Digital Commons Network^™

Diagnostic Accuracy Of Screening Tools For Depression And Anxiety In Cervical Dystonia, Brian D Berman, Florence Ching-Fen Chang, Jeanne Feuerstein, Victor Fung, Gamze Kilic Berkmen, Irene A Malaty, Claire Maciver, Scott A Norris, Kathryn J Peall, Joel S Perlmutter, Sarah Pirio Richardson, Laura J Wright, Zahra Goodarzi, Hyder A Jinnah

Faculty, Staff and Students Publications

Introduction: Despite their high prevalence and impact, depression and anxiety are not routinely screened for, and accuracy of screening procedures is unknown in adult-onset dystonia. We evaluated accuracy parameters of selected self-rated scales for depression and anxiety in patients with idiopathic cervical dystonia (CD).

Methods: Two-hundred-and-ten patients with idiopathic CD were recruited from 10 movement disorders centers from the US, Canada, Australia, and UK. At the end of each botulinum toxin cycle, participants were administered the Adult Standard Mini-International Neuropsychiatric Interview (MINI) as reference standard for depression and anxiety. Participants completed 8 self-administered index instruments (2 for depression, 2 for …

The Experience Of Codependency In Young Adult Romantic Relationships, Amanda S. Soares

Undergraduate Theses and Capstone Projects

This qualitative study used Interpretative Phenomenological Analysis (IPA) to explore the lived experiences of codependency among four young adults (ages 21–24) who had recently exited a codependent romantic relationship. Through in-depth interviews, themes around emotional enmeshment, identity loss, boundary erosion, emotional suppression, and healing were found. Findings indicate that early attachment patterns, trauma, and socialization intersect with emotional vulnerability and self-worth to create conditions ripe for codependent dynamics. Participants describe both the psychological toll of these relationships and the personal growth that followed. These insights contribute to the limited literature on young adult codependency and may inform prevention and intervention …

Real-World Continuous Smartwatch-Based User Authentication, N. Al-Naffakh, N. Clarke, F. Li, P. Haskell-Dowland

School of Engineering, Computing and Mathematics

User authentication is often regarded as the “gatekeeper” of cyber security. It has, however, long suffered from significant usability issues that have resulted in research focussing upon frictionless and transparent biometric approaches. Activity-based user authentication—a technique that authenticates a user by what they are physically doing at a specific point in time has attracted significant attention, particularly due to the increasing popularity of smartwatches. This research aims to overcome limitations in prior work by exploring the viability of the approach in real-world conditions. The study presents two principal experiments, one focused upon a constrained environment to provide a control and …

Where Should The Cancer Control Interventions Target: A Geospatial Hotspot Analysis For Major Cancer Mortality 2018 To 2022 In The United States, Chongliang Luo, Saira Khan, Liyan Jin, Aimee S James, Graham A Colditz, Bettina F Drake

2020-Current year OA Pubs

BACKGROUND: Identifying changes in geographic disparities of cancer mortality reveals locations where cancer prevention and control efforts should be focused/targeted. We use recent cancer surveillance data to demonstrate the geographic disparity of major cancer mortality rates in the United States and its shift compared with previous data.

METHODS: This cross-sectional study used the 2018 to 2022 county-level mortality rates of colorectal, lung, breast, and prostate cancers from the Centers for Disease Control mortality data. Counties with suppressed death counts were imputed by spatial regression models. Getis-Ord Gi* statistics were used to evaluate the spatial clustering of county mortality. Identified hotspot …

Evaluation Of Internally Cooled Radiofrequency Ablation Targeting Multiple Shoulder Nerves For Chronic Shoulder Pain Relief And Function Restoration: A Prospective Study, Mitsukuni Yoshida, Peter K Park, Loc V Thang

2020-Current year OA Pubs

OBJECTIVE: Shoulder pain is a prevalent musculoskeletal disorder, affecting up to 70% of adults over their lifetimes. Recently, radiofrequency ablation (RFA) has gained attention as a treatment for joint pain. This study aims to evaluate the efficacy of internally cooled RFA (icRFA) in alleviating shoulder pain and improving both qualitative and quantitative measures of shoulder function.

DESIGN: Prospective cohort study.

SUBJECTS: Patients with chronic shoulder pain (n = 35) who responded positively to diagnostic blocks of the suprascapular nerve (SSN), axillary nerve (AN), and lateral pectoral nerve (LPN).

METHODS: Patients underwent icRFA targeting the SSN, AN, and LPN. Treatment response …

Performance Of Stool Xpert Mtb/Rif Ultra For Detection Of Mycobacterium Tuberculosis Among Adults Living With Hiv: A Multicentre, Prospective Diagnostic Study, Alexander Kay, Joachim Kikoyo Nsubuga, Carlos Fernández-Escobar, Nosisa Shiba, Lucia Carratalá-Castro, Derrick Semugenze, Patricia Mwachan, Shilzia Munguambe, Joanna Ehrlich, Elisa Lopez-Varela, Andrew R Dinardo, Frank Cobelens, Christoph Lange, Moses Joloba, Anna M Mandalakas, Willy Ssengooba, Alberto L García-Basteiro

Faculty, Staff and Students Publications

Background: When people living with HIV develop pulmonary tuberculosis, it often manifests without detectable acid-fast bacilli on sputum microscopy. We aimed to assess the diagnostic accuracy of stool Xpert MTB/RIF Ultra (hereafter, Ultra) for Mycobacterium tuberculosis detection among adults with HIV.

Methods: This multicentre, prospective diagnostic accuracy study was done in outpatient and inpatient health centres in Eswatini, Mozambique, and Uganda. We enrolled adults aged 15 years and older with HIV with presumptive tuberculosis. We evaluated the diagnostic accuracy of stool Ultra using the simple one-step processing method against a composite microbiological reference standard (CMRS) including three WHO-recommended tuberculosis diagnostic …

The Effect Of An Interdisciplinary Project On Students’ Understandings Of Mathematical Interdisciplinarity: A Qualitative Action Research Study, Jaime Krause

Theses and Dissertations

The siloed nature of education has likely caused some high school students to not recognize the interdisciplinary nature of mathematics, leading them to misunderstand its relationship to other subject areas. A misunderstanding of mathematical interdisciplinarity can cause issues when these students approach interdisciplinary problems later in life. The purpose of this study was to observe, investigate, and analyze the ways in which students understand mathematical interdisciplinarity following a collaborative and interdisciplinary project. I implemented a descriptive qualitative action research approach to determine how a collaborative interdisciplinary project on NASA technology in a high school mathematics course affects students’ understandings of …

Examining Coping, Individual Resilience, And Family Resilience As Strengths-Based Factors For Lgbtq+ Individuals, Elizabeth Moriarty Combs

Theses and Dissertations

Lesbian, Gay, Bisexual, Transgender, Queer/Questioning, and More (LGBTQ+) individuals are part of a diverse and complex community that has unique considerations regarding physical and mental health. While there is ongoing health equity research regarding LGBTQ+ individuals, the focus is often on health disparities. A strengths-based approach to helping LGBTQ+ individuals through research and other avenues may be beneficial. This multi-manuscript dissertation includes two studies that explored the current literature on strengths-based factors such as coping, individual resilience, and family resilience within LGBTQ+ individuals, as well as determined the feasibility of utilizing these factors to assist LGBTQ+ individuals with health and …

An Efficient Detection And Deep Clustering Based Pipeline For Reliable Rodent Ultrasonic Vocalization Analysis, Sabah S. Anis

Theses and Dissertations

Ultrasonic vocalizations (USVs) are critical for understanding rodents' emotional states and social behaviors. However, manual analysis of USVs is time-consuming, subjective, and prone to errors. This thesis presents an automated pipeline that addresses these challenges by performing efficient USV detection and clustering. The proposed approach significantly reduces the time and effort needed to analyze USV data while improving accuracy and reproducibility.

To address this gap, we introduce ContourUSV, a five-step pipeline for USV detection. First, it begins with generating spectrograms from audio recordings, which are then pre-processed to enhance the contrast between USVs and background noise. Key steps include median …

Exploring Cultural Capital And Literacy Practices In Chinese Immigrant Families: A Critical Ethnographic Case Study, Yuechen Sun

Theses and Dissertations

This dissertation explores the cultural capital and literacy practices of Chinese immigrant families residing in a Southeastern U.S. city. Using an ethnographic case study approach, the research examines two groups of Chinese immigrant parents: those with higher educational backgrounds and those who are restaurant owners. The study investigates how parents’ educational and cultural backgrounds influence their perceptions of and commitments to their children’s education, as well as their home literacy practices. It also explores their understanding of the model minority stereotype and their views on educational equity in the U.S. The findings reveal that both groups of parents value education …

Investigating The Ecology Of The Homeless Court: The Promise Of Quasi-Experimental And Statistical Learning Methods, Dylan Wong

Theses and Dissertations

Interactions with the legal system are a crucial factor in maintaining homelessness. Difficulties in addressing legal issues are barriers to accessing services and finding employment and housing. Across the United States, the homeless court is an emerging legal program that has been developed to break this cycle, but they appear to face numerous capacity and coordination problems. Few empirical and systematic investigations have been conducted on homeless court programs. Further, previous studies of homeless courts focus their process and outcome measures on the priorities of the legal system. An investigation into the ecology, or environmental context, of homeless persons would …

The Digital Forum: A Pedagogical Approach To Teaching College English Composition, Thomas Edward Plichta

Theses and Dissertations

This action research study focused on the identification of ways to improve the curriculum of freshman Writing Intensive Seminars using an innovative multimodal pedagogical methodology, the Digital Forum, in addition to formal papers and in-class writing. The research examined a Writing Intensive Seminar with approximately 20 students; There were two Research Questions for the present study. RQ1: How does the incorporation of the Digital Forum as a pedagogical approach in college freshman writing classes influence students' levels of behavioral, cognitive, and emotional engagement? RQ2: How does the incorporation of Digital Forums in freshman English Composition courses affect the quality of …

Impact Of Participation In Extracurricular Activities On Female Students’ Motivation, Noha Ibrahim

Theses and Dissertations

This study investigated the impact of extracurricular activities (ECAs) on academic motivation among female high school students at a semi-governmental international school in the UAE. It addressed three research questions: (1) the effect of ECA participation on academic motivation, (2) students’ perceptions of how these activities influence their motivation, and (3) teachers’ perspectives on their impact. I conducted this action research in a school of 4,500 K-12 students predominantly local and from high-income backgrounds with an international teaching staff. Participants included grade 11 and 12 female students (ages 16–18) enrolled in one of four clubs (Reading, International, Sports, and Art) …

Increasing Professional School Counseling Advocacy Skills For The Practicing Secondary School Counselor, Beverly Denise Mccullough

Theses and Dissertations

This problem of practice addresses increasing Professional School Counselor (PSC) advocacy skills for the practicing secondary school counselor. Improvement science is the framework used to help solve this problem. The PSC improvement team consisted of a team of seven licensed professional school counselors, all with career experience in the secondary school setting. The team began their work with the goal of understanding the current system by participating in an initial empathy interview. Immediately after the empathy interview was concluded, each committee member completed an initial assessment of the School Counselor Self Advocacy Questionnaire (SCSAQ) to be used as an initial …

Structure-Activity Relationships Of Isothiourea And Silicon Phthalocyanine Catalysts, Christian J. Harrison

Theses and Dissertations

Efficient organic synthesis often relies on improving catalyst designs and investigating reaction mechanisms to accomplish feats such as high stereoselectivity, low catalyst loadings, and performing sustainable chemistry. Within the field of organocatalysis, intermolecular interactions between a catalyst and a substrate are a large contributing factor to the control of a reaction, including rate and selectivity. Investigating mechanisms can provide information on the type of intermolecular interactions occurring in the reaction, aiding future reaction and catalyst development. This dissertation will explore two recent projects and how probing intermolecular interactions through simple modifications provides information useful for new catalyst designs and properties. …

Development Of Teacher Leader Identities In Stem Teacher Leader Programs: Key Experiences From The Perspectives Of Program Developers And Program Completers, Paula Adams

Theses and Dissertations

The purpose of this qualitative case study was to add to the understanding of attributes of a STEM teacher leader project that contribute to the growth of STEM teacher leader identity. Single case study design was employed to explore key experiences in a collaborative Science Technology Engineering and Math teacher leader project and to explore how those experiences enhanced the teacher leader identity of participants. This research includes seven programs from six universities across the United States. The perceptions of two subunits, program developers and program completers, were considered. Data collection began with a document review which included initial university …

Sensing Others, Alissa Reed

Theses and Dissertations

In this project, I notice how we listen and respond to animals, both through marine bioacoustics studies and rhetorical theory, and consider how we might develop new ways of noticing and interacting with animals. I hold together rhetorical theory, marine bioacoustics studies, and my observations nest sitting sea turtles to see what kind of multispecies ethic emerges from messy encounters with nonhuman others – specifically, with sea turtles nesting on the beaches of the Outer Banks in the Summer of 2020. By confronting the unavoidable moments of indecision, and even possible violence, inherent to encounters with nonhumans others, even and …

Regression With Atypical Data: Measurement Error, Periodicity, And Non-Normality, Nicholas W. Woolsey

Theses and Dissertations

Regression is a ubiquitous and fundamental method that can be found in any ele- mentary statistics course. The simplicity and self evidently useful nature of linear regression beguiles a non-negligible portion of researchers into disrespecting assump- tions required by these models, namely in terms of accuracy of covariates and the underlying nature of the data. This disregard can at best lead to meaningless results and at worse cause significant misunderstandings in scientific pursuit.

In this dissertation we strive propose remedies to violations of specific assump- tions. Namely the assumptions that covariates are either observed without measure- ment error or they …

Naqbu: Cosmological Undercurrents In Sumer And Akkad, Fiona Eirene Andrews

Theses and Dissertations

The concepts of primordial incomprehensibility, ordered creation, and the liminal chaos between them, form a foundational framework in Mesopotamian intellectual culture. The distinctive ways in which these concepts manifest in Sumero-Akkadian cultures suggest a systematic cosmological substructure — characterized by the paradoxical, cyclical, and co-creative relationships between forces such as Infinity and measure, generation and destruction, and definition and obscurity — that remains insufficiently examined in current scholarship. Drawing from diverse corpus of Mesopotamian creative works, Kabbalistic exegesis, and post-modern scholarship, this thesis seeks to elucidate the essential dynamics within that substructure. By proposing a semiotic hermeneutical strategy attuned to …

Camp In The Kitchen: Feminism And Craft In Liza Lou's Beaded Worlds, Aurora X. Bell

Theses and Dissertations

Kitchen (1991–96) was the first major work of art by American artist Liza Lou. It is an installation of a life-size kitchen in which every surface and object is covered in glass beads. Kitchen, which Lou refers to as a monument to women’s unsung domestic labor, received considerable critical attention and drew the artist into ongoing conversations around the relationship between “fine art” and “craft” and about the role of feminism in the art of the 1990s. In contemporary interviews, however, Lou expressed discomfort with the label of “craft” as well as with feminist art that she considered “didactic.” …

On A Conjecture On Covering Systems And An Irreducibility Question On Sparse 0,1-Polynomials, Alexandros Kalogirou

Theses and Dissertations

In 1952, H. Davenport posed the problem of determining a condition on the minimum modulus $m_0$ in a finite distinct covering system that would imply that the sum of the reciprocals of the moduli in the covering system is bounded away from 1. In 1973, P.~Erd\H os and J.~Selfridge indicated that they believed that $m_0$ > 4 would suffice. We provide a proof that this is the case in Chapter 2. Chapters 3 and 4 are dedicated to showing that $0,1$-polynomials of high degree and few terms are irreducible with high probability. Formally, let $k\in\mathbb{N}$ and $F(x)=1+\sum_{i=1}^kx^{n_i}$, where $ 0

In Vivo Analysis Of Fe-S Cluster Assembly And Iron Homeostasis In Escherichia Coli, Dexter Mclaurin Reasons

Theses and Dissertations

Iron-sulfur (Fe-S) clusters are an essential cofactor for a wide range of cellular processes, and their assembly and storage require tight regulation.

In Escherichia coli (E. coli), there are two pathways of Fe-S cluster assembly, the Isc and the Suf pathways. The Isc pathway is used under good growth conditions, and the Suf pathway is used under iron starvation and oxidative stress conditions. Once the cluster has been assembled on the scaffold protein of either pathway, it is transferred to Fe-S cluster trafficking proteins. In E. coli, the monothiol glutaredoxin GrxD and the BolA-type proteins BolA and IbaG …

Some Likelihood-Based Methods For Clustering Functional Data, Tong Shan

Theses and Dissertations

The analysis of functional data is an increasingly relevant part of statistics. The exploratory data analytic method of cluster analysis plays a very important role in different fields. Over the years, researchers have developed many clustering approaches, striving to achieve more accurate and efficient clustering. In Chapter 1, we aim to improve the accuracy of our outcome when clustering functional data. To achieve this goal, we use a predictive likelihood function which serves as an objective function to optimize in order to determine the most appropriate clusters. To optimize the objective function over the space of clustering partitions, we produce …

Clusters In The Storm: Regional Economic Specialization Before And After Hurricane Harvey, Gwyneth King Waddington

Theses and Dissertations

In recent years, large-scale disaster events have dominated headlines. As the world faces an increasing number of such disasters, it is crucial to understand their impacts beyond immediate monetary losses. Disasters not only directly impact individuals and businesses but may also reshape the spatial patterns of the regional economy. Through a case study of Hurricane Harvey in Texas and Louisiana, this study examines how disaster events influence regional economic specialization patterns and contribute to uneven impacts across economic supersectors and geographies. Expanding on previous methodologies, this study incorporates temporal analysis tools to identify and investigate case studies of economic change. …

Microstructure And Defects Of Aa6061 In The Laser Powder Bed Fusion Additive Manufacturing, Sivaji Karna

Theses and Dissertations

AA6061 is a widely used aluminum alloy known for its excellent thermal conductivity, strength, and corrosion resistance. However, its application in Laser Powder Bed Fusion (LPBF) additive manufacturing is restricted by solidification cracking and porosity. This study examines defect formation, microstructural evolution, and precipitate behavior in AA6061 processed under various LPBF conditions, including room temperature and heated substrates (500°C), as well as pulsed wave laser configurations. Microstructural characterization was conducted using optical microscopy, scanning electron microscopy (SEM) with energy dispersive X-ray spectroscopy (EDS) and electron backscatter diffraction (EBSD), and transmission electron microscopy (TEM).

A maximum relative density of 99.17% was …

A Spatial Scan Statistic For Group Testing Data, Vincent Onyame

Theses and Dissertations

Group testing involves pooling specimens from multiple individuals and offers an efficient means to surveil low-prevalence pathogens, but poses challenges for spatial cluster detection when only pooled results are observed. In this thesis, we develop a spatial scan statistic tailored to group-testing data with variable pool sizes. The statistic compares a null hypothesis of a homogeneous infection rate across all clusters to an alternative hypothesis that infection probabilities differ inside and outside a candidate cluster, with both models fitted by maximum likelihood estimation. We approximate the null distribution of the maximum likelihood ratio test via Monte Carlo simulation.

Through a …

Investigating Mechanisms And Day-Level Factors That Influence Children’S 24-Hour Movement Behaviors, Hannah Parker

Theses and Dissertations

Twenty-four hour movement behaviors (i.e., physical activity (PA), screen time (ST), and sleep) are associated with health outcomes, chronic disease (obesity, type 2 diabetes), and mortality. Most literature evaluating children’s 24-hour movement behaviors has focused on static person-level demographic information such as age or biological sex. Relatively less work has examined the variable factors that change day to day, such as environment or context. The Structured Days Hypothesis (SDH) suggests that when children are in structured environments, they have healthier movement behaviors compared to less structured environments where children have more discretionary time to engage in obesogenic behaviors. Besides school/childcare, …

Causal Neuro-Symbolic Artificial Intelligence: Synergy Between Neuro-Symbolic And Causal Artificial Intelligence, Utkarshani Jaimini

Theses and Dissertations

Understanding and reasoning about cause and effect is innate to human cognition. In everyday life, humans continuously engage in causal reasoning and hypothetical retrospection to make decisions, plan actions, and interpret events. This cognitive ability allows us to ask questions such as: “What caused this situation?”, “What will happen if I take this action?”, or “What would have happened had I chosen differently?” This intuitive capacity to form mental models of the world, infer causal relationships, and reason about alternative scenarios, particularly counterfactuals, is central to our intelligence and adaptability. In contrast, current machine learning (ML) and artificial intelligence (AI) …

The Other Side Of Trusting: The Implications Of Vulnerability As A Core Component Of Organizational Relationships, Sam Dylan Strizver

Theses and Dissertations

Trusting behavior—discretionary risk-taking with another party—is the primary means of facilitating productive workplace relationships (Zand, 1979; Mayer, Davis, & Schoorman, 1995). Yet, little empirical evidence exists to explain what happens after employees engage in trusting behavior, but before outcomes materialize—otherwise termed the “vulnerability phase” (Ballinger, Schoorman, & Sharma, 2024: 2). To address this neglect, I develop a theoretical framework that positions vulnerability as a core psychological state within the trust process, shaped by trustors’ cognitive appraisals of risk severity and uncertainty. Drawing from research on stress and well-being, the framework also identifies coping as a key response to vulnerability, moderated …

Hearing The Unheard: Creating A Brave Space To Analyze The Experiences Of Men Of Color In Student Service Roles And Their Mental Health Challenges Within Higher Education, Calvin Maurice Joyner

Theses and Dissertations

This study analyzed the experiences of five men of color in student service roles dealing with mental health stressors, such as discrimination, workplace burnout, tokenism, and low morale. To highlight their experiences, a brave space was utilized as an intervention. The following questions were examined and answered within this qualitative, action research study: (1) What are the experiences of men of color with mental health challenges in student service roles? (2) How do mental health problems affect the personal and professional lives of men of color in student service roles? (3) How do the brave spaces impact the mental health …