineering
Stabilization Of Extended Diffuse Optical Spectroscopy Measurements On In Vivo Human Skeletal Muscle During Dynamic Exercise, Brad A. Henry
Stabilization Of Extended Diffuse Optical Spectroscopy Measurements On In Vivo Human Skeletal Muscle During Dynamic Exercise, Brad A. Henry
Theses and Dissertations--Biomedical Engineering
This research investigates various applications of diffuse correlation spectroscopy (DCS) on in-vivo human muscle tissue, both at rest and during dynamic exercise. Previously suspected muscle tissue relative blood flow (rBF) baseline shift during extended measurement with DCS and DCS-Near infrared spectroscopy (NIRS) hybrid optical systems are verified, quantified, and resolved by redesign of optical probe and alteration in optical probe attachment methodology during 40 minute supine bed rest baseline measurements. We then translate previously developed occlusion techniques, whereby rBF and relative oxygen consumption rV̇O2 are calibrated to initial resting absolute values by use of a venous occlusion (VO) and …
Use Of Hybrid Diffuse Optical Spectroscopies In Continuous Monitoring Of Blood Flow, Blood Oxygenation, And Oxygen Consumption Rate In Exercising Skeletal Muscle, Katelyn Gurley
Theses and Dissertations--Biomedical Engineering
This study combines noninvasive hybrid diffuse optical spectroscopies [near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS)] with occlusive calibration for continuous measurement of absolute blood flow (BF), tissue blood oxygenation (StO2), and oxygen consumption rate (VO2) in exercising skeletal muscle. Subjects performed rhythmic dynamic handgrip exercise, while an optical probe connected to a hybrid NIRS/DCS flow-oximeter directly monitored oxy-, deoxy-, and total hemoglobin concentrations ([HbO2], [Hb], and [tHb]), StO2, relative BF (rBF), and relative VO2 (rVO2) in the forearm flexor muscles. Absolute baseline BF and …