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Resistance Exercise Elicits Selective Mobilization And Adhesion Characteristics Of Granulocytes And Monocyte Subsets, Adam Jajtner
Resistance Exercise Elicits Selective Mobilization And Adhesion Characteristics Of Granulocytes And Monocyte Subsets, Adam Jajtner
Electronic Theses and Dissertations
Resistance exercise eliciting muscle damage results in an immune response, leading to increases in circulating cytokines, and immune cell mobilization. Classical monocytes respond to muscle damage, however, little is known about the intermediate or nonclassical monocyte response to resistance exercise. Moreover, the impact of polyphenol supplementation in conjunction with resistance exercise on the innate immune response is unknown. The purpose of this study was to examine the immune response following resistance exercise with (PPB) and without (PL) polyphenol supplementation. Thirty-nine untrained men were randomized into three groups: PPB (n=13, 21.8±2.5yrs, 171.2±5.5cm, 71.2±8.2kg), PL (n=15, 21.6±2.5yrs, 176.5±4.9cm, 84.0±15.7kg) or a control …
Intramuscular Tnf-Alpha Signaling In Response To Resistance Exercise And Recovery In Untrained Males., Jeremy Townsend
Intramuscular Tnf-Alpha Signaling In Response To Resistance Exercise And Recovery In Untrained Males., Jeremy Townsend
Electronic Theses and Dissertations
INTRODUCTION: The nuclear factor kappa B (NF-κβ) signaling cascade is responsible for mediating stress-activated catabolic effects of Tumor Necrosis Factor Alpha (TNF-α) downstream of the TNF receptor (TNFR1). NF-κβ transcription factor remains inhibited in the cytosol of the muscle and can be stimulated for translocation and transcription by a variety of external stimuli, most notably by pro-inflammatory cytokines and oxidative stress. Nevertheless, currently there is a gap in the literature with regard to the time course effect of NF-κβ signaling following acute resistance exercise in humans. PURPOSE: To observe the effects of an acute lower-body resistance exercise protocol and subsequent …