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Articles 1 - 4 of 4
Full-Text Articles in Arts and Humanities
Statistical Estimation Of Physiologically-Based Pharmacokinetic Models: Identifiability, Variation, And Uncertainty With An Illustration Of Chronic Exposure To Dioxin And Dioxin-Like-Compounds., Zachary John Thompson
Statistical Estimation Of Physiologically-Based Pharmacokinetic Models: Identifiability, Variation, And Uncertainty With An Illustration Of Chronic Exposure To Dioxin And Dioxin-Like-Compounds., Zachary John Thompson
USF Tampa Graduate Theses and Dissertations
Assessment of human exposure to environmental chemicals is inherently subject to uncertainty and variability. There are data gaps concerning the inventory, source, duration, and intensity of exposure
as well as knowledge gaps regarding pharmacokinetics in general. These gaps result in uncertainties in exposure assessment.
The uncertainties compound further with variabilities due to population variations regarding stage of life, life style, and susceptibility,
etc. Use of physiologically-based pharmacokinetic (PBPK) models promises to reduce the uncertainties and enhance extrapolation between species, between routes, from high to low dose, and from acute to chronic exposure. However, fitting PBPK models is challenging because of …
Evaluation Of Repeated Biomarkers: Non-Parametric Comparison Of Areas Under The Receiver Operating Curve Between Correlated Groups Using An Optimal Weighting Scheme, Ping Xu
USF Tampa Graduate Theses and Dissertations
Receiver Operating Characteristic (ROC) curves are often used to evaluate the prognostic performance of a continuous biomarker. In a previous research, a non-parametric ROC approach was introduced to compare two biomarkers with repeated measurements. An asymptotically normal statistic, which contains the subject-specific weights, was developed to estimate the areas under the ROC curve of biomarkers. Although two weighting schemes were suggested to be optimal when the within subject correlation is 1 or 0 by the previous study, the universal optimal weight was not determined. We modify this asymptotical statistic to compare AUCs between two correlated groups and propose a solution …
Statistical Content In Middle Grades Mathematics Textbooks, Maria Consuelo (Suzie) Capiral Pickle
Statistical Content In Middle Grades Mathematics Textbooks, Maria Consuelo (Suzie) Capiral Pickle
USF Tampa Graduate Theses and Dissertations
Statistical Content in Middle Grades Mathematics Textbooks
Maria Consuelo (Suzie) Capiral Pickle
Abstract
This study analyzed the treatment and scope of
statistical concepts in four, widely-used, contemporary, middle
grades mathematics textbook series: Glencoe Math Connects,
Prentice Hall Mathematics, Connected Mathematics Project, and
University of Chicago School Mathematics Project. There were
three phases for the data analysis. Phase 1 addressed the location
and sequence of the statistical concepts. Phase 2 focused upon an
examination of the lesson narrative, its components and scope.
Phase 3 analyzed the level of cognitive demand required of the
students to complete the exercises, and the total …
Stochastic Modeling Of Network-Centric Epidemiological Processes, Divine Wanduku
Stochastic Modeling Of Network-Centric Epidemiological Processes, Divine Wanduku
USF Tampa Graduate Theses and Dissertations
The technological changes and educational expansion have created the heterogeneity in the human species. Clearly, this heterogeneity generates a structure in the population
dynamics, namely: citizen, permanent resident, visitor, and etc. Furthermore, as the heterogeneity in the population increases, the human mobility between meta-populations patches
also increases. Depending on spatial scales, a meta-population patch can be decomposed into sub-patches, for examples: homes, neighborhoods, towns, etc. The dynamics of human
mobility in a heterogeneous and scaled structured population is still its infancy level. We develop and investigate (1) an algorithmic two scale human mobility dynamic model for a meta-population. Moreover,the two …