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Health and Physical Education Commons™
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Full-Text Articles in Health and Physical Education
Sympathoinhibition And Vasodilation Contribute To The Acute Hypotensive Response Of The Superoxide Dismutase Mimic, Mntnbuoe-2-Pyp5+, In Hypertensive Animals, Sarah L. Schlichte, Elizabeth J. Pekas, Taylor J. Bruett, Elizabeth A. Kosmacek, Bryan T. Hackfort, Jordan M. Rasmussen, Kaushik P. Patel, Song-Young Park, Rebecca E. Oberley-Deegan, Matthew C. Zimmerman
Sympathoinhibition And Vasodilation Contribute To The Acute Hypotensive Response Of The Superoxide Dismutase Mimic, Mntnbuoe-2-Pyp5+, In Hypertensive Animals, Sarah L. Schlichte, Elizabeth J. Pekas, Taylor J. Bruett, Elizabeth A. Kosmacek, Bryan T. Hackfort, Jordan M. Rasmussen, Kaushik P. Patel, Song-Young Park, Rebecca E. Oberley-Deegan, Matthew C. Zimmerman
Health and Kinesiology Faculty Publications
The pathogenesis of hypertension has been linked to excessive levels of reactive oxygen species (ROS), particularly superoxide (O2•−), in multiple tissues and organ systems. Overexpression of superoxide dismutase (SOD) to scavenge O2•− has been shown to decrease blood pressure in hypertensive animals. We have previously shown that MnTnBuOE-2-PyP5+ (BuOE), a manganese porphyrin SOD mimic currently in clinical trials as a normal tissue protector for cancer patients undergoing radiation therapy, can scavenge O2•− and acutely decrease normotensive blood pressures. Herein, we hypothesized that BuOE decreases hypertensive blood pressures. Using angiotensin II (AngII)-hypertensive mice, we demonstrate that BuOE administered both intraperitoneally and …
Fit For Fire: A 10-Week Low-Cost Hift Experiential Learning Initiative Between Underrepresented Kinesiology Undergraduates And Hypertensive Deconditioned Firefighters Improves Their Health And Fitness, Melanie Poudevigne, Christina Day, Eon Campbell, Da’Lynn Mills, Reginald Porter, Ximena Zornosa, Thomas Andre
Fit For Fire: A 10-Week Low-Cost Hift Experiential Learning Initiative Between Underrepresented Kinesiology Undergraduates And Hypertensive Deconditioned Firefighters Improves Their Health And Fitness, Melanie Poudevigne, Christina Day, Eon Campbell, Da’Lynn Mills, Reginald Porter, Ximena Zornosa, Thomas Andre
Faculty and Student Publications
The aims of this study were to investigate the feasibility of an experiential learning initiative led by minority exercise science undergraduates and to observe the adaptations after a 10-week high-intensity functional training (HIFT) program in 34 underrepresented, hypertensive, and overweight/obese professional firefighters (PFF; age: 36.8 ± 11.0 years, body weight: 97.3 ± 21.5 kg, height: 181.7 ± 6.6 cm; BMI: 29.2 ± 4.9 kg/m2). Data were analyzed for muscular strength and endurance, cardiorespiratory endurance, body composition, agility, flexibility, and readiness for change. The PFFs trained two to three times weekly during their work shifts at vigorous intensity for 40 min. …