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Articles 13681 - 13710 of 80949
Full-Text Articles in Entire DC Network
Uzbekistan Re-Emerges As The Strategic “Heartland Of The Heartland”, G. R. Copley
Uzbekistan Re-Emerges As The Strategic “Heartland Of The Heartland”, G. R. Copley
International Relations: Politics, Economics, Law
The article analyzes the influence of fundamental political and socio-economic changes in Uzbekistan on the formation of a new strategic situation in an important region of Eurasia. The emergence of a new, dynamically developing Uzbekistan, having a central position in Central Asia, can revive not only the region itself, but also the neighboring regions through which the Great Silk Road passed. Today, Uzbekistan has all the resources and opportunities to implement an ambitious reform program, as well as revitalize intra-regional cooperation in Central Asia. According to the author, Central Asia is still, and once again, the pivot of the “world …
Public Maladministration: The Ubiquitous Menace To Government Performance, Gerald E. Caiden, Naomi J. Caiden
Public Maladministration: The Ubiquitous Menace To Government Performance, Gerald E. Caiden, Naomi J. Caiden
Faculty Journal Articles
This essay, based on a lifetime’s research together around the world, focuses on the dark side of government: the wrongdoing of public officials that frustrate the efforts of humanity to better itself and to strive for perfection. It dwells on what goes needlessly wrong in public affairs - its failures and harmful actions, not its successes and achievements. All over the world people are increasingly upset with the performance of public authorities when misdeeds are hidden by confined blameworthy inner circles sworn to a secrecy enforced by public instruments, until they are eventually exposed to the public eye too late …
Vol. 1 Ch. 6 Soul Concepts Of Scioto Hopewell Communities: The Ontological Foundation Of Their Tripartite Ceremonial Alliance, Christopher Carr, Heather Smyth
Vol. 1 Ch. 6 Soul Concepts Of Scioto Hopewell Communities: The Ontological Foundation Of Their Tripartite Ceremonial Alliance, Christopher Carr, Heather Smyth
Encountering Hopewell in the Twenty-first Century, Ohio and Beyond
No abstract provided.
Vol. 2 Ch. 6 The Leake Site: Connecting The Southeast With The Hopewell Heartland, Scot Keith
Vol. 2 Ch. 6 The Leake Site: Connecting The Southeast With The Hopewell Heartland, Scot Keith
Encountering Hopewell in the Twenty-first Century, Ohio and Beyond
No abstract provided.
Protecting Against An Unable President: Reforms For Invoking The 25th Amendment And Overseeing Presidential Nuclear Launch Authority, Louis Cholden-Brown, Daisy De Wolff, Marcello Figueroa, Kathleen Mccullough
Protecting Against An Unable President: Reforms For Invoking The 25th Amendment And Overseeing Presidential Nuclear Launch Authority, Louis Cholden-Brown, Daisy De Wolff, Marcello Figueroa, Kathleen Mccullough
Reports
The immense powers of the presidency and the vast array of global threats demand a physically and mentally capable president. To help ensure able presidential leadership, this report advocates reforms related to the 25th Amendment, including proposals for an “other body” to act with the vice president in certain circumstances to declare the president unable and a mechanism for officials to report concerns about the president’s capacity. The report also recommends new checks on the president’s authority to use nuclear weapons, such as procedures for notifying top national security officials when use is contemplated.
This report was researched and written …
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Micheal Quennoz
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Micheal Quennoz
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
This report summarizes the results of a cultural resources survey by Gray & Pape, Inc., on behalf of their client, BIO-WEST, Inc., of six workspaces within four discontiguous locations along Big Creek in Fort Bend County, Texas totaling 6.1 hectares (15.1 acres) and approximately 1.5 kilometers (0.9 miles) in length. The Big Creek Channel Repair Project calls for bank stabilization efforts at each of the four locations. The goals of the survey were to determine if the proposed project would affect any previously identified archaeological sites as defined by Section 106 of the National Historic Preservation Act of 1966, as …
Cultural Resources Survey For The City Of Cleburne's Proposed Reuse Corridor Pipeline Johnson County, Texas, Garrett Wheaton
Cultural Resources Survey For The City Of Cleburne's Proposed Reuse Corridor Pipeline Johnson County, Texas, Garrett Wheaton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
In May 2020, AmaTerra Environmental, Inc. (AmaTerra) performed a cultural resources survey on behalf of The City of Cleburne Texas (City) and their engineering contractor Freese and Nichols Inc. (FNI), prior to the construction of a new reuse water line near Cleburne, Johnson County, Texas. The City is proposing to install five miles of reuse water line from the City’s wastewater treatment plant to the Nolan River at the northern end of Lake Pat Cleburne. As the City of Cleburne is a political subdivision of the State of Texas, it is subject to the Antiquities Code of Texas (ACT), requiring …
Intensive Cultural Resources Survey Of The 11.4-Acre Northwest Drive At Green Hill Road Tract, San Angelo, Tom Green County, Texas, Jesse O. Dalton, Jeffery D. Owens
Intensive Cultural Resources Survey Of The 11.4-Acre Northwest Drive At Green Hill Road Tract, San Angelo, Tom Green County, Texas, Jesse O. Dalton, Jeffery D. Owens
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by Mason Joseph Company, Inc. (Mason Joseph) to conduct a cultural resources survey and assessment for a proposed apartment complex development located on an approximately 4.6-hectare (11.4-acre) tract in San Angelo, Tom Green County, Texas. The proposed apartment complex would be located on undeveloped land in western San Angelo just northwest of the intersection of Northwest Drive and Green Hill Road. For the purposes of the cultural resources survey, the project area was assumed to consist of the entire 4.6-hectare (11.4-acre) tract.
The proposed undertaking would be sponsored by Mason Joseph, a private …
Archaeological Survey For The Lower Greens Bayou Trail Project, Segments Gr02 And Gr03, In Harris County, Texas, Michael Quennoz, Jacob Hilton, Amanda Kleopfer, Tony Scott
Archaeological Survey For The Lower Greens Bayou Trail Project, Segments Gr02 And Gr03, In Harris County, Texas, Michael Quennoz, Jacob Hilton, Amanda Kleopfer, Tony Scott
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Over several mobilizations between April 2018 and January 2020, Gray & Pape, Inc., of Houston, Texas, conducted an intensive pedestrian cultural resources survey of two segments (Segments GR02 and GR03) of proposed trail development along Lower Greens Bayou in the City of Houston, Harris County, Texas. The project alignment measures approximately 10.8 kilometers (6.7 miles) in length and encompasses approximately 9.6 hectares (23.7 acres) of area. Another 0.6 kilometers (0.4 miles) or 0.6 hectares (1.4 acres) of project alignment was removed from consideration. In total, approximately 11.4 kilometers (7.1 miles) or 10.2 hectares (25.1 acres) was surveyed for the project. …
Cultural Resources Survey For The Proposed Mud 121 Brazos River Levee Protection Project In Fort Bend County, Texas, Michael Quennoz, Tony Scott
Cultural Resources Survey For The Proposed Mud 121 Brazos River Levee Protection Project In Fort Bend County, Texas, Michael Quennoz, Tony Scott
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
This report summarizes the results of a cultural resources survey by Gray & Pape, Inc. of an approximately 14.8-hectare (36.6-acre) property in Fort Bend County, Texas, planned for a bank stabilization project on behalf of their client, Berg-Oliver Associates, Inc. The goals of the survey were to determine if the proposed project would affect any previously identified archaeological sites as defined by Section 106 of the National Historic Preservation Act of 1966, as amended (36 CFR 800), and to establish whether or not previously unidentified buried archaeological resources were located within the project’s Area of Potential Effect. Portions of the …
2018-2019 Annual Report Of Work Carried Out At Memorial Park, City Of Houston, Harris County, Texas, Michael Quennoz
2018-2019 Annual Report Of Work Carried Out At Memorial Park, City Of Houston, Harris County, Texas, Michael Quennoz
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
On behalf of the City of Houston and the Memorial Park Conservancy, Gray & Pape, Inc. conducted intensive pedestrian surveys of three areas totaling 144.4 hectares (357.6 acres) of Memorial Park, City of Houston, Harris County, Texas. Fieldwork was carried out between April 1, 2018 and March 31, 2019, under Texas Antiquities Annual Permit Number 8465. The following report presents the results of site file and background research, survey methods, field results, and conclusions and recommendations for each of these surveys. The goals of the intensive pedestrian surveys were to assist the Memorial Park Conservancy in identifying the presence of …
Intensive Cultural Resources Survey Of The Proposed West Fork Of The San Jacinto River South Drainage Channel Phase 3 Project, Montgomery County, Texas, Jeffrey D. Owens, Jesse O. Dalton
Intensive Cultural Resources Survey Of The Proposed West Fork Of The San Jacinto River South Drainage Channel Phase 3 Project, Montgomery County, Texas, Jeffrey D. Owens, Jesse O. Dalton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by LJA Engineering, Inc. (LJA), on behalf of Montgomery County Municipal Utility District (MUD) No. 157, to conduct a cultural resources inventory and assessment for the proposed West Fork of the San Jacinto River South Drainage Channel Phase 3 Project. The proposed undertaking would consist of constructing a new outfall structure within an approximately 1.5-hectare (3.6-acre) area on the eastern bank of the West Fork of the San Jacinto River near Moorhead Road. The project area is located on a broad coastal flat that has been historically mined for borrow materials, and numerous …
Intensive Cultural Resources Survey Of The Proposed City Of Conroe Stewarts Creek Wastewater System Improvements Project, Conroe, Montgomery County, Texas, Jeffrey D. Owens, Jesse O. Dalton
Intensive Cultural Resources Survey Of The Proposed City Of Conroe Stewarts Creek Wastewater System Improvements Project, Conroe, Montgomery County, Texas, Jeffrey D. Owens, Jesse O. Dalton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by LJA Engineering, Inc. (LJA), on behalf of the City of Conroe, to conduct a cultural resources inventory and assessment for the proposed Stewarts Creek Wastewater System Improvements Project in Conroe, Montgomery County, Texas. The proposed undertaking would consist of rehabilitating and replacing approximately 2.1 kilometers (1.3 miles) of existing gravity sewer pipeline that runs along the western terraces of Stewarts Creek in the southeastern portion of Conroe. The segment of the existing sewer line proposed for rehabilitation and replacement runs along the western terraces of Stewarts Creek extending from Avenue M southward …
Report On The Results Of Eligibility Testing At Site 41tv222 For The Webberville Park New Maintenance Facility Project, Travis County, Texas, Will Pratt, Josh Haefner
Report On The Results Of Eligibility Testing At Site 41tv222 For The Webberville Park New Maintenance Facility Project, Travis County, Texas, Will Pratt, Josh Haefner
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
In January 2016, Hicks & Company conducted eligibility testing at Site 41TV222 located within Webberville Park, Travis County, Texas. The investigations were conducted on behalf of Travis County under Texas Antiquities Permit #7513 in preparation for the proposed construction of a new maintenance building, an associated paved parking area, new walkways, and park lighting.
The area of potential effects (APE) for the proposed improvements both overlays and is immediately adjacent to the boundaries of Site 41TV222 as depicted on the Texas Historical Commission’s (THC’s) Archeological Sites Atlas. This site was previously determined eligible as a State Antiquities Landmark. Prior to …
Cultural Resources Investigations For The University Of Texas Health Science Center At San Antonio Project, Bexar County, Texas, Sophia Salgado, Laura Clark
Cultural Resources Investigations For The University Of Texas Health Science Center At San Antonio Project, Bexar County, Texas, Sophia Salgado, Laura Clark
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
At the request of TriLeaf Corporation (TriLeaf), SWCA Environmental Consultants (SWCA) conducted a cultural resources investigation for the University of Texas Health Science Center at San Antonio (UTHSCSA) Project (Project) located in Bexar County, Texas. The Project involves the installation of a 432-foot-long (132-meter [m]-long) fiber-optic communication line directly south of Floyd Curl Drive in northwest San Antonio, Texas. The total disturbance of the proposed Project area measures approximately 0.28 acre (0.1 hectare [ha]) in size. The Project area is situated on the grounds of UTHSCSA and located approximately 8.48 miles (13.65 kilometers [km]) from downtown San Antonio. At its …
Cultural Resources Survey For The City Of Cleburne's Proposed Reuse Corridor Pipeline Johnson County, Texas, Garrett Wheaton
Cultural Resources Survey For The City Of Cleburne's Proposed Reuse Corridor Pipeline Johnson County, Texas, Garrett Wheaton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
In May 2020, AmaTerra Environmental, Inc. (AmaTerra) performed a cultural resources survey on behalf of The City of Cleburne Texas (City) and their engineering contractor Freese and Nichols Inc. (FNI), prior to the construction of a new reuse water line near Cleburne, Johnson County, Texas. The City is proposing to install five miles of reuse water line from the City’s wastewater treatment plant to the Nolan River at the northern end of Lake Pat Cleburne. As the City of Cleburne is a political subdivision of the State of Texas, it is subject to the Antiquities Code of Texas (ACT), requiring …
Intensive Cultural Resources Survey Of The 11.4-Acre Northwest Drive At Green Hill Road Tract, San Angelo, Tom Green County, Texas, Jesse O. Dalton, Jeffery D. Owens
Intensive Cultural Resources Survey Of The 11.4-Acre Northwest Drive At Green Hill Road Tract, San Angelo, Tom Green County, Texas, Jesse O. Dalton, Jeffery D. Owens
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by Mason Joseph Company, Inc. (Mason Joseph) to conduct a cultural resources survey and assessment for a proposed apartment complex development located on an approximately 4.6-hectare (11.4-acre) tract in San Angelo, Tom Green County, Texas. The proposed apartment complex would be located on undeveloped land in western San Angelo just northwest of the intersection of Northwest Drive and Green Hill Road. For the purposes of the cultural resources survey, the project area was assumed to consist of the entire 4.6-hectare (11.4-acre) tract.
The proposed undertaking would be sponsored by Mason Joseph, a private …
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Michael Quennoz
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Michael Quennoz
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
This report summarizes the results of a cultural resources survey by Gray & Pape, Inc., on behalf of their client, BIO-WEST, Inc., of six workspaces within four discontiguous locations along Big Creek in Fort Bend County, Texas totaling 6.1 hectares (15.1 acres) and approximately 1.5 kilometers (0.9 miles) in length. The Big Creek Channel Repair Project calls for bank stabilization efforts at each of the four locations. The goals of the survey were to determine if the proposed project would affect any previously identified archaeological sites as defined by Section 106 of the National Historic Preservation Act of 1966, as …
Intensive Cultural Resources Survey Of The Proposed 54.5-Acre Country Club Road Tract, Conroe, Montgomery County, Texas, Charles E. Bludau, Jeffery D. Owens Jr., Jesse O. Dalton
Intensive Cultural Resources Survey Of The Proposed 54.5-Acre Country Club Road Tract, Conroe, Montgomery County, Texas, Charles E. Bludau, Jeffery D. Owens Jr., Jesse O. Dalton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by Forestar Real Estate Group, Inc. to conduct a cultural resources inventory and assessment for the proposed 22.1- hectare (54.5-acre) Country Club Road tract in Conroe, Montgomery County, Texas. The proposed development tract is located in a largely undeveloped forested area south of the Conroe Country Club, east of Old Country Club Road, and north of Farm-to-Market Road (FM) 2854 in western Conroe. For purposes of the cultural resources survey, the project area is assumed to consist of the entire 22.1-hectare (54.5-acre) tract.
The proposed undertaking would be sponsored by a private real …
Marine Archaeological Survey At The Texas Park And Wildlife Department’S Towhead Reef Site, Aransas Bay, Aransas County, Texas, Amanda Evans, John Rawls, Michael Quennoz, James Hughey
Marine Archaeological Survey At The Texas Park And Wildlife Department’S Towhead Reef Site, Aransas Bay, Aransas County, Texas, Amanda Evans, John Rawls, Michael Quennoz, James Hughey
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Under contract to the Texas Parks and Wildlife Department, Gray & Pape, Inc., of Houston, Texas, conducted a Phase I marine archaeological survey for the Texas Parks and Wildlife Department’s Towhead Reef Project in Aransas Bay, Aransas County, Texas. The archaeological survey was sponsored by the Texas Parks and Wildlife Department. The Area of Potential Effect for the proposed Towhead Reef Project is a 74.9-hectare (185-acre) submerged, rectangular tract within Aransas Bay. Work was completed under Texas Antiquities Permit Number 9513. The United States Army Corps of Engineers, Galveston District has been identified as the lead federal agency, and the …
Marine Archaeological Survey At The Texas Park And Wildlife Department’S North Todd, Resignation, And South Dollar Reef Sites, Galveston Bay, Chambers And Galveston Counties, Texas, Amanda Evans, Michael Quennoz, John Rawls, Jim Hughey
Marine Archaeological Survey At The Texas Park And Wildlife Department’S North Todd, Resignation, And South Dollar Reef Sites, Galveston Bay, Chambers And Galveston Counties, Texas, Amanda Evans, Michael Quennoz, John Rawls, Jim Hughey
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Under contract to the Texas Parks and Wildlife Department, Gray & Pape, Inc., of Houston, Texas, conducted a Phase I marine archaeological survey for the Texas Parks and Wildlife Department’s North Todd, Resignation, and South Dollar proposed artificial reef sites in Chambers and Galveston Counties, Texas. The archaeological survey was sponsored by the Texas Parks and Wildlife Department. The Areas of Potential Effect for the proposed reef sites cover an approximate total of 84.4 hectares (209 acres) over three separate project areas. All three areas are on National Oceanic and Atmospheric Administration nautical chart #11327, Upper Galveston Bay – Houston …
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Michael Quennoz
Cultural Resources Survey For The Big Creek Channel Repair Project In Fort Bend County, Texas, Michael Quennoz
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
This report summarizes the results of a cultural resources survey by Gray & Pape, Inc., on behalf of their client, BIO-WEST, Inc., of six workspaces within four discontiguous locations along Big Creek in Fort Bend County, Texas totaling 6.1 hectares (15.1 acres) and approximately 1.5 kilometers (0.9 miles) in length. The Big Creek Channel Repair Project calls for bank stabilization efforts at each of the four locations. The goals of the survey were to determine if the proposed project would affect any previously identified archaeological sites as defined by Section 106 of the National Historic Preservation Act of 1966, as …
Cultural Resources Inventory Of 60.2 Acres For The Proposed El Paso Central Processing Center Project, El Paso, U.S. Customs And Border Protection, El Paso Sector, El Paso County, Texas, John Lindemuth
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
GSRC personnel conducted an intensive cultural resources survey of a 60.2-acre parcel for the construction, operation, and maintenance of a permanent U.S. Border Patrol (USBP) Central Processing Center (CPC) facility located in northeast El Paso, El Paso County, Texas. No previously recorded archaeological sites or previously conducted archaeological investigations were found to overlap with the 60.2-acre survey parcel. No aboveground/architectural historic properties were noted within the 1.6-kilomter (1-mile) search radius of the 60.2-acre survey parcel. Fieldwork for the survey was conducted by the Principal Investigator and an archaeological technician over a 5-day period from February 24 to 28, 2020. The …
Intensive Cultural Resources Survey Of The 380.6-Acre Stockdick School Road Tract, Katy, Harris County, Texas, Jeffrey D. Owens, Charles E. Bludau Jr., Jesse O. Dalton
Intensive Cultural Resources Survey Of The 380.6-Acre Stockdick School Road Tract, Katy, Harris County, Texas, Jeffrey D. Owens, Charles E. Bludau Jr., Jesse O. Dalton
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
Horizon Environmental Services, Inc. (Horizon) was selected by Berg-Oliver Associates, Inc. (BOA) on behalf of the Harris County Flood Control District (HCFCD) to conduct a cultural resources inventory and assessment for the proposed Stockdick School Road Project in Katy, Harris County, Texas (HCFCD Project No. U501-07-00-E001). The proposed undertaking would consist of constructing various storm water detention ponds and other drainage improvements within a non-contiguous 154.0-hectare (380.6-acre) tract located off either side of Grand Avenue Parkway (State Highway [SH] 99) in Katy, Harris County, Texas. The tract is bounded on the north by Stockdick School Road, on the west by …
Intensive Pedestrian Survey Of The Eisenhower Trail Segment,Howard Peak Greenway Trail, San Antonio, Bexar County, Texas, Sarah Wigley
Intensive Pedestrian Survey Of The Eisenhower Trail Segment,Howard Peak Greenway Trail, San Antonio, Bexar County, Texas, Sarah Wigley
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
On May 19-21, 2020, the Center for Archaeological Research (CAR) at The University of Texas at San Antonio (UTSA) conducted an intensive pedestrian survey of the Eisenhower Park Trail Segment of the Howard Peak Greenway Trail in northwest San Antonio, Bexar County, Texas. The work was conducted in response to a request from Adams Environmental, Inc. The original alignment of the trail (The Rim to Eisenhower Park) had been surveyed previously by CAR in 2015, but a redesign necessitated a survey of this portion of the trail segment. This portion of the trail was redesigned because the slope of the …
Cultural Resources Survey Of The Proposed Cps Energy Shepherd Transmission Line Project, Bexar County, Texas, Sophia Salgado, Zachary M. Overfield
Cultural Resources Survey Of The Proposed Cps Energy Shepherd Transmission Line Project, Bexar County, Texas, Sophia Salgado, Zachary M. Overfield
Index of Texas Archaeology: Open Access Gray Literature from the Lone Star State
SWCA Environmental Consultants (SWCA) conducted a cultural resources investigation on behalf of CPS Energy for the proposed 5.6-mile-long (9-kilometer [km]-long) Shepherd Transmission Line Project in Bexar County, Texas (Project). The Project will involve installing new overhead electric transmission monopoles within west San Antonio. The Project is currently not subject to Section 106 of the National Historic Preservation Act (NHPA) but is subject to the Antiquities Code of Texas (ACT) and Historic Preservation and Design Sections of San Antonio’s Unified Development Code, both closely aligned to NHPA standards. The purpose of the investigation was to identify any substantial cultural resources sites …
A Parallel-Group, Multicenter Randomized, Double-Blinded, Placebo-Controlled, Phase 2/3, Clinical Trial To Test The Efficacy Of Pyridostigmine Bromide At Low Doses To Reduce Mortality Or Invasive Mechanical Ventilation In Adults With Severe Sars-Cov-2 Infection: The Pyridostigmine In Severe Covid-19 (Pisco) Trial Protocol, S. Fragoso-Saavedra, D. A. Iruegas-Nunez, A. Quintero-Villegas, H. B. García-González, I. Nuñez, S. L. Carbajal-Morelos, B. M. Audelo-Cruz, S. Arias-Martínez, Y. Caro-Vega, S. I. Valdés-Ferrer, +7 Additional Authors
A Parallel-Group, Multicenter Randomized, Double-Blinded, Placebo-Controlled, Phase 2/3, Clinical Trial To Test The Efficacy Of Pyridostigmine Bromide At Low Doses To Reduce Mortality Or Invasive Mechanical Ventilation In Adults With Severe Sars-Cov-2 Infection: The Pyridostigmine In Severe Covid-19 (Pisco) Trial Protocol, S. Fragoso-Saavedra, D. A. Iruegas-Nunez, A. Quintero-Villegas, H. B. García-González, I. Nuñez, S. L. Carbajal-Morelos, B. M. Audelo-Cruz, S. Arias-Martínez, Y. Caro-Vega, S. I. Valdés-Ferrer, +7 Additional Authors
Journal Articles
© 2020, The Author(s). Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative agent of coronavirus disease 2019 (COVID-19), may lead to severe systemic inflammatory response, pulmonary damage, and even acute respiratory distress syndrome (ARDS). This in turn may result in respiratory failure and in death. Experimentally, acetylcholine (ACh) modulates the acute inflammatory response, a neuro-immune mechanism known as the inflammatory reflex. Recent clinical evidence suggest that electrical and chemical stimulation of the inflammatory reflex may reduce the burden of inflammation in chronic inflammatory diseases. Pyridostigmine (PDG), an ACh-esterase inhibitor (i-ACh-e), increases the half-life of endogenous ACh, therefore …
Bioethical Issues In Genome Editing By Crispr-Cas9 Technology, Fatma Betül Ayanoğlu, Ayşe Eser Elçi̇n, Yaşar Murat Elçi̇n
Bioethical Issues In Genome Editing By Crispr-Cas9 Technology, Fatma Betül Ayanoğlu, Ayşe Eser Elçi̇n, Yaşar Murat Elçi̇n
Turkish Journal of Biology
Genome editing technologies have led to fundamental changes in genetic science. Among them, CRISPR-Cas9 technology particularly stands out due to its advantages such as easy handling, high accuracy, and low cost. It has made a quick introduction in fields related to humans, animals, and the environment, while raising difficult questions, applications, concerns, and bioethical issues to be discussed. Most concerns stem from the use of CRISPR-Cas9 to genetically alter human germline cells and embryos (called germline genome editing). Germline genome editing leads to serial bioethical issues, such as the occurrence of undesirable changes in the genome, from whom and how …
Finding Light In The Darkness: The Role Of Humor, Edward F. Ansello
Finding Light In The Darkness: The Role Of Humor, Edward F. Ansello
Director's Editorials from Age in Action
The human story of confrontations with darkness can be lightened with the aid of humor and laughter.
Brain Disease Detection From Eegs: Comparing Spiking And Recurrent Neural Networks For Non-Stationary Time Series Classification, Hristo Stoev
Dissertations
Modeling non-stationary time series data is a difficult problem area in AI, due to the fact that the statistical properties of the data change as the time series progresses. This complicates the classification of non-stationary time series, which is a method used in the detection of brain diseases from EEGs. Various techniques have been developed in the field of deep learning for tackling this problem, with recurrent neural networks (RNN) approaches utilising Long short-term memory (LSTM) architectures achieving a high degree of success. This study implements a new, spiking neural network-based approach to time series classification for the purpose of …