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Articles 74581 - 74610 of 1826809
Full-Text Articles in Entire DC Network
Exploring Cultural Capital And Literacy Practices In Chinese Immigrant Families: A Critical Ethnographic Case Study, Yuechen Sun
Exploring Cultural Capital And Literacy Practices In Chinese Immigrant Families: A Critical Ethnographic Case Study, Yuechen Sun
Theses and Dissertations
This dissertation explores the cultural capital and literacy practices of Chinese immigrant families residing in a Southeastern U.S. city. Using an ethnographic case study approach, the research examines two groups of Chinese immigrant parents: those with higher educational backgrounds and those who are restaurant owners. The study investigates how parents’ educational and cultural backgrounds influence their perceptions of and commitments to their children’s education, as well as their home literacy practices. It also explores their understanding of the model minority stereotype and their views on educational equity in the U.S. The findings reveal that both groups of parents value education …
Investigating The Ecology Of The Homeless Court: The Promise Of Quasi-Experimental And Statistical Learning Methods, Dylan Wong
Theses and Dissertations
Interactions with the legal system are a crucial factor in maintaining homelessness. Difficulties in addressing legal issues are barriers to accessing services and finding employment and housing. Across the United States, the homeless court is an emerging legal program that has been developed to break this cycle, but they appear to face numerous capacity and coordination problems. Few empirical and systematic investigations have been conducted on homeless court programs. Further, previous studies of homeless courts focus their process and outcome measures on the priorities of the legal system. An investigation into the ecology, or environmental context, of homeless persons would …
The Digital Forum: A Pedagogical Approach To Teaching College English Composition, Thomas Edward Plichta
The Digital Forum: A Pedagogical Approach To Teaching College English Composition, Thomas Edward Plichta
Theses and Dissertations
This action research study focused on the identification of ways to improve the curriculum of freshman Writing Intensive Seminars using an innovative multimodal pedagogical methodology, the Digital Forum, in addition to formal papers and in-class writing. The research examined a Writing Intensive Seminar with approximately 20 students; There were two Research Questions for the present study. RQ1: How does the incorporation of the Digital Forum as a pedagogical approach in college freshman writing classes influence students' levels of behavioral, cognitive, and emotional engagement? RQ2: How does the incorporation of Digital Forums in freshman English Composition courses affect the quality of …
Impact Of Participation In Extracurricular Activities On Female Students’ Motivation, Noha Ibrahim
Impact Of Participation In Extracurricular Activities On Female Students’ Motivation, Noha Ibrahim
Theses and Dissertations
This study investigated the impact of extracurricular activities (ECAs) on academic motivation among female high school students at a semi-governmental international school in the UAE. It addressed three research questions: (1) the effect of ECA participation on academic motivation, (2) students’ perceptions of how these activities influence their motivation, and (3) teachers’ perspectives on their impact. I conducted this action research in a school of 4,500 K-12 students predominantly local and from high-income backgrounds with an international teaching staff. Participants included grade 11 and 12 female students (ages 16–18) enrolled in one of four clubs (Reading, International, Sports, and Art) …
Increasing Professional School Counseling Advocacy Skills For The Practicing Secondary School Counselor, Beverly Denise Mccullough
Increasing Professional School Counseling Advocacy Skills For The Practicing Secondary School Counselor, Beverly Denise Mccullough
Theses and Dissertations
This problem of practice addresses increasing Professional School Counselor (PSC) advocacy skills for the practicing secondary school counselor. Improvement science is the framework used to help solve this problem. The PSC improvement team consisted of a team of seven licensed professional school counselors, all with career experience in the secondary school setting. The team began their work with the goal of understanding the current system by participating in an initial empathy interview. Immediately after the empathy interview was concluded, each committee member completed an initial assessment of the School Counselor Self Advocacy Questionnaire (SCSAQ) to be used as an initial …
Structure-Activity Relationships Of Isothiourea And Silicon Phthalocyanine Catalysts, Christian J. Harrison
Structure-Activity Relationships Of Isothiourea And Silicon Phthalocyanine Catalysts, Christian J. Harrison
Theses and Dissertations
Efficient organic synthesis often relies on improving catalyst designs and investigating reaction mechanisms to accomplish feats such as high stereoselectivity, low catalyst loadings, and performing sustainable chemistry. Within the field of organocatalysis, intermolecular interactions between a catalyst and a substrate are a large contributing factor to the control of a reaction, including rate and selectivity. Investigating mechanisms can provide information on the type of intermolecular interactions occurring in the reaction, aiding future reaction and catalyst development. This dissertation will explore two recent projects and how probing intermolecular interactions through simple modifications provides information useful for new catalyst designs and properties. …
Development Of Teacher Leader Identities In Stem Teacher Leader Programs: Key Experiences From The Perspectives Of Program Developers And Program Completers, Paula Adams
Theses and Dissertations
The purpose of this qualitative case study was to add to the understanding of attributes of a STEM teacher leader project that contribute to the growth of STEM teacher leader identity. Single case study design was employed to explore key experiences in a collaborative Science Technology Engineering and Math teacher leader project and to explore how those experiences enhanced the teacher leader identity of participants. This research includes seven programs from six universities across the United States. The perceptions of two subunits, program developers and program completers, were considered. Data collection began with a document review which included initial university …
Sensing Others, Alissa Reed
Sensing Others, Alissa Reed
Theses and Dissertations
In this project, I notice how we listen and respond to animals, both through marine bioacoustics studies and rhetorical theory, and consider how we might develop new ways of noticing and interacting with animals. I hold together rhetorical theory, marine bioacoustics studies, and my observations nest sitting sea turtles to see what kind of multispecies ethic emerges from messy encounters with nonhuman others – specifically, with sea turtles nesting on the beaches of the Outer Banks in the Summer of 2020. By confronting the unavoidable moments of indecision, and even possible violence, inherent to encounters with nonhumans others, even and …
Regression With Atypical Data: Measurement Error, Periodicity, And Non-Normality, Nicholas W. Woolsey
Regression With Atypical Data: Measurement Error, Periodicity, And Non-Normality, Nicholas W. Woolsey
Theses and Dissertations
Regression is a ubiquitous and fundamental method that can be found in any ele- mentary statistics course. The simplicity and self evidently useful nature of linear regression beguiles a non-negligible portion of researchers into disrespecting assump- tions required by these models, namely in terms of accuracy of covariates and the underlying nature of the data. This disregard can at best lead to meaningless results and at worse cause significant misunderstandings in scientific pursuit.
In this dissertation we strive propose remedies to violations of specific assump- tions. Namely the assumptions that covariates are either observed without measure- ment error or they …
Naqbu: Cosmological Undercurrents In Sumer And Akkad, Fiona Eirene Andrews
Naqbu: Cosmological Undercurrents In Sumer And Akkad, Fiona Eirene Andrews
Theses and Dissertations
The concepts of primordial incomprehensibility, ordered creation, and the liminal chaos between them, form a foundational framework in Mesopotamian intellectual culture. The distinctive ways in which these concepts manifest in Sumero-Akkadian cultures suggest a systematic cosmological substructure — characterized by the paradoxical, cyclical, and co-creative relationships between forces such as Infinity and measure, generation and destruction, and definition and obscurity — that remains insufficiently examined in current scholarship. Drawing from diverse corpus of Mesopotamian creative works, Kabbalistic exegesis, and post-modern scholarship, this thesis seeks to elucidate the essential dynamics within that substructure. By proposing a semiotic hermeneutical strategy attuned to …
Camp In The Kitchen: Feminism And Craft In Liza Lou's Beaded Worlds, Aurora X. Bell
Camp In The Kitchen: Feminism And Craft In Liza Lou's Beaded Worlds, Aurora X. Bell
Theses and Dissertations
Kitchen (1991–96) was the first major work of art by American artist Liza Lou. It is an installation of a life-size kitchen in which every surface and object is covered in glass beads. Kitchen, which Lou refers to as a monument to women’s unsung domestic labor, received considerable critical attention and drew the artist into ongoing conversations around the relationship between “fine art” and “craft” and about the role of feminism in the art of the 1990s. In contemporary interviews, however, Lou expressed discomfort with the label of “craft” as well as with feminist art that she considered “didactic.” …
On A Conjecture On Covering Systems And An Irreducibility Question On Sparse 0,1-Polynomials, Alexandros Kalogirou
On A Conjecture On Covering Systems And An Irreducibility Question On Sparse 0,1-Polynomials, Alexandros Kalogirou
Theses and Dissertations
In 1952, H. Davenport posed the problem of determining a condition on the minimum modulus $m_0$ in a finite distinct covering system that would imply that the sum of the reciprocals of the moduli in the covering system is bounded away from 1. In 1973, P.~Erd\H os and J.~Selfridge indicated that they believed that $m_0$ > 4 would suffice. We provide a proof that this is the case in Chapter 2. Chapters 3 and 4 are dedicated to showing that $0,1$-polynomials of high degree and few terms are irreducible with high probability. Formally, let $k\in\mathbb{N}$ and $F(x)=1+\sum_{i=1}^kx^{n_i}$, where $ 0
In Vivo Analysis Of Fe-S Cluster Assembly And Iron Homeostasis In Escherichia Coli, Dexter Mclaurin Reasons
In Vivo Analysis Of Fe-S Cluster Assembly And Iron Homeostasis In Escherichia Coli, Dexter Mclaurin Reasons
Theses and Dissertations
Iron-sulfur (Fe-S) clusters are an essential cofactor for a wide range of cellular processes, and their assembly and storage require tight regulation.
In Escherichia coli (E. coli), there are two pathways of Fe-S cluster assembly, the Isc and the Suf pathways. The Isc pathway is used under good growth conditions, and the Suf pathway is used under iron starvation and oxidative stress conditions. Once the cluster has been assembled on the scaffold protein of either pathway, it is transferred to Fe-S cluster trafficking proteins. In E. coli, the monothiol glutaredoxin GrxD and the BolA-type proteins BolA and IbaG …
Some Likelihood-Based Methods For Clustering Functional Data, Tong Shan
Some Likelihood-Based Methods For Clustering Functional Data, Tong Shan
Theses and Dissertations
The analysis of functional data is an increasingly relevant part of statistics. The exploratory data analytic method of cluster analysis plays a very important role in different fields. Over the years, researchers have developed many clustering approaches, striving to achieve more accurate and efficient clustering. In Chapter 1, we aim to improve the accuracy of our outcome when clustering functional data. To achieve this goal, we use a predictive likelihood function which serves as an objective function to optimize in order to determine the most appropriate clusters. To optimize the objective function over the space of clustering partitions, we produce …
Clusters In The Storm: Regional Economic Specialization Before And After Hurricane Harvey, Gwyneth King Waddington
Clusters In The Storm: Regional Economic Specialization Before And After Hurricane Harvey, Gwyneth King Waddington
Theses and Dissertations
In recent years, large-scale disaster events have dominated headlines. As the world faces an increasing number of such disasters, it is crucial to understand their impacts beyond immediate monetary losses. Disasters not only directly impact individuals and businesses but may also reshape the spatial patterns of the regional economy. Through a case study of Hurricane Harvey in Texas and Louisiana, this study examines how disaster events influence regional economic specialization patterns and contribute to uneven impacts across economic supersectors and geographies. Expanding on previous methodologies, this study incorporates temporal analysis tools to identify and investigate case studies of economic change. …
Microstructure And Defects Of Aa6061 In The Laser Powder Bed Fusion Additive Manufacturing, Sivaji Karna
Microstructure And Defects Of Aa6061 In The Laser Powder Bed Fusion Additive Manufacturing, Sivaji Karna
Theses and Dissertations
AA6061 is a widely used aluminum alloy known for its excellent thermal conductivity, strength, and corrosion resistance. However, its application in Laser Powder Bed Fusion (LPBF) additive manufacturing is restricted by solidification cracking and porosity. This study examines defect formation, microstructural evolution, and precipitate behavior in AA6061 processed under various LPBF conditions, including room temperature and heated substrates (500°C), as well as pulsed wave laser configurations. Microstructural characterization was conducted using optical microscopy, scanning electron microscopy (SEM) with energy dispersive X-ray spectroscopy (EDS) and electron backscatter diffraction (EBSD), and transmission electron microscopy (TEM).
A maximum relative density of 99.17% was …
A Spatial Scan Statistic For Group Testing Data, Vincent Onyame
A Spatial Scan Statistic For Group Testing Data, Vincent Onyame
Theses and Dissertations
Group testing involves pooling specimens from multiple individuals and offers an efficient means to surveil low-prevalence pathogens, but poses challenges for spatial cluster detection when only pooled results are observed. In this thesis, we develop a spatial scan statistic tailored to group-testing data with variable pool sizes. The statistic compares a null hypothesis of a homogeneous infection rate across all clusters to an alternative hypothesis that infection probabilities differ inside and outside a candidate cluster, with both models fitted by maximum likelihood estimation. We approximate the null distribution of the maximum likelihood ratio test via Monte Carlo simulation.
Through a …
Investigating Mechanisms And Day-Level Factors That Influence Children’S 24-Hour Movement Behaviors, Hannah Parker
Investigating Mechanisms And Day-Level Factors That Influence Children’S 24-Hour Movement Behaviors, Hannah Parker
Theses and Dissertations
Twenty-four hour movement behaviors (i.e., physical activity (PA), screen time (ST), and sleep) are associated with health outcomes, chronic disease (obesity, type 2 diabetes), and mortality. Most literature evaluating children’s 24-hour movement behaviors has focused on static person-level demographic information such as age or biological sex. Relatively less work has examined the variable factors that change day to day, such as environment or context. The Structured Days Hypothesis (SDH) suggests that when children are in structured environments, they have healthier movement behaviors compared to less structured environments where children have more discretionary time to engage in obesogenic behaviors. Besides school/childcare, …
Causal Neuro-Symbolic Artificial Intelligence: Synergy Between Neuro-Symbolic And Causal Artificial Intelligence, Utkarshani Jaimini
Causal Neuro-Symbolic Artificial Intelligence: Synergy Between Neuro-Symbolic And Causal Artificial Intelligence, Utkarshani Jaimini
Theses and Dissertations
Understanding and reasoning about cause and effect is innate to human cognition. In everyday life, humans continuously engage in causal reasoning and hypothetical retrospection to make decisions, plan actions, and interpret events. This cognitive ability allows us to ask questions such as: “What caused this situation?”, “What will happen if I take this action?”, or “What would have happened had I chosen differently?” This intuitive capacity to form mental models of the world, infer causal relationships, and reason about alternative scenarios, particularly counterfactuals, is central to our intelligence and adaptability. In contrast, current machine learning (ML) and artificial intelligence (AI) …
The Other Side Of Trusting: The Implications Of Vulnerability As A Core Component Of Organizational Relationships, Sam Dylan Strizver
The Other Side Of Trusting: The Implications Of Vulnerability As A Core Component Of Organizational Relationships, Sam Dylan Strizver
Theses and Dissertations
Trusting behavior—discretionary risk-taking with another party—is the primary means of facilitating productive workplace relationships (Zand, 1979; Mayer, Davis, & Schoorman, 1995). Yet, little empirical evidence exists to explain what happens after employees engage in trusting behavior, but before outcomes materialize—otherwise termed the “vulnerability phase” (Ballinger, Schoorman, & Sharma, 2024: 2). To address this neglect, I develop a theoretical framework that positions vulnerability as a core psychological state within the trust process, shaped by trustors’ cognitive appraisals of risk severity and uncertainty. Drawing from research on stress and well-being, the framework also identifies coping as a key response to vulnerability, moderated …
Hearing The Unheard: Creating A Brave Space To Analyze The Experiences Of Men Of Color In Student Service Roles And Their Mental Health Challenges Within Higher Education, Calvin Maurice Joyner
Hearing The Unheard: Creating A Brave Space To Analyze The Experiences Of Men Of Color In Student Service Roles And Their Mental Health Challenges Within Higher Education, Calvin Maurice Joyner
Theses and Dissertations
This study analyzed the experiences of five men of color in student service roles dealing with mental health stressors, such as discrimination, workplace burnout, tokenism, and low morale. To highlight their experiences, a brave space was utilized as an intervention. The following questions were examined and answered within this qualitative, action research study: (1) What are the experiences of men of color with mental health challenges in student service roles? (2) How do mental health problems affect the personal and professional lives of men of color in student service roles? (3) How do the brave spaces impact the mental health …
A Neuro-Symbolic Ai Approach To Scene Understanding In Autonomous Systems, Ruwan Tharanga Wickramarachchige Don
A Neuro-Symbolic Ai Approach To Scene Understanding In Autonomous Systems, Ruwan Tharanga Wickramarachchige Don
Theses and Dissertations
Effectively understanding scenes requires a unified representation of scene data and background knowledge. A neuro-symbolic AI approach to scene understanding leverages such a unified representation to enable advanced expression, inference, and labeling of scenes, improving the perception of autonomous systems.
Scene understanding remains a central challenge in the machine perception of autonomous systems. It requires the integration of multiple sources of information, background knowledge, and heterogeneous sensor data to perceive, interpret, and reason about both physical and semantic aspects of dynamic environments. Current approaches to scene understanding primarily rely on computer vision and deep learning models that operate directly on …
The Influence Of Sex Education On Sexual Behaviors From Adolescence To Young Adulthood In South Carolina, Megan Elizabeth Austin
The Influence Of Sex Education On Sexual Behaviors From Adolescence To Young Adulthood In South Carolina, Megan Elizabeth Austin
Theses and Dissertations
Sex education in South Carolina (SC) is known to be limited, which may influence adolescent sexual behaviors, leading to a higher likelihood of lower ages of sexual initiation, more sexual partners, and more experiences of sexual violence. These behaviors are associated with many negative health outcomes.
A political content analysis of bills, laws, and educational standards provides insight to changes in political discourse around sex education from when the Comprehensive Health Education Act (CHEA) was passed in 1988 until 2024. A variable created through this analysis is used along with SC Youth Risk Behavior Survey data to assess changes in …
Beyond Entertainment: Unveiling Digital Platform Strategic Implications For International Business Growth Of Individual Entrepreneurs, Hoik Kim
Theses and Dissertations
This dissertation examines how digital identity, comprising visual, psychological, and strategic components, impacts entrepreneurial success on global digital platforms. Rather than treating identity as a static or aesthetic trait, this study conceptualizes it as a dynamic and strategic construct shaped by audience perception, algorithmic systems, and institutional environments. The research is structured into three empirical studies. The first explores how facial visibility and social media engagement affect monetization on YouTube, considering the international context. The second study empirically investigates how a biometric cue influences entrepreneurial performance on digital platforms and interprets the results through the lens of social psychological perspectives. …
Robust Photogrammetric Scalp Morphology Estimation For Functional Optical Neuroimaging, Abigail L Magee, Calamity Svoboda, Tessa G George, Alvin A Agato, Edward J Richter, Joseph P Culver, Adam T Eggebrecht
Robust Photogrammetric Scalp Morphology Estimation For Functional Optical Neuroimaging, Abigail L Magee, Calamity Svoboda, Tessa G George, Alvin A Agato, Edward J Richter, Joseph P Culver, Adam T Eggebrecht
2020-Current year OA Pubs
SIGNIFICANCE: Optical functional neuroimaging relies upon accurate anatomical models to provide optimal data registration and image reconstruction.
AIM: We establish and validate a robust photogrammetric algorithm for scalp morphology that utilizes 3-dimensional (3D) imaging with a photogrammetric cap to provide individualized scalp morphology estimation through hair in the absence of magnetic resonance imaging (MRI).
APPROACH: The scalp morphology estimation uses a flexible, neoprene cap and 3D-printed photogrammetric modules with fiducials. We create a sparse scalp sampling and align the MNI152 atlas to generate the scalp morphology estimation. We used the international 10 to 20 electroencephalogram positions for alignment and calculated …
Military Inhalational Exposures Outside The Theater Of Conflict And Chronic Respiratory Symptoms, Andrew Timmons, Anna M Korpak, Nicholas L Smith, Karen S Nakayama, Coleen P Baird, Paul Ciminera, Farrah Kheradmand, Vincent S Fan, Jaime E Hart, Petros Koutrakis, Ware Glenn Kuschner, Octavian C Ioachimescu, Michael Jerrett, Philippe R Montgrain, Susan P Proctor, Christine H Wendt, Cherry Wongtrakool, Emily S Wan, Paul D Blanc, Carrie A Redlich
Military Inhalational Exposures Outside The Theater Of Conflict And Chronic Respiratory Symptoms, Andrew Timmons, Anna M Korpak, Nicholas L Smith, Karen S Nakayama, Coleen P Baird, Paul Ciminera, Farrah Kheradmand, Vincent S Fan, Jaime E Hart, Petros Koutrakis, Ware Glenn Kuschner, Octavian C Ioachimescu, Michael Jerrett, Philippe R Montgrain, Susan P Proctor, Christine H Wendt, Cherry Wongtrakool, Emily S Wan, Paul D Blanc, Carrie A Redlich
Faculty, Staff and Students Publications
Importance: Deployment to Afghanistan and Southwest Asia has been associated with adverse respiratory health outcomes. However, the impact of inhalational exposures (eg, vapor, dust, gas, fumes), which are known correlates of reduced lung function and future chronic lung disease, during military service time outside this deployment period has not been assessed.
Objective: To assess military inhalational exposures during nonwartime routine activities and their associations with chronic respiratory symptoms.
Design, setting, and participants: This cross-sectional study used data from the US Department of Veterans Affairs Service and Health Among Deployed Veterans study. US veterans who served between October 7, 2001, and …
Figo Position Statement: Gamete Donations, Jaideep Malhotra, Suchitra Pandit, Carlos Salazar, Alex Vidaeff, Rafal Zadykowicz, M Louise Hull, Nikhil Purandare
Figo Position Statement: Gamete Donations, Jaideep Malhotra, Suchitra Pandit, Carlos Salazar, Alex Vidaeff, Rafal Zadykowicz, M Louise Hull, Nikhil Purandare
Faculty, Staff and Students Publications
Gamete donation has become a crucial part of Assisted Reproductive Technologies (ARTs), providing hope to individuals, including those who may have no other option for parenthood. This process comes with a wide range of ethical, medical, and legal challenges that need to be carefully addressed to protect the well-being and rights of all parties involved: donors, recipients, and offspring. Navigating these complexities requires strict ethical standards, robust regulatory frameworks, and international collaboration. By standardizing these, the field of gamete donation can continue to develop while ensuring that all parties are well informed and safeguarded. This paper explores the ethical concerns …
Microbial Biosensor For Sensing And Treatment Of Intestinal Inflammation, Elena Musteata, Martin V Douglas, Walter J Chazin, Eric P Skaar, Jeffrey J Tabor, Robert A Britton
Microbial Biosensor For Sensing And Treatment Of Intestinal Inflammation, Elena Musteata, Martin V Douglas, Walter J Chazin, Eric P Skaar, Jeffrey J Tabor, Robert A Britton
Faculty, Staff and Students Publications
Synthetic biology has enabled the development of biosensors to detect intestinal inflammation, yet few target the clinically validated biomarker of intestinal inflammation calprotectin with both diagnostic and therapeutic capabilities. Here, an optimized calprotectin biosensor is presented that leverages a zinc uptake regulator (Zur) controlled promoter coupled with a memory circuit to detect and record intestinal inflammation in vivo. The level of biosensor activation strongly correlates with calprotectin levels in the colon of two independent mouse models of colitis. Coupling of the biosensor with the production of the anti-inflammatory cytokine IL10 allowed for the resolution of chemically induced colitis, demonstrating the …
Unfolding The Mystery Of Autoimmunity: The Environmental Determinants Of Diabetes In The Young (Teddy) Study, Ezio Bonifacio, Helena Elding Larsson, Patricia Gesualdo, William Hagopian, Michael J Haller, Heikki Hyöty, Randi Johnson, Richard Mcindoe, Eoin Mckinney, Jessica Melin, Åke Lernmark, Richard E Lloyd, Kristian F Lynch, Jill M Norris, Stephen S Rich, Roswith Roth, Desmond Schatz, Jorma Toppari, Eric Triplett, Kendra Vehik, Suvi M Virtanen, Anette-G Ziegler, Beena Akolkar, Jeffrey P Krischer, Teddy Study Group
Unfolding The Mystery Of Autoimmunity: The Environmental Determinants Of Diabetes In The Young (Teddy) Study, Ezio Bonifacio, Helena Elding Larsson, Patricia Gesualdo, William Hagopian, Michael J Haller, Heikki Hyöty, Randi Johnson, Richard Mcindoe, Eoin Mckinney, Jessica Melin, Åke Lernmark, Richard E Lloyd, Kristian F Lynch, Jill M Norris, Stephen S Rich, Roswith Roth, Desmond Schatz, Jorma Toppari, Eric Triplett, Kendra Vehik, Suvi M Virtanen, Anette-G Ziegler, Beena Akolkar, Jeffrey P Krischer, Teddy Study Group
Faculty, Staff and Students Publications
In 2025, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health celebrates 75 years of leadership in diabetes research. The NIDDK serves people of the U.S. affected by or at risk for many chronic diseases, including diabetes and other endocrine, metabolic, and digestive disorders, by funding innovative research to develop better treatment and prevention and a cure for these conditions. Autoimmunity that leads to type 1 diabetes or celiac disease or thyroid autoimmunity affects 1 in 20 children and adolescents in the U.S. While treatments are available, prevention of these common autoimmune …
Cardiac Rhythm Devices In Heart Failure With Reduced Ejection Fraction – Role, Timing, And Optimal Use In Contemporary Practice European Journal Of Heart Failure Expert Consensus Document, Andrea M Russo, Gianluigi Savarese, Michael Böhm, Loreena Hill, Koichiro Kinugawa, Naoki Sato, William T Abraham, Antoni Bayes-Genis, Alexandre Mebazaa, Giuseppe M C Rosano, Shelley Zieroth, Cecilia Linde, Javed Butler
Cardiac Rhythm Devices In Heart Failure With Reduced Ejection Fraction – Role, Timing, And Optimal Use In Contemporary Practice European Journal Of Heart Failure Expert Consensus Document, Andrea M Russo, Gianluigi Savarese, Michael Böhm, Loreena Hill, Koichiro Kinugawa, Naoki Sato, William T Abraham, Antoni Bayes-Genis, Alexandre Mebazaa, Giuseppe M C Rosano, Shelley Zieroth, Cecilia Linde, Javed Butler
Faculty, Staff and Students Publications
Guidelines for management of heart failure with reduced ejection fraction (HFrEF) emphasize personalized care, patient engagement, and shared decision-making. Medications and cardiac rhythm management (CRM) devices are recommended with a high level of evidence. However, there are significant disparities: patients who could benefit from devices are frequently referred too late or not at all. Misconceptions about device therapy and the notion that the needs of patients (especially the prevention of sudden cardiac death) can now be met by expanding drug therapies may play a role in these disparities. This state-of-the-art review is produced by members of the DIRECT HF initiative, …