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Articles 1 - 4 of 4
Full-Text Articles in Philosophy of Science
Transdisciplinary Environmental Work: An Evaluation Of Transdisciplinarity In The Field Of Environmental Science And Its Relevance To South Carolina Conservation Efforts In Lake Wateree And The Catawba Indian Reservation, Olivia Mn Shugart
Senior Theses
Transdisciplinarity describes the integration of knowledge and exchange of ideas across diverse academic disciplines, public stakeholders, and decision-makers. In this paper, I discuss the relevance of transdisciplinarity to the environmental field and offer ways in which its principles could be employed to enhance current South Carolina conservation efforts. I advocate for transdisciplinary work through analyzing existing discourse on the value of transdisciplinary research to the environmental field, and I present some of the challenges associated with this mass integration of knowledge. Finally, I describe three models of transdisciplinary research that have been proposed by scholars to address some of these …
The Vector Of Scientific Disciplinarity: An Exploration Of Scientific Disciplines And The Future Of Interdisciplinary Research, Emma K. Garrison
The Vector Of Scientific Disciplinarity: An Exploration Of Scientific Disciplines And The Future Of Interdisciplinary Research, Emma K. Garrison
Senior Theses
The disciplinarity of science and the future of interdisciplinarity in science is deeply connected with understanding the scope of scientific practice as well as the demarcation and organization of scientific disciplines. These topics, explored through the structure of their subjects, theories, methods, and interpretation, lead to the conclusion that science and its disciplines are largely defined by the integration of philosophical principles into the ethos of the practices rather than by any specific criteria. The ways in which different disciplines behave and interpret philosophies impact how those disciplines are organized and categorized, resulting in deep philosophical and perspective divides between …
Non-Empirical Modelling And Theorizing: Scientific Progress In Particle Physics, Cristin Cain Chall
Non-Empirical Modelling And Theorizing: Scientific Progress In Particle Physics, Cristin Cain Chall
Theses and Dissertations
Particle physics (and other fundamental physics research, including searches for a theory of quantum gravity) faces a problem when it comes to acquiring experimental evidence. Many theories and models make predictions that cannot be tested with current, or even prospective technology. Yet these fields continue to develop, with new models and theories regularly being introduced, scrutinized, changed, and discarded. My project aims at examining the way theories and models are constructed, adapted, and assessed in fields that lack the empirical evidence that usually grounds such tasks. I will focus on two prominent examples: string theory and attempts to explain electroweak …
Tumor Suppressor Mir-489 Regulates Proliferation, Autophagy And Overcomes Drug-Resistance In Breast Cancer, Mithil Soni
Tumor Suppressor Mir-489 Regulates Proliferation, Autophagy And Overcomes Drug-Resistance In Breast Cancer, Mithil Soni
Theses and Dissertations
Despite decades of extensive research, breast cancer remains an untamable disease due to complexity and heterogeneity of disease. It is for this very reason, most efforts targeting a single pathway did not yield satisfactory results. Discovery of a novel therapeutic agents targeting multiple pathways, such as miRNAs, holds promise for future cancer therapy. This study was aimed to explore therapeutic potential of one such microRNA, miR-489. In the first study, we identified autophagy as a novel pathway targeted by miR-489 and reported ULK1 and LAPTM4B to be a direct of miR-489 target. We showed that miR-489 mediated autophagy inhibition and …