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Repugnancy Test (Policy) And The Impact Of Colonially Imposed Laws On The Growth Of Nigeria’S Native Justice Systems, Nonso Okeresfoezeke May 2025

Repugnancy Test (Policy) And The Impact Of Colonially Imposed Laws On The Growth Of Nigeria’S Native Justice Systems, Nonso Okeresfoezeke

Journal of African Policy Studies

No abstract provided.


Public Policy And Social Welfare Programs In Zimbabwe: An Evaluation Of Esap, Robert Dibie, Saliwe M. Kawewe May 2025

Public Policy And Social Welfare Programs In Zimbabwe: An Evaluation Of Esap, Robert Dibie, Saliwe M. Kawewe

Journal of African Policy Studies

No abstract provided.


Radiologic And Histologic Findings Of Undifferentiated Sarcoma Treated With Radical Resection, Justina Kasteri, Stefan Johnson, Joseph Hatem, Joel Thompson May 2025

Radiologic And Histologic Findings Of Undifferentiated Sarcoma Treated With Radical Resection, Justina Kasteri, Stefan Johnson, Joseph Hatem, Joel Thompson

Advances in Clinical Medical Research and Healthcare Delivery

Case report of an 89-year-old patient presenting with a nontraumatic painless growing mass on the right thigh. This article presents the diagnostic imaging and histologic microscopic views of the mass following a radical resection. Further discussing the key findings to diagnose undifferentiated sarcomas as well as the clinical management.


Drug-Induced Hypersensitivity Syndrome Resulting In Hepatotoxicity And Epstein-Barr Virus Reactivation Following Initiation Of Levetiracetam, Zechariah Jung, Xavier Zonna, Samuel J. Wlasowicz, Conor Banta, Lawrence Canale, Joseph Bielecki May 2025

Drug-Induced Hypersensitivity Syndrome Resulting In Hepatotoxicity And Epstein-Barr Virus Reactivation Following Initiation Of Levetiracetam, Zechariah Jung, Xavier Zonna, Samuel J. Wlasowicz, Conor Banta, Lawrence Canale, Joseph Bielecki

Advances in Clinical Medical Research and Healthcare Delivery

A 28-year-old male with a past medical history of alcohol abuse had new-onset seizures suspected to be caused by alcohol use. Twelve days after starting levetiracetam for seizure prophylaxis, he began to develop a pruritic rash, darkening of his urine, periods of jaundice, and hot flashes that correlated with the timing of his levetiracetam dosing. He was subsequently found to have lymphocyte-predominant leukocytosis, elevated aminotransferases, and alkaline phosphatase. Following discontinuation of his levetiracetam, he was found to have positive Epstein-Barr virus (EBV) serology suggestive of reactivation. This case demonstrates levetiracetam as a rare cause of drug-induced hypersensitivity syndrome (DIHS) along …


Non-Classical Mullerian Uterine Anomaly: A Case Report, Sandres Aodish, Michelle Chin, Tyler Dobratz, Patrick Swaney, James Zillman May 2025

Non-Classical Mullerian Uterine Anomaly: A Case Report, Sandres Aodish, Michelle Chin, Tyler Dobratz, Patrick Swaney, James Zillman

Advances in Clinical Medical Research and Healthcare Delivery

Congenital uterine anomalies are malformations that occur during female fetal development. The maturation of the paramesonephric ducts (mullerian ducts) is responsible for the formation of the uterus and other reproductive organs. It is within this developmental process that mullerian anomalies occur. Abnormalities of the uterus can be classified as arcuate, septate, bicornuate, unicornuate, and uterine didelphys. Commonly, patients with mullerian anomalies are asymptomatic, however those that are symptomatic often present with fertility difficulties. Asymptomatic anomalies are often discovered incidentally, as was the case with the patient presented in this report. The patient is a 28-year-old G2P1001 39w0d who elected to …


Mystery Of Maha: Hypertension’S Twist Over Cancer’S Shadow, Andrew Takla, Gabriel Vachon, John Hix, Nagesh Jadhav May 2025

Mystery Of Maha: Hypertension’S Twist Over Cancer’S Shadow, Andrew Takla, Gabriel Vachon, John Hix, Nagesh Jadhav

Advances in Clinical Medical Research and Healthcare Delivery

Microangiopathic hemolytic anemia (MAHA) refers to nonimmune hemolysis resulting from the intravascular fragmentation of red blood cells. The etiology of such disorders can range from primary thrombotic microangiopathic syndromes (TMA) to various systemic conditions, posing a diagnostic challenge. Prompt identification requires a sharp clinical assessment to improve outcomes.


Mirizzi Syndrome: A Case Report, Elizabeth Barr, Keng Moua, Kavitha Vemuri May 2025

Mirizzi Syndrome: A Case Report, Elizabeth Barr, Keng Moua, Kavitha Vemuri

Advances in Clinical Medical Research and Healthcare Delivery

Mirizzi syndrome is a rare complication of chronic gallstone disease that occurs when an impacted gallstone at the gallbladder infundibulum or cystic duct causes common extrinsic hepatic or common bile duct obstruction. Contrary to other gallstone pathologies where gallstones affect the respective location in which they are lodged, Mirizzi syndrome is unique in that it is characterized by extrinsic gallstone compression. Chronic gallstone disease most commonly leads to acute cholecystitis, acute cholangitis, or acute pancreatitis. The extrinsic compression of the common hepatic or common bile duct may lead to eventual erosion which increases the risk for a cholecystocholedochal or cholecystohepatic …


Arcanobacterium Haemolyticum Chronic Osteomyelitis And Bacteremia Complicated By Intraosseous Abscess: A Case Report., Edward Lovering, Michelle Bahrain May 2025

Arcanobacterium Haemolyticum Chronic Osteomyelitis And Bacteremia Complicated By Intraosseous Abscess: A Case Report., Edward Lovering, Michelle Bahrain

Journal of Community Hospital Internal Medicine Perspectives

Arcanobacterium haemolyticum is an anaerobic, gram-positive bacillus most commonly associated with non-streptococcal pharyngitis. However, it is a rare cause of systemic infection and bacteremia. In this report, we present the case of a 39-year-old man diagnosed with A. haemolyticum bacteremia secondary to chronic osteomyelitis and an intraosseous abscess.


Rapidly Developing Bilateral Loculated Streptococcus Pyogenes Empyema In An Immunocompetent Adult: A Case Report, Anish K Shrestha, Matthew Dwumah-Agyen, Boniface Mensah, Yvette Yeboah-Kordieh, Marcos A Wolff, Jennifer A Evans May 2025

Rapidly Developing Bilateral Loculated Streptococcus Pyogenes Empyema In An Immunocompetent Adult: A Case Report, Anish K Shrestha, Matthew Dwumah-Agyen, Boniface Mensah, Yvette Yeboah-Kordieh, Marcos A Wolff, Jennifer A Evans

Journal of Community Hospital Internal Medicine Perspectives

Streptococcus pyogenes is a rare cause of empyema, especially in immunocompetent individuals. The organism expresses various virulence factors leading to rapid progression of the disease. We report a case of rapidly progressing bilateral loculated empyema caused by streptococcus pyogenes in an immunocompetent host without additional risk factors.


A Budding Pancreatic Mass: A Review Of Disseminated Blastomycosis, Tina C. L. Phan, Chloe N. Hundman, Neena Thomas-Gosain, Christopher D. Jackson May 2025

A Budding Pancreatic Mass: A Review Of Disseminated Blastomycosis, Tina C. L. Phan, Chloe N. Hundman, Neena Thomas-Gosain, Christopher D. Jackson

Journal of Community Hospital Internal Medicine Perspectives

A 67-year-old male patient presented with anorexia, weight loss, skin masses, and flank pain over the past three months. Imaging revealed a lung mass and a cystic lesion in the pancreatic head. After initial diagnostic work-up and clinical deterioration, broad based budding, seen on pathology, led to a diagnosis of disseminated blastomycosis. After receiving a 14-day course of liposomal amphotericin B followed by itraconazole, the patient showed significant clinical improvement. We reviewed all disseminated blastomycosis cases in the medical literature involving gastrointestinal organs. Although pancreatic involvement is rare, we suggest that it should be suspected in those with a rapidly …


Resolution Of Chronic Urticaria In A Vegan Patient With Vitamin B12 Supplementation: A Case Report, Auda H. Auda, Oluwasegun Shoewu, Ingrid Corredor, Ayrton Bangolo, Mohammad Jurri, John Sotiriadis, Iyad Baker May 2025

Resolution Of Chronic Urticaria In A Vegan Patient With Vitamin B12 Supplementation: A Case Report, Auda H. Auda, Oluwasegun Shoewu, Ingrid Corredor, Ayrton Bangolo, Mohammad Jurri, John Sotiriadis, Iyad Baker

Journal of Community Hospital Internal Medicine Perspectives

Background Chronic urticaria, characterized by persistent hives and pruritus lasting over six weeks, often presents diagnostic and therapeutic challenges. While its etiology is frequently idiopathic, associations with nutritional deficiencies, such as vitamin B12 deficiency, have been observed. Case Presentation A 24-year-old female with no significant medical history presented with chronic, treatment-resistant hives persisting for several years. Comprehensive evaluations, including allergy testing and autoimmune screenings, were unremarkable. Further investigation revealed a significant vitamin B12 deficiency (serum B12 level of 170 pg/mL), attributed to her long-standing vegan diet without supplementation. Initiation of vitamin B12 supplementation led to the gradual resolution of her …


Inferior Wall Stemi In A Young Patient- A Sequela Of Phentermine And Smoking, Nismat Javed, Vikram Itare, Emamuzo Obaro Otobo, Yordano Montesano, Preeti Jadhav, Nassim Krim May 2025

Inferior Wall Stemi In A Young Patient- A Sequela Of Phentermine And Smoking, Nismat Javed, Vikram Itare, Emamuzo Obaro Otobo, Yordano Montesano, Preeti Jadhav, Nassim Krim

Journal of Community Hospital Internal Medicine Perspectives

Amphetamine use is associated with increasing rates of cardiovascular risks, such as pulmonary hypertension, arrhythmias, and atherosclerosis. A 47-year-old woman experienced an inferior MI after taking the weight loss drug phentermine. She presented with chest pain, shortness of breath, and vomiting. Initial examination showed low blood pressure and slow heart rate. Subsequent tests revealed elevated cardiac enzyme levels and ST elevations on EKG. A coronary angiogram showed a blockage in the right coronary artery. She underwent a successful procedure to open the artery. The case highlights the heightened cardiovascular risks associated with amphetamine use, even in individuals without existing heart …


A ‘Fluke’ Diagnosis: Suspecting Fascioliasis As A Rare Cause Of Hepatic Abscess, Tharun Shyam, Rosa Lora, Sharanya Kaushik, Jessica Chung, Monica Ghitan, Christina Coyle May 2025

A ‘Fluke’ Diagnosis: Suspecting Fascioliasis As A Rare Cause Of Hepatic Abscess, Tharun Shyam, Rosa Lora, Sharanya Kaushik, Jessica Chung, Monica Ghitan, Christina Coyle

Journal of Community Hospital Internal Medicine Perspectives

Hepatic abscess is a rare complication of fascioliasis, with fewer than 50 reported cases worldwide. The diagnosis requires a high degree of suspicion and is often identified after extensive investigation leading to delays in treatment. With this case report, we aim to highlight the need for a higher index of suspicion in non endemic regions like the USA, especially in cities with large immigrant populations. Given the ease and success rates of treatment with oral triclabendazole, the morbidity from unnecessary invasive testing and disease burden is preventable with a thorough evaluation and targeted clinical assessment.


Pneumococcal Endocarditis: Historical Insights And Modern Challenges, Dmytro Bohuslavskyi, Mahesh Bhattarai, Hussam Ammar May 2025

Pneumococcal Endocarditis: Historical Insights And Modern Challenges, Dmytro Bohuslavskyi, Mahesh Bhattarai, Hussam Ammar

Journal of Community Hospital Internal Medicine Perspectives

The patient in this case was a 72-year-old female who presented with altered mental status and was ultimately diagnosed with pneumococcal endocarditis. On physical examination, no abnormal cardiac murmurs were detected. This case highlights an important lesson: pneumococcal endocarditis, though rare, is a life-threatening condition with a high mortality rate and should be a top consideration in patients with S. pneumoniae bacteremia, even when the cardiac exam is relatively unremarkable.


Reversible Cerebral Vasoconstriction Syndrome Induced By Sumatriptan: A Case Report And Review Of Literature., Rafi Aibani, Morgan Koontz, James Stephen Harman, Amir Kamran, Khawaja Omar May 2025

Reversible Cerebral Vasoconstriction Syndrome Induced By Sumatriptan: A Case Report And Review Of Literature., Rafi Aibani, Morgan Koontz, James Stephen Harman, Amir Kamran, Khawaja Omar

Journal of Community Hospital Internal Medicine Perspectives

Background

Reversible Cerebral Vasoconstriction Syndrome (RCVS) is characterized by multiple transient cerebral vasoconstrictions that typically resolve within three months, often presenting with sudden thunderclap headaches. Although the cause can be identified in 25% to 60% of cases, RCVS can also occur spontaneously. Common triggers include vasoactive substances and postpartum states, with the latter accounting for 50% to 60% of cases. This report discusses a case of RCVS following sumatriptan use.

Case Report.

A 58-year-old woman with controlled hypertension and obstructive sleep apnea presented with recurrent unilateral pulsating headaches, nausea, and photophobia. Initially diagnosed as migraine, she later developed right …


Post-Myocardial Infarction Associated Ventricular Septal Defect In An Older Female., Nismat Javed, Vikram Itare, Nolberto Bladimir Hernandez, Nisha Ali, Preeti Jadhav May 2025

Post-Myocardial Infarction Associated Ventricular Septal Defect In An Older Female., Nismat Javed, Vikram Itare, Nolberto Bladimir Hernandez, Nisha Ali, Preeti Jadhav

Journal of Community Hospital Internal Medicine Perspectives

Background:

Ventricular septal defect (VSD) is a serious but uncommon complication that can develop 2 days to 2 weeks after a myocardial infarction (MI), particularly if percutaneous coronary intervention (PCI) is delayed.

Case Presentation:

A 91-year-old woman with a history of coronary artery disease had undergone PCI in left anterior descending (LAD) and left circumflex artery (LCX) for a non-ST-elevation myocardial infarction (NSTEMI) 4 weeks prior at another facility, which was complicated by distal wire perforation leading to hemopericardium and the need for pericardiocentesis. She presented with chest pain, and her tests showed ST-segment elevation in leads I, aVL, V2-5, …


Wild-Type Cardiac Amyloidosis Due To Transthyretin Protein — A Review, Mustafa Shehzad, Muhammad Hasan, Dawood Shehzad, Muhammad Shariq Akram, Muhammad Faiq Akram, Dawlat Khan, Maham Maqsood, Mamoon Ahmed, Humna Younis May 2025

Wild-Type Cardiac Amyloidosis Due To Transthyretin Protein — A Review, Mustafa Shehzad, Muhammad Hasan, Dawood Shehzad, Muhammad Shariq Akram, Muhammad Faiq Akram, Dawlat Khan, Maham Maqsood, Mamoon Ahmed, Humna Younis

Journal of Community Hospital Internal Medicine Perspectives

Transthyretin amyloid cardiomyopathy (ATTR-CM) arises from the accumulation of transthyretin amyloid fibrils in the myocardium, a consequence of instability and misfolding in wild-type or variant transthyretin protein. ATTR-CM should be suspected in older heart failure patients with raised myocardial wall thickness and diastolic dysfunction on echocardiography in the absence of hypertension or other known causes. This diagnosis can be further supported with late gadolinium enhancement on Cardiac MRI which indicates raised myocardial extracellular volume (ECV) hinting at the expansion of interstitial space by amyloid deposits. Diagnostic work up starts with blood and urine tests to rule out AL amyloidosis and …


Iron Deficiency—More Than Just Anemia: A Literature Review, Arianna S Moss, Zahra Pakbaz May 2025

Iron Deficiency—More Than Just Anemia: A Literature Review, Arianna S Moss, Zahra Pakbaz

Journal of Community Hospital Internal Medicine Perspectives

Iron deficiency (ID) is a global public health concern, as it can be a prodrome of gastrointestinal (GI) malignancies, exacerbate chronic conditions, and lead to an overall decreased quality of life. Despite being the most prevalent nutritional deficiency, it remains underdiagnosed by many healthcare professionals. Misconceptions regarding the clinical and laboratory manifestations of ID lead to delayed or missed diagnoses, contributing to poor patient outcomes. Though anemia is a commonly known consequence of ID, there are additional consequences that remain underrecognized by the medical community, including vague signs and symptoms, such as fatigue, depression, and abnormalities in white blood cell …


Hollywood And Healthcare: Navigating The Dual Impact Of Movies On Public Health, Fremita Chelsea Fredrick, Anish Kumar Reddy Meda, Mini Virmani, Guntash Kaur, Baltej Singh, Rohit Jain May 2025

Hollywood And Healthcare: Navigating The Dual Impact Of Movies On Public Health, Fremita Chelsea Fredrick, Anish Kumar Reddy Meda, Mini Virmani, Guntash Kaur, Baltej Singh, Rohit Jain

Journal of Community Hospital Internal Medicine Perspectives

Introduction Synonymous with the American film industry, Hollywood wields considerable influence on public health through its vast global reach and engaging media. This paper explores Hollywood's role and its impacts on public health, primarily driven by its portrayal of healthcare services, illnesses, and related beliefs and provides recommendations to improve “education entertainment” for the future. Methods PubMed was searched using keywords such as hollywood, healthcare, medical dramas, health education, smoking, suicide, and many more. Relevant literature up to June 2024 has been examined and summarized, which consisted of 37 articles with data from various clinical trials, meta-analyses, and literature reviews. …


The Ethics Of Insider Trading, Miles Morgan May 2025

The Ethics Of Insider Trading, Miles Morgan

Global Tides

In business ethics, insider trading has gone untouched by scholars, as the consensus is that insider trading is morally indefensible, however, questions have emerged regarding the moral responsibility of insiders. This paper engages with Analyzing Insider Trading from the Perspectives of Utilitarian Ethics and Rights Theory by Robert McGee to evaluate the relationship between applied ethics and insider trading. A satisfactory anti-insider trading account must be able to economically or philosophically explain why insider trading is morally wrong. The assumption that this is impossible may be due to a misunderstanding of how we decide what morality is or how economic …


Responsibility To The Land: Perspectives Of Farmers On Climate Change And Land Transition, Meira A. Smit May 2025

Responsibility To The Land: Perspectives Of Farmers On Climate Change And Land Transition, Meira A. Smit

Environmental Studies Honors Projects

Agriculture is a defining aspect of Minnesota and Wisconsin’s culture and identity, characterized by family farms, rolling hills blanketed with crops, and cows. Interspersed are small scale diversified farms and a growing number of emerging and young farmers. Another cultural mainstay is talking about weather, a ubiquitous conversation of Midwesterners. As weather events such as erratic rainfall, drought, and pest pressure become both more common and volatile, and long-term weather patterns shift from “normal”, it is important to ask farmers what they think about it. Adapting to changes and planning for resilience are what farmers have always done, yet increasing …


Hearing Caste: Dalit Resistance Through Folk Music In West Bengal, India, Antara Bhattacharyay May 2025

Hearing Caste: Dalit Resistance Through Folk Music In West Bengal, India, Antara Bhattacharyay

Music Honors Projects

Caste—a graded structure of hierarchy—has historically shaped identities in South Asia and persists to this day. In opposition, Dalits (caste-marginalized communities) have utilized diverse mediums to communicate their resistance. In this thesis, I analyze the role of music in Bengali Dalit resistance through the work of Dalit singer-songwriter Smritikana Howlader (b. 1960). Based on ethnographic research, I investigate how folk music becomes a mode of Dalit historiography. In particular, I explore how Howlader aims to transcend caste boundaries through song, evoking shared humanity. I argue that Howlader’s performances combat dominant caste discourse and Dalit erasure, furthering Bengali Dalit resistance.


Quantifying Dna Methylation In Response To Drought Stress In Silver Firs (Abies Alba), Julia K. Brandfonbrener May 2025

Quantifying Dna Methylation In Response To Drought Stress In Silver Firs (Abies Alba), Julia K. Brandfonbrener

Biology Honors Projects

As future droughts are expected to increase in duration and severity due to climate change, forest managers may need to evaluate which coniferous species are the most resilient in drought events. Drought stress induces changes in physiology, including decreases in water potential, stomatal closure, pigment degradation, and leaf senescence (Jongdee et al., 2002, Munné-Bosch & Alegre, 2004, Heitholt et al., 1991). These physiological changes are associated with epigenetic regulation of gene expression in response to abiotic stressors (Alongi et al. 2025) and have been highly studied in crop plants and Arabidopsis. This project examines the photosynthetic and epigenetic response …


Adding Libraries To The Equation: Mathematical Sciences’ Underutilization Of Academic Librarians, Jennifer L.C. Burke, Elizabeth C. Novosel, Daniel G. Kipnis, Rasitha R. Jayesekere May 2025

Adding Libraries To The Equation: Mathematical Sciences’ Underutilization Of Academic Librarians, Jennifer L.C. Burke, Elizabeth C. Novosel, Daniel G. Kipnis, Rasitha R. Jayesekere

Libraries Scholarship

Academic librarians do not engage with all disciplinary departments equally. Despite equal or even greater efforts, some departments are less responsive to librarian outreach. One such department is mathematics. To understand mathematics departments’ relationships with their academic librarians, three mathematics librarians created a 20-question survey that was disseminated to mathematics faculty, instructors, and instructional staff in the United States and Canada. Of the 188 survey participants, more than a third reported that they never engage with their librarians, approximately half only do so occasionally, and a mere eight percent of participants collaborated with librarians to provide information literacy instruction (IL) …


Veils Of The Unseen, Shinwoo Song May 2025

Veils Of The Unseen, Shinwoo Song

Art Theses and Dissertations

This thesis explores the dynamic interplay between consciousness and unconsciousness and how this relationship influences visual language in my art practice. My research investigates how unconscious impulses and conscious choices intersect in the creative process, shaping artistic expression and viewer interpretation. I examine how visual art can serve as a medium through which hidden emotional and psychological states, such as memory, desire, and internal conflict, emerge and take form. Rooted in the practice of automatism and influenced by Surrealist strategies, my work engages with theories by Jacques Lacan, particularly his notion of the gaze, and Gilles Deleuze’s concepts of extraction …


A.C.T.S.: Accessing Care For Trafficking Survivors, Stephanie Johnson, Kaitlynn Leffler May 2025

A.C.T.S.: Accessing Care For Trafficking Survivors, Stephanie Johnson, Kaitlynn Leffler

Criminology and Criminal Justice Theses and Dissertations

Human trafficking has been a persistent societal problem with significant costs for states, the nation, and across the world. Victims struggle to recognize that they have endured having been trafficked and society lacks the awareness and understanding that is necessary to help. While many organizations have implemented programs aimed at helping victims escape and recover, victims often remain unaware of what resources are available.

Advancements in technology may allow victims a bridge to connecting with services and could offer assistance to law enforcement and prosecutors who are working to hold trafficking offenders accountable. Many younger victims today feel comfortable using …


On Metric Choice In Dimension Reduction For Fréchet Regression, Abdul Nasah Soale, Congli Ma, Siyu Chen May 2025

On Metric Choice In Dimension Reduction For Fréchet Regression, Abdul Nasah Soale, Congli Ma, Siyu Chen

Faculty Scholarship

Fréchet regression is becoming a mainstay in modern data analysis for analysing non-traditional data types belonging to general metric spaces. This novel regression method is especially useful in the analysis of complex health data such as continuous monitoring and imaging data. Fréchet regression utilises the pairwise distances between the random objects, which makes the choice of metric crucial in the estimation. In this paper, existing dimension reduction methods for Fréchet regression are reviewed, and the effect of metric choice on the estimation of the dimension reduction subspace is explored for the regression between random responses and Euclidean predictors. An extensive …


Predicting Sorption Of Diverse Organic Compounds In Soil-Water Systems: Meta-Analysis, Machine Learning Modeling, And Global Soil Mapping, Jiachun Sun, Kai Zhang, Huichun Zhang May 2025

Predicting Sorption Of Diverse Organic Compounds In Soil-Water Systems: Meta-Analysis, Machine Learning Modeling, And Global Soil Mapping, Jiachun Sun, Kai Zhang, Huichun Zhang

Faculty Scholarship

In recent decades, the environmental detection of various organic compounds (OCs) has highlighted the limitations of conventional soil-water sorption models, which simplify complex experimental conditions and often overlook OCs with polyfunctional and ionizable structures. To address these shortcomings, we compiled a comprehensive soil-water sorption dataset encompassing 20,945 data points for 419 OCs with various functional groups and 1037 different soils. Meta-analysis of the dataset revealed the trends of soil sorption associated with OC substructures, soil properties, and solution conditions. Machine learning models employing the XGBoost algorithm, in conjunction with MACCS fingerprints and experimental conditions, were developed to cover the entire …


Tnf-Α-Driven Changes In Polarized Egf Receptor Trafficking Facilitate Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling From The Apical Surface Of Mdck Epithelial Cells, Syntyche Ngalula, Cathleen R. Carlin May 2025

Tnf-Α-Driven Changes In Polarized Egf Receptor Trafficking Facilitate Phosphatidylinositol 3-Kinase/Protein Kinase B Signaling From The Apical Surface Of Mdck Epithelial Cells, Syntyche Ngalula, Cathleen R. Carlin

Faculty Scholarship

This manuscript describes a novel unconventional secretory pathway that facilitates EGF receptor (EGFR) signaling from apical membranes in polarized epithelial cells responding to immune cell mediators. Epithelial tissues provide a physical barrier between our bodies and the external environment and share an intimate relationship with circulating and local immune cells. Our studies describe an unexpected connection between the proinflammatory cytokine tumor necrosis factor-alpha (TNF-α) and EGFR typically localized to basolateral membranes in polarized epithelial cells. These two molecules sit atop complex biological networks with a long history of shared investigative interest from the vantage point of signaling pathway interactions. We …


Reclaiming Space: Addressing Urban Stratification In Atlanta's Bankhead Neighborhood, Maci J. Sims May 2025

Reclaiming Space: Addressing Urban Stratification In Atlanta's Bankhead Neighborhood, Maci J. Sims

Bachelor of Architecture Theses - 5th Year

Picture Bankhead, Atlanta, a neighborhood woven with Black cultural history, where generations of families have shaped a strong, resilient community. But now, that fabric is fraying. Luxury developments rise where community landmarks once stood, coffee shops replace local staples, and long-time residents are priced out. At the center of this transformation is the Atlanta Beltline, originally envisioned as a unifying greenway, now a powerful catalyst for displacement in neighborhoods like Bankhead. The root of this crisis is not just affordability, but a deep housing imbalance: a polarized system of luxury high-rises and clustered affordable housing, leaving middle-income residents without space …