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Full-Text Articles in Arts and Humanities
Examining The Evolution Of Phosphagen Kinases: A Study Of A Dimeric Arginine Kinase From Sea Urchin (Strongylocentrotus Purpuratus) Eggs, Brenda Christine Held
Examining The Evolution Of Phosphagen Kinases: A Study Of A Dimeric Arginine Kinase From Sea Urchin (Strongylocentrotus Purpuratus) Eggs, Brenda Christine Held
USF Tampa Graduate Theses and Dissertations
The phosphagen kinases are a family of enzymes that catalyze the reversible phosphorylation of specific phosphagens using ATP as the phosphate donor. The evolutionary relationships between the enzymes in this family have been studied for over 30 years and yet aspects of the relationships remain unclear. Here, arginine kinase from Strongylocentrotus purpuratus eggs was purified to homogeneity and analyzed for physical and kinetic characteristics as well as its sequence homology with other phosphagen kinases. The results indicate that dimeric arginine kinase from S. purpuratus eggs evolved from a dimeric creatine kinase after dimeric creatine kinase evolved from a monomeric arginine …
The Bioinorganic Chemistry Of Copper-Containing Systems: From Type-3 Systems Pertinent To Alzheimer’S Disease To Mononuclear Hydrolysis Involved In Biological Development, Giordano Faustini Zimmerer Da Silva
The Bioinorganic Chemistry Of Copper-Containing Systems: From Type-3 Systems Pertinent To Alzheimer’S Disease To Mononuclear Hydrolysis Involved In Biological Development, Giordano Faustini Zimmerer Da Silva
USF Tampa Graduate Theses and Dissertations
Although transition metals are essential for life, misregulation of redox-active metal uptake, delivery, storage, and excretion has been linked with a series of neurodegenerative disorders. Alzheimer's disease (AD) is considered an epidemic and is the most widespread of all forms of dementia. Copper ions found in large concentrations localized in amyloid-ß plaques in the brain of AD patients have been linked with the generation of reactive oxygen species which are suspected to be the culprits leading to neuronal cell death. Herein a series of mechanistic and spectroscopic studies elucidate the chemistry about the metal-centered oxidation of biomolecules, including catecholamine neurotransmitters …
Investigation Of Zrni, Zrmn2 And Zn(Bh4)2 Metal/Complex Hydrides For Hydrogen Storage, Diego Escobar
Investigation Of Zrni, Zrmn2 And Zn(Bh4)2 Metal/Complex Hydrides For Hydrogen Storage, Diego Escobar
USF Tampa Graduate Theses and Dissertations
The demand for efficient and clean fuel alternatives has been increasing in recent years and is expected to become more pronounced in the future. Utilization of hydrogen as a fuel is one of the most promising energy resources due to its easy production, abundance, regeneration and not creation of greenhouse gases during its combustion. Although gaseous hydrogen has a very high energy content per unit weight, its volumetric energy density is rather low. The large scale use of hydrogen as a fuel crucially depends on the development of compact hydrogen storage materials with a high mass content of hydrogen relative …