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Interaction Of High-Fat Diet And Brain Trauma Alters Adipose Tissue Macrophages And Brain Microglia Associated With Exacerbated Cognitive Dysfunction, Rebecca J Henry, James P Barrett, Maria Vaida, Niaz Z Khan, Oleg Makarevich, Rodney M Ritzel, Alan I Faden, Bogdan A Stoica Apr 2024

Interaction Of High-Fat Diet And Brain Trauma Alters Adipose Tissue Macrophages And Brain Microglia Associated With Exacerbated Cognitive Dysfunction, Rebecca J Henry, James P Barrett, Maria Vaida, Niaz Z Khan, Oleg Makarevich, Rodney M Ritzel, Alan I Faden, Bogdan A Stoica

Faculty, Staff and Student Publications

Obesity increases the morbidity and mortality of traumatic brain injury (TBI). Detailed analyses of transcriptomic changes in the brain and adipose tissue were performed to elucidate the interactive effects between high-fat diet-induced obesity (DIO) and TBI. Adult male mice were fed a high-fat diet (HFD) for 12 weeks prior to experimental TBI and continuing after injury. High-throughput transcriptomic analysis using Nanostring panels of the total visceral adipose tissue (VAT) and cellular components in the brain, followed by unsupervised clustering, principal component analysis, and IPA pathway analysis were used to determine shifts in gene expression patterns and molecular pathway activity. Cellular …


Interaction Of High-Fat Diet And Brain Trauma Alters Adipose Tissue Macrophages And Brain Microglia Associated With Exacerbated Cognitive Dysfunction, Rebecca J Henry, James P Barrett, Maria Vaida, Niaz Z Khan, Oleg Makarevich, Rodney M Ritzel, Alan I Faden, Bogdan A Stoica Apr 2024

Interaction Of High-Fat Diet And Brain Trauma Alters Adipose Tissue Macrophages And Brain Microglia Associated With Exacerbated Cognitive Dysfunction, Rebecca J Henry, James P Barrett, Maria Vaida, Niaz Z Khan, Oleg Makarevich, Rodney M Ritzel, Alan I Faden, Bogdan A Stoica

Faculty, Staff and Student Publications

Obesity increases the morbidity and mortality of traumatic brain injury (TBI). Detailed analyses of transcriptomic changes in the brain and adipose tissue were performed to elucidate the interactive effects between high-fat diet-induced obesity (DIO) and TBI. Adult male mice were fed a high-fat diet (HFD) for 12 weeks prior to experimental TBI and continuing after injury. High-throughput transcriptomic analysis using Nanostring panels of the total visceral adipose tissue (VAT) and cellular components in the brain, followed by unsupervised clustering, principal component analysis, and IPA pathway analysis were used to determine shifts in gene expression patterns and molecular pathway activity. Cellular …


"I'Ll Stay Where You Want Me To Stay": How Latter-Day Saints Navigate Conflicting Social Values While Remaining Committed To Their Faith, Venice Jardine Apr 2024

"I'Ll Stay Where You Want Me To Stay": How Latter-Day Saints Navigate Conflicting Social Values While Remaining Committed To Their Faith, Venice Jardine

Theses and Dissertations

While recent efforts in religious studies have focused on why many Americans seem to be leaving religion entirely, much less is understood about why many others choose to remain committed to their faith--especially when they hold many of the same social values, doubts, or divergent opinions that others cite for leaving. Within a Latter-day Saint context especially, very little research has been done to explore the experiences of those navigating the complexities of competing ethical affordances while remaining committed to their faith. Through ethnographic research in both Salt Lake County and New York City, I document the patterns and processes …


Affect Variability And Cortisol In Context: The Moderating Roles Of Mean Affect And Stress, Brooke N. Jenkins, Logan T. Martin, Hee Youn (Helen) Lee, John F. Hunter, Amanda M. Acevedo, Sarah D. Pressman Apr 2024

Affect Variability And Cortisol In Context: The Moderating Roles Of Mean Affect And Stress, Brooke N. Jenkins, Logan T. Martin, Hee Youn (Helen) Lee, John F. Hunter, Amanda M. Acevedo, Sarah D. Pressman

Psychology Faculty Articles and Research

Positive and negative affect have been shown to have implications for hormones like cortisol but how moment to moment changes in affect (i.e., affect variability) influence cortisol secretion is less well understood. Additionally, context characteristics such as mean affect and stress may influence the association between affect variability and cortisol output. In the current study, we examined affect, stress, and cortisol data from 113 participants (age range = 25–63, M = 35.63, SD = 11.34; 29 % male; 42 % White/Caucasian, 37 % Asian or Pacific Islander, 13 % Hispanic/Latino, 4 % Black/African American, 1 % Native American, Eskimo, or …


Assessing Brain Processing Deficits Using Neuropsychological And Vision-Specific Tests For Concussion, Brent A. Harper, Rahul Soangra Apr 2024

Assessing Brain Processing Deficits Using Neuropsychological And Vision-Specific Tests For Concussion, Brent A. Harper, Rahul Soangra

Physical Therapy Faculty Articles and Research

Introduction: Since verbal memory and visual processing transpire within analogous cerebral regions, this study assessed (i) if a visual function can predict verbal memory performance. It also hypothesized whether neurocognitive (e.g., ImPACT) tests focusing on the Visual Memory and Cognitive Efficacy Index will predict Verbal Memory scores and (ii) if vision metrics and age can identify individuals with a history of concussion. Finally, it also hypothesized that King–Devick and near point of convergence scores alongside age considerations will identify candidates with a prior reported history of concussion. Materials and methods: This observational cohort assessed 25 collegiate ice hockey players prior …


Out Of Sight, Out Of Mind: The Hidden Issues And Entertainment Within The World Of Crime And Punishment, John Charlton, Christian Sorrells, Aaron Burney, Jonathan Yi Apr 2024

Out Of Sight, Out Of Mind: The Hidden Issues And Entertainment Within The World Of Crime And Punishment, John Charlton, Christian Sorrells, Aaron Burney, Jonathan Yi

ENGL 1102 Showcase

An anthology diving into observing topics related to crime and punishment and determining the effect on the greater topic. Explains why people are so interested in crime, how PTSD can lead to violence and questioning how prisoners spend their time and all through provoking questions addressed in this anthology in the hope that it creates a greater understanding of crime and punishment as a whole.


An Evidence-Based Strategy For The Use Of Simulation To Assess Situation Awareness In Applicants To Nurse Anesthesia Programs, Angela Lee Apr 2024

An Evidence-Based Strategy For The Use Of Simulation To Assess Situation Awareness In Applicants To Nurse Anesthesia Programs, Angela Lee

Doctor of Nursing Practice Scholarly Projects

Medical errors are considered one of the top causes of patient death. Closed claims analysis reveals an estimated 50% of claims are associated with preventable events by the anesthesia provider. Errors in anesthesia leading to critical incidents are associated with errors in situation awareness (SA). Identification of human factor variables, such as SA, provides an analysis of observable behavior and intuition necessary to guide crisis management, maintain clinical performance, and mitigate errors in patient safety. The human factor components of human error and SA play critical roles in patient safety and overall clinical anesthesia practice. The viability of simulation assessment …


No. 18: Refugee Protection And Food Security In Kampala, Uganda, Andrea M. Brown Apr 2024

No. 18: Refugee Protection And Food Security In Kampala, Uganda, Andrea M. Brown

Migration and Food Security (MiFOOD) Network

This study proposes strategies to better recognize and protect the food security needs of Kampala’s refugee population. Uganda is Africa’s largest refugee host, with a policy approach that has been widely lauded for its flexible settlement provisions and commitment to durable solutions. However, growing refugee populations and underfunding have led to serious pressures, severely exacerbated during the COVID-19 pandemic. Food insecurity in designated refugee settlements is at critical levels: 75% of residents are food insecure. One unique aspect of Uganda’s refugee governance approach is the allowance of refugee populations to self-settle outside of designated camps, in the capital city, Kampala. …


Evidence Based Practice Guidelines For The Pediatric Autistic Spectrum Disorder Population, Calvin Sparks Apr 2024

Evidence Based Practice Guidelines For The Pediatric Autistic Spectrum Disorder Population, Calvin Sparks

Doctor of Nursing Practice Scholarly Projects

Children with autism spectrum disorder (ASD), as well as caregivers, experience significant challenges in their interactions with healthcare providers in a clinical setting. This is primarily due to their issues with communication, social interaction, and sensory sensitivities to anesthetic treatment during premedication or preoperative environments. Due to these characteristics, it is important to maintain and update the current standards of care for children with ASD while utilizing evidence-guided strategies to provide a pre-operative assessment effectively. The pre-operative assessment is a critical component that renders impact throughout the surgical experience with the purpose of risk stratification, preparation of altering the normal …


"My Hideous Progeny": Complicating Preconceived Notions Of Monstrous Beings In "Frankenstein" And "Jurassic Park", Megan Engstrom Apr 2024

"My Hideous Progeny": Complicating Preconceived Notions Of Monstrous Beings In "Frankenstein" And "Jurassic Park", Megan Engstrom

English

This project examines and complicates preconceived notions of the monstrous in Frankenstein and Jurassic Park. By engaging with monster theory, I interrogate how the creators are destructive beings and their creations are only trying to fit into their made bodies. I also complicate the ideas of family when interacting with monsters or monstrous places – specifically looking at how isolation/creation of them will affect people. These ideas are questioned to confront a normalized perception of monsters as the villains. By examining the monstrous in Frankenstein and Jurassic Park, I am questioning the very idea of how a monster is created …


General Anesthesia Clinical Practice Guidelines For Patients With Posttraumatic Stress Disorder, Bradley Closson Apr 2024

General Anesthesia Clinical Practice Guidelines For Patients With Posttraumatic Stress Disorder, Bradley Closson

Doctor of Nursing Practice Scholarly Projects

General anesthesia is an induced state of unconsciousness administered by anesthesia providers to obtain patient amnesia, analgesia, and akinesia. Adult patients with posttraumatic stress disorder (PTSD) are at risk for general anesthesia-related complications throughout the perioperative setting. Emergence delirium is a clinically significant postoperative complication that patients with PTSD have an increased risk of developing. Postoperative complications of emergence delirium include patient or medical staff injury, surgical site damage, prolonged postanesthesia care unit (PACU) stay, and increased medical care costs. Evidence demonstrates that implementing preventive interventions decreases the incidence of emergence delirium. There are no standardized, evidence-based general anesthesia guidelines …


Incorporation Of Mindfulness Application Use In Doctoral Nurse Anesthesia Curricula For Mitigation Of Stress And Anxiety In Student Registered Nurse Anesthetists, Kerrie Rodgers Apr 2024

Incorporation Of Mindfulness Application Use In Doctoral Nurse Anesthesia Curricula For Mitigation Of Stress And Anxiety In Student Registered Nurse Anesthetists, Kerrie Rodgers

Doctor of Nursing Practice Scholarly Projects

The nurse anesthesia specialty is highly stressful, with educational training being no exception. High didactic demands and intensive clinical experiences are placed on student registered nurse anesthetists (SRNAs), increasing stress and anxiety in their personal and professional lives. High levels of psychological distress can lead to inadvertent consequences in students’ mental, emotional, and physical health and can contribute to illness, burnout, substance use, and compromise in patient safety. Some degree of stress is necessary for motivation to succeed and perform at high levels, and encountering stress while enrolled in a doctoral nurse anesthesia program is expected and unavoidable. A search …


Evaluating Nurses’ Turnover Intention And Organizational Commitment Following Stroke Unit Staffing Changes: An Evidence-Based Quality Initiative, Heather Tatusko Apr 2024

Evaluating Nurses’ Turnover Intention And Organizational Commitment Following Stroke Unit Staffing Changes: An Evidence-Based Quality Initiative, Heather Tatusko

Doctor of Nursing Practice Scholarly Projects

Nurses are known to be overworked, overwhelmed, undervalued, and understaffed at dangerous levels throughout various inpatient hospital units across the United States (U.S.). Hospital registered nurse (RN) turnover is a significant issue that has accelerated since the COVID-19 pandemic, resulting in economic impacts and other burdens for organizations, individuals, and communities. Evidence suggests that evaluating Registered Nurses’ Turnover intention (NTI) and Organizational Commitment (OC) can help maintain a ready and capable team of skilled RNs; however, most healthcare organizations (HCOs) do not collect or analyze NTI and OC data and focus on staffing numbers and monetary incentives to get adequate …


Evaluating Nurses’ Turnover Intention And Organizational Commitment Following Stroke Unit Staffing Changes: An Evidence-Based Quality Initiative, Heather M. Tatusko Phiri Apr 2024

Evaluating Nurses’ Turnover Intention And Organizational Commitment Following Stroke Unit Staffing Changes: An Evidence-Based Quality Initiative, Heather M. Tatusko Phiri

Doctor of Nursing Practice Scholarly Projects

Nurses are known to be overworked, overwhelmed, undervalued, and understaffed at dangerous levels throughout various inpatient hospital units across the United States (U.S.). Hospital registered nurse (RN) turnover is a significant issue that has accelerated since the COVID-19 pandemic, resulting in economic impacts and other burdens for organizations, individuals, and communities. Evidence suggests that evaluating Registered Nurses’ Turnover intention (NTI) and Organizational Commitment (OC) can help maintain a ready and capable team of skilled RNs; however, most healthcare organizations (HCOs) do not collect or analyze NTI and OC data and focus on staffing numbers and monetary incentives to get adequate …


A Survey Of Nurse Preceptor Preferences Regarding Training Topics: A Descriptive Study, Janice Yao Valadez Apr 2024

A Survey Of Nurse Preceptor Preferences Regarding Training Topics: A Descriptive Study, Janice Yao Valadez

Doctoral Projects

Background: The nurse preceptor role can be as challenging and demanding as it is critical in the context of nursing shortages and burnout. The improvement of nurse preceptor training, based on preferences expressed by the nurses fulfilling this role, therefore represents a potentially important part of the solution to these problems.

Methods: A modified version of the +RN Learning Needs Assessment tool was administered to 24 nurse preceptors who precepted in the nurse residency program on two campuses of a not-for-profit Western US hospital, regarding their preferences for topics to be covered in preceptor training, as well as the sequence …


Improving Student Engagement Despite Lowering Attention Spans In The Classroom, Kaycee Lee Apr 2024

Improving Student Engagement Despite Lowering Attention Spans In The Classroom, Kaycee Lee

Senior Honors Theses

Attention spans have been decreasing throughout society for many years, partially due to the constant increase of technological advances. The average human attention span of eight seconds is particularly concerning to teachers and others in the classroom. It does not seem that the average attention span is ever going to increase, so teachers must implement intentional methods and strategies within their classroom to keep their students’ attention. Physical activities, technology and hands-on supports, small group instruction, shorter lessons, making intentional mistakes, flexible seating, and differentiated instruction are all strategies supported by research to improve student engagement within the classroom. Every …


Singing Sad Songs To The Savior: An Examination Of And Argument For Biblical Lament Songs, Kaden Hofheins Apr 2024

Singing Sad Songs To The Savior: An Examination Of And Argument For Biblical Lament Songs, Kaden Hofheins

Senior Honors Theses

Christian lament songs play an important role in the context of the local church. There are several key differences between Christian lament and secular “sad songs” that are due to Christianity’s perspective of suffering that revolves around the hope of Jesus Christ. Christian songwriters have been writing lament songs through the lens of biblical hope in Christ throughout church history. Due to the nature of lament songs and how they give voice to negative emotions, which can help people to process their grief, and the communal nature of corporate worship, it is important that local churches ensure they use lament …


Sex-Related Differences In Reaction Time During Normobaric Hypoxic Hypoxia In Physically Active University Students, Danielle Passburg Apr 2024

Sex-Related Differences In Reaction Time During Normobaric Hypoxic Hypoxia In Physically Active University Students, Danielle Passburg

Senior Honors Theses

Limited research has been completed on the sex-related differences in reaction time during hypoxic hypoxia. This is concerning due to the importance of reaction time during hypoxic hypoxia in aviation (particularly within the realm of military aviation). The purpose of this study was to examine the sex-related differences in reaction time during hypoxic hypoxia in university students. The study used a normobaric oxygen device to simulate hypoxic states and Delphi computer software to test reaction time. Subjects were physically active university students (10 females, 10 males). The results of the study showed no significant differences between sexes in reaction times …


The Impact Of Testimonies On Partner Development Strategies: Mission Work In Europe, Kimberly Witte Apr 2024

The Impact Of Testimonies On Partner Development Strategies: Mission Work In Europe, Kimberly Witte

Senior Honors Theses

This study seeks to answer how first-world missionaries can utilize research findings on the effectiveness of testimonials and apply that knowledge to partner development strategies. Research trends demonstrate that most missionaries are being sent to countries with the largest practicing Christian populations, such as those in Africa or South America, and are more likely to receive financial partnerships. Europe has a high rate of non-practicing Christians and is a cultural intersection due to the refugee crisis, leading to a need for mission work. This research will culminate in the creation of a prayer guide, highlighting testimonies of individuals impacted by …


Intergenerational Technology Co-Design Process: Reflections From Underwater Telepresence And Xr Workshops, Oksana Hagen, Marius Varga, Rory Baxter, Hannah Bradwell, Amir Aly, Dena Bazazian, Swen Gaudl, Alejandro Veliz Reyes, Ray Jones Apr 2024

Intergenerational Technology Co-Design Process: Reflections From Underwater Telepresence And Xr Workshops, Oksana Hagen, Marius Varga, Rory Baxter, Hannah Bradwell, Amir Aly, Dena Bazazian, Swen Gaudl, Alejandro Veliz Reyes, Ray Jones

School of Engineering, Computing and Mathematics

Within the Intergenerational Co-design of Novel Technologies In Coastal Communities (ICONIC) project we aim to create technologies aimed at enhancing the wellbeing of older adults through co-design workshops with both older adults (aged 50+) and younger participants (aged 16-30). This is an intermediate report summarising our reflections on the co-design of extended reality and underwater telepresence technologies. For the two technologies' core development track, we held thirteen intergenerational workshops in total, that took place between August 2023 and July 2024, with 24 older and 12 younger participants. As a result of the co-design, we are developing prototypes, including live video …


Cognitive Behavioral Therapy To Prevent Nurse Burnout In Sub-Saharan Africa, Anna C. Johnson Apr 2024

Cognitive Behavioral Therapy To Prevent Nurse Burnout In Sub-Saharan Africa, Anna C. Johnson

MSN Capstone Projects

Overall, burnout prevention has been shown to foster nurse resilience, ability to cope with stressors, teamwork, and improving the personal value of “doing good” and “being good”; the effects have been shown to last between 6 months and one year. The current evidence is strong enough to recommend a change to current nursing practice via annual Cognitive Behavioral Therapy (CBT) trainings to strengthen nurse resilience.

This researcher proposes to implement a CBT-based burnout prevention program in Ghana’s capital of Accra in sub-Saharan West Africa. There is ample evidence that African nurses face many of the same burnout issues that nurses …


The Heavy Mark Of Ptsd The Justice System Leaves On The People Going Through It., Ezavier Miller, Angel Emetuche, Sakina Ahmed Apr 2024

The Heavy Mark Of Ptsd The Justice System Leaves On The People Going Through It., Ezavier Miller, Angel Emetuche, Sakina Ahmed

ENGL 1102 Showcase

This is a paper about how the justice system in it's many forms can cause PTSD. Not only to the criminals that go through it but also the children, victims. With many process having extensive repercussion causing PSTD to take hold of the many people that seek the justice system for help or judgement.


Covid-19'S Consequences In Day-To-Day Life, Christian Mclain, Perla Guadalupe Vega Apr 2024

Covid-19'S Consequences In Day-To-Day Life, Christian Mclain, Perla Guadalupe Vega

ENGL 1102 Showcase

This anthology discusses the consequences that the Covid-19 left. These drastic changes are still visible 4 years later, in two important sectors of Georgia's economy: the Work force and the housing market. These 2 sectors collide and merge with our daily life since they take up most of our time. Homes took on the roles of offices and schools as employees and students were forced to stay home due to the pandemic. Before and after Covid 19, everything changed from the criteria of buyers in the housing market, the inventory, the reasons why it is short, in addition to the …


Theft And Entertainment, Francesco Maiolo, Bryce Mccaskill, Libbie Brown Apr 2024

Theft And Entertainment, Francesco Maiolo, Bryce Mccaskill, Libbie Brown

ENGL 1102 Showcase

An anthology that looks at the interaction between theft and entertainment. Why and how entertainment is stolen, the prevention of theft by entertainment companies, and the depiction of theft in media.


Development Of Fashion, Bryan Madeira, Gregory Kelley, Alhagi Kebbeh, Natalie Borchuck Apr 2024

Development Of Fashion, Bryan Madeira, Gregory Kelley, Alhagi Kebbeh, Natalie Borchuck

ENGL 1102 Showcase

The theme of this Anthology focuses on the development of fashion over recent years. How it has affected people in recent years and how much it has changed over the years. Specifically talking about large brands that have impacted the market. How celebrities have affected the market and made it better. Along with how the Trans community is treated in the community. How they are represented throughout the fashion business. Last talk about the developing market for sneakers. How they have become an investment rather than something to wear for active wear.


Crimes In Different Mediums Of Art, Chloe Milhouse Apr 2024

Crimes In Different Mediums Of Art, Chloe Milhouse

ENGL 1102 Showcase

There are a few different ways we see crime and art come together as one without even realizing it and there are other topics that showcase crime punishment as well. Crime can be portrayed through music. When certain artists sing about their crime-like behaviors, this can lead to people also doing that same crime because they listened to it in a song. Crime can be derived from art itself, causing people to react emotionally and criminally to something they’ve seen. Lastly it can be represented through film and TV showcasing elements of human behavior for society to see. All of …


The Hidden Scams In Business & Finance, Jake Patten, Carter Harrell, Claude Auguste, Sheldon Jerome Downing Ii Apr 2024

The Hidden Scams In Business & Finance, Jake Patten, Carter Harrell, Claude Auguste, Sheldon Jerome Downing Ii

ENGL 1102 Showcase

For our research papers, we chose to look into different kinds of scams lurking in the business world, and how they can affect businesses and society as a whole. There are hundreds of different scams at any given time, but we decided to focus on lesser-known scams that the majority of people don't even think about. These scams include rigged casinos, charity fraud, business email compromise, and embezzlement within smaller businesses.

We chose this topic in an attempt to bring more attention to the criminal side of the business world that people otherwise see as harmless. Especially with the recent …


The Mental And Physical Health Of College Students, Cole Palmer, Tiffany Strickland, Nolan Moore, Salvatore Moore, Juan Martinez Apr 2024

The Mental And Physical Health Of College Students, Cole Palmer, Tiffany Strickland, Nolan Moore, Salvatore Moore, Juan Martinez

ENGL 1102 Showcase

The physical and mental health of college students has been a big topic in recent years, and it is the one that we have chosen. Our inspiration for choosing this topic came from being college students and getting a firsthand view of this issue. Since we are college students, who are navigating the difficulties of higher education daily, we see the issues of mental and physical health in ourselves and among our peers. Exploring the interconnectedness of societal attitudes, nutrition, and physical health regarding mental health is the inspiration for these topics as well. Each individual topic in this paper …


The Fundamentals Of Claymation Films, John Hardy Apr 2024

The Fundamentals Of Claymation Films, John Hardy

ENGL 1102 Showcase

This anthology covers three different aspects of a clay-animated film. It covers the unique financial situation that clay-animated films encounter, the different psychological responses that are related to clay-animation, and the specific character creation and voice acting done for the films.


How Different Forms Of Art And Entertainment Can Affect Our Mental Well-Being, Tucker Johnson Apr 2024

How Different Forms Of Art And Entertainment Can Affect Our Mental Well-Being, Tucker Johnson

ENGL 1102 Showcase

The following paper is a complete anthology of our collective ideas. We wrote this paper from the prompt of entertainment and health. With this given prompt we divulged separate but similar ideas. Then with these ideas formulated our anthology which is the exploration of the impact of various artistic expressions and entertainment on our psychological health. This anthology shows the intersection between art, entertainment, and our mental health. We delve into how different art and entertainment mediums can influence our mental wellbeing. This exploration has been a great culmination of research and analysis. We used extensive research to shed light …