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Placental Expression Of Angiopoietin-1, Angiopoietin-2 And Tie-2 During Placental Development In An Ovine Model Of Placental Insufficiency-Fetal Growth Restriction., Amy S Erickson Hagen, Ryan J Orbus, Randall B Wilkening, Timothy Regnault, Russell V Anthony

Paediatrics Publications

Fetal growth restriction (FGR) is associated with increased perinatal morbidity and mortality, and often results from functional placental insufficiency. Placentation requires extensive vasculogenesis and subsequent angiogenesis, in both maternal and fetal tissues. Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are angiogenic growth factors expressed in the placenta, and compete for binding to a common receptor, Tunica interna endothelial cell kinase-2 (Tie-2). Our objective was to examine Ang-1, Ang-2 and Tie-2 expression in ovine placental tissue obtained from normal and FGR pregnancies throughout gestation. Fetal cotyledon and maternal caruncle tissue concentrations of Ang-1, Ang-2 and Tie-2 mRNA were assessed by real-time reverse transcriptase-polymerase …

Editor's Notes And Front Matter, Suzanne Majhanovich

Comparative and International Education / Éducation Comparée et Internationale

No abstract provided.

La Guerre Et Le Génocide De 1994: Impacts Et Nouveaux Espoirs Sur L'Éducation Des Jeunes Filles Au Rwanda, Donatille Mujawamariya, Susan Judith Ship

Comparative and International Education / Éducation Comparée et Internationale

A travers un cadre theorique femme/genre et developpement, les auteures menent une discussion sur la sous-scolarisation des filles au Rwanda. Elles explorent ensuite comment les inegalites de genre interagissent avec des inegalites socioeconomiques et regionales pour entraver l'acces equitable et la participation des filles it l'education formelle au cours des periodes coloniale, apres l'independance et postgenocide. Dans la suite, elles montrent comment les organisations de femmes jouent, actuellement, un role crucial dans la promotion de l'empowerment des filles et l'equite de genre en education a travers la conscientisation a la problematique de genre, des programmes et activites innovateurs.

The authors …

Decolonizing Indigenons Education: Beyond Culturalism: Toward Post-Cultural Strategies, Yatta Kanu

Comparative and International Education / Éducation Comparée et Internationale

As a response to the recent international calls to decolonize the education of Indigenous students and increase school success among them by including indigenous knowledge into school curricula, aspects of Aboriginall cultural knowledge/perspectives were integrated into the Social Studies curriculum in a Canadian inner city school in order to appraise the effect on academic achievement, class attendance and school retention among some Canadian Aboriginal students. Results suggest some optimism about increasing school success among these students by integrating Aboriginal perspectives. Five effective approaches to the integration of Indigenous perspectives into the school curriculum and some critical elements of instruction that …

Privatization Chinese Style: Tuition Reforms In China's Postsecondary Education, Lanlin Zhang

Comparative and International Education / Éducation Comparée et Internationale

Since the endorsement of a socialist market economy in 1992 in the 14th National Congress of the Chinese Communist Party, self-financing and fee-charging principles have been widely adopted, and finally legitimized in China's higher education system. However, refonns in China's post secondary education, mainly privatization and tuition fee hikes, have produced some serious controversies and concerns among students, parents, and international education researchers. This article delves into the issues of post secondary education refonn in China and brings into attention problems that occur when policies are institutionalized in a centralized decentralization setting.

Depuis l'adhesion a une economie de marche socialiste …

Book Reviews

Comparative and International Education / Éducation Comparée et Internationale

No abstract provided.

Cie Journal/Revue Eci 34(1) & 34(2) Referees/Critiques

Comparative and International Education / Éducation Comparée et Internationale

No abstract provided.

Recherche Comparée Sur La Prise De Parole De Certains Élèves Du Préscolaire Au Primaire En Français Langue Maternelle En France Et Au Québec, Lizanne Lafontaine, Catherine Le Cunff

Comparative and International Education / Éducation Comparée et Internationale

Cette recherche franco-quebecoise vise a valider ou a corriger des situations et des demarches isolees en enseignement de l'oral qui n'ont pu faire l'objet d'une experimentation suffisamment large. Nous poursuivons l'objectif general suivant: mieux connattre les representations de certains enseignants quebecois et francais concemant l'oral et sa place dans les apprentissages comme dans la socialisation au sein de la classe quand ils mettent en place des situations innovantes du prescolaire au secondaire. Nous expliquons les differences methodologiques entre les deux pays qui nous ont quand meme permis d'etablir des convergences ainsi que des divergences importantes entre les divers ordres d'enseignement. …

Development Of The Anxiety Change Expectancy Scale (Aces) And Validation In College, Community, And Clinical Samples., David J A Dozois, Henny A Westra

Psychology Publications

This study investigated the psychometric properties of a newly developed 20-item instrument that assesses one's anticipation of being able to change anxiety: the Anxiety Change Expectancy Scale (ACES). Study 1 evaluated the ACES in undergraduate university students, self-identified as experiencing difficulties with anxiety. Study 2 examined the ACES in a community sample of persons with anxiety difficulties. Study 3 tested the utility of the ACES in predicting treatment change in a group of individuals with generalized anxiety disorder participating in group cognitive behavioral therapy for anxiety. Across these samples, the ACES demonstrated excellent internal reliability (coefficient alphas=.89-.92) as well as …

The Cerebral Response During Subjective Choice With And Without Self-Reference, Sterling C. Johnson, Taylor W. Schmitz, Tisha N. Kawahara-Baccus, Howard A. Rowley, Andrew L. Alexander, Jonghoon Lee, Richard J. Davidson

Brain and Mind Institute Researchers' Publications

The anterior medial prefrontal (AMPFC) and retrosplenial (RSC) cortices are active during self-referential decision-making tasks such as when participants appraise traits and abilities, or current affect. Other appraisal tasks requiring an evaluative decision or mental representation, such as theory of mind and perspective-taking tasks, also involve these regions. In many instances, these types of decisions involve a subjective opinion or preference, but also a degree of ambiguity in the decision, rather than a strictly veridical response. However, this ambiguity is generally not controlled for in studies that examine self-referential decision-making. In this functional magnetic resonance imaging experiment with 17 healthy …

Cortical Regions Associated With Autonomic Cardiovascular Regulation During Lower Body Negative Pressure In Humans., Derek S Kimmerly, Deborah D O'Leary, Ravi S Menon, Joseph S Gati, J Kevin Shoemaker

Kinesiology Publications

The purpose of the present study was to determine the cortical structures involved with integrated baroreceptor-mediated modulation of autonomic cardiovascular function in conscious humans independent of changes in arterial blood pressure. We assessed the brain regions associated with lower body negative pressure (LBNP)-induced baroreflex control using functional magnetic resonance imaging with blood oxygen level-dependent (BOLD) contrast in eight healthy male volunteer subjects. The levels of LBNP administered were 5, 15 and 35 mmHg. Heart rate (HR; representing the cardiovascular response) and LBNP (representing the baroreceptor activation level) were simultaneously monitored during the scanning period. In addition, estimated central venous pressure …

Absence Of Microemboli On Transcranial Doppler Identifies Low-Risk Patients With Asymptomatic Carotid Stenosis Who Do Not Warrant Endarterectomy Or Stenting, J. David Spence, Arturo Tamayo, Stephen P. Lownie, Wai P. Ng, Gary G. Ferguson

Department of Medicine Publications

Background and Purpose - Carotid endarterectomy clearly benefits patients with symptomatic severe stenosis (SCS), but the risk of stroke is so low for asymptomatic patients (ACS) that the number needed to treat is very high. We studied transcranial Doppler (TCD) embolus detection as a method for identifying patients at higher risk who would have a lower number needed to treat. Methods - Patients with carotid stenosis of ≥60% by Doppler ultrasound who had never been symptomatic (81%) or had been asymptomatic for at least 18 months (19%) were studied with TCD embolus detection for up to 1 hour on 2 …

Hogging The Remote (Search Button): How Western Libraries Is Using Remote Searching To Streamline Acquisitions, Paul Hamilton, Karen Marshall

Western Libraries Presentations

This presentation discusses how Western Libraries at the University of Western Ontario used remote searching to streamline acquisitions.

Fostering Interactions: The Networking Needs Of Community Health Nursing Researchers And Decision Makers, Anita Kothari, Nancy Edwards, Susan Brajtman, Barbara Campbell, Nadia Hamel, Frances Legault, Judy Mill, Ruta Valaitis

Health Studies Publications

The purpose of the study on which this article is based was to determine the current extent of linkages among Canadian community health nursing researchers and decision makers and to identify perceptions around the structure and function of potential networks. A qualitative research design was utilised to develop common themes across focus groups, a workshop and key informant interviews. The findings suggest that there is a need for a formal community health network to provide an efficient and timely means to link the expertise required to tackle complex community health policy problems, and to create supports for advancing community health …

Clinical Kidney Transplantation: A 50th Anniversary Review Of The First Reported Series, Vivian Charles Mcalister

Surgery Publications

BACKGROUND: Histories of kidney transplantation rarely mention a series reported by Gordon Murray of Toronto and published by the American Journal of Surgery 50 years ago.

METHODS: The papers and biographies of Gordon Murray were reviewed in the context of knowledge at that time about renal failure management to determine their contribution to transplantation research and to current practice.

RESULTS: Murray proceeded from a unique leadership position in vascular surgery, anticoagulation therapy, and dialysis to undertake a rational series of animal experiments and human trials of kidney transplantation that led him to the practices of graft irrigation, cold storage, pelvic …

What Happens To The ‘Healthy Immigrant Effect’: The Mental Health Of Immigrants To Canada, Yimin Lou, Roderic Beaujot

PSC Discussion Papers Series

This study examines the mental health of Canada’s immigrants, relative to that of the native-born population, and makes a comparison between the longer term (ten or more years of residence) and more recent immigrants. The pattern of mental health may be explained by selectivity, structural strain theory from a macro perspective, or stress theory with a micro approach. Given available data, the study focuses on stress theory which suggests that persons with better mental health are either exposed to fewer stressors, or they cope better with their stress and adversity. The data are from Cycle 1.2 of the Canadian Community …

Why Are Canadians Having Children? An Investigation Of The Value Attributed To Children And Its Impact On Demand For Children, Melissa H. Moyser

PSC Discussion Papers Series

Previous studies in the value-of-children tradition of fertility research have examined the effect on demand for children of subjective perceptions of a particular value, or category of values, of children to parents. In their explanation of demand for children, they do not consider the possibility of the relevance of multiple or diverse single-handed values of children to parents. By investigating the impact of a non-specific measure of the values of children to parents—the value attributed to children—on demand for children, this study implicitly takes into account all of the values of children to parents that may be implicated in demand …

Aggregate Level Community Characteristics And Health, Jianlin Niu, Roderic Beaujot

PSC Discussion Papers Series

This study links aggregate data from the 2001 census to individual data from the Canadian Community Health Survey, using dissemination areas as the unit of aggregation. Individual-level considerations are found to be more important to self-perceived health than community-level characteristics. Education and income adequacy are the most important considerations. Sense of belonging to community overshadows the features measured at the aggregate level, be they economic, family, cultural or geographic considerations.

Polygamous Marital Structure And Child Survivorship In Ghana: Age Dependent Effect?, Stephen Obeng Gyimah

PSC Discussion Papers Series

A key limitation of existing research on the influence of family structure on child outcomes in cultures characterized by widespread polygamy is the implicit view of marriage as monolithic and by default monogamous. In the African context, there is the need to make a distinction between polygamous and monogamous mothers since these marital circumstances imply varying levels of parental support necessary for optimum child outcomes. Using data from the 1998 and 2003 Ghana Demographic and Health Surveys, this paper assesses the effects of polygamy on child survivorship. The study is guided by competing theses on the interconnectedness between polygamy and …

Shifts In Social Development And Fertility Decline In Iran: A Cluster Analysis Of Provinces, 1986-1996, Amir Erfani

PSC Discussion Papers Series

Iran is experiencing the third phase of demographic transition (low levels of birth and death), following a sharp fertility decline experienced during 1986-1996 period and is still underway. Using the analytic framework of Davis and Black, we examined the impact of social development and contraceptive prevalence, respectively as the structural and proximate determinants, on rapid fertility decline in Iran. We found that the social development level of provinces had a great impact on fertility decline through contraceptive prevalence indirectly. The cluster analysis of social development indices in 1986 and 1996 revealed that 15 out of 24 provinces of Iran moved …

Roles Of Na,K-Atpase In Early Development And Trophectoderm Differentiation., Gerald M Kidder, Andrew J Watson

Obstetrics & Gynaecology Publications

Before implantation into the uterine wall, the mammalian embryo undergoes a period of cell division, cell shape change, and cell differentiation leading to the formation of an outer epithelium, the trophectoderm. The trophectoderm is the part of the embryo that initiates uterine contact and, after transformation to become the trophoblast, uterine invasion. Similar to the kidney nephron, the trophectoderm is a transporting epithelium with distinct apical and basolateral membrane domains; its function is to facilitate transepithelial Na+ and fluid transport for blastocoel formation. That transport is driven by Na,K-adenosine triphosphatase (ATPase) localized in basolateral membranes of the trophectoderm. Preimplantation embryos …

3d Ultrasound Measurement Of Change In Carotid Plaque Volume: A Tool For Rapid Evaluation Of New Therapies, Craig D. Ainsworth, Christopher C. Blake, Arturo Tamayo, Vadim Beletsky, Aaron Fenster, J. David Spence

Department of Medicine Publications

Background and Purpose - New therapies are being developed that are antiatherosclerotic but that lack intermediate end points, such as changes in plasma lipids, which can be measured to test efficacy. To study such treatments, it will be necessary to directly measure changes in atherosclerosis. The study was designed to determine sample sizes needed to detect effects of treatment using 3D ultrasound (US) measurement of carotid plaque. Methods - In 38 patients with carotid stenosis >60%, age±SD 69.42±7.87 years, 15 female, randomly assigned in a double-blind fashion to 80 mg atorvastatin daily (n=17) versus placebo (n=21), we measured 3D plaque …

P38 Mitogen-Activated Protein Kinase (Mapk) First Regulates Filamentous Actin At The 8-16-Cell Stage During Preimplantation Development., Andrew J M Paliga, David R Natale, Andrew J Watson

Obstetrics & Gynaecology Publications

BACKGROUND INFORMATION: The MAPK (mitogen-activated protein kinase) superfamily of proteins consists of four separate signalling cascades: the c-Jun N-terminal kinase or stress-activated protein kinases (JNK/SAPK); the ERKs (extracellular-signal-regulated kinases); the ERK5 or big MAPK1; and the p38 MAPK group of protein kinases, all of which are highly conserved. To date, our studies have focused on defining the role of the p38 MAPK pathway during preimplantation development. p38 MAPK regulates actin filament formation through the downstream kinases MAPKAPK2/3 (MAPK-activated protein kinase 2/3) or MAPKAPK5 [PRAK (p38 regulated/activated kinase)] and subsequently through HSP25/27 (heat-shock protein 25/27). We recently reported that 2-cell-stage murine …

Escaping From The Straightjacket That Baffled Houdini: An Analysis Of The Myths And Realities Of Empowering Toronto Through A City Charter, Luis Silva

MPA Major Research Papers

This paper examines the idea that municipalities in Canada – with a specific focus on Toronto – can be legally empowered by a legislative charter to defend their autonomy from the actions of the provincial government. Case studies that analyze the political and legal relationships that selected charter cities – Saint John, Montreal, Halifax, Winnipeg, Vancouver, and Lloydminster – have with their respective province were conducted. The findings reveal that while provinces may politically treat some municipalities differently than others, no legal differentiation exists between charter cities and other municipalities with regards to protecting local self-government.

Study Of System Parameters And Control Design For A Flexible Manipulator Using Piezoelectric Transducers, Mehrdad Kermani Ph.D., P.Eng., Mehrdad Moallem, Rajni Patel

Electrical and Computer Engineering Publications

No abstract provided.

Cohort And Social Status Differentials In Union Dissolution: Analysis Using The 2001 General Social Survey, Zenaida R. Ravanera, Rajulton Fernando, Thomas K. Burch

PSC Discussion Papers Series

Abstract not available

The Life Course Trajectories Of Older Canadians, Zenaida R. Ravanera, Rajulton Fernando, Thomas K. Burch

PSC Discussion Papers Series

Abstract not available

Community Mobilization In The Waterloo Regional Police Service: A Process Evaluation Of The Community Mobilization Initiative Of The Waterloo Regional Police Service, Matthew Torigian

MPA Major Research Papers

This paper examines the processes used by the Waterloo Regional Police Service in the implementation of the community mobilization approach based on an analysis of information gathered from a variety of sources, including stakeholder interviews, academic journals, and government reports. The findings reveal that there are disconnections within the Police Service among officers holding various ranks and responsibilities and this divide indicates confusion over the concept, philosophy, practice, and role of community mobilization and community policing.

Capital Expenditures In Metropolitan Toronto: A Comparison Of The Capital Operations And Written Literature On Capital Infrastructure For The Municipality Of Metropolitan Toronto, Caspar Hall

MPA Major Research Papers

This paper examines whether the assertions made by key literature on capital infrastructure in Metropolitan Toronto are empirically supported based on an analysis of annual capital operations financial statements. The findings reveal that, with a few exceptions, the historical analysis of capital operations does support the assertions made by the literature on capital infrastructure.

Comparing Immigrant Services, Practices, Programs, And Policies In The City Of London And The City Of Toronto: The Implications For The City Of London, Tiwei Huang

MPA Major Research Papers

This paper examines immigrant services, practices, programs, and policies in the City of Toronto in order to provide recommendations to the City of London on how to address the six key thematic areas of settlement, employment, neighbourhood, cultural competency and access to services, social inclusion, and systemic change. Interviews with key municipal government and community organization players in both cities were conducted. The findings reveal nine recommendations in the areas of systemic change, settlement, employment, and neighbourhood to improve immigrant services, practices, programs, and policies in London.