Digital Commons Network^™

Reducing Seclusion In Inpatient Psychiatric Units Through Staff Education, Amaka Nkala

Walden Dissertations and Doctoral Studies

Seclusion remains a restrictive intervention used in inpatient psychiatric settings despite evidence linking it to psychological trauma, physical harm, and adverse patient outcomes. This Doctor of Nursing Practice (DNP) staff education project evaluated the effectiveness of a trauma-informed care and de-escalation education program in improving nurses' confidence in managing patient escalation. The project used a pre- and post-intervention quality improvement design with 24 inpatient psychiatric nurses. Participants completed a 10-item, 5-point Likert-scale confidence survey before and after a 30-minute educational session delivered via PowerPoint. Descriptive statistics were used to compare pre- and post-intervention confidence scores. Mean confidence scores increased from …

Staff Education Project To Teach Mobility And Sensory Aid Optimization Delirium Prevention Bundle For Older Patients In A Hospital Health System, Lerato Catherine Modise

Walden Dissertations and Doctoral Studies

Delirium is a preventable and manageable neuropsychiatric condition characterized by acute fluctuations in attention, awareness, and cognition. The burden of this acute confusion syndrome among older adults aged > 65 years is disproportionate higher, due to age-related neurocognitive vulnerabilities. Nurse-led delirium prevention interventions can reduce incidence from 70% to 20% following structured education, gaps persist in nursing knowledge around evidence-based prevention strategies. The purpose of this project was to evaluate whether a structured nursing education intervention on enhanced mobility and sensory aid optimization strategies, as components of the ABCDEF bundle, improved nursing knowledge compared to standard care practices. Nineteen registered nurses …

Lorascan: Detecting Backdoor Prompts In Low-Rank Adapters For Large Language Models Via Down-Projection Activation Spike, Doniyorkhon Obidov, Honggang Yu, Xiaolong Guo, Kaichen Yang

Michigan Tech Publications

Low-rank adaptation (LoRA) enables efficient specialization and distribution of large language models through compact adapters. However, untrusted adapters introduce a supply- chain threat: a backdoored adapter can cause a model to gen- erate harmful content, malicious code, political propaganda, or covert advertisements when an input contains a hidden trig- ger. Adapter-agnostic defenses merge the adapter with the base model, which dilutes backdoor signals and reduces detection performance. Existing adapter-aware methods do not address how to safely use a potentially backdoored adapter. Instead, they either train a defensive adapter to repair a backdoored base model, addressing the inverse problem rather than …

Genotypic Triggers: Exposing Pharmacogenomic Blind Spots Via Host-Specific Backdoors In Generative Antimicrobial Peptide Models, Doniyorkhon Obidov, Xiaolong Guo, Yonghui Li, Kaichen Yang

Michigan Tech Publications

Large Language Models (LLMs) have accelerated drug discovery, particularly in the automated design of antimicrobial peptides (AMPs). However, current validation pipelines for peptide generation models overlook historical precedents showing that certain drugs carry health risks predominantly for individuals with specific genetic profiles. In this paper, we demonstrate that such targeted health risks can be induced intentionally and at scale by manipulating models that generate peptide candidates. We introduce the Genotypic Trigger, a backdoor attack that shifts a model’s generative distribution toward peptides with elevated predicted immunogenicity risk, an adverse immune reaction, specifically for carriers of a tar- geted HLA allele, …

Givosiran Treatment Over 36 Months For People With Acute Hepatic Porphyria: A Plain Language Summary, Kristen Wheedena, Sue Burrell, Susana Monroy, Paolo Ventura, Marianne T. Sweetser, Gang Jia, Manish Thapar, Nicole Castellano

Department of Medical Oncology Faculty Papers

Plain Language Summary: What is this summary about? Acute hepatic porphyria, also called AHP, is a family of four rare genetic diseases: Acute intermittent porphyria (AIP) Variegate porphyria (VP) Hereditary coproporphyria (HCP) Delta-aminolevulinic acid dehydratase deficiency porphyria (ADP) These genetic diseases are caused when an enzyme that is involved in the production of a molecule called heme does not work normally. This leads to a buildup of the molecules that produce heme, which is toxic to the body. People with AHP have symptoms such as nausea (feeling sick), pain, tiredness, weakness in arms and legs, and vomiting, and these symptoms …

"Help Me Live It The Way You Do": Grounding Singaporean Responses To The Rorschach Situation, Casey Y. Lee

Electronic Theses and Dissertations

Contemporary research on the Rorschach and culture is striking for the latter’s disappearance as a variable of significance (Meyer et al., 2015; Meyer et al., 2007; Mihura et al., 2013; Viglione & Hilsenroth, 2001). This erasure is chronicled and reproduced in the narratives of universal objectivity, of extensive international meta-analyses, of replications, of standardized norms (Ritzler, 2004; Smith et al., 2018; Smith et al., 2020; Weiner, 2004). A different story emerges, however, when we ask, how has culture disappeared? The proposed study is a multimethod qualitative analysis of Singaporean responses to the Rorschach, aimed at generating sensitive yet critical discourses …

Development Of Minimalist Trifunctional Building Blocks For Chemical Biology Probe Synthesis, Luke E. Bohrer

Electronic Theses and Dissertations

The completion of the Human Genome Project in 2003 generated expectations that genomic information would accelerate the discovery of new protein drug targets and FDA-approved therapies. However, many small-molecule drug candidates continue to fail in clinical trials, and much of the human proteome remains undercharacterized in terms of structure, function, and disease relevance. Chemical tools are therefore essential for defining protein function, mapping protein interactions, and identifying disease-associated molecular mechanisms. Among these tools, small-molecule chemical probes provide a powerful strategy for connecting biological activity with target identification, functional analysis, and the development of effective therapies.

This dissertation describes the development …

Impact Of Taped Problems Intervention Modification On Children With Deafness, Clyniece Hodge

Electronic Theses and Dissertations

Children with hearing loss are at an increased risk of experiencing setbacks in various areas of life, including academic performance and employment opportunities. Academically, they are likely to experience poor academic achievement in reading, as well as in mathematics (ASHA, 2013). In comparison to gifted hearing students and average-ability hearing students, students with hearing loss are at a higher risk of low mathematics performance (Hassan & Mohammed, 2019). Despite these known challenges and risk factors, limited research has been conducted to identify effective intervention strategies for improving mathematical outcomes among this population. As such, this study aimed to evaluate the …

A Mixed-Methods Pilot Study Of A 10-Week Wellness Program For Resident Assistants, Emily L. Lee-Chong

Electronic Theses and Dissertations

This mixed-methods pilot study used semi-structured interviews with 15 resident assistants (RAs), complemented by descriptive pre- and post-test data from the Five Factor Wellness Inventory (FFWEL), to explore their lived experiences of participating in a 10-week wellness program grounded in the Indivisible Self Model of Wellness (IS-WEL). The purpose of this study was to examine the program's perceived influence on wellness practices and to explore the feasibility of implementing wellness-focused programming. Using a hermeneutic inquiry approach, the study identified four themes reflecting participants’ experiences throughout the program. Themes highlighted the importance of self-awareness through the IS-WEL model, the value of …

Development Of A Structurally Distinct Topbp1 Inhibitor That Enhances Parp Blockade And Reverses Osimertinib Resistance, Fang-Tsyr Lin, Shwu-Jiuan Lin, Kang Liu, Yang Xiao, Lidija A Wilhelms Garan, Helena Folly-Kossi, Weei-Chin Lin

Faculty, Staff and Students Publications

Therapeutic resistance remains a major challenge in cancer treatment, driven by compensatory signaling and stress response pathways that sustain tumor survival. Topoisomerase IIβ-binding protein 1 (TopBP1), a multifunctional scaffold protein with nine BRCT domains, integrates replication stress signaling with oncogenic networks and is frequently overexpressed in aggressive cancers. Its BRCT7/8 domains mediate critical interactions with E2F1, mutant p53, MIZ1, PLK1, and CIP2A, making TopBP1-BRCT7/8 an attractive therapeutic target. Using docking-guided screening and structure-activity relationship–driven optimization, we developed CS18 as a potent and selective BRCT7/8 inhibitor that disrupts oncogenic TopBP1 complexes without interfering with DNA replication. CS18 suppresses MYC transcriptional programs, …

Steptrigger: Contact-State-Triggered Backdoor Attacks On Vlm-Powered Legged Robots, Jiageng Zhang, Doniyorkhon Obidov, Kaichen Yang

Michigan Tech Publications

Large language models and vision-language models are increasingly used as high-level planners in robotic systems, using task goals and sensor summaries to select navigation or manipulation actions. This creates a new backdoor surface: a compromised planner can behave normally in most runs, yet change its target selection when a hidden trigger is present. Prior attacks on LLM-powered or embodied agents mainly rely on triggers that appear in language, camera-visible objects, scene semantics, or specific sequences of past actions. This paper presents StepTrigger, a contact-state-triggered backdoor attack for VLM-powered legged robots. The trigger is not a prompt token or a visible …

Wip: Developing A Generative Ai Autoethnography Assistant, Jyoti Suhag, Jennifer Drewyor, Kathryn Bugbee, Michelle Jarvie-Eggart, Lynn Albers, Leo Ureel

Michigan Tech Publications

Background: Generative AI (genAI) is transforming educational research, offering new possi-bilities for conducting interviews while local sandboxing minimizes data privacy risks and hallucinations. Purpose: This work-in-progress presents the AI Autoethnography Assistant, a project investigating how large language models (LLMs) can support autoethnographic interview design and execution. Approach: Using prompt engineering grounded in Interpretative Phenomenological Anal-ysis, paraphrasing techniques, and structured follow-up questions, we developed protocols that incorporate po-sitionality and prompt reflection on origin stories and pivotal life moments. Outcomes: Conversations conclude at the user’s discretion, with the AI generating a thematic summary. We tested refined prompts across four platforms (Gemini, Claude, …

Fragberta: A Fragment-Aware Molecular Representation Model With Sequential Attachment-Based Fragment Embeddings, Neerav Kaushal, Ajay M.N.V. Penmatsa

Michigan Tech Publications

Automated exploration of chemical space through machine learning has become a central strategy in modern drug discovery, where the ability to learn transferable molecular representations directly impacts predictive modeling performance. Recent advances in chemical language models have primarily relied on atom-level string encodings such as SMILES or SELFIES, treating molecules as sequences of individual atoms or characters. However, medicinal chemistry reasoning is often fragment-centric, emphasizing scaffolds, functional groups, and modular substructures rather than isolated atoms. In this study, we introduce FragBERTa, a molecular fragment-aware transformer-based representation language model pretrained using masked language modeling on Sequential Attachment-based Fragment Embedding (SAFE) representations. …

Improving Bench Work Competence Through Qr Code Based E-Lkpd Featuring Sop Video And K3 Safety Checklist, Firman Muhadi Saputra, Marsono Marsono, Imam Muhtarom, Mingchang Wu

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study examines the use of a QR Code-based E-LKPD integrated with SOP videos and a K3 safety checklist in improving vocational students’ bench work competence. A pretest–posttest control group design was applied to 63 tenth-grade machining students at SMKN 1 Jenangan Ponorogo in the 2025/2026 academic year selected through purposive sampling. Data were collected using performance assessment observation sheets and written tests. The results show that both groups achieved the competent category, with the experimental class obtaining a slightly higher mean score (80.22) than the control class (77.07), However the independent t-test results indicate that the difference is not …

Heuristic Inquiry As A Research Method In Music Education, Austina F. Lee

Visions of Research in Music Education

This article presents heuristic inquiry as a form of autoethnography and its potential as a methodological resource for music educators. Rather than reporting findings from a single study, the article illustrates how heuristic inquiry can serve as a structured yet flexible process of critical reflection that helps teachers navigate the cultural and political contexts of their work. Drawing on the author’s experiences as a high school choral director, the discussion highlights the six phases and seven processes of heuristic inquiry, showing how personal reflection, cultural awareness, and relational care can be interwoven into professional practice. By framing autoethnography as both …

Consequences Of Teacher Violence Among Musicians, Karla María Reynoso Vargas, Basilio Fernández-Morante

Visions of Research in Music Education

This is a standalone work, but it is complementary to the study, “Teacher violence in university music education: An exploration in a Mexican context.” It presents the analysis of emerging information found in 53 stories of victims of teacher violence in university music programs. We incorporated reflections and contributions from students, professionals, and dropouts of music careers in the Mexican Republic, who voluntarily shared their stories. The first category describes the consequences of teacher violence. On one hand, there were effects interpreted as positive, including the activation of achievement orientation, overexertion, and self-demand. It is pointed out that these consequences …

Teacher Violence In University Music Education: An Exploration In The Mexican Context, Karla María Reynoso Vargas, Basilio Fernández-Morante

Visions of Research in Music Education

This article presents the results of an exploratory phenomenological study aimed at identifying expressions of teacher violence in university music training environments in the Mexican context. We analyzed 53 accounts from students, professionals, and dropouts of music degree programs who studied at universities or conservatories across nine Mexican states and voluntarily shared their testimonies through the Mexican Association of Music Psychology (AMEPSIM). We address sociological assumptions about the dynamics of violence, the socio-educational weight of the conservatory tradition and its potential link to the limited application of contemporary pedagogical principles, as well as the normalization of teacher violence. Various forms …

A Sociological Framework For Spatial Analyses Of Institutional Musicking In Conflict Spaces, Carol Frierson-Campbell

Visions of Research in Music Education

This essay presents a framework that brings spatial sociology together with Small’s (1998, 1999) concept of musicking and Born’s (2011, 2012, 2015) Planes of Music Sociality. It was developed as an analytical scheme for an ongoing case study of musicking via the Edward Said National Conservatory of Music (ESNCM), the national music conservatory of Palestine. Small’s notion of musicking reminds music educators that musicking activities communicate meanings beyond the obvious: Individual and collective ideals about relationships with sound, with other people, and with the spaces they inhabit. Born’s conception of musical socialities as four interacting planes goes beyond Small’s ideas …

Teacher Education In The Arts: A Case Study Of Constraint, Standardization, And Resistance, Terry Sefton, Danielle Sirek

Visions of Research in Music Education

In this case study, we explore one course in one Ontario initial teacher education program to examine the intersecting institutional documents and practices that regulate teaching in the arts (dance, drama, music, and visual arts). Using the feminist sociological research approach of institutional ethnography, we identify and trace institutional mechanisms that regulate teaching in the arts and how four women instructors activated or resisted those regulatory practices. Our analysis illuminated tensions between institutional policies and practices, and instructors’ efforts to maintain creativity, ambiguity, and discipline-specific experiential learning in the course. While instructors varied in their pedagogical approaches, over a seven-year …

Editorial: Colaboraciones A Través De Las Culturas/Collaborations Across Cultures, Cara Faith Bernard, Jennifer Lang

Visions of Research in Music Education

No abstract provided.

Technical Reliability As Foundation Of Mobile Self-Checkout Experience, Pumezile O. Dyantyi, Fazlyn Petersen

African Conference on Information Systems and Technology

Although mobile self-checkout (MSCO) apps are becoming more common in retail stores, their long-term success in emerging markets depends heavily on the system’s technical reliability. This qualitative thematic study of 888 user reviews for four established MSCO apps investigates how technical reliability shapes the user experience (UX) after app adoption. Using an integration of the UX Honeycomb model and the UTAUT2 framework, this paper demonstrates that technical reliability is a core UX element that affects usability, performance, trust, value, satisfaction and continued use. Technical reliability problems such as system outages, login challenges and transaction difficulties negatively impact several core UX …

Factors Hindering E-Procurement Adoption In South African State-Owned Enterprises: A Scoping Review, Lumka T. P. Salamntu, Zintle Ntlokwana

African Conference on Information Systems and Technology

e-Procurement is a digital management system that oversees the entire purchasing process, encompassing acquisition, procurement, and payment. e-Procurement aims to enhance efficiency, minimise redundancies and reduce paper-based processes. In South Africa, State-Owned Enterprises (SOEs) view e-Procurement as a strategic tool used to optimise processes, improve efficiency, accountability and transparency. This study followed a scoping review protocol and analysed eighteen articles which were written in the English language. The Rayyan screening software was used to screen and manage articles during the selection process. A search strategy was developed, and the search was conducted across four electronic databases from 2020 to 2025 …

Digital Learning Platforms And Academic Performance In Ghana, Gifty S. Hlovor

African Conference on Information Systems and Technology

Digital learning platforms are increasingly integrated into secondary education across Africa. In Ghana, the Ministry of Education (MoE) introduced the Curriculum Microsite as a digital repository to support the new Senior High School (SHS) curriculum. Despite its broad deployment, empirical evidence on how students engage with the platform and whether such engagement translates into improved academic performance remains limited. Grounded in Task-Technology Fit (TTF) theory, this work-in-progress presents a quantitative, cross-sectional survey study examining the behavioral patterns and modes of use of digital learning platforms among SHS students in Ghana and their association with academic performance. This study contributes to …

From Crisis Necessity To Sustained Use: A Process Model Of Mobile Banking Use In An Unequal Global South Context, Saadiek Basadien, Molefe Maloma, Mariam Jacobs-Basadien, Papama Mtambeka

African Conference on Information Systems and Technology

Mobile banking (m-banking) has become an important financial infrastructure, especially during crises. This study examines how users in the Western Cape, South Africa, adopted m-banking during the COVID-19 pandemic. Using a qualitative design with a construct-informed interview guide and thematic analysis of interviews, we show that adoption was driven less by innovation-seeking and more by situational necessity to maintain financial continuity and minimise health risk. Over time, crisis-triggered use evolved into value-sustained engagement anchored in convenience, financial control, and growing digital confidence. The findings identify social mediation, risk-management practices, and digital literacy as key mechanisms shaping this trajectory. We developed …

Enzymatic Synthesis Of Salicylate In Yersina Pestis Proceeds Via Intramolecular Hydroxyl Group Transfer., Clarke Miller

Georgia Journal of Science

The salicylate synthase (YbtS) of Yersinia pestis catalyzes the initial step in the biosynthesis of yersiniabactin, an iron-scavenging siderophore and critical virulence factor. While YbtS is proposed to share a  reaction mechanism with other anthranilate synthase homologs, the exact catalytic pathway has remained unresolved.  In this work, stable isotope (¹⁸O) labeling and mass spectrometry are utilized to clarify the catalytic mechanism of YbtS.  The results of the following set of experiments demonstrate that the salicylate hydroxyl group does not originate from solvent water, directly challenging previously proposed models. Instead, the lack of solvent-labeled oxygen incorporation and the absence …

Caging Songwriters In The Compulsory Licensing Framework: A Battle Of Fairness And Equity, Maria Kaganis

St. John's Law Review

(Excerpt)

Imagine it is November 2023, and you log onto Spotify to stream your favorite music. As you do, you notice you now have access to up to fifteen hours of the most popular audiobooks. You really enjoy the addition of audiobooks to Spotify and have used the new feature for months. Come March of 2024, however, you get an email stating that Spotify will be introducing a . . . music-audiobook bundle as part of your current subscription? Is that not what you already had? Shrugging it off, you move on and continue enjoying your music, audiobooks, and podcasts …

South Africa's Inclusive Six-Dimensional Generative Ai Readiness Framework, Keegan Steyn, Ojelanki Ngwenyama, Sibongiseni Tunzelana

African Conference on Information Systems and Technology

Generative artificial intelligence (Gen AI) is transforming governance, knowledge systems, and economic activity, but current preparedness measures pay little attention to the socio-technical, institutional, and postcolonial contexts that shape country trajectories. To address this gap, the study employs a design science methodology to create the National Generative AI Readiness Assessment Framework (N-GAIRF), a six-dimensional diagnostic tool theoretically based on Sen's capability approach to development and incorporating Institutional Theory, Socio-Technical Systems Theory, National Innovation Systems Theory, and Postcolonial Information Systems critique. An example application to South Africa, compared to Zimbabwe and an indicative Organization for Economic Cooperation and Development (OECD) reference …

Utilization Of An Open-Access Markerless Motion Analysis Software For A Biomechanics Movement Analysis Project., Tamra L. Llewellyn, Michael J. Nolan

Educational Practices in Kinesiology

The movement analysis project (MAP) is a common assignment in many undergraduate biomechanics courses. The purpose of this article is to introduce kinesiology educators to an open-source, AI-enabled, markerless software for motion capture, OpenCap, which can be used in MAP and research. This tool is currently being used in an in-person, upper-level, undergraduate biomechanics course where students are required to have taken Anatomy & Physiology. There is very little time, money, or expertise needed to implement this resource. Using 2 iPads on tripods and the OpenCap app and web-based interface, movements can be quickly converted to skeleton visualization and joint …

Social Media Motivations And Crisis Engagement Among Generation Z: A Uses And Gratification Perspective, Edina Galaa, Sulemana Bankuoru Egala, John Asibuo Boakye, Abdul-Hamid Sokun Alhassan

African Conference on Information Systems and Technology

Generation Z's growing use of social media during crises raises important questions about their motivations. This study applies Uses and Gratification Theory to investigate how four motivations — entertainment, social recognition, information sharing and altruism- drive Gen Z’s media use during emergencies and whether empathy moderates these effects. Using a scenario-based survey of 319 respondents and Partial Least Squares Structural Equation Modelling analysis, findings reveal that social recognition and altruism motivation significantly influence social media use intensity, while entertainment seeking and information sharing intention do not. Importantly, social media use intensity simultaneously predicts both prosocial need fulfilment and content validation …

Gci Hydrocarbon Normalization & Mechanical Fuel Conditioning Platform (V1.5), Michael Victor Caldwell Mr.

Defensive Publications Series

GCI Hydrocarbon Normalization & Mechanical Fuel Conditioning Platform (v1.5)

This technical architecture outlines the builder-ready integration and test-bench realization of the GCI Hydrocarbon Normalization & Mechanical Fuel Conditioning Platform (v1.5). By unifying multi-system innovations across the Caldwell open-hardware portfolio—specifically integrating biomimetic fishbone micro-channel flow conditioning from the Mechanic’s Battery (GCI #288-ULTRA), Helmholtz acoustic resonance and microbubble cavitation arrays from CVNR-F1.5, high-velocity convergent-divergent shear mechanics from VETI-3.0, anisotropic CTE-tuned thermal control from the Arachne v8.7 substrate, and gyroid-lattice thermal buffering from Forgecell Prime—this platform provides a completely mechanical, non-catalytic method for processing complex hydrocarbon streams.

The system achieves continuous molecular chain …