Digital Commons Network^™

Development Of Urchin-Like Gold Nanoparticles For Drug Delivery Of The Glioblastoma And The Colorectal Cancer Cells, Joshua Ozougwu, Vinayak Shama, Bilal Javed Dr., Furong Tian Dr.

Journal of Academic Research and Innovation

Urchin-like gold nanoparticles have shown to enhance cytotoxicity against cancer cells compared to original gold nanoparticles making them a ‘promise’ for cancer treatment because of their specific size inducing more hot spots and produced surface/volume ratio. Different concentrations of urchin-like gold nanoparticles can be synthesised to observe the different effects the particles pose against the cancer cells. Urchin-like AuNPs were synthesised using the chemical reduction method to synthesise gold nano seeds. Hydroquinone was used to create the urchin shape of the gold nanoparticles. In vitro, cytotoxicity studies were performed to observe which concentration of urchin-like AuNPs had a stronger cytotoxicity …

Analysis Of Gold Nanoparticles To Develop The Rapid Antigen Biosensing Strips For The Detection Of Toxins, Trang Nguyen Minh Long, Perveen Akhtar, Gayathree Thenuwara, Vinayak Sharma, Furong Tian, Bilal Javed

Journal of Academic Research and Innovation

Zearalenone (ZEN), a mycotoxin produced by Fusarium fungi, is a significant food safety concern due to its widespread contamination in cereal crops and its estrogenic effects on both human and animal health. Although traditional analytical methods such as HPLC and ELISA are very sensitive but they are laborious, expensive, and unsuitable for on-site screening. This paper focused on developing a rapid, cost-effective, and fast lateral flow immunoassay (LFIA) for ZEN detection, using gold nanoparticles (AuNPs) as label particles that were immobilized with anti-ZEN antibodies. AuNPs were synthesized using the Turkevich–Frens method, showing a UV–Vis absorption peak at 520 nm and …

The Golden Standard: Potential Of Gold Nanoparticles In Cancer Research And Therapy, Caoimhe Mcmanus, Shubhrima Ghosh Dr.

Journal of Academic Research and Innovation

Conventional cancer treatments, such as chemotherapy and radiation therapy, have been fundamental in the treatment of cancer. However, these therapies are often limited due to serious side effects, including non-specific targeting of healthy tissues, systemic toxicity, and resistance to treatment. These limitations are currently being addressed by emerging therapies that can provide more effective and precise therapeutic approaches, such as immunotherapy and nanomedicine. Gold nanoparticles (AuNPs) have shown great promise in cancer research and treatment due to their distinct physicochemical characteristics, biocompatibility, and versatility. This literature review aims to discuss conventional cancer therapies and further explores the potential of nanoparticles …

Special Issue, Nanolab Research Centre Students Articles, Preface And Contents, Furong Tian

Journal of Academic Research and Innovation

No abstract provided.

Synthesis Of Nitrogen-Enriched 3d Graphene Foam For Electrochemical Sensing Of Hydrogen Peroxide (H₂O₂), Bhargavi Dronavalli, Madhava Rao Vallabhaneni, Jatla Murali Prakash, Deepti Kolli, Dandamudi Srilaxmi

Karbala International Journal of Modern Science

In this work, A simple hydrothermal process was utilized to create 3D-foam-type Nitrogen-doped graphene (NDG). The synthesized material was characterized using a range of physicochemical characterization techniques. These techniques confirm that nitrogen is successfully incorporated into the carbon network, resulting in NDG. Cyclic voltammetry (CV) investigation demonstrated that NDG-modified glassy carbon electrode (NDG/GCE) displayed finite charge transfer properties against typical redox systems. NDG/GCE is identified as a simple, facile, and efficient electrocatalyst material for the estimation of hydrogen peroxide (H₂O₂). From CV analysis, it is revealed that NDG/GCE can produce a signal for electrochemical quantification of …

Comparing The Pull Out Resistance Of Two Typs Of Posts Used In Restoration Of Severely Damaged Primary Anterior Teeth )A Comparative In Vitro Study.(, Ayham H. Hijaz, Mohamed Kamel Altinawi2 K. Altinawi

Arabian Journal of Pediatric Dentistry

Background: severely damaged primary anterior teeth that require pulp therapy present a high-risk of failure due to the loss of tooth substance resulting from pre-existing decay and endodontic therapy itself. The ideal post material should have physical and mechanical properties that are similar to those of dentin . Another concern in restoring endodontically treated primary teeth is the need to find a material that can resorb in a similar way to natural tooth structure as a part of the exfoliation process allowing normal eruption of permanent successors . Accordingly there is no such material other than dentine itself.The introduction of …

Evaluation Of Dentinal Bridge Formation And Canal Obliteration After Pulpotomy In Primary Molars Using Mta And Bioceramic Putty (Well-Root-Pt), Ibrahim S. Alnassar, Mohamed K. Altinawi, Mohammad S. Rekab

Arabian Journal of Pediatric Dentistry

Summary: Preserving the primary teeth is important, as it plays an important role in the integrity of the dental arch, the development of the craniofacial complex, and the integrity of speech and chewing, as early loss of primary teeth leads to cosmetic, functional and verbal problems.

Objective: This study aimed to evaluate the formation of the dentinal bridge and canal obliteration after pulpotomy n in the primary molars using both mineral trioxides aggregate and Bioceramic putty (Well_Root PT) in the pulpotomy of the primary molars.

Materials and Methods: The study sample included forty second lower primary molars …

Evaluation Of The Time Taken To Remove Caries From Immature Permanent Molars Using Brix 3000 Gel Compared To The Traditional Rotary Method (Clinical Study), Malek Rajab, Samar Alsalameh, Shadi Azzawi

Arabian Journal of Pediatric Dentistry

Background: The traditional method of removing caries using rotary instruments is associated with a number of disadvantages, such as thermal effects that are harmful to the pulp tissue and excessive preparation of the dental tissue, in addition to the feeling of discomfort, fear, and anxiety that accompany it.

Aim: This study aims to evaluate the time taken to remove caries by the chemo-mechanical method using Brix 3000 compared to the traditional rotary method.

Materials and methods: The study sample consisted of 30 permanent first molars with Class I dentine caries, in 30 children between 7 and 9 years …

The Relationship Between Body Mass Index And Oral Health Indices In Adolescent Children: A Cross-Sectional Study., Lana Anwar Alshayeb, Mayssoon A. Dashash

Arabian Journal of Pediatric Dentistry

Background and Objective: The prevalence of obesity has increased dramatically worldwide in recent years, becoming a growing public health concern globally, especially among children, due to its association with systemic health. Despite emerging evidence suggesting a bidirectional relationship between obesity and oral health, limited studies have examined this association in adolescent populations, particularly in Syria. This study aimed to investigate the relationship between body mass index (BMI) and oral h

ealth indices, including gingival index (GI), plaque index (PI), and decayed, missing, and filled teeth (DMFT) index, among adolescents aged 12-14 years in Damascus, Syria.

Materials and Methods: In this …

Efficiency And Clinical Outcomes Of Platelet-Rich Plasma Therapy On Canine Coxofemoral Osteoarthritis, Patama Arunrattanakul, Kumpanart Soontornvipart

The Thai Journal of Veterinary Medicine

The purpose of this study was to find out the optimal technique to prepare plasma with the highest platelet concentration in platelet rich plasma (PRP), as well as determine the result of autologous PRP from the dogs with osteoarthritis (OA) condition. It was shown that the PRP could reduce inflammation, cell regeneration and enhance angiogenesis to support the injured tissue. This study was composed of two phases; the first phase aimed to find the best centrifugation speed and time that could be able to produce the plasma with the highest platelet concentration by conducting the experiment from a total of …

The Effect Of The Actn3 Gene Variation On Physically Active Individuals' Susceptibility To Muscle Injury, Agata Leońska-Duniec, Piotr Kabelis, Agata Rzeszutko-Bełzowska

Baltic Journal of Health and Physical Activity

Background: The R577X polymorphism (rs1815739) in the ACTN3 gene, which encodes α-actinin-3, results in deficiency of the functional protein in the muscles of the XX carriers, what could potentially impair muscle fiber function and increase susceptibility to injuries. Thus, this study aimed to assess the relationship between the ACTN3 R577X polymorphism and non-contact muscle injury risk in a physically active Caucasians cohort. Mate-rials and Methods: The study included 142 physically active individuals (26 females and 116 males) who experienced either single (n = 26) or multiple (n = 116) non-contact muscle injuries. The control group included 163 participants (47 females …

Effect Of Pitch Dimensions On External Load Measures During Large-Sided Soccer Games: Manipulating Pitch Size To Control Load, Alireza Rabbani, Robert Trybulski, Filipe Manuel Clemente

Baltic Journal of Health and Physical Activity

Background: The aims of this study were to examine the variability and differences of selected external load metrics during soccer large-sided games (LSGs) depending on the pitch size. Materials and methods: The external load metrics of 13 male soccer players were monitored during 14 sessions. These metrics included total distance (TD), high-intensity running distance (HIR) (meters covered with speed >14.4 km^.h^-1), high-speed running distance (HSR) (meters covered with speed >19.8 km^.h^-1), high-metabolic load distance (HMLD), mechanical work (MW) (the sum of accelerations and decelerations >3 m²), maximal velocity (Max V) …

Investigating The Market Dynamics Of Aeroponically Cultivated Products With Delay, Pulak Kundu, Uzzwal Kumar Mallick

Mathematical Modelling and Numerical Simulation with Applications

Aeroponically grown potatoes offer higher yields and year-round production but often face delayed market entry due to high setup costs, technical barriers, and logistical challenges. A delay-based mathematical model has been newly proposed in this study to analyze the dynamics of demand, supply, and pricing for aeroponically grown products. The model’s existence, stability, and sensitivity have been investigated analytically, and numerical simulations have been carried out using the Runge-Kutta 4th order method with the dde23 solver. Findings reveal that market stability is maintained when delays are below seven years, but delays beyond this threshold lead to persistent fluctuations in price, …

The Saltpond Oilfield’S Second Life: Ghana’S Bioenergy With Carbon Capture And Storage (Beccs) Opportunity, Justice Appiah Nuamah

COP30

As the achievement of net-zero emissions requires the unavoidable deployment of Carbon Dioxide Removal (CDR) technologies, this paper presents a technical and policy case for Ghana to implement Bioenergy with Carbon Capture and Storage (BECCS) through the repurposing of the decommissioned Saltpond offshore oilfield for permanent CO2 sequestration. The proposal addresses two of Ghana’s developmental challenges in a single intervention: the conversion of millions of tonnes of agricultural and forestry residues into a sustainable feedstock solves a national waste management issue, while the resultant bioenergy generation supports rural electrification. This approach offers a more cost-effective CDR pathway than direct air …

Methodology Of Market Definition: Case Of Digital Multi-Sided Platforms, Anzhelika Gerasymenko, Vasyl Hanovskyi

Yearbook of Antitrust and Regulatory Studies

The rapid expansion of the digital economy has significantly contributed to the increasing market power of digital multi-sided platforms, making its precise measurement increasingly challenging. The main reason is the lack of efficiency of SCP-tools in digital markets that push competition authorities to look for alternative ways of competition regulation in such markets (like the DMA approach), while its results are still poor. This paper provides the methodological grounding of a vertical breakdown of a complex product traded by digital multi-sided platforms to bring back the conventional tools of market definition and to adjust them to the specifics of digital …

Mcmc-Net: Accelerating Markov Chain Monte Carlo With Neural Networks For Inverse Problems, Anuj Abhishek

Faculty Scholarship

In many computational problems, using the Markov Chain Monte Carlo (MCMC) can be prohibitively time-consuming. We propose MCMC-Net, a simple yet efficient way to accelerate MCMC via neural networks. The key idea of our approach is to substitute the true likelihood function of the MCMC method with a neural operator based surrogate. We extensively evaluate the accuracy and speedup of our method on three different partial differential equation-based inverse problems where likelihood computations are computationally expensive, namely electrical impedance tomography, diffuse optical tomography, and quantitative photoacoustic tomography. MCMC-Net performs similar to the classical likelihood counterpart but with a significant speedup. …

Faktor-Faktor Yang Berhubungan Dengan Gejala Depresi Pada Pasien Insomnia Usia Lanjut Di Rawat Jalan, Amalia Nur Pratiwi, Edy Rizal Wahyudi, Profitasari Kusumaningrum, Hamzah Shatri, Ikhwan Rinaldi, Rino Alvani Gani, Ika Prasetya Wijaya, Adityo Susilo, Kaka Renaldi

Jurnal Penyakit Dalam Indonesia

Introduction. The elderly population is increasing globally, including in Indonesia, where 10.7% of the population in 2020 were elderly. Insomnia is a common health issue among older adults and has been identified as a predictor of depression. This study aims to identify factors associated with depressive symptoms in elderly outpatients with insomnia.

Methods. This cross-sectional study was conducted in 2024 on patients aged ≥60 years at the outpatient unit of Cipto Mangunkusumo Hospital (RSCM), Jakarta, Indonesia, using consecutive sampling to select participants. Elderly patients were screened using the Pittsburgh sleep quality index (PSQI), and those with a score …

From Black Umay To Albasti And From Yellow Girl To Martu: Reflection Of Evil Spirits In Uzbek Folklore, Dilbar Haydarova

Khazar Journal of Humanities and Social Sciences

Binary moral cosmologies—from Yin–Yang and Zoroastrian dualism to the God–Devil polarity—have long organized Eurasian thought. Uzbek oral literature participates in this horizon through persistent figures of benevolent and malevolent spirits that aid or obstruct heroic protagonists. To trace the historical development and literary functions of iyes (protective spirits) and yeys (harmful spirits) in Uzbek Turkic belief and narrative, and to identify their survivals in contemporary everyday practice. The study integrates close readings of canonical epics and folktales with comparative Central Asian and Islamicate folkloristics, supported by etymological analysis and targeted ethnographic notes. A diachronic typology is constructed to map motifs, …

Adultery And Infidelity: A Comparative Study Of Kate Chopin’S The Awakening And Halit Ziya Uşaklıgil' S AşK-I Memnû (Forbidden Love), Fikret Güven

Khazar Journal of Humanities and Social Sciences

Kate Chopin’s The Awakening (1899) and Halit Ziya Uşaklıgil’s Aşk-ıMemnû (Forbidden Love, 1900) explore the oppressive gender expectations placed upon women in their societies of late 19th-century Louisiana Creole and Ottoman Istanbul. Despite their cultural and geographical differences, both novels depict heroines who are seeking personal autonomy and emotional fulfillment. However, they ultimately succumb to the rigid constraints of patriarchy. Edna Pontellier and Bihter Ziyagül embark on transformative journeys that challenge prescribed gender roles through extramarital relationships, yet their desires for independence are met with societal condemnation. Edna’s rebellion stems from self-discovery and existential awakening, whereas a quest for passion …

Dark Laughter In Uniform: Humor And Militarism In Gregory Burke’S Black Watch, Pelin Gölcük Mirza

Khazar Journal of Humanities and Social Sciences

Gregory Burke’s Black Watch, which premiered at the 2006 Edinburgh International Festival, focuses on the experiences of Scottish soldiers deployed to Iraq in 2003. The play makes extensive use of dark humor by juxtaposing laughter and pain, valor and absurdity, military and civilian life, in order to reveal the contradictions of contemporary militarism. Rather than celebrating patriotism or sacrifice, Burke undermines the romanticized narratives of heroism through profanity, abrupt shifts in tone, and mock-heroic scenes. Dark humor, thus, functions as both a coping strategy for soldiers’ trauma and a satirical device that subverts political rhetoric about the war. By …

Beyond The Bedside: How Interdisciplinary Rounds Streamline Icu Care And Transitions, Kristina Boudreau, Sarah Beldin, Gillian Grafton, Ryann Lair

2025 Nursing Research Symposium

No abstract provided.

Combating Workplace Violence: The Implementation Of A Behavioral Emergency Response Team, Jessica Schmidt, Jennifer Rice

2025 Nursing Research Symposium

No abstract provided.

Multidisciplinary Accountability In Fall Prevention, Crystie Mawyer

2025 Nursing Research Symposium

No abstract provided.

No Need To Restrain, Gab A Mitt, And Refrain!, Jessica Schmidt, Jennifer Rice

2025 Nursing Research Symposium

No abstract provided.

No One Dies Alone, Jessica Schmidt, Jennifer Rice

2025 Nursing Research Symposium

No abstract provided.

Preventing Workplace Violence: Implement A Behavioral Emergency Response Team Leveraging Existing Resources, Hannah M. Musgrove, Katie Witherspoon, Eman Chami

2025 Nursing Research Symposium

No abstract provided.

Stepping Towards Healing: The Impact Of Early Mobility In The Icu, Kelly M. Miller, Kimberly Rizkallah

2025 Nursing Research Symposium

No abstract provided.

Under Pressure: Isolating The Data For Prevalence And Severity Of Pressure Injuries In Isolation Rooms, Jessica Schmidt, Nichole White, Audrey Rutkowski, Emilee Losey

2025 Nursing Research Symposium

No abstract provided.

Nursing Trust Program: An Avenue Of Support For The Clinical Nurses Who Are Second Victims, Nancy Price, Cathy Draus, Sharron Alejandria, Amanda Delucia

2025 Nursing Research Symposium

No abstract provided.

Stress Less, Nurse Strong, Kimberly Foster

2025 Nursing Research Symposium

No abstract provided.