Digital Commons Network^™

Molecular Mechanisms Of Opioid Use Disorder In Human Brain Models, Emily Mendez

Dissertations and Theses (Open Access)

Opioid use disorder (OUD) is a national and global public health crisis with no end in sight. While studies from animal models hint at widespread epigenetic and transcriptomic alterations of opioid drugs, the molecular consequences of long-term exposure to opioid drugs in human brain is still unclear, and human-centered translational models are necessary to discern the human cell type-specific effects of OUD.

Using postmortem brain Brodmann area 9 (BA9) from the UTHealth Brain Collection for Research on Psychiatric Disorders, I identified angiogenic gene networks perturbed in the RNA and protein of OUD subjects, as well as downregulation of many neuron-correlated …

Leadership Development Through Athletic Experience, Antoine Grace

All Student Scholarship

This qualitative research aims to find the relationship between athletics and leadership development by examining athletes' and nonathletes' students, life, leadership experiences, and learned behaviors. The research utilized a purposive sampling to recruit a diverse group of participants from the university that classify as either student-athletes or non-sport-playing students. The collection of data from participants has been conducted using semi-structured interviews. Thematic analysis has been used to identify patterns and themes in the interview data, allowing for a meaningful understanding and interpretation based on aspects of athletes' and non-athletes' experiences. This study aims to contribute to the existing literature on …

Legislative Recommendations On Biometric Security And Privacy Jurisprudence, Joshua M. Morrow

All Student Scholarship

This project focuses on the prevalence of biometrics today, their various applications, and the biometric laws and legislations in place in the United States (U.S.) and Maine. Due to various threats and vulnerabilities imposing risk on collecting and using peoples’ biometric data, sufficient cyber protections related to citizens’ privacy rights, ethical control, and security of personally identifiable information (PII) must become necessary components of contemporary biometric laws and legislation. Without such explicit cyber protections, citizens participate in and comply with various technical domains and entities, such as private companies and governmental agencies, with minimal awareness or comprehension that their sensitive …

Conversations About Telehealth Eating Disorder Treatment: Participants Share Their Experiences, Rachel Allen Msw

All Student Scholarship

This phenomenological study explores the use of telehealth as a modality in the treatment of eating disorders through the lenses of feminist, standpoint, and social constructionist theories. At the onset of the COVID-19 pandemic, telehealth was utilized to offer continuity of service at a local, urban eating disorder treatment program in the Northeast. Post pandemic, this modality continued for staffing and accessibility reasons. However, little is known about this treatment from the perspective of service recipients. Intensive semi-structured interviews were conducted via Zoom with six adults who had completed the telehealth program to learn about individuals’ experiences with this modality. …

A Study Of Diet Culture In Lgbtqia+ Women’S Communities, Cait Rush Msw

All Student Scholarship

Diet culture is a pervasive aspect of the sociocultural environment characterized by contradictory messages about food and health, and a moral imperative to attain thinness (Jovanovski & Jaeger, 2022). Hallmarks of diet culture include body dissatisfaction, lowered self-esteem, and adverse mental and physical health outcomes (Calogero et al., 2018; Kinavey & Cool, 2019; Puhl et al., 2021). While research suggests that LGBTQIA+ community involvement may play a role in safeguarding positive body image (Dahlenburg et al., 2021; Hanley & McLaren, 2015), studies on body dissatisfaction among queer women have yielded mixed, often contradictory results. The purpose of this study was …

Towards A Decolonial Developmental Science: Adolescent Development In The Majority World Taking Center Stage, Amina Abubakar, Angelo Costa, Lixian Cui, Silvia Koller, Chidozie Nwafor, Vaishali Raval

Institute for Human Development, East Africa

While aspiring to be a diverse and global science, developmental science continues to be dominated by EuroAmerican epistemologies, researchers, and communities in its published scholarship. Adolescents in communities across Africa, Asia, the Middle East, and Latin America comprise 85% of the world's adolescent population, and yet their experiences and perspectives are marginalized in our science. Adolescents in the Majority World live in highly diverse social, cultural, political, economic, educational and healthcare contexts that contribute to their development, and we have much to learn from their experiences. This article situates the marginalization of the global majority within coloniality embedded in developmental …

May 2024 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Perceptions Of Secondary Trauma And Memory Accuracy In Criminal Justice Professionals, Kimberley D. Williams

Student Theses

Previous research has examined the association between memory and frequent and accumulated exposure to traumatic events with conflicting results (Artwohl, 2002; Conway, 2012; Honig & Sultan, 2004; Oulton et al., 2018; Strange & Takarangi, 2015). The present study aims to build on previous research by examining public perceptions of memory accuracy and secondary trauma in off-duty criminal justice professionals (CJP) and laypeople. Survey data from n = 208 participants was examined. Participants read two mock trial testimonies describing a fatal hit and run bicycle accident, one from an off-duty CJP witness and one from an off-duty non-CJP witness. Participants completed …

Suicidal Ideation Among Survivors Of Childhood Sexual Abuse: The Role Of Shame And Sexual Grooming, Aysegul Yucel

Student Theses

Childhood Sexual Abuse (CSA) is a global public health issue, with 25% of girls and 5% of boys in the U.S. reporting abuse before the age of 18. While CSA is known to increase the risk of suicidal ideation in later life, the additional psychosocial factors involved are understudied. This study investigates the impact of abuse-related shame and sexual grooming on suicidal ideation in adults with CSA histories. Data from 118 undergraduate students were analyzed using binomial logistic regression and the PROCESS macro to explore direct and indirect effects. Results show that abuse-related shame significantly predicts suicidal ideation and mediates …

Abnormality Of Early White Matter Development In Tuberous Sclerosis Complex And Autism Spectrum Disorder: Longitudinal Analysis Of Diffusion Tensor Imaging Measures, Siddharth Srivastava, Fanghan Yang, Anna K Prohl, Peter E Davis, Jamie K Capal, Rajna Filip-Dhima, E Martina Bebin, Darcy A Krueger, Hope Northrup, Joyce Y Wu, Simon K Warfield, Mustafa Sahin, Bo Zhang, Tacern Study Group

Faculty, Staff and Student Publications

Background:

Abnormalities in white matter development may influence development of autism spectrum disorder in tuberous sclerosis complex (TSC). Our goals for this study were as follows: (1) use data from a longitudinal neuroimaging study of tuberous sclerosis complex (TACERN) to develop optimized linear mixed effects models for analyzing longitudinal, repeated diffusion tensor imaging metrics (fractional anisotropy, mean diffusivity) pertaining to select white matter tracts, in relation to positive Autism Diagnostic Observation Schedule–Second Edition classification at 36 months, and (2) perform an exploratory analysis using optimized models applied to all white matter tracts from these data.

Methods:

Eligible participants (3-12 months) …

Risk Evaluation In Occupational Safety And Health Research: Results From A Benchmarking Exercise Of Federal And Academic Irbs, Sarah A Felknor, Jessica M K Streit, Angela M Morley, John D Piacentino

Faculty, Staff and Student Publications

OBJECTIVE: Research involving working populations can pose unique ethical and risk evaluation challenges. The purpose of this benchmarking project was to assess how federal agencies and academic institutions approach the interpretation and application of key risk evaluation concepts in research involving workers in their places of employment.

METHODS: Key informant interviews were conducted to ascertain current practices related to assessing soundness of research design, determining risk reasonableness and research relatedness of risks, and evaluating the risk of noninvasive clinical tests in occupational settings.

RESULTS: There were noteworthy commonalities among the approaches described to review and address critical aspects of risk …

Patient Preferences For Ultrasound Soft Sign Disclosure With Prior Negative Cfdna Screening, Disha Patel

Dissertations and Theses (Open Access)

Soft signs are nonstructural fetal anomalies that can be identified by the second-trimester comprehensive ultrasound examination. In isolation, soft signs are insufficient to diagnose chromosome conditions but can adjust an individual's risk for aneuploidy, primarily Down syndrome. In the age of noninvasive cell-free DNA (cfDNA) prenatal screening, which exhibits superior sensitivity and specificity for aneuploidy compared to what can be provided by soft sign risk adjustment, the utility of these soft signs is arguably waning. Thus, this study aimed to establish patient preferences for whether and how soft signs are disclosed in pregnancy to inform recommendations for disclosure. A survey …

Patient Understanding Of Fetal Sex Versus Gender In The Context Of Routine Cell-Free Dna Screening, Mindy Kolodziejski

Dissertations and Theses (Open Access)

Non-invasive prenatal testing (NIPT) is the current standard of care to screen for fetal aneuploidy using cell-free DNA (cfDNA). NIPT screens for sex chromosome aneuploidies (SCAs) and in doing so, can predict fetal chromosomal sex. Despite sex and gender being distinct concepts, many patients refer to NIPT as “the gender test” and elect testing in order to find out predicted fetal sex and assume gender. Our study aimed to evaluate and describe patient understanding of sex and gender in the context of receiving routine prenatal genetics education (PGE) on NIPT. A survey was developed with the goal of assessing patient …

Influential Factors For Disclosing A Tuberous Sclerosis Complex Diagnosis To Romantic Partners, Laura Gorecki

Dissertations and Theses (Open Access)

Tuberous sclerosis complex (TSC) is a highly variable genetic condition characterized by multi-organ tumor predisposition. Due to the heritability, variability, and severity of this condition, individuals with TSC may face unique psychosocial challenges in dating and romantic relationships, specifically related to disclosing their diagnosis to romantic partners. Despite disclosure within romantic relationships being explored in the context of other genetic conditions, this area has not yet been explored in the TSC community who face unique challenges related to physical and mental health, educational performance, and overall quality of life. This study surveyed 117 independent adults with TSC regarding the following …

Inclusion Of Adoption As A Pregnancy Management Option In Prenatal Genetic Counseling Practice, Emma Billings

Dissertations and Theses (Open Access)

Prenatal genetic counselors are essential to providing education, psychosocial support, and guidance on pregnancy options to patients who receive a fetal diagnosis of an anomaly or genetic condition. Therefore, genetic counselors should be well-educated on comprehensive pregnancy management options consisting of parenting, abortion, and adoption. The landscape of adoption education in genetic counseling practice was last characterized in 2010 by Perry and Henry, revealing substantial variability in both the inclusion of adoption-specific education in genetic counseling program (GCP) curricula and the discussion of pregnancy options with patients in prenatal practice. As a result, the authors published a call to action …

Impact Of Genetic Counseling On Patient Empowerment After Diagnosis Of Fetal Anomaly, Carley Brueckner

Dissertations and Theses (Open Access)

Approximately 3-5% of pregnancies are affected by fetal anomalies, often leading to structural and functional differences that impact infant health and mortality. When anomalies are identified on prenatal ultrasound, genetic counseling (GC) and genetic testing may be offered to investigate the potential for a possible syndromic cause. Genetic counselors provide education on the chance for a genetic etiology, available testing options, potential changes in medical intervention related to an identified etiology, and psychosocial counseling and resources. Regardless of a patient’s testing decision, genetic counseling should include psychosocial counseling to support and empower patients in a time of prognostic uncertainty and …

Motivations And Attitudes For Pursuing Anonymous Genetic Testing For Huntington’S Disease, Jordan Steffen

Dissertations and Theses (Open Access)

Huntington’s disease (HD) is a progressive neurodegenerative disorder for which predictive and confirmatory testing is available. However, only a small portion of at-risk individuals complete predictive testing. Concerns of privacy and genetic discrimination have been cited as reasons testing is declined. This leads some to seek anonymous testing, a process in which measures are taken to exclude identifying information, thereby preventing results from being linked to legal names, medical records, or health insurance. Previous research suggests anonymous testing is not widely favored amongst healthcare providers, but patient perspectives have not been described. These studies also precede the implementation of the …

Does Contingent Reward Leadership Enhance Or Diminish Team Creativity? It Depends On Leader (Un-) Predictability, Debjani Ghosh, Martin Buss, Amita Shivhare

Management Faculty Publications

Although prior research has shown that reward provision might sometimes increase creativity, little is known about how leadership that clarifies effort-reward contingencies (i.e., contingent reward leadership) is related to team creativity. Drawing on the theory of learned industriousness, we argue that contingent reward leadership can enhance team knowledge exchange and, in turn, team creative performance. However, we propose that this relationship is moderated by leader unpredictability, which can create uncertainty about resource allocation, thereby undermining the otherwise positive effect of contingent reward leadership. In a two-source, lagged design (three-wave) field study with data from 60 organizational teams, we found a …

Meta-Analytic Investigations Of Team Development Interventions And Effectiveness, Sydney Begerowski

All Dissertations

Team development interventions (TDIs) are evidenced-based best practices that improve performance trajectories of teams. To date, various independent studies have demonstrated the effectiveness of one type of TDI in improving effectiveness, but there has yet to be a cross-intervention assessment. Accordingly, the goal of this dissertation was to explore a subset of TDIs (team charters, team training, team debriefing) from a comparative lens. First, I conducted a series of pairwise meta-analyses across team charters, team training, and team debriefing to establish a TDI-effectiveness relationship. Findings were inconclusive regarding team charters, but suggested that team training and team debriefing significantly improve …

A Mixed Methods Study Of South Carolina Reading Policy On Teacher Knowledge, Matthew Ferguson

All Dissertations

This sequential explanatory mixed methods study examines the impact of the Language Essentials for Teachers of Reading and Spelling (LETRS) professional learning intervention on teacher knowledge within the context of South Carolina's reading policy.

Quantitative analyses of pre- and post-assessment data indicate significant improvements in teacher content knowledge of foundational literacy skills following LETRS training. Descriptive statistics and paired-samples t-tests demonstrate substantial gains in knowledge, particularly in Volume 1 of the LETRS curriculum. The study reveals notable increases in pre- and post-assessment scores, suggesting the effectiveness of LETRS in enhancing teacher expertise.

Qualitative findings from focus groups highlight the positive …

What Do You Want To Be When You Grow Up? An Explanatory Sequential Mixed Methods Study Examining What Influential Factors Guide Rural Middle School Students To Consider A Potential Career Trajectory, Heather Wilks

All Dissertations

This explanatory sequential mixed methods study examines what influences 7th and 8th grade rural middle school students to consider a potential career trajectory. Phase One of the study includes a demographic and career cluster interest survey of 38 participants. Phase Two of the study focused on 23 of the 38 Phase One participants, who were chosen using random sampling. The Phase Two participants were interviewed using a semi-structured approach. They were asked to discuss their career cluster results from Phase One, how they used their surrounding factors and knowledge to conclude, and if they agreed with their results. Findings indicated …

Developing Machine Learning Agency Among Youth: Characterizing Youth Critical Use, Examination, And Production Of Machine Learning Applications, Ibrahim Oluwajoba Adisa

All Dissertations

This study explores how middle school-aged youths at an afterschool center utilized, examined, and produced AI applications for social good with the support of adults and peers. The study employs a qualitative single case study design. It uses thematic analysis and quantitative ethnography methods to analyze data from multiple sources, including field notes, interviews, focus groups, story completions, video recordings, and artifacts. Findings indicated that engaging youths in critical exploration of AI tools enhanced their ability to design interest-based AI applications that provide solutions for healthcare problems, security, and accessibility. Moreover, the computational thinking practices that youth engaged in increased …

Going, Going, Gone: The Influence Of Job And Home Demands And Resources On Emergency Department Nurse Turnover, Jordan Gail Smith

All Dissertations

Nurse turnover, which challenged healthcare organizations even before the pandemic, reached alarming rates across hospitals worldwide during COVID-19. Due to the unprecedented and stressful nature of the pandemic, recent investigations have focused primarily on exploring job demands and nurse turnover intentions. While job demands are critical to understanding turnover, this narrow scope ignores the possible influence of other factors such as job resources and demands and resources external to the work domain. This study utilized archival qualitative data from a longitudinal survey of Emergency Department clinicians to analyze research questions and hypotheses. The first aim of this study was to …

Investigating Bimanual Haptic Exploration With Arm-Support Exoskeletons, Balagopal Raveendranath

All Dissertations

The ability to judge properties like weight and length of hand-held objects is essential in industrial work. Sometimes workers use devices like exoskeletons, which can augment their ability to lift and move heavy objects. Previous studies have investigated the perceptual information available for one-handed weight and length judgments. The current study investigated how blindfolded participants bimanually heft and wield objects to explore haptic information, to perceive object heaviness or length. The study also investigated the effects of using an arm-support exoskeleton (ASE) on the perceived weight of hand-held objects. We empirically tested whether people wield and manipulate objects differently, depending …

A Rhetorical-Sociological Understanding Of Emotion, Amy Boone

All Dissertations

This project presents a rhetorical-sociological understanding of emotion while foregrounding the place and role of language. Born from Sara Ahmed’s work in The Cultural Politics of Emotion, it presents a simplified equation (contact + orientation = emotion) as both a prescriptive and descriptive formula for making sense of human emotional experience. Starting with an exploration of the difficult-to-understand affect system, this dissertation identifies both rhetoric and affect as energies which cannot be understood apart from their traces, the things they move, produce, and become. As a way to get at these often-invisible forces, two trace studies are conducted which explore …

Can I Get A Witness? Employee Reactions To Witnessing Visible Self-Compassion At Work, Sara Krivacek

All Dissertations

Self-compassion is defined as a tripartite process whereby an individual notices their own suffering, feels empathetic concern for oneself, and responds to alleviate or address the suffering. Research on self-compassion has proliferated in the last decade, and a major theme in the literature posits that it is beneficial for the practicing individual. However, less attention is given to the impact of self-compassion expression on other individuals in the workplace – partly because one major assumption is that self-compassion is an internalized process. In this dissertation, I conceptualize self-compassion as a social process and draw from affective events theory to make …

An Exploration Of The Efficacy Of Virtual Agents Within Smartphone Mental Health Applications, Stephanie Six

All Dissertations

The prevalence of depression in the U.S. has increased over the past decade, leading to an all-time-high during the COVID-19 pandemic (WHO, 2022). With this increase, the number of mental health applications (MHealth apps) on virtual e-stores increases in tandem. Despite this expanding number of MHealth apps, few demonstrate a foundation in empirical research. One design factor that may influence usability and effectiveness is the inclusion of virtual agents. Three studies were conducted to investigate users’ preferences for a variety of characteristics associated with virtual agents. In Experiment 1, users completed a single-session, three-stage CBT-based interaction with virtual characters and …

Shift Schedule Justice And Clinician Outcomes: A Quasi-Experimental Approach, Caroline George

All Dissertations

Emergency Physicians (EPs) work in stressful and unpredictable work environments. Due to these factors and the nature of their work scheduling (in shifts), EPs experience heightened levels of adverse work outcomes. As such, it is important for EPs to believe their shift schedule is fair, and for them to have adequate recovery time away from work. The present research examined the effects of Emergency Department leadership approving a 1-hour increase to EP shifts, equating to roughly two fewer shifts per month (8-hour shifts will become 9-hour shifts). As such, EPs should experience more time off from work per month, allowing …

Design And Application Of Smart Systems To Address Analytical Problems, Lucas B. Ayres

All Dissertations

This dissertation is a multidisciplinary effort that integrates low-cost analytical instrumentation, redox chemistry, and artificial intelligence to overcome existing limitations in the fields of wearable sensing technology, Deep Eutectic Solvents (DES), and antioxidant chemistry. The overall goal behind each implemented strategy is to enhance the accuracy, efficiency, and accessibility of analytical processes and technologies. A general overview of the thesis, along with the research outcomes is included in Chapter One. The theoretical framework of this dissertation is presented in Chapter Two. Chapter Three describes the development of a wearable platform (sensor and instrumentation) to rapidly detect (~20 minutes) S. aureus …

Challenges Beyond Addiction: Maternal Experiences With Postpartum Substance Use Disorder Recovery And Perspectives Of Reproductive Healthcare Providers, Leah Holcomb

All Dissertations

Substance use disorders (SUD) impact millions of pregnant and postpartum people in the United States. With the increasing rates of perinatal substance use and the risk of overdose and death during the postpartum period, understanding overall functioning and the needs of postpartum persons is critical for informing interventions to reduce the impact of substance use within the perinatal period. The goal of this research is to explore the needs of postpartum people navigating SUD recovery.

This dissertation investigates postpartum maternal functioning within the context of early SUD recovery, as well as the comfort of reproductive healthcare providers (RHPs) to care …