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Our Little Life: A Novel With Other Archival Texts, José Antonio Villarreal, Juan Velasco-Moreno May 2025

Our Little Life: A Novel With Other Archival Texts, José Antonio Villarreal, Juan Velasco-Moreno

Faculty Book Gallery

Our Little Life is the original title of José Antonio Villarreal’s groundbreaking 1959 novel Pocho, which shaped Mexican-American literature for decades. Pocho narrated the experiences of and challenges to the Mexican-American community in 1930s Silicon Valley through the story of Richard Rubio and his family, ending with the U.S.’s entry into World War II. With this new edition, author and editor Juan Velasco restores Villarreal’s original vision for his novel. Published in cooperation with the Villarreal estate, this edition of Our Little Life is based on archival materials from the Villarreal Special Collection at Santa Clara University.

Our Little Life …


Conversational Theatre Rehearsals For English Language Education, Empowerment, And Healing, Jennifer Schaupp May 2025

Conversational Theatre Rehearsals For English Language Education, Empowerment, And Healing, Jennifer Schaupp

Theses and Dissertations

I set out to examine the history and current structure of the English-learning classroom, with a strong focus on adult learners in community-based classrooms, of immigrants, refugees, and more who arrive and make their home in the U.S. as well those born in the U.S. to multilingual homes. I incorporate elements of therapy and theatre, particularly improvisational comedy and Augusto Boal’s Theatre of the Oppressed, as points of comparison to the teachers and students of the classroom by way of Paulo Freire’s Pedagogy of the Oppressed. I use the concept of rehearsal to compare the three disciplines of psychology, language …


Exploring Sense Of Belonging Among Neurodivergent Students In Higher Education, Mollie Rubinstein May 2025

Exploring Sense Of Belonging Among Neurodivergent Students In Higher Education, Mollie Rubinstein

Theses and Dissertations

Positive academic experiences for university students are hard to come by when non-academic experiences are negative (Gidley et al., 2010; Sandhu et al., 2022; Tinto, 1975). This issue has become increasingly important for neurodivergent students in higher education as more of this population is enrolling in university (Cox et al., 2002; Edwards et al., 2022; Gurbuz et al., 2018; Lubin & Brooks, 2021; Izzo et al., 2008; Mamiseishvili & Koch, 2011; Yssel et al., 2016). The purpose of this study is to listen to neurodivergent student voices to learn about their university experience and sense of belonging. Research questions include: …


Relations Among Racism-Related Stress, Anxiety, Spirituality And Mindfulness In Black Sexual Minority Men, Kainaat Anwar May 2025

Relations Among Racism-Related Stress, Anxiety, Spirituality And Mindfulness In Black Sexual Minority Men, Kainaat Anwar

Theses and Dissertations

Abstract Kainaat Anwar RELATIONS AMONG RACISM-RELATED STRESS, ANXIETY, SPIRITUALITY AND MINDFULNESS IN BLACK SEXUAL MINORITY MEN 2021-2022 Jonathan Mathias Lassiter, Ph.D. Master of Arts in Clinical Psychology Black sexual minority men’s experiences of racism and anxiety have not been documented extensively in the literature. There is also a paucity of research exploring protective factors that can mitigate the effects of racial stress on anxiety in BSMM. Therefore, this study looked at the potential moderating effects of spirituality and mindfulness on the relationship between racism-related stress and anxiety in BSMM. Participants completed measures regarding socio-demographics, racism-related stress, anxiety symptoms, mindfulness and …


Exploring Virtual Group Acceptance And Commitment Therapy Format On Participation Of Parents Of Children With Autism, Abigail Owen May 2025

Exploring Virtual Group Acceptance And Commitment Therapy Format On Participation Of Parents Of Children With Autism, Abigail Owen

Theses and Dissertations

Parents of children with autism spectrum disorder (ASD) and co-occurring challenging behavior (e.g., aggression, self-injury, property destruction) experience higher rates of anxiety, depression, and poor overall well-being. Acceptance and commitment therapy (ACT), which encourages psychological flexibility, is an effective intervention for addressing well-being in this population when presented in various formats. Despite its potential to increase accessibility and improve social connectedness for parents, time commitment may impact parents’ willingness to participate in virtual ACT group interventions. The current study examined parents’ participation in and perceived acceptability of 6 hrs of virtual ACT groups in three different formats: a 6-hr workshop, …


Family, Sex, And Gender, Janet Dean May 2025

Family, Sex, And Gender, Janet Dean

Syllabi

No abstract provided.


Optogenetic Activation Of Cortical Microglia Promotes Neuronal Activity And Pain Hypersensitivity, Min-Hee Yi, Yi Liu, Yong U Liu, Jinkyung Lee, Priyanka Hanumaihgari, Sebastian Parusel, Dale B Bosco, Lingxiao Wang, Jiaying Zheng, Wu Shi, Lattawat Eauchai, Supin Chompoopong, Christine L Hunt, Long-Jun Wu May 2025

Optogenetic Activation Of Cortical Microglia Promotes Neuronal Activity And Pain Hypersensitivity, Min-Hee Yi, Yi Liu, Yong U Liu, Jinkyung Lee, Priyanka Hanumaihgari, Sebastian Parusel, Dale B Bosco, Lingxiao Wang, Jiaying Zheng, Wu Shi, Lattawat Eauchai, Supin Chompoopong, Christine L Hunt, Long-Jun Wu

The Brown Foundation: Institute of Molecular Medicine

Chronic pain following peripheral nerve injury is accompanied by increased neuronal activity in the somatosensory cortex. However, whether and how cortical microglia contribute to these changes is less understood. To this end, we applied an optogenetic strategy to specifically target cortical microglia and investigate their function in behavioral pain sensitization. We found that optogenetic activation of microglia in the primary somatosensory cortex (S1) via red-activated channelrhodopsin (ReaChR) triggered pain hypersensitivity and affective-motivational responses in mice. Remarkably, S1-targeted optogenetic stimulation increased microglial landscape changes and ATP release. In addition, optogenetic stimulation altered the microglial proteomic profile, upregulated neuronal c-Fos expression, and …


The Servicemembers Civil Relief Act Should Be Updated To Recognize Remote Courtroom Appearances, Hon. William G. Montgomery, Hon. Gerald A. Williams May 2025

The Servicemembers Civil Relief Act Should Be Updated To Recognize Remote Courtroom Appearances, Hon. William G. Montgomery, Hon. Gerald A. Williams

Texas A&M Law Review

Allowing military members to continue pending civil litigation so that they can focus their attention on warfighting is sound public policy. Most agree we should protect those “who dropped their affairs to answer their country’s call,” and various federal laws have codified that protection for over a century. But what if the civil matter is com- paratively minor or could otherwise be easily resolved? While the Servicemembers Civil Relief Act (“SCRA”) provides essential protections against harassing civil litigation, it should still pro- vide for the ability of deployed personnel to remotely resolve matters. Virtually every military member can easily be …


Dialing In Or Dialing Out? The Relationship Between State Telemedicine Law And Access To Buprenorphine, Stacey A. Tovino May 2025

Dialing In Or Dialing Out? The Relationship Between State Telemedicine Law And Access To Buprenorphine, Stacey A. Tovino

Texas A&M Law Review

This Article begins by reporting the results of a comprehensive 50-state survey assessing state laws and other state sources governing the telemedicine induction (“tele-induction”) and subsequent telemedicine prescription (“tele-prescription”) of buprenorphine for the treatment of opioid use disorder (“OUD”) following the expiration of the COVID-19 public health emergency (“PHE”). Original, concrete findings include: (1) the glaring patchwork of state law governing the tele-induction and subsequent tele-prescription of buprenorphine for the treatment of OUD in the United States; (2) the variety of primary authorities and secondary sources that house relevant permissions, prohibitions, and affiliated requirements; (3) the number of primary authorities …


The Nitrogen-Vacancy-Nitrogen Color Center: A Ubiquitous Visible And Near-Infrared-Ii Quantum Emitter In Nitrogen-Doped Diamond, Brett C. Johnson, Mitchell O. De Vries, Alexander J. Healey, Marco Capelli, Anjay Manian, Giannis Thalassinos, Amanda N. Abraham, Harini Hapuarachchi, Tingpeng Luo, Vadym N. Mochalin, Jan Jeske, Jared H. Cole, Salvy Russo May 2025

The Nitrogen-Vacancy-Nitrogen Color Center: A Ubiquitous Visible And Near-Infrared-Ii Quantum Emitter In Nitrogen-Doped Diamond, Brett C. Johnson, Mitchell O. De Vries, Alexander J. Healey, Marco Capelli, Anjay Manian, Giannis Thalassinos, Amanda N. Abraham, Harini Hapuarachchi, Tingpeng Luo, Vadym N. Mochalin, Jan Jeske, Jared H. Cole, Salvy Russo

Chemistry Faculty Research & Creative Works

Photoluminescent defects in diamond, such as the nitrogen-vacancy (NV) color center, are at the forefront of emerging optical quantum technologies. Most emit in the visible and near-infrared spectral region below 1000 nm (NIR-I), limiting their applications in photonics, fiber communications, and biology. Here, we show that the nitrogen-vacancy-nitrogen (N2V) center, which emits in the visible and near-infrared-II (NIR-II, 1000-1700 nm), is ubiquitous in as-synthesized and processed nitrogen-doped diamond, ranging from bulk samples to nanoparticles. We demonstrate that N2V is also present in commercially available state-of-the-art NV diamond sensing chips made via chemical vapor deposition (CVD). In high-pressure high-temperature (HPHT) diamonds, …


Mentored Ministry - Two, Danny Roman-Gloro May 2025

Mentored Ministry - Two, Danny Roman-Gloro

Syllabi

No abstract provided.


Seminar In The Book Of Joshua, Lawson Stone May 2025

Seminar In The Book Of Joshua, Lawson Stone

Syllabi

No abstract provided.


Exegesis Of Genesis, Craig Vondergeest May 2025

Exegesis Of Genesis, Craig Vondergeest

Syllabi

No abstract provided.


A Novel Arthroscopic-Assisted Fibular-Based Dual Reconstruction With Popliteus Repair Technique For Posterolateral Corner Injury: A Cadaveric And Functional Anatomic Study, S. Ali Ghasemi, Ahmad Naja, Benjamin C. Murray, Arthur Bartolozzi, Gene Shaffer, James Raphael May 2025

A Novel Arthroscopic-Assisted Fibular-Based Dual Reconstruction With Popliteus Repair Technique For Posterolateral Corner Injury: A Cadaveric And Functional Anatomic Study, S. Ali Ghasemi, Ahmad Naja, Benjamin C. Murray, Arthur Bartolozzi, Gene Shaffer, James Raphael

Einstein Health Papers

The structures of the posterolateral corner (PLC) work together as a single unit to provide both static and dynamic functions to the knee. Multiple techniques have been described for PLC reconstruction, however most of these techniques re-establish the static function of the PLC without addressing dynamic components. The popliteus muscle serves an important role in providing dynamic stability to the PLC, but this function is often not restored in reconstruction techniques. We describe a novel technique for PLC reconstruction that includes popliteus repair, and review the functional anatomy and biomechanics of the PLC. We also confirm the dynamic stabilizing role …


2025 Revised Draft Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc. May 2025

2025 Revised Draft Final Insufficiently Reclaimed Sites Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Solution Of Wave Equation By Linear Regression Artificial Neural Network, Nahdh S. M. Al-Saif, Mahmood A. Shamran, Samah Mohammed Ali, Saad Naji Al-Azzawi May 2025

Solution Of Wave Equation By Linear Regression Artificial Neural Network, Nahdh S. M. Al-Saif, Mahmood A. Shamran, Samah Mohammed Ali, Saad Naji Al-Azzawi

Baghdad Science Journal

Wave partial differential equations are one of the most important topics that model, for example, the wave motion of ground vibrations. Hence, finding approximate solutions to such equations with high accuracy and speed faster than difficult and complex analytical solutions has become possible through the use of artificial intelligence and machine learning methods. This research has three goals. The first is to transform the problem of the initial value of the wave equation into its legal form and find its accurate solution. The second is to write a linear-regression neural network algorithm. The third result is applying this algorithm to …


Student Research Project Engineers Better Cpr Training, Aaron Sanborn May 2025

Student Research Project Engineers Better Cpr Training, Aaron Sanborn

UNH Today Archive

No abstract provided.


American Society Of Hematology/International Society On Thrombosis And Haemostasis 2024 Updated Guidelines For Treatment Of Venous Thromboembolism In Pediatric Patients, Paul Monagle, Muayad Azzam, Rachel Bercovitz, Marisol Betensky, Rukhmi Bhat, Tina Biss, Brian Branchford, Leonardo R. Brandão, Anthony K.C. Chan, Vincent E.S. Faustino, Julie Jaffray, Sophie Jones, Hassan Kawtharany, Bryce A. Kerlin, Nicole Kucine, Riten Kumar, Christoph Male, Marie Claude Pelland-Marcotte, Leslie Raffini, Chittalsinh Raulji, Sarah E. Sartain, Clifford M. Takemoto, Cristina Tarango, C. Heleen Van Ommen, Maria C. Velez, Sara K. Vesely, John Wiernikowski, Suzan Williams, Hope P. Wilson, Et Al May 2025

American Society Of Hematology/International Society On Thrombosis And Haemostasis 2024 Updated Guidelines For Treatment Of Venous Thromboembolism In Pediatric Patients, Paul Monagle, Muayad Azzam, Rachel Bercovitz, Marisol Betensky, Rukhmi Bhat, Tina Biss, Brian Branchford, Leonardo R. Brandão, Anthony K.C. Chan, Vincent E.S. Faustino, Julie Jaffray, Sophie Jones, Hassan Kawtharany, Bryce A. Kerlin, Nicole Kucine, Riten Kumar, Christoph Male, Marie Claude Pelland-Marcotte, Leslie Raffini, Chittalsinh Raulji, Sarah E. Sartain, Clifford M. Takemoto, Cristina Tarango, C. Heleen Van Ommen, Maria C. Velez, Sara K. Vesely, John Wiernikowski, Suzan Williams, Hope P. Wilson, Et Al

School of Medicine Faculty Publications

Background: The American Society of Hematology (ASH) guidelines on treatment of pediatric venous thromboembolism (VTE) were published in 2018. In the last 6 years, there has been a 10-fold increase in the number of children involved in VTE treatment trials. Objective: The ASH Committee on Quality and Guidelines agreed to update the pediatric guidelines in conjunction with the International Society on Thrombosis and Haemostasis (ISTH). These ASH/ISTH evidence-based guidelines are intended to support patients, clinicians, and other health care professionals in the management of pediatric patients with VTE. Methods: ASH/ISTH formed a multidisciplinary guideline panel to minimize potential bias from …


Atrapado En Limbo: Fronteras, Anthropologists, And Translation In Contexts Of The Missing And Unidentified At The México-Us Border, Aliya M. Godoy May 2025

Atrapado En Limbo: Fronteras, Anthropologists, And Translation In Contexts Of The Missing And Unidentified At The México-Us Border, Aliya M. Godoy

LSU Master's Theses

The Missing Migrants Project reports that in the past 11 years, 11,138 missing migrants have been recorded in the Americas, with 6,512 of those migrants situated at the México-United States (US) border (Migration Within the Americas, n.d.). The crisis of missing and unidentified migrants at the México-US border is a topic of great discussion in the field of anthropology, and specifically in discourses of humanitarian forensic anthropological work. This research addresses the crisis at the border, expanding on the scholarship of family agency and language barriers between Spanish-speaking communities and medicolegal actors by investigating the role of anthropologists …


Methods For Joint Modeling Of Longitudinal Omics Data And Time-To-Event Outcomes: Applications To Lysophosphatidylcholines In Connection To Aging And Mortality In The Long Life Family Study, Konstantin G Arbeev, Olivia Bagley, Svetlana V Ukraintseva, Alexander Kulminski, Eric Stallard, Michaela Schwaiger-Haber, Gary J Patti, Yian Gu, Anatoliy I Yashin, Michael A Province May 2025

Methods For Joint Modeling Of Longitudinal Omics Data And Time-To-Event Outcomes: Applications To Lysophosphatidylcholines In Connection To Aging And Mortality In The Long Life Family Study, Konstantin G Arbeev, Olivia Bagley, Svetlana V Ukraintseva, Alexander Kulminski, Eric Stallard, Michaela Schwaiger-Haber, Gary J Patti, Yian Gu, Anatoliy I Yashin, Michael A Province

2020-Current year OA Pubs

Studying the relationships between longitudinal changes in omics variables and event risks requires specific methodologies for joint analyses of longitudinal and time-to-event outcomes. We applied two such approaches (joint models [JM], stochastic process models [SPM]) to longitudinal metabolomics data from the Long Life Family Study, focusing on the understudied associations of longitudinal changes in lysophosphatidylcholines (LPCs) with mortality and aging-related outcomes. We analyzed 23 LPC species, with 5,066 measurements of each in 3,462 participants, 1,245 of whom died during follow-up. JM analyses found that higher levels of the majority of LPC species were associated with lower mortality risks, with the …


Antibiofilm Properties Of 4-Hydroxy-3-Methyl-2-Alkenylquinoline, A Novel Burkholderia-Derived Alkaloid, Ravi Orugunty, Abdelahhad Barbour, Fereshteh Younesi, Michael Glogauer, Nopakorn Hansanant, Ronald Shin, Shi-En Lu, Kevin Cao, Abraham Tenorio, Sigmund J Haidacher, Anthony M Haag, Thomas D Horvath, Leif Smith May 2025

Antibiofilm Properties Of 4-Hydroxy-3-Methyl-2-Alkenylquinoline, A Novel Burkholderia-Derived Alkaloid, Ravi Orugunty, Abdelahhad Barbour, Fereshteh Younesi, Michael Glogauer, Nopakorn Hansanant, Ronald Shin, Shi-En Lu, Kevin Cao, Abraham Tenorio, Sigmund J Haidacher, Anthony M Haag, Thomas D Horvath, Leif Smith

Faculty, Staff and Students Publications

Biofilms are an important colonization mechanism employed by several microbial species to better establish themselves and monopolize the acquisition of resources across different environs. Some bacteria have evolved specialized metabolites that, when secreted, disrupt the formation and stability of biofilms generated by competing heterospecies, providing the producing organism with an ecological advantage. Soil-derived species are probable candidates for the identification of such compounds, given the intense level of competition that occurs within the terrestrial ecosystem. The MS14 strain of Burkholderia contaminans isolated from soil in Mississippi has previously been shown to produce antimicrobial compounds like occidiofungin and ornibactin. In this …


Pelvic Fractures In Pregnancy: Multidisciplinary Management And Outcomes, Kaan Sevgi, Steven Pliskow, Sinan Nazif Aran May 2025

Pelvic Fractures In Pregnancy: Multidisciplinary Management And Outcomes, Kaan Sevgi, Steven Pliskow, Sinan Nazif Aran

Student Publications

Pelvic fractures during pregnancy, though rare, pose significant risks to maternal and fetal health, necessitating a multidisciplinary approach to management. These injuries are predominantly caused by high-energy trauma, such as motor vehicle accidents, and are associated with a high incidence of complications, including maternal hemorrhage, placental abruption, and preterm labor. Advances in diagnostic imaging, such as low-dose CT scans and MRIs, have improved diagnostic accuracy while minimizing fetal exposure to radiation. Similarly, biomechanically tailored surgical interventions and innovative treatment strategies, including minimally invasive fixation techniques, have enhanced maternal survival rates, reaching 95% when multidisciplinary care is implemented. Despite these advancements, …


Perceptions And Experiences Of Kenyan Immigrants On Culturally Appropriate Cancer Health Education In Washington State: A Qualitative Study, Rael Odengo, Patricia Talbert, Joy Anderson May 2025

Perceptions And Experiences Of Kenyan Immigrants On Culturally Appropriate Cancer Health Education In Washington State: A Qualitative Study, Rael Odengo, Patricia Talbert, Joy Anderson

Journal of Social, Behavioral, and Health Sciences

Access to culturally appropriate cancer health education (CACHE), such as cancer information in languages other than English, that considers a group’s cultural beliefs, traditions, values, and practices, is increasingly recognized as a global health communication priority. CACHE is essential for reducing healthcare disparities and improving service accessibility among African immigrants, a rapidly growing demographic in the United States. This study explored the perceptions and experiences of Kenyan immigrants in Washington State regarding CACHE. We used a qualitative descriptive design, with a purposive sample of ten participants from the Kenyan immigrant community in Washington State. The Andersen Behavioral Model of Healthcare …


Prevalence And Determinants Of Poor Glycemic Control In Adult Diabetic Patients In A Nigerian Tertiary Hospital, Jideuma Ikenna Egwim, Hope Igbonagwam, Adanna Vivian Egwim, Hadi Danawi, Ifeoma Ogugua May 2025

Prevalence And Determinants Of Poor Glycemic Control In Adult Diabetic Patients In A Nigerian Tertiary Hospital, Jideuma Ikenna Egwim, Hope Igbonagwam, Adanna Vivian Egwim, Hadi Danawi, Ifeoma Ogugua

Journal of Social, Behavioral, and Health Sciences

Diabetes mellitus (DM) is a significant public health concern globally and in Owerri, southeast Nigeria. The deleterious effects of diabetes have been linked to poor glycemic control. According to the International Diabetes Federation, poor glycemic control is reflected in glycosylated hemoglobin (HbA1c) levels > 7.0%, which are associated with substantial morbidity and mortality. Studies have shown a dramatic rise in diabetic complications in Nigeria, particularly in Owerri. However, evidence is lacking regarding the specific risk factors associated with poor glycemic control among DM patients in Owerri. This study assessed the predictors of poor glycemic control in a hospital setting in Owerri. …


The Uncertainties And Questions Of Care Home Residents, Relatives And Staff As A Basis For Evidence-Based Improvement And Research, Reena Devi, Kirsty Jayne Haunch, Elizabeth Helen Graham, Alys Wyn Griffiths, Gary Hodge, Andrew Clegg, Maria Drummond, Anne Forster, Susie Pearce, Karen Spilsbury, Carl Thompson May 2025

The Uncertainties And Questions Of Care Home Residents, Relatives And Staff As A Basis For Evidence-Based Improvement And Research, Reena Devi, Kirsty Jayne Haunch, Elizabeth Helen Graham, Alys Wyn Griffiths, Gary Hodge, Andrew Clegg, Maria Drummond, Anne Forster, Susie Pearce, Karen Spilsbury, Carl Thompson

School of Nursing and Midwifery

Background: Research in long-term residential care settings (or care homes) for older people should address questions and uncertainties that matter most for those receiving and delivering care. Whether research does this effectively is unclear. In part, because the uncertainties and questions of key stakeholders are unmapped. Objective: To capture and prioritise the uncertainties of older people living in care homes, their relatives and staff. Methods: A three-phase mixed-methods study: (i) gathering uncertainties, (ii) data analysis and (iii) prioritisation. Phase 1 used interviews to gather uncertainties from residents (n = 14), relatives (n = 10) and staff (n = 44). In …


I Would Do Backflips And Move The Earth For A Transformational Leader: Exploring The Complex Role Of Psychological Safety In Teacher Evaluation, Melanie M. Morris May 2025

I Would Do Backflips And Move The Earth For A Transformational Leader: Exploring The Complex Role Of Psychological Safety In Teacher Evaluation, Melanie M. Morris

Doctor of Education (EdD)

Teacher evaluations are intended to promote professional growth, yet when conducted without psychological safety (PS), they often lead to disengagement. PS enables educators to receive constructive feedback and take meaningful steps toward improvement. PS is underexamined in K-12 education, especially in formal evaluations. This gap between what evaluations are meant to support and how they are experienced affects how educators respond to feedback, often working against growth rather than promoting it. This qualitative study examined how transformational leadership (TL) influences psychological safety (PS) and how that sense of safety affects willingness to apply feedback. The study was guided by Affect …


Public Lecture, Telescope Viewing Part Of Scopes Conference At Umn Morris, Communications And Marketing May 2025

Public Lecture, Telescope Viewing Part Of Scopes Conference At Umn Morris, Communications And Marketing

Campus News Archive

No abstract provided.


Progress Towards The Asymmetric De Novo Synthesis Of Tetracyclic Triterpenoids: Cucurbitanes, Lanostanes, And Cardiotonic Steroids, Andrea Rachel Bucknam May 2025

Progress Towards The Asymmetric De Novo Synthesis Of Tetracyclic Triterpenoids: Cucurbitanes, Lanostanes, And Cardiotonic Steroids, Andrea Rachel Bucknam

Dartmouth College Ph.D Dissertations

The complex molecular scaffolds of tetracyclic triterpenoid natural products continue to inspire novel chemical reactions. Steroid-based drugs have contributed significantly to human health in the past century, demonstrating a broad range of therapeutic applications including anti-viral, anti-inflammatory, and anti-cancer activities. However, the efficient and flexible synthesis of tetracyclic triterpenoids remains an unsolved problem. Despite numerous reports of medically relevant bioactivity associated with cucurbitanes, lanostanes, and cardenolides, exploration of their pharmaceutical promise has been limited by a lack of access to molecules bearing their requisite carbon frameworks. Prior to the initiation of my doctoral research, there were no reported syntheses of …


"I'M Strictly T4t": Trans For Trans Connections In The Contemporary, Madi Lou Alexander May 2025

"I'M Strictly T4t": Trans For Trans Connections In The Contemporary, Madi Lou Alexander

Dissertations and Theses

Trans for trans relationships, referred to as "t4t", are a relationship type specific to trans individuals. Linguistically originating from Craigslist personal ad spaces, t4t indicates a trans person seeking out and engaging with another trans person. The scope of relationships under the t4t label are often largely associated with sexuality and dating scenes due to their conception in online cruising spaces. Through qualitative analysis, I assess the range of what t4t relationships are through 30 in-depth interviews with participants identifying as trans. This work moves away from focusing on the deficits of holding a marginalized identity, instead aiming to center …


Candidate Interventions For Integrating Hypertension And Cardiovascular-Kidney-Metabolic Care In Primary Health Settings: Hearts 2.0 Phase 1, Andres Rosende, Mark D Huffman, Et Al. May 2025

Candidate Interventions For Integrating Hypertension And Cardiovascular-Kidney-Metabolic Care In Primary Health Settings: Hearts 2.0 Phase 1, Andres Rosende, Mark D Huffman, Et Al.

2020-Current year OA Pubs

BACKGROUND: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implementation tool, the HEARTS Clinical Pathway, has been adopted by 28 countries. To improve the care of hypertension, diabetes, and chronic kidney disease (CKD), HEARTS 2.0 was developed as a three-phase process to integrate evidence-based interventions into a unified care pathway, ensuring consistency across fragmented guidelines. This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway.

METHODS: First, the coordinating …