Digital Commons Network^™

Acute Loss Of Tactile Input Leads To General Compensatory Changes In Eye-Hand Coordination During Object Manipulation, Kevin Ung, John F Magnotti, Brandon Kim, Jeffrey M Yau, Per F Nordmark

Faculty, Staff and Students Publications

Current models of motor control emphasize the critical role of sensory feedback, as demonstrated by movement coordination deficits following sensory impairment. When both vision and touch are available for object-oriented manual behaviors, they serve distinct roles; vision guides the execution of planned movements, while touch provides more direct feedback on hand-object interactions. The impact of losing somatosensory feedback on eye-hand coordination during dexterous object manipulation tasks has not been thoroughly studied. Conceivably, vision is recruited to compensate for the feedback lost when touch is abolished based on the dexterity demands of the behavior. To investigate this, we tested healthy participants …

High-Resolution Peripheral Quantitative Computed Tomography Reliability And Accuracy Of Bone Density And Morphology Properties In Children, Roman J Shypailo, Chadi Calarge, Punam K Saha, Xiaoliu Zhang, Xiaojie Chen, Stephanie Dinh, Xiaofan Huang, Babette S Zemel, Fida Bacha

Faculty, Staff and Students Publications

Volumetric bone density, microarchitecture, and strength measures using HR-pQCT are valuable measures of bone health in pediatrics. Our cross-sectional study evaluated bone measure reproducibility in pediatric participants using repeat HR-pQCT (XtremeCT II, Scanco Medical) scans of non-dominant distal tibia and radius of 30 healthy children and adolescents (7-17 yr, 47% female) by 2 technicians. Additionally, we examined HR-pQCT and micro-CT of 26 cadaveric distal tibia specimens to evaluate agreement between the modalities. All HR-pQCT scans were analyzed using manufacturer-provided software (Image Processing Language, Scanco Medical) and a fully automated, previously validated, in-house algorithm, offering measures of bone microstructure (eg, trabecular …

Treatment Of Cutaneous Collagenous Vasculopathy With Pulsed Dye Laser, Hannah L Hanania, Isabella Camacho-Hubbard, Zeena Y Nawas

Faculty, Staff and Students Publications

Objectives: Cutaneous collagenous vasculopathy (CCV) is a rare, idiopathic microangiopathy marked by widespread telangiectasias and histologic vessel wall thickening. Due to its rarity and clinical overlap with other vascular conditions, CCV poses diagnostic and therapeutic challenges. This report highlights the successful use of pulsed dye laser (PDL) therapy in treating a case of extensive CCV.

Methods: A 40-year-old woman with a decade-long history of progressive telangiectasias involving the extremities, trunk, and forearms underwent treatment with a 595-nm PDL. Six treatment sessions were conducted over 14 months.

Results: The patient experienced significant improvement in erythema, telangiectasias, and associated discomfort, with sustained …

Strong External Difference Families And Classification Of Α-Valuations, Donald L. Kreher, Maura B. Paterson, Douglas R. Stinson

Michigan Tech Publications

One method of constructing (Formula presented.) -SEDFs (i.e., strong external difference families) in (Formula presented.) makes use of (Formula presented.) -valuations of complete bipartite graphs (Formula presented.). We explore this approach and we provide a classification theorem which shows that all such (Formula presented.) -valuations can be constructed recursively via a sequence of “blow-up” operations. We also enumerate all (Formula presented.) -SEDFs in (Formula presented.) for (Formula presented.) and we show that all these SEDFs are equivalent to (Formula presented.) -valuations via affine transformations. Whether this holds for all (Formula presented.) as well is an interesting open problem. We also …

The Cosmoverse White Paper: Addressing Observational Tensions In Cosmology With Systematics And Fundamental Physics, Eleonora Di Valentino, Jackson Levi Said, Adam Riess, Agnieszka Pollo, Vivian Poulin, Adrià Gómez-Valent, Elena Giusarma, Et Al.

Michigan Tech Publications

The standard model of cosmology has provided a good phenomenological description of a wide range of observations both at astrophysical and cosmological scales for several decades. This concordance model is constructed by a universal cosmological constant and supported by a matter sector described by the standard model of particle physics and a cold dark matter contribution, as well as very early-time inflationary physics, and underpinned by gravitation through general relativity. There have always been open questions about the soundness of the foundations of the standard model. However, recent years have shown that there may also be questions from the observational …

Wood-Water Relationship And Micro-Chemical Properties Of Huminated Archaeological European Elm (Ulmus Laevis P.), Amir Ghavidel, Shennan Wang, Miklós Bak, Lauri Rautkari, Reza Hosseinpourpia

Michigan Tech Publications

Archaeological wood requires effective conservation to prevent further degradation, and traditional modifications such as polyethylene glycol (PEG) have limitations, including hygroscopicity and chemical degradation over time. To explore alternative modification, this study was conducted to investigate the suitability of humins, crosslinked with different concentrations of succinic acid (SA), to protect archaeological elm wood from the Agapia Monastery against water and to determine the modification mechanism. Key parameters such as dimensional stability, moisture sorption isotherms, and determination of accessible hydroxy groups as a function of humination modification were analyzed using dynamic vapor sorption (DVS). The modification mechanism was studied by microstructural …

Exploring Boundaries With Food, Substances, And People In Substance Use Recovery: A Qualitative Analysis, Tiffany Champagne-Langabeer, Audrey Sarah Cohen, Kriti Shrestha, Jie Zhu, Audrey Lopez, Alisha Campbell, Christine Bakos-Block

Faculty, Staff and Student Publications

Background: In the United States, over 47 million youth and adults live with a substance use disorder (SUD). These individuals are frequently malnourished and have metabolic dysregulation as a result. Nutrition interventions incorporating a mindfulness-based approach help recovery efforts that are physical and mental.

Objective: The objective of this study was to explore and analyze the perspectives and experiences of individuals with SUD regarding emotional regulation and nutrition. The study used a mixed methods approach to generate insights for improving recovery support and developing future interventions.

Design: In 2024, an exploratory mixed methods study was conducted based on a large …

Incorporation Of E-Waste Plastics Into Asphalt: A Review Of The Materials, Methods, And Impacts, Sepehr Mohammadi, Dongzhao Jin, Zhongda Liu, Zhanping You

Michigan Tech Publications

This paper presents a comprehensive review of the environmentally friendly management and reutilization of electronic waste (e-waste) plastics in flexible pavement construction. The discussion begins with an overview of e-waste management challenges and outlines key recycling approaches for converting plastic waste into asphalt-compatible materials. This review then discusses the types of e-waste plastics used for asphalt modification, their incorporation methods, and compatibility challenges. Physical and chemical treatment techniques, including the use of free radical initiators, are then explored for improving dispersion and performance. Additionally, in situations where advanced pretreatment methods are not applicable due to cost, safety, or technical constraints, …

Comprehensive Review Of In Vitro Approaches For Environmental Heavy Metal Exposure, Manas Warke, Madeline English, Camila Padilla, Lexie Gasco, Wendy Leisner, Rupali Datta, Smitha Rao

Michigan Tech Publications

Heavy metals are ubiquitous environmental pollutants, contaminating air, soil, and water via the erosion of natural deposits, as well as originating from anthropogenic sources, such as agriculture, industries, transportation, and landfills. The increasing utilization of heavy metals over the years, combined with the persistent nature of metals in the environment poses a direct threat to human and environment health. Although regulatory limits have been established for toxic metals, assessing the associated health risks using real-life exposure scenarios remains challenging. In this review, we summarize the development and use of in vitro models based two- and three-dimensional cell culture systems, focusing …

Experiences And Perspectives Of Sexual And Reproductive Health Among Women In Recovery From Opioid Use Disorder, Nicole M. Mattson, Aleigha Barry, Jessica L. Zemlak

College of Nursing Faculty Research and Publications

Background

Women in recovery from opioid use disorder (OUD) have unmet sexual and reproductive health (SRH) needs resulting in health disparities such as unintended pregnancy and sexually transmitted infections/HIV infection compared with women without OUD. The purpose of this qualitative descriptive study was to explore the perceptions and experiences of co-occurring multiple social-ecologic influences (individual, interpersonal, community, society) on SRH among women in recovery from OUD.

Methods

Purposive sampling was used to recruit cis-gender women aged 18–49 who self-identify as being in recovery from OUD and speak English. We conducted one 45- to 60-minute audio-recorded semistructured telephone interview with each …

The Importance Of A Transport Medicine Rotation For A Pediatric Critical Care Fellowship, Jennifer K. Pfister, Katie L. Mcdermott, Christine A. Schindler, Tara L. Petersen, Ke Yan, Melodee A. Liegl, Prakadeshwari Rajapreyar

College of Nursing Faculty Research and Publications

Background

Pediatric critical care medicine (PCCM) fellowship programs must meet established educational standards; however, interfacility transport opportunities vary across sites.

Objective

To query key stakeholders, is the interfacility transport medicine rotation still an important component of the PCCM fellowship?

Methods

A multi-methods questionnaire was sent to a convenience sample (n = 66) of key stakeholders, including attending physicians, PCCM fellows, and transport team members, from a single site. An 80% response rate resulted in a total of 53 participants. Quantitative items used a Likert-scale and forced ranking response options. Qualitative responses were obtained regarding challenges and barriers during the …

Botulinum Neurotoxin Light Chain/A1 Uses Fast Synaptic Vesicle Cycling To Cleave Plasma Membrane Bound Snap-25, Alexander Gardner, Molly Sneller, William H. Tepp, Joseph T. Barbieri, Sabine Pellett

College of Nursing Faculty Research and Publications

Botulinum neurotoxins (BoNT) are the most potent protein toxins for humans, yet how BoNT-Light Chain/A1 (LC/A1) journeys to cleave intracellular SNAP-25 is understudied. Here we use a cell-based assay to measure cytosolic EGFP-LC/A1 intracellular trafficking and SNAP-25 cleavage in Neuro-2A cells. Intracellular LC/A1 associated on microtubules and co-localized with Rab GTPases involved in fast synaptic vesicles and endosome recycling. Multiple Dominant Negative (DN) Rabs GTPases involved in fast synaptic vesicles or endosome recycling inhibited LC/A1 trafficking to the intracellular plasma membrane and SNAP-25 cleavage. A cytosolic LC/A1 variant that bound the plasma membrane from the cytosol was insensitive to DNRab …

Moderate Coffee And Tea Consumption Is Associated With Slower Cognitive Decline, Stephanie R. Rainey-Smith, Kelsey R. Sewell, Belinda M. Brown, Hamid R. Sohrabi, Ralph N. Martins, Samantha L. Gardener

Research outputs 2022 to 2026

Background: Globally, coffee and tea are consumed extensively, potentially providing neuroprotection through anti-inflammatory and antioxidative stress effects. Objective: This study aimed to investigate associations between coffee and tea intake and cognitive function. Methods: In a longitudinal prospective cohort study, dementia-free (n = 8715; age range 60.0–85.2 years) older adults from the UK Biobank self-reported coffee and tea intake over the previous year; ‘never’, ‘moderate’ (1–3 cups/day), or ‘high’ (≥4 cups/day). Participants completed cognitive assessments at ≥2 timepoints (mean of 9.11 years). Results: Those ‘never’ consuming coffee and ‘moderate’ coffee consumers (β = 0.06, p = 0.005; β = 0.07, p <  0.001, respectively), as well as ‘moderate’ tea consumers and ‘high’ tea consumers (β = 0.06, p = 0.009; β = 0.06, p = 0.003, respectively) had slower fluid intelligence decline. Additionally, those ‘never’ consuming coffee and ‘moderate’ coffee consumers had a slower increase in pairs matching errors (β = −0.05, p = 0.022; β = 0.05, p = 0.013) compared to ‘high’ consumers. Conclusions: ‘Moderate’ coffee, and ‘moderate’ and ‘high’ tea intake may be a protective factor against cognitive decline. Randomized controlled trials are required to establish causal relationships leading to evidence-based recommendations regarding benefits of coffee and tea intake.

Prevalence Of Oral Mucosal Lesions Among Geriatric Dental Patients In Egypt: A Cross-Sectional Study, Dalia Ghalwash, Ahmed Hamdy, Sara Abd El-Wahed

Dentistry

Background. The oral health needs of older adults must be prioritized due to the shifting demographics of the population and rising life expectancy. This study investigated the prevalence of oral mucosal lesions (OMLs) among geriatric dental patients in a sample of the Egyptian population and explored the association with age, gender, smoking habit, as well as the impact on the quality of life. Methods. This cross-sectional study screened 300 geriatric dental patients aged 65 years or older, from several dental hospitals and mobile clinics in various regions in Egypt. Demographic data and information regarding denture use, systemic diseases, and smoking …

Lipid And Cholesterol Peroxidation Leads To Α-Crystallin Membrane Aggregation And Cataract Formation, Nawal K. Khadka, Preston Hazen, Oluwaseyi Akinola, Xinzhu Pu, Laxman Mainali

Boise State University Publications and Presentations

Purpose: The significant lens chaperone protein α-crystallin (αABc), comprised of αA-crystallin (αAc) and αB-crystallin (αBc) subunits, is found to form membrane-bound aggregates with age and cataract formation. However, the molecular basis for such aggregate formation is still unclear. Our research primarily aims to elucidate the effect of lipids (phospholipids and sphingolipids) and cholesterol (Chol) peroxidation on the aggregation of αAc, αBc, and αABc to bovine lens nuclear membrane (NM).

Methods: Lipid and Chol peroxidation was induced by a photosensitized peroxidation reaction, and topographical images of NM and oxidized-NM (Ox-NM) with and without αAc, αBc, or αABc were obtained using atomic …

Some Remarks On Invertible Refined Neutrosophic Square Matrices, Ahmad A. Abubaker, Abdallah Shihadeh, Mayada Abualhomos, Khaled Matarneh, Mutaz Mutaz Shatnawi, Ahmed Atallah Alsaraireh, P. Prabakaran, Abdallah Al-Husban

Neutrosophic Sets and Systems

No abstract provided.

A Novel Neutrosophic Multi-Layered Complex Refined Hyperstructure: Theoretical Advancement With Illustrative Examples From Employee Mental Health Education Effectiveness In Enterprises, Min Zhang, Yaozu Wang, Rui Huang, Qiao Wu, Bingqing Bingqing Li

Neutrosophic Sets and Systems

No abstract provided.

Enhancing Decision-Making In Piezoelectric Energy Harvesting Systems Through Neutrosophic Logic, A. A. Salam, Mohamed A. Mohamed, Hanan M. Amer, Musallam Jeailan Hzam Alzubi, Huda E. Khalid, Ahmed K. Essa

Neutrosophic Sets and Systems

No abstract provided.

A Multi-Criteria Decision-Making Framework For Evaluating Emerging Digital Technologies In Supply Chain Optimization, Nabil M. Abdelaziz, Dina Mohamed, Hasnaa Soliman

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Probabilistic And Statistical Extensions Of The Neutromultispace Model For Blended Teaching Process In University Physical Education: A Novel Neutrosophic Modeling Framework, Guoquan Lin, Hongtao Guo, Ying Zheng

Neutrosophic Sets and Systems

No abstract provided.

A Linear Mathematical Model Of The Vocational Training Problem In A Company Using Neutrosophic Logic, Hyperfunctions, And Superhyperfunction, Maissam Jdid, Florentin Smarandache, Takaaki Fujita

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Logic For Secure Hand-Based Biometrics: Quantifying Privacy-Security Tradeoffs In Remote Authentication Systems, A. A. Salama, Abdelnasser Mohamed, Huda E. Khalid, Ahmed Essa, Doaa E. Mossa

Neutrosophic Sets and Systems

No abstract provided.

Neutrosophic Components Structure Semigroups For Risk Evaluation Of Financial Archive Management In Small And Medium-Sized Enterprises, Zhongyin Dong, Pei Wan

Neutrosophic Sets and Systems

No abstract provided.

A Neutrosophic Reversibility Tensor Model For Analyzing Quality Dynamics In Academic Discipline Construction At Local Application-Oriented Universities Based On Artificial Intelligence Technology, Chang Liu

Neutrosophic Sets and Systems

No abstract provided.

A Superhyperuncertain Information Systems Model For Sustainable Tourism Competitiveness In Rural Forest Parks, Yanyan Zhang, Ting Zhou

Neutrosophic Sets and Systems

No abstract provided.

Linguistic Pythagorean Hypersoft Set With Application: Decision Making In Medical Diagnosis And Treatment, Sathiyapriya Bangarusamy, Dr. V.Pankajam

Neutrosophic Sets and Systems

No abstract provided.

Application Of Neutrosophic Micro Binary Topological Space, C. Sangeetha, G. Sindhu, S.S. Surekha, Smitha G

Neutrosophic Sets and Systems

No abstract provided.

A Novel Neutrograph Model For Dynamic Systems: Advancing Neutrostructures With Partially False Axioms In Interactive Digital Installation Art Design, Ziyuan Liu, Yixi Peng

Neutrosophic Sets and Systems

No abstract provided.

Single Valued Neutrosophic Twofold Algebra For Measuring Education Quality Standards In The Academic Administration Of University Mathematics Programs, Yong Zhou, Zengbo Wang

Neutrosophic Sets and Systems

No abstract provided.

A Nonstandard Neutrosophic Model For Aesthetic Response In Interactive Device Decorative Art Design, Xing Wei

Neutrosophic Sets and Systems

No abstract provided.