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Role Of Evolutionarily Conserved G4 Structures In Enhancer-Promotor Interactions, Shahem Alqudah

Honors Theses

Gene regulation is governed by complex networks of interactions between enhancers and promoters, regions of the genome that are typically distant from one another yet functionally linked through chromatin looping. Recent research has revealed the significant role of Gquadruplexes (G4s) in facilitating these interactions. This thesis explores the role of long Gquadruplex regions (LG4s) in enhancer–promoter communication, proposing that these regions mediate physical interactions between enhancers and their target promoters through direct G4:G4 interactions. Using a chromatin conformation capture (EQuIP-seq), electrophoretic mobility shift assays (EMSA), and luciferase reporter assays, the study demonstrates that LG4s may drive gene expression by promoting …

Linear Polydicyclopentadiene Copolymers: Synthesis And Thermal Properties, Connor Lewis

Honors Theses

No abstract provided.

Implementation Of The American College Of Cardiology And American Diabetes Association Clinical Practice Guidelines For Statin Therapy In Reducing Cardiovascular Risk Among Patients With Type 2 Diabetes, Edward Eloy Iruegas

Doctor of Nursing Practice

The incidence of type 2 diabetes has significantly increased over the past decade, making it a risk factor for cardiovascular disease (Banach et al., 2022). Individuals with type 2 diabetes are four times more likely to develop atherosclerotic cardiovascular disease, accounting for up to a 75% mortality rate. Despite this, the risk for atherosclerotic cardiovascular disease remains underestimated and undertreated in this population (Banach et al., 2022). The purpose of this project was to enhance adherence to the American College of Cardiology 2019 and the American Diabetes Association 2023 clinical practice guidelines regarding statin therapy for patients with type …

Attachment, Emotional Experiencing, And Physiological Response During Couple Interaction, Kyla Iverson

All Graduate Theses and Dissertations, Fall 2023 to Present

In this master’s thesis, I conducted a study using data from 63 hetereosexual couples from a previous research study done by Dr. Ryan Seedall. These couples participated in a micro-intervention where each partner discussed personal issues for three to four minutes while the other received guidance on supportive responses, promoting open communication. Using this data, I conducted a coding project studying the relationship between attachment styles and emotional experiencing, specifically how attachment styles intersect with emotional experiences, moment-to-moment feelings, and physiological arousal. This coding project involved utilizing the Emotional Experiencing Scale (EXP) by Klein and colleagues (1986) to observe couple …

Contrastive Representation Learning For Highly Imbalanced Multivariate Time Series With Extreme Instance Strategy, Onur Vural

All Graduate Theses and Dissertations, Fall 2023 to Present

Time series data refers to a sequence of data points collected or recorded at regular time intervals. In many fields including space weather, healthcare, and finance, predicting events from such data is crucial because these predictions can help protect infrastructures, improve healthcare outcomes, and forecast financial trends. However, one challenge in working with time series data is the presence of rare events, which are often underrepresented in the data. This imbalance makes it difficult for traditional prediction methods to provide accurate results, as they tend to focus more on the more frequent events and overlook the rare ones. To tackle …

Disentangling Factors Contributing To Population Performance Of Zion Bighorn Sheep, Ian Montgomery

All Graduate Theses and Dissertations, Fall 2023 to Present

Bighorn sheep populations across the western United States face increasing challenges from habitat loss, disease, and predation. In Zion National Park and surrounding areas, survey-based estimates indicate that the desert bighorn sheep population declined from over 800 individuals in 2018 to fewer than 500 in 2021. Understanding what drives these population changes is critical for effective wildlife management and conservation. This research examined key factors influencing population growth and individual survival to inform strategies for recovery in this bighorn population.

First, we analyzed which vital rates contributed most to population trends by estimating survival and reproduction rates from ground and …

Investigating Stability Of Cone-Derived Hypersonic Waverider Vehicles Via Design Space Exploration, Adam S. Weaver

All Graduate Theses and Dissertations, Fall 2023 to Present

It may come as no surprise that man-made objects flying at 5, 10, or even 25 the speed of sound (termed hypersonic) are difficult to design, inefficient in flight, and expensive to deploy. Most hypersonic vehicles are effectuated in ballistics, which simplify aerodynamic considerations owing to their fixed trajectory. However, maneuverable hypersonic vehicles can revolutionize commercial flight, national defense, and space travel. One candidate for such missions are waverider vehicles. Waverider vehicles cruise on a cushion of air generated by its own shock wave, essentially enjoying extra lift without any extra drag penalties (which are usually inherent to extra …

Development In Comprehensive Onboarding Training And Professional Development For Online Adjunct Faculty, Leslie R. Stover

Doctoral Dissertations and Projects

Hiring online adjunct faculty in higher education continues to grow, encompassing nearly half of the overall faculty population. As four-year institutions rely on the benefits of adjunct faculty, they must also invest in their orientation and continuous development. Existing literature confirms the varied approaches to supporting adjunct faculty, deficiency in coordinated programming, and reveals a lack of understanding in adjunct faculty's perception of training delivered. Using a qualitative phenomenological design, this study explored the gap between the onboarding and professional development an institution provides and the online adjunct faculty’s perception of its effectiveness. The research questions explored the lived experiences …

Phenomenological Study: Exploring The Importance Of The Holy Spirit Experience Among Non-Cessational Church Leaders In South Carolina, Amelia J. Simmons

Doctoral Dissertations and Projects

Over time, many movements have influenced the theological foundations of Western Christianity and culture. For example, modernism has influenced Western culture leading to a rejection of supernaturalism, causing many individuals to overlook the transformative power of the Holy Spirit in personal and social life. Few theological works focus specifically on the Holy Spirit, and what is often proposed lacks a unified synthesis of empirical evidence. The foundation guiding this study is the biblical New Testament, which expresses the importance of the Holy Spirit and how He changes believers into diehards for Christ Jesus. Some church leaders today exhibit reluctance toward …

“I Can Run At Night!”: Using Augmented Reality To Support Nighttime Guided Running For Low-Vision Runners, Yuki Abe, Keisuke Matsushima, Kotaro Hara, Daisuke Sakamoto, Tetsuo Ono

Research Collection School Of Computing and Information Systems

Dark environment challenges low-vision (LV) individuals to engage in running by following sighted guide—a Caller-style guided running—due to insufficient illumination, because it prevents them from using their residual vision to follow the guide and be aware about their environment. We design, develop, and evaluate RunSight, an augmented reality (AR)-based assistive tool to support LV individuals to run at night. RunSight combines see-through HMD and image processing to enhance one’s visual awareness of the surrounding environment (e.g., potential hazard) and visualize the guide’s position with AR-based visualization. To demonstrate RunSight’s efficacy, we conducted a user study with 8 LV runners. The …

Medusa's Metamorphosis: Art, Mythology, And The Changing Perception Of Female Power, Elizabeth Kehr

School of Art, Art History, and Design: Theses and Student Creative Work

The evolution of Medusa’s iconography in ancient Greek art mirrors societal and cultural transformations. As attitudes shifted in relation to gender roles, power relationships, and morality changed, so too did images of the Gorgon. Following the course of development of Medusa’s image allows one to discover details of the thoughts and struggles the ancient Greeks had with concepts of power, womanhood, and monstrosity and otherness. Previous art historical research on Medusa has largely examined her function and evolution of visual depictions from the Archaic monster to Classical ideal. Few, however, have explored how and why these changes may be indicative …

Illustrating Identity: Ethel Reed’S Art Posters And Women's Claims To Public Space In Fin-De-Siècle Boston, Miranda R. Knofczynski

School of Art, Art History, and Design: Theses and Student Creative Work

Much scholarship has uncovered the history of women illustrators during the late nineteenth century. The rebuilding of these lost histories calls for research which theorizes women’s contributions to the burgeoning arts scene of the fin-de-siècle. This thesis will examine the posters Ethel Reed created for different companies during the height of the 1890s poster craze and discuss how she articulated women in public space in them. Reed’s art offers an aestheticized yet feminist visualization of women engaging in leisure activities such as exploring the city, reading, or attending the theatre. Many have described the women in her posters as merely …

Enhancing The Eden Alternative Model With Well Standards: A Case Study Analysis, Mariah Stoner

Architecture Masters of Science Program: Theses

This thesis investigates the potential for improving the Eden Alternative Model, a person-centered approach to elder care that emphasizes creating a homelike environment and meaningful relationships, using WELL Standards, a building certification system focused on enhancing human health and well-being through improvements in environmental quality. Through a mixed-methods approach involving quantitative data analysis and qualitative case studies, this research examines how WELL Standards, which cover aspects such as air quality, water quality, lighting, and thermal comfort, can improve environmental quality and resident satisfaction within the Eden Alternative Model. This research introduces a tailored approach to elder care by combining these …

A Curriculum To Cultivate Whole Musicians: A New Approach To Aural Skills Instructions Promoting Student Success In Other Music Classrooms, Caden J. Hirsch

Glenn Korff School of Music: Dissertations, Theses, Student Creative Work, and Performances

The following thesis is founded on the construction of a new undergraduate aural skills curriculum. While many aural skills methods may exploit some varieties in exercise and assessment formats, this method attends to and prioritizes the advantages of those formats more purposefully, thus being more transparent toward students in their learning and introducing certain agency they may hold in their studies.

Students undergo a 5-semester curriculum in this method, organized into a fundamentals semester, and Aural Skills courses 1, 2, 3, and 4, the last of which is split into two modular options. Students who participate in this curriculum are …

Mediated Dwelling: Reconstructing The Contemporary Home Space, Nicholas Carraher

Masters in Architecture Program: Theses

As online social media platforms become dominant areas for self-expression, professional opportunity, and cultural exchange, the role of typical residential architecture in contemporary society is changing to meet the demands of this visually driven and performative culture. Social media’s emphasis on aesthetic appeal, shareability, and curated authenticity challenges traditional architectural paradigms that prioritize functionality, spatial quality, and privacy. This change coincides with the broader Western cultural shift in ideals and social dynamics of the contemporary user. The home space, a once-private refuge, has been redefined in the age of online social media, where physical space is endlessly curated to align …

Language, Equity, And Power: A Critical Discourse Analysis Of Student Conduct Policies At Unl, Mandi Laib

Department of Educational Administration: Dissertations, Theses, and Student Research

This study conducts a Critical Discourse Analysis of student conduct policies at the University of Nebraska-Lincoln from 1977 to 2003 to examine how language reflects and reinforces institutional power structures. Utilizing Critical Race Theory and Queer Theory, this research investigates how conduct policies have historically marginalized Students of Color, LGBTQ+ students, and those facing economic hardship. Through a deductive coding process, themes such as institutional control, surveillance, and punitive framing were identified across four decades of student handbooks. While there are moments where student rights and restorative justice are acknowledged, these are often overshadowed by dominant discourse that prioritizes compliance …

A Descriptive Study Exploring The Role Church Leaders Have In Maintaining Liberty Within A Free Republic, Rashad R. Gibson

Doctoral Dissertations and Projects

The purpose of this qualitative descriptive study explored the assumptions, perceptions, and understood responsibility of church leaders in New England to maintain liberty and virtue in a free republic. The theory that guided this study is transformational leadership, as it emphasizes morality in both the leader and the follower (Burns, 1978; Northouse, 2015). Within the last six decades, the United States Supreme Court has made rulings to remove from public schools, prayer, general Bible reading, and the Ten Commandments (Abington School District V. Schempp, 374 U.S. 203 (1963); Facts and Case Summary - Engel V. Vitale, 1962; Stone V. Graham, …

Fostering Educator Well-Being To Manage Job-Related Teacher Stress, Jennifer L. Ringelheim

Doctor of Education (Ed.D.)

The job-related expectations for effective classroom instruction expanded beyond teaching academics after the COVID-19 pandemic, which increased job-related teacher stress (Weisling, 2023). Using a convergent mixed-methods design, the researcher of this Improvement Science Dissertation in Practice (ISDiP) identified a problem of practice as the demands of teaching post-COVID-19 on teacher well-being. In Phase 1 of this ISDiP, the researcher conducted end-user consultations, reviewed existing data, completed a root cause analysis, and reviewed scholarly literature to develop a working theory of improvement to manage teacher stress with self-care and regulation strategies. Phase 2 of this ISDiP aimed to understand to what …

The Grizzly, May 1, 2025, Kate Horan, Erin Ewing, Renee Washart, Claudia Tracy, Nathaniel Nerone, Sidney Belleroche, Adam Denn

Ursinus College Grizzly Newspaper, 1978 to Present

The Grizzly Takes On CoSA! • Senior Alumni Award Honorees • A Goodbye • And a Hello! • Repair Cafe • Hillel: A Home for Many • Ursinus College 2024-25 Crossword • Sports Stars Shine at URSPYS • Ursinus Softball Battles Through Ups and Downs

Epistemic Dysfunction In American Politics: The Impact Of Misinformation On Knowledge Acquisition., Megan Crowley

College of Arts & Sciences Senior Theses

Political misinformation has become an increasingly prominent topic of discussion among scholars across disciplines, particularly in the wake of the 2020 American presidential election. Despite growing scholarly interest in this phenomenon, however, contemporary research has yet to examine misinformation alongside traditional epistemological theory. This thesis aims to remedy this gap by synthesizing classical epistemology, journalism and media research, and political science to investigate the impact of misinformation on political knowledge acquisition. To accomplish this goal, the analysis will focus on the justification condition, conceptualized according to both internalist and externalist perspectives. The internalism section will cast misinformation as a form …

Antiproliferative Effects Of Salvia On Breast Cancers., Allison C. Portaro

College of Arts & Sciences Senior Theses

Breast cancer is the most common cancer diagnosed in female adults, with 2.3 million new cases worldwide in 2020. Plants have been used in traditional medicine and are a potential source of pharmaceuticals. One example is the large Lamiaceae (mint) family. The Salvia genus, commonly known as the sages, is the largest genus in Lamiaceae with almost 900 known species. Salvia lyrata (lyre-leaved sage) has a history of Native American medicinal use to treat cancers and other ailments resulting in this plant being referred to as ‘cancer weed.’ Extracts were produced from the leaves of S. lyrata, S. lyrata …

The Effects Of Prenatal Cigarette Smoke Exposure On Developmental Milestones, Megan Jacobs

College of Arts & Sciences Senior Theses

In Kentucky, a reported 12.7% of mothers smoke cigarettes during pregnancy. Nicotine readily crosses the placental and blood-brain barriers, with fetal blood concentrations reaching 15% higher than maternal levels. By stimulating and desensitizing nicotinic acetylcholine receptors in the autonomic nervous system, nicotine disrupts uteroplacental blood flow, potentially altering fetal growth and development.

To investigate the effects of prenatal cigarette smoke exposure (CSE) on developmental milestones, C57Bl6 mice were exposed to either cigarette smoke (CSE, n = 30) or filtered room air (Sham, n = 20) for 3 hours daily from two days before mating until the day before birth. Offspring …

The Publics Of Hannah Arendt And Jürgen Habermas, Andrew Heggie

College of Arts & Sciences Senior Theses

Hannah Arendt’s and Jürgen Habermas’s accounts of the public are notable and important cornerstones in contemporary western political philosophy. This thesis will offer characterizations of Arendt’s account of the public realm in The Human Condition, and Habermas’s account of the public sphere in The Structural Transformation of The Public Realm, comparing and contrasting these accounts to each other in order to highlight the uniqueness of each account; as well the possible contemporary political relevance of these accounts.

A Qualitative Study On Recruiting And Retaining Black, Veteran, In-Service Teachers In Rural Tennessee K-12 Public Schools, Paul Andrew Mcmillan

Ed.D. Dissertations

The purpose of this qualitative, interpretive study was to explore the perceptions of Black, veteran, in-service teachers regarding recruitment and retention strategies in rural Tennessee K-12 public schools. This study addressed significant racial disparities in the Tennessee education system, where the percentage of Black teachers was notably lower than the percentage of Black students, particularly in rural schools. Data were collected from 20 Black, veteran, in-service teachers using questionnaires and semi-structured interviews to examine the factors influencing their decisions to seek employment and remain in rural districts. Analysis of the data identified three key themes related to Research Question 1 …

How Graphene’S Berry Dipole Is Determined By Its Atomic Registry With A Substrate, Hannah K. Isbell

Physics Undergraduate Honors Theses

Since graphene’s discovery in 2004, it has been established as one of the most important materials in recent condensed matter history. Understanding its properties and potential uses has been the subject of intense scientific research around the world. Graphene’s unique physical properties allow it to serve a wide variety of purposes, from its everyday role in the formation of graphite in pencils to its more cutting-edge scientific functions in electronics and energy storage. Gaining a better understanding of graphene’s rich quantum landscape through geometric and topological phenomena, like Berry curvature and Berry dipole, could have significant implications for both theoretical …

A Mixed-Method Examination Of Social Media Influencers’ Source Characteristics In Sponsored Health Campaign Messaging: An Application Of Psychological Reactance Theory, Lauren Pick

Communication (PhD) Dissertations

Social media influencers (SMIs/influencers) are frequently used for marketing and public relations purposes (i.e., influencer marketing), but can be leveraged to avoid resistance to health campaign messages. Guided by psychological reactance theory (PRT), the purpose of this dissertation was to (a) uncover micro-influencer characteristics that mitigate reactance toward sponsored social media posts, (b) investigate whether influencers induce less reactance than non- influencers when disseminating sponsored health content, and (c) experimentally test whether influencer source characteristics mitigate reactance to sponsored health messaging. In Study One, focus groups with Gen Z Instagram users (N = 12) identified SMI use of controlling, “one …

Implications Of Biourbanism On Sustainable Business Strategy, Samuel Walsh

Graduate Theses - Engineering Management

Recently developed for urban planners to view cities through the lens of ecosystems and other complex natural systems, the Biourbanism model is a set of metrics to numerically assess the resilience and sustainability of urban systems. This model focuses on ten factors of urban sustainability, which include categories such as energy, infrastructure, and technology, and is intended to help cities achieve more holistic measures of their ability to realize resilience and sustainability goals. The premise of this Integrated Project is that businesses can also be viewed as complex natural systems. Hence, this project examines case studies to show how implementing …

Isolating The Causes Instead Of The Student: Building Belonging And Connectedness Among And With Students, Cheryl Ann Faga

Doctor of Education (Ed.D.)

Embedded at the heart of the educational system is the teacher-student relationship. This qualitative Improvement Science Dissertation in Practice (ISDiP) examines the impact of the teacher-student relationship on students’ sense of belonging in the classroom and the broader school culture and climate in an urban interdistrict high school magnet program. At the 2022 Association of Middle School Leadership, Houston Kraft, developer of Character Strong, explained that "If we know connection and belonging is a human need, we have to build systems and skills that support the acquisition of and development of connection before students ever feel safe to learn" (Simpson, …

Enhancing The University Of Arkansas' Operations Through Data Science, Aura L. Pinto-Avelar

Data Science Undergraduate Honors Theses

As universities navigate financial constraints and resource allocation challenges, data driven financial analysis has become increasingly important. Universities employ various methods to assess financial efficiency, predict future expenditures, and optimize student credit hour distribution. However, the approaches to financial analysis vary widely, with some institutions leveraging advanced predictive modeling and business intelligence tools, while others rely on traditional budgeting techniques and manual forecasting.

This thesis examines how the University of Arkansas' (“Uark”) financial analysis methods compare to those of other institutions and alternative data-driven approaches. Using four years of financial and student credit hour data, this study evaluates cost trends …

Lucky Charms: Leveraging Consumer Data Analysis For Strategic Decision-Making At General Mills, Katherine Page Thomas

Data Science Undergraduate Honors Theses

This undergraduate thesis examines the application of data analytics in sales strategy and consumer insights from the perspective of a summer internship at General Mills. It gives an overview of the company’s background, industry position, and intern’s role within the sales organization. It outlines the personal learning objectives established before the internship and how they evolved through practical experience.

A central focus of the summer internship was the analysis of consumer demographics within the cereal category to enhance sales performance and optimize retail execution. Using the Data Science Analytics Process as a framework, this thesis details the problem statements, methodologies, …