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Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz
Effects Of Aging On Post-Exercise Oxygen Consumption: A Preliminary Study, Steven Klepacz
Health, Exercise, and Sports Sciences ETDs
Aging and excess post-exercise oxygen consumption (EPOC) is something that has not been adequately studied. Studies looking at EPOC mostly are compiled of young college age individuals. Aging in humans is a topic of much research with still more to be learned. The study in this paper attempts to answer the question of whether age affects EPOC when performing a certain exercise. Preliminary findings based on general age-related research suggest the possibility. This thesis will explore the current research related to age and EPOC, analyze the findings, and discuss additional avenues for future research.
The Effect Of Acute Aerobic Exercise And Rapamycin Treatment On Autophagy And The Heat Shock Response In Peripheral Blood Mononuclear Cells Of Prediabetics, James Jermey Mccormick
The Effect Of Acute Aerobic Exercise And Rapamycin Treatment On Autophagy And The Heat Shock Response In Peripheral Blood Mononuclear Cells Of Prediabetics, James Jermey Mccormick
Health, Exercise, and Sports Sciences ETDs
Objectives: Recently, a malfunction of the autophagic pathway has been implicated with impaired glucose metabolism and progression from prediabetes to type 2 diabetes. Further, an interconnection has been suggested between the autophagy and heat shock protein (HSP) systems. The aims of the present study were to investigate the effects of exercise and rapamycin treatment (RAPA) on the autophagic process and HSP in peripheral blood mononuclear cells (PBMCs) from prediabetics compared to controls. Methods: Two groups matched for age and sex served as subjects and consisted of six prediabetic (42.4±11.7) and six controls (44.4±11.9). Subjects exercised at 50% of VO2max for …
Coordination Between Autophagy And The Heat Shock Response: Evidence From Exercise In Animals And Humans, Nathan H. Cole
Coordination Between Autophagy And The Heat Shock Response: Evidence From Exercise In Animals And Humans, Nathan H. Cole
Health, Exercise, and Sports Sciences ETDs
Proteins play a critical role in nearly every biological activity. In consequence, organismal health and homeostasis often hinges on the ability of intracellular regulatory systems to sustain the quality and function of these diverse, structurally complex macromolecules. Correct protein function depends on correct form, and during periods of destabilizing cellular stress, protein quality is managed in part by the heat shock response, which acts to support, isolate, and reform new or damaged proteins, and in part by the autophagic recycling of abnormal proteins, cytotoxic protein aggregates, and terminally damaged organelles. We conducted a pooled analysis of available research in humans …