Digital Commons Network^™

Snap-Ed Nm Brief, Theresa H. Cruz, Mahtab Soleimani, Belinda E. Vicuna

Reports & Documents

No abstract provided.

Digital Resurrection Of Thonis-Heracleion: Technological Advances In Underwater Archaeology And A Speculative Ai-Driven Reconstruction Methodology, James Hutson, Passent Chahine

Faculty Scholarship

This article synthesizes past archaeological research on the submerged Egyptian city of Thonis-Heracleion, critically reviewing excavations and technological interventions deployed since its rediscovery by Franck Goddio and the IEASM team. Situated approximately 10 meters beneath Aboukir Bay near Alexandria, the city represents a significant nexus of Greek and Egyptian cultural heritage, vividly documented in classical sources such as Herodotus and Strabo. Prior excavations have recovered temple complexes, colossal statues, ritual artifacts, and an extensive array of ancient shipwrecks, mapping only a fraction of the extensive site. These investigations utilized pioneering geophysical methods, including multibeam sonar, side-scan sonar, and photogrammetry, establishing …

Dean's Update, June 2025, Neil W. Schluger

SOM Dean's Research Newsletter

No abstract provided.

The Impact Of Principals’ And Mexican American Parents’ Preset Perspectives On Parental Involvement And What It Means For Student Achievement, Brenda Fouse

Electronic Theses and Dissertations

Parental involvement is crucial to increasing student achievement. However, elementary school principals do not always know how to provide effective parental involvement opportunities, particularly for second-generation Mexican American families. This phenomenological qualitative study was designed to improve the understanding of and describe the lived experiences of second-generation Mexican American families and their relationships with schools. A purposive sample of five second-generation Mexican American parents and five elementary school principals participated in semistructured audio and video interviews. The study offered insight into principals’ mindsets as they provided parental involvement opportunities for the families they serve. The major parental themes identified in …

Experimental Evaluation Of Novel Nano Polymer Hybrid Enhanced Oil Recovery In Carbonate Reservoir, Altamish Ahmed Pakeer

Theses

Innovative enhanced oil recovery (EOR) strategies are needed to unlock additional reserves in heterogeneous, oil-wet carbonate reservoirs. This study evaluates hybrid nano-polymer flooding by integrating silica nanoparticles (SiO₂) and single-walled carbon nanotubes (CNT) with novel HPAM polymers (Sav10 and Sav10 VHM) to optimize wettability alteration, rheological parameters, and recovery mechanisms.

A comprehensive experimental approach was employed, where rheological tests assessed viscosity enhancement under varying shear conditions, and wettability alteration was quantified via contact angle measurements using HPAM-SiO₂, HPAM-CNT, Sav10 VHM-SiO₂, and Sav10 VHM-CNT systems. Core floods were performed in three consecutive phases; waterflooding (baseline), standalone nanoparticle flooding, and hybrid nano-polymer …

Advancing Academic Advising With Knowledge Graphs: Integrating Machine Learning And Llms For Personalized Course Planning, Sara Alshamsi

Theses

Academic advising plays a critical role in helping students make informed decisions, improve academic performance, and successfully navigate their university journey. However, with increasing university enrollment, traditional advising methods often struggle to scale, leading to student frustration and overburdened advisors. Additionally, designing course offerings that match student demand is a complex and error-prone process involving multiple stakeholders. To address these challenges, this thesis proposes an automated, data-driven system for generating personalized academic plans for students. The primary aim of this thesis is to develop a system that reduces students’ dependency on advisors while simultaneously providing accurate estimates of course demand …

Big Data Analytics For Mental Health Education: A New Framework For University-Level Evaluation Under Linguistic Confidence Interval Neutrosophic Numbers, Hong Zhu

Neutrosophic Sets and Systems

No abstract provided.

, Generalized Neutrosophic Sets And Its Application In Ku-Algebras University Of New Mexico, Ramesh Kumar D, Vasu M

Neutrosophic Sets and Systems

No abstract provided.

A Comparative Review Of The Fuzzy, Intuitionistic And Neutrosophic Numbers In Solving Uncertainty Matrix Equations, Myra Suphelea Asmizal, Wan Suhana Wan

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic E-Open Sets In A Neutrosophic Topological Spaces, Thangaraja P, Vadivel A, Bobin A, Thayalan S, John Sundar C, Manivannan P

Neutrosophic Sets and Systems

No abstract provided.

A Novel Approach In Heptapartitioned Neutrosophic Sets With Its Weighted Arithmetic Averaging Operator, Sudharani R, Chitra Devi D, Mahimairaj P, Thirunavukkarasu J, Jeyanthi L, Nagalakshmi T

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Sets And Systems, Vol. 83,2025, Florentin Smarandache, Mohamed Abdel-Basset, Maikel. Leyva Vazquez

Neutrosophic Sets and Systems

No abstract provided.

Vouching For Fair Housing: Landlords’ Duty To Accept Housing Vouchers As Reasonable Accommodations For Handicapped Tenants, Elly M. Lang

Missouri Law Review

Earning enough income to afford housing is challenging. Maintaining a steady job that covers both housing and basic essentials requires significant time and energy. Now, imagine you have a physical disability affecting your mobility. Suddenly, your job options are limited, and your health care costs increase. Now, imagine you suffer from a psychological disability as well. Your health care costs skyrocket because you must pay for medications to alleviate both your physical and psychological disabilities, equipment to assist your mobility, therapy fees, and other essential health care costs. In addition, your already limited job opportunities have again been significantly reduced. …

Removing “Black Marks”: How States Can Preserve Wrongful Birth Suits Without Reliance On “Eugenic” Rhetoric, Paul J. Wuennenberg

Missouri Law Review

“[L]ebensunwertes Leben—Life Unworthy of Life.” Those words, used by the National Socialist (Nazi) Party in Germany to describe people with genetic disorders, ring throughout world history as a moral indictment of the Nazi German state and all those who collaborated with it. Unfortunately, Germany was not alone in its designation of some people as unworthy of life; the United States has also, throughout its history, given the same designation to portions of its population. From Japanese-Americans during the Second World War to people with disabilities in the era of eugenics, the American government has frequently singled out those whom it …

Watersmart Farms - Desalination: Inventory And Analysis, Ela Wendell, Abdulla Rasheed, Sharmina Begum, Vaibhav Patel, Goruck Soubans, John K. Ruprecht

Natural resources commissioned reports

A drying climate means traditional water supply resources of farms in southern Western Australia are frequently unable to meet agricultural production demands. However, extensive, untapped sources of brackish or moderately saline water ( <   20,000mg/L total dissolved solids (TDS) are present in nearly all agricultural areas experiencing water shortages. In response, a small, yet increasing, number of farms have privately financed and installed small-scale desalination units to treat locally sourced, salt-impaired water. This approach not only provides a new source of freshwater to the farm portfolio, but is unaffected by changing climatic and weather conditions. Since the majority of the early adopters of on-farm desalination draw the salt-impaired water from groundwater bores, the technology implementation also mitigates local salinization of agricultural land due to groundwater rise, while decreasing reliance on the heavily subsidized, centralized water supply schemes operated by Water Corporation (WC).

The WaterSmart Farms Desalination (WSFD) project was undertaken to assess the nature and performance of existing, small-scale, on-farm desalination systems, including their economics, sustainability, availability, and weaknesses; and to assess these decentralized systems’ applicability and uncertainties for broader application on farms throughout southern Western Australia. The project was undertaken by three major partners, WA Department of Primary Industries and Region Development (DPIRD), WC, and the Harry Butler …

Clearing Cloudy Or Coloured Water On Farms In Western Australia, Department Of Primary Industries And Regional Development, Western Australia

Natural resources factsheets

Cloudy or coloured water can be a nuisance when used for household purposes, and sometimes be unsuitable for livestock, irrigation, or crop spraying. The following is for general information only, it is recommended that people seek expert advice for treating cloudy or coloured water.

State And Transition Models For Mulga Rangelands Of Western Australia, Alison O'Donnell, Anna E. Richards, Suzanne Prober, Peter-Jon A. Waddell, Sarah Luxton, Ian Watson, Brett Abbott, Philip Thomas, Joshua E. Foster

Natural resources published reports

This report details a collaborative project between the Western Australian Department of Primary Industries and Regional Development and CSIRO that focused on developing State and Transition Models (STMs) for mulga rangelands in Western Australia. The overarching aim of the project was to improve the common understanding of the characteristics and dynamics of mulga rangeland ecosystems and the expected impacts of management. Specifically, the project aimed to collate expert knowledge and monitoring information using a nationally consistent framework to develop quantitative and dynamic STMs. The geographic scope of the project covers the extensive mulga rangelands of Western Australia, particularly the Gascoyne …

I Often Dream Of Trains, Melissa Bellovin

Open Access Theses & Dissertations

This is a collection of stories exploring travel, romantic illusions, motherhood and fairy-tale motifs through a surreal lens.

Sustainable Disposal Of Pecan Shells, Jose Carlos Carrasco

Open Access Theses & Dissertations

Urbanization acceleration has increased the consumption of natural resources and carbon footprint, pushing the need for sustainable development. Even though various construction materials are needed for infrastructure development, the most commonly used material is Ordinary Portland Cement for strength (OPC) and durability, while sand is used as a filler in the mixes prepared with OPC. The main goal of this study is to find a sustainable substitute for sand, which is locally available and currently being placed in landfills. One such material is pecan shells, and a thorough analysis of the literature led us to investigate the possible use of …

Transforming The Future Of Health: Building Learning Health Systems Across The Globe, Sandra Yankah, Robert Saunders, Mark L. Tykocinski, Claudia Salzberg, Jonathan Gonzalez-Smith, Rachel Bonesteel, Cameron Joyce, Charles Kahn, Mark Mcclellan, Eyal Zimlichman

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Health care has faced disruptions over the past 5 years, including a global pandemic, supply chain interruptions, workforce shifts, and the introduction of new artificial intelligence (AI) tools. Health care organizations continue to leverage the learning health system (LHS) concept to adapt to these challenges through iterative feedback loops. The Future of Health (FOH), an international community of over 50 senior health leaders that focuses on shared challenges across international health systems, collaborated with the Duke-Margolis Institute for Health Policy in a consensus-building process with FOH members to identify opportunities for action in an LHS. Key areas for action identified …

Emerging Technologies Of Single-Cell Multi-Omics, Yi June Kim, Koichi Takahashi

Faculty, Staff and Student Publications

The heterogeneity of the hematopoietic system was largely veiled by traditional bulk sequencing methods, which measure the averaged signals from mixed cellular populations. In contrast, single-cell sequencing has enabled the direct measurement of individual signals from each cell, significantly enhancing our ability to unveil such heterogeneity. Building on these advances, numerous single-cell multi-omics techniques have been developed into high-throughput, routinely accessible platforms, delineating the precise relationships among different layers of the central dogma in molecular biology. These technologies have uncovered the intricate landscape of genetic clonality and transcriptional heterogeneity in both normal and malignant hematopoietic systems, highlighting their roles in …

International Expert-Based Consensus Definition, Classification Criteria, And Minimum Data Elements For Osteoradionecrosis Of The Jaw: An Interdisciplinary Modified Delphi Study, Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V Van Dijk, Lisa Van Den Bosch, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nicholas S West, Max J H Witjes, Alex M Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller

Faculty, Staff and Student Publications

Purpose: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy to the head and neck. With >9 published definitions and at least 16 classification systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely underdiagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ.

Methods and materials: The …

Outcomes After Palliative Radiation Therapy In Patients With Symptomatic Locoregionally Advanced Breast Cancer, Luisa E Jacomina, David M Swanson, Melissa P Mitchell, Wendy A Woodward, Benjamin D Smith, Chelain R Goodman, Susie X Sun, Timothy A Yap, Funda Meric-Bernstam, Isidora Y Arzu, Elizabeth S Bloom, Pamela J Schlembach, Eric A Strom, Michael C Stauder, Simona F Shaitelman

Faculty, Staff and Student Publications

Purpose: Symptomatic locoregionally advanced breast cancer (SLABC) can cause troublesome pain or wound complications that negatively impact quality of life. Although palliative radiation therapy (RT) can minimize tumor-related symptoms, how best to tailor RT to achieve the most meaningful and durable response is not well defined.

Methods and materials: This is a single institution, multi-site retrospective review of patients with SLABC treated between 2016 and 2023 with palliative RT to symptomatic disease in the breast, chest wall, and/or regional lymph node basins. Overall survival (OS), locoregional control (LC), clinical and radiographic treatment response, overall pain scores, and treatment-related toxicities were …

Gut Microbiota In Immuno-Oncology: A Practical Guide For Medical Oncologists With A Focus On Antibiotics Stewardship, Arielle Elkrief, Bertrand Routy, Lisa Derosa, Laura Bolte, Jennifer A Wargo, Laurence Zitvogel

Faculty, Staff and Student Publications

The gut microbiota has emerged as a critical determinant of immune checkpoint inhibitor (ICI) efficacy, resistance, and toxicity. Retrospective and prospective studies profiling the taxonomic composition of intestinal microbes of patients treated with ICI have revealed specific gut microbial signatures associated with response. By contrast, dysbiosis, which can be caused by chronic inflammatory processes (such as cancer) or comedications, is a risk factor of resistance to ICI. Recent large-scale meta-analyses have confirmed that antibiotic (ATB) use before or during ICI therapy alters the microbiota repertoire and significantly shortens overall survival, even after adjusting for prognostic factors. These results underscore the …

Association Of Sirt6 Expression With Risk Of Pneumonitis Induced By Radiotherapy In Cancer Patients, Fengyuan Yu, Zheng Gong, Yuan Li, Danial F Naseem, Chen Li, Bingying Zhao, Shanshan Zhang, Rukun Zang, Ailu Wu, Qingxin Han, Shuhui Wu, Hongwei Li, Yipeng Song

Faculty, Staff and Student Publications

Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation-induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a potential biomarker and therapeutic target for RP. This study included 170 patients diagnosed with thoracic tumours, all of whom underwent thoracic RT. RP was evaluated and classified as severe RP (SRP) and lower as non-severe RP (NSRP). Analyses were performed using SPSS version 26.0 and the R. Among 170 patients …

A Gut-On-A-Chip Incorporating Human Faecal Samples And Peristalsis Predicts Responses To Immune Checkpoint Inhibitors For Melanoma, Mattia Ballerini, Serena Galiè, Punit Tyagi, Carlotta Catozzi, Hariam Raji, Angeli D G Macandog, Bianca Ionela Slivinschi, Karol K Kugiejko, Martina Freisa, Paola Occhetta, Jennifer A Wargo, Pier F Ferrucci, Emilia Cocorocchio, Nicola Segata, Andrea Vignati, Andrey Morgun, Michela Deleidi, Teresa Manzo, Marco Rasponi, Luigi Nezi

Faculty, Staff and Student Publications

Patient responses to immune checkpoint inhibitors can be influenced by the gastrointestinal microbiome. Mouse models can be used to study microbiome-host crosstalk, yet their utility is constrained by substantial anatomical, functional, immunological and microbial differences between mice and humans. Here we show that a gut-on-a-chip system mimicking the architecture and functionality of the human intestine by including faecal microbiome and peristaltic-like movements recapitulates microbiome-host interactions and predicts responses to immune checkpoint inhibitors in patients with melanoma. The system is composed of a vascular channel seeded with human microvascular endothelial cells and an intestinal channel with intestinal organoids derived from human …

The Burden Of Burnout: Understanding Its Prevalence And Organizational Drivers In Medical Physics, Deborah Schofield, C Lynn Chevalier, Laurence Court, William Harmsen, Akiva Turner

Faculty, Staff and Student Publications

Background: Burnout is a work-related syndrome characterized by increased levels of emotional exhaustion (EE) and depersonalization (DP) along with decreased levels of personal achievement. In the healthcare setting, higher burnout levels have been associated with negative impacts on personnel, an increased risk of errors, and a decrease in the quality of delivered care.

Purpose: The purpose of this study was to assess the prevalence of burnout among medical physicists working in the United States. Additionally, the impact of personal and organizational features on burnout risk was examined.

Methods: The anonymous survey was distributed to 1962 full members of the American …

A Virtual Wellness Program To Enhance Well-Being For Pediatric Oncology Staff During The Covid-19 Pandemic, Karen M Moody, Maria Chang Swartz, Zachary Gresham, Martha Askins, Laura Cahalan, Amy Heaton, Melissa Melo, Alakh Rajan, Madeline Smith, Priti Tewari, Keyana Williams, Cheng-Han Yang, Rhonda Robert

Faculty, Staff and Student Publications

In response to the COVID-19 global health crisis and mandated social isolation, Pediatric leadership at MD Anderson Children's Cancer Hospital was concerned for the psychological impact on its workforce and encouraged wellness programming. A grassroots wellness taskforce was assembled for the Division of Pediatrics. The task force's primary mission was to promote the well-being of clinicians and non-clinical staff members through a broadly accessible, sustainable, and effective virtual wellness program. Guided by the Stanford Model for Professional Fulfillment, a virtual program entitled, "Weekly Wellness Webex" for Pediatrics staff was launched. Weekly Wellness Webex is a 1-hour live-streamed program with varied …

Multi-Institutional Study On Image Quality For A Novel Cbct Solution On O-Ring Linac, Luis Agulles-Pedrós, R Lee Macdonald, Amanda Jean Cherpak, Nayha Dixit, Lei Dong, Kundan Thind, Boon-Keng Teo, Shiqin Su, Alexander Moncion, James L Robar

Faculty, Staff and Student Publications

INTRODUCTION: This work presents a multi-institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.

METHODS: Phantoms for measuring relative electron density (RED) and image quality were sent to six institutions for imaging on Ethos and Halcyon units equipped with HyperSight CBCT. The imaging protocols included tube potential from 100 to 140 kVp and exposure from 80 to 800 mAs. Imaging performance was evaluated with regard to RED versus Hounsfield units (HU), uniformity, contrast-to-noise ratio (CNR), slice thickness, circular symmetry, modulation transfer …

Functional Vs Structural Cortical Deficit Pattern Biomarkers For Major Depressive Disorder, Peter Kochunov, Bhim M Adhikari, David Keator, Daniel Amen, Si Gao, Demetrio Labate, Yewen Huang, Hussain Syed, Hongjie Ke, Paul M Thompson, Danny J J Wang, Braxton D Mitchell, Jessica A Turner, Theo G M Van Erp, Neda Jahanshad, Yizhou Ma, Xiaoming Du, William Burroughs, Shuo Chen, Tianzhou Ma, Jair C Soares, L Elliot Hong

Faculty, Staff and Student Publications

Importance: Major depressive disorder (MDD) is a severe mental illness characterized more by functional rather than structural brain abnormalities. The pattern of regional homogeneity (ReHo) deficits in MDD may relate to underlying regional hypoperfusion. Capturing this functional deficit pattern provides a brain pattern-based biomarker for MDD that is linked to the underlying pathophysiology.

Objective: To examine whether cortical ReHo patterns provide a replicable biomarker for MDD that is more sensitive than reduced cortical thickness and evaluate whether the ReHo MDD deficit pattern reflects regional cerebral blood flow (RCBF) deficit patterns in MDD and whether a regional vulnerability index (RVI) thus …