Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 5 of 5
Full-Text Articles in Education
Designing Assessment Tasks For Deep Thinking, Gabrielle Matters
Designing Assessment Tasks For Deep Thinking, Gabrielle Matters
Dr Gabrielle Matters
I want to present some ideas about how a valid and reliable process for assessing deep thinking is not a function of the assessment regime (such as external or internal, standardised or teacher-devised), but is actually a product of the successful application of certain design criteria and the interplay of three essential elements. The argument I present rests on one simple belief that I hold: the capacity to design good assessment tasks is a vital part of an extensive professional repertoire and, as such, demands space and time, ritual and respect. (Teacher–assessors should not let anybody tell them that designing …
Perceived Impact Of Curriculum Management Audit Recommendations On Increased Student Achievement (Dissertation), Kelly Cross
Perceived Impact Of Curriculum Management Audit Recommendations On Increased Student Achievement (Dissertation), Kelly Cross
Kelly L. Cross
Curriculum management audits are an intensive investigation, or audit, of a school district's daily operations, including curriculum, policies, organizational structure, financial operations, and use of assessment data. Curriculum audits are conducted by a team of certified auditors composed of professional educators and administrators. Curriculum audit findings are used to generate recommendations, which are presented to the school district in an audit report. The audit recommendations provide the district with specific recommended actions that are intended to improve district operations and to improve student achievement. This research examined whether implementation of curriculum audit recommendations, as perceived by key administrators, influenced student …
Solving The Multilevel Dilemma, Bradley Baurain
Changes In Calcineurin Expression Induced In The Rat Brain By The Administration Of Antipsychotics, W. Rushlow, Y. Seah, Daniel Belliveau, N. Rajakumar
Changes In Calcineurin Expression Induced In The Rat Brain By The Administration Of Antipsychotics, W. Rushlow, Y. Seah, Daniel Belliveau, N. Rajakumar
Daniel J. Belliveau
Calcineurin (CN) was recently identified as a susceptibility gene for schizophrenia as well as showing altered RNA expression levels in the post-mortem brains of individuals with schizophrenia. CN knockout mice show a number of behaviours associated with schizophrenia, including deficits in sensorimotor gating, suggesting a link between CN and psychosis. Concurrently, we found, using genome screening techniques, that antipsychotics alter CN expression levels. Therefore, western blotting, in situ hybridization, immunocytochemistry and phosphatase assays were employed to determine what effect antipsychotics have on CN. The results indicate that clozapine, risperidone and haloperidol cause substantial reductions in the A subunit of CN …
Nerve Growth Factor Increases Connexin43 Phosphorylation And Gap Junctional Intercellular Communication, P. Cushing, R. Bhalla, A. Johnson, W. Rushlow, S. Meakin, Daniel Belliveau
Nerve Growth Factor Increases Connexin43 Phosphorylation And Gap Junctional Intercellular Communication, P. Cushing, R. Bhalla, A. Johnson, W. Rushlow, S. Meakin, Daniel Belliveau
Daniel J. Belliveau
The function of gap junctions is regulated by the phosphorylation state of their connexin subunits. Numerous growth factors are known to regulate connexin phosphorylation; however, the effect of nerve growth factor on gap junction function is not understood. The phosphorylation of connexin subunits is a key event during many aspects of the lifecycle of a connexin, including open/close states, assembly/trafficking, and degradation, and thus affects the functionality of the channel. PC12 cells infected with connexin43 (Cx43) retrovirus were used as a neuronal model to characterize the signal transduction pathways activated by nerve growth factor (NGF) that potentially affect the functional …