Digital Commons Network^™

Distinct Intrinsic And Extrinsic Factors Differentially Regulate Skeletal Stem Cells In Calvaria Versus Long Bones During Bone Regeneration, Jea Solidum, Kohei Yamasaki, Youngjae Jeong, Laura Ortinau, Francisco Heralde, Dongsu Park

Faculty, Staff and Students Publications

Calvarial suture skeletal stem cells (Su-SSCs) are a distinct stem cell population for craniofacial bone formation by intramembranous ossification, compared to long bone periosteal SSCs (LB-PSSCs) with endochondral (osteochondrogenic) ossification. However, whether SSC intrinsic or extrinsic factors affect their differentiation process has not been well elucidated. Here, using an inducible Prx1-CreER-EGFP+/−;Rosa26-tdTomato mouse model, we observed that endogenous Prx1+ Su-SSCs and their orthotopic transplantation into calvarial injury do not form cartilage intermediates at the injury sites, while the transplantation of Prx1+ LB-PSSCs into LB injury induces osteochondrogenic differentiation, respectively. However, the heterotopic transplantation of Prx1+ Su-SSCs (Su-SSCs …

The Emerging Role Of Osteopathic Manipulative Medicine In Enhancing Quality Of Life For Palliative And End-Of-Life Patients: A Narrative Review, Ambrose Loc T. Ngo, Linda Nguyen, Cynthia Shahbandeh, Jared W. Nichols

Student Publications

Palliative and end-of-life care aim to minimize suffering and optimize the quality of life for individuals nearing the end of their lives. Osteopathic manipulative medicine (OMM) represents a potentially valuable nonpharmacological approach within this integrative care framework. Emerging evidence from clinical observations, small-scale studies, and foundational osteopathic principles suggests that OMM may help support patient comfort, alleviate certain symptoms, and contribute to dignity in care. Techniques such as myofascial release, cranial manipulation, and lymphatic drainage have been reported to improve comfort and emotional well-being; however, these findings are based primarily on limited and heterogeneous studies. This narrative review synthesizes current …

Identifying The Big Questions In Paleontology: A Community-Driven Project, Tracy Aze

School of Biological and Marine Sciences

Paleontology provides insights into the history of the planet, from the origins of life billions of years ago to the biotic changes of the Recent. The scope of paleontological research is as vast as it is varied, and the field is constantly evolving. In an effort to identify “Big Questions” in paleontology, experts from around the world came together to build a list of priority questions the field can address in the years ahead. The 89 questions presented herein (grouped within 11 themes) represent contributions from nearly 200 international scientists. These questions touch on common themes including biodiversity drivers and …

Space: The Final Frontier (For State Power): The History Of The East India Company And The Future Of Outer Space, Richard Culbert

International Law Studies

Outer space may be the last domain where States largely lack the capability to use coercive force as an instrument of State control. In all areas of the globe, major powers have militaries and police forces that far exceed the capability of even the largest corporations. As corporations take an increasingly large role in outer space commerce it is likely that these private actors will develop a capacity to use force that quickly surpasses even the most powerful States.

To date there has been little analysis of this future phenomenon by legal scholars. Perhaps as a result, the current international …

Prospective Associations Among Loneliness And Health For Servicemembers: Perceived Helplessness And Negative Coping Appraisal As Explanatory Mechanisms, Sarah N. Arpin, Cynthia D. Mohr, Todd Bodner, Leslie B. Hammer, James D. Lee

Psychology Faculty Publications and Presentations

Links between loneliness and health are robust, though evidence for associations with alcohol use is mixed. Previous research has supported perceived stress as a predictor of alcohol use and as a pathway through which loneliness impacts health over time. Yet findings are primarily limited to civilian samples, and less is known about how loneliness relates to stress and health among service members. The current study explores prospective associations among loneliness, stress, and health (i.e., sleep, alcohol misuse, and psychological distress) within a sample of mostly male service members. We examine two dimensions of perceived stress, perceived helplessness and negative coping …

A Rural Ministry Helping Adults With Intellectual Or Developmental Disabilities Meet Their Vocational Goals: A Case Study Of The Canteen And Trading Post (Ctp), Julie Byford Harstin

Electronic Theses and Dissertations Archive

This study's purpose was to describe and evaluate the Canteen & Trading Post’s (CTP’s) approach to workforce education for adults with intellectual or developmental disabilities (AIDD) and CTP participants’ perceptions of AIDD’s employability in their rural community. A qualitative study method was used, including semi-structured interviews, arts-based research, and participant-observation. The guiding research questions for the study were: 1. How is the Canteen & Trading Post helping adults with intellectual or developmental disabilities meet their vocational goals?, 2. How are AIDD's needs for accommodation changing through their experiences at the CTP?, and 3. How is the CTP demonstrating AIDD’s employability …

Cfd Modeling Of Lateral Spillway Flow In End-Of-Bridge Deck Drainage, Serox Sukupayo

Electronic Theses and Dissertations Archive

The Tennessee Department of Transportation (TDOT) has established a new standard for bridge-deck drainage, which features a side-inlet positioned at the end of the bridge adjacent to the roadway. This inlet serves as a lateral weir or spillway, connecting to a riprap-lined flume or chute that extends down the embankment. The hydraulic performance of this standard - encompassing capture efficiency, bypassed flow, water spreads and depths on the pavement, flow depths and velocities in the flume, and the potential for embankment erosion - must be evaluated across a variety of bridge conditions, including longitudinal and cross slopes, as well as …

Metaphor Use In Indonesian Scholars' Talk About Migration, Heri Yusup

Electronic Theses and Dissertations Archive

Despite the growing body of research on the use of metaphors to discuss personal experiences during complex and challenging situations (such as during the COVID-19 pandemic or related to life-threatening illnesses), metaphor analysis is rarely employed to examine how certain individuals use metaphors to talk about their migration experiences. Extensive studies on metaphorical framing of migration have been conducted. However, private discourse is rarely the subject of these studies. Furthermore, metaphor research incorporating conceptual metaphor theory as its theoretical framework seldom underscores the intersection of metaphorical conceptualization and identity construction. Therefore, this dissertation examines the conceptual metaphors used by individuals …

Perceptions Of Black Male Alternative High School Students' Disciplinary Experiences A Qualitative Narrative Inquiry Study, Rahmod Traylor

Electronic Theses and Dissertations Archive

The current study examines how Black male students in alternative high school settings interpret and describe their disciplinary experiences and educational trajectories. Guided by Culturally Sustaining Pedagogy (CSP) as the theoretical framework and Narrative Inquiry as the methodological approach, the research investigates how cultural identity, systemic inequities, and school-based disciplinary practices intersect in shaping students’ academic pathways. The study addresses two central questions: (1) How do the educational experiences of Black males who graduated from alternative high schools differ from those who did not? (2) In what ways do culturally sustaining pedagogical practices inform or fail to inform these experiences? …

Aging In Mice Alters Regionally Enriched Striatal Astrocytes, Kay E Linker, Violeta Duran-Laforet, Matthias Ollivier, Xinzhu Yu, Dorothy P Schafer, Baljit S Khakh

Faculty, Staff and Student Publications

Aging affects multiple organs and within the brain drives distinct molecular changes across different cell types. The striatum encodes motor behaviors that decline with age, but our understanding of how cells within the striatum change remains incomplete. Using single-cell RNA sequencing from young and aged mice we identify molecularly distinct astrocyte subtypes. We show that astrocytes change significantly with age, exhibiting downregulation of genes, reduced diversity, and a shift to more homogenous inflammatory transcriptomic profiles. By exploring where striatal astrocyte subtypes are located with single-cell resolution, we map astrocytes enriched in dorsal, medial, and ventral striatum. Age increases inflammatory marker …

Hawc, Veritas, Fermi-Lat, And Xmm-Newton Follow-Up Observations Of The Unidentified Ultra-High-Energy Gamma-Ray Source Lhaaso J2108+5157, C. B. Adams, P. Bangale, W. Benbow, J. H. Buckley, Y. Chen, J. L. Christiansen, S. Groetsch, P. Hüntemeyer, M. Najafi, R. Turner, X. Wang, Et. Al

Michigan Tech Publications

We report observations of the ultra-high-energy gamma-ray source LHAASO J2108+5157, utilizing VERITAS, HAWC, Fermi-LAT, and XMM-Newton. VERITAS has collected ∼40 hr of data that we used to set ULs to the emission above 200 GeV. The HAWC data, collected over ∼2400 days, reveal emission between 3 and 146 TeV, with a significance of 7.5σ, favoring an extended source model. The best-fit spectrum measured by HAWC is characterized by a simple power law with a spectral index of 2.45 ± 0.11stat. Fermi-LAT analysis finds a point source with a very soft spectrum in the LHAASO J2108+5157 region, consistent with the 4FGL-DR3 …

Legal Realism, Legal Positivism, And Determinacy, Dan Priel

All Papers

It is a commonplace that the legal realists argued that law is deeply indeterminate. According to this familiar account, the legal realists insisted that legal materials don’t constrain judges, who are therefore free to decide cases in almost any way they want. An influential argument has argued that the only way to explain this view is by showing that the legal realists presupposed a legal positivist theory of law. This Essay offers a different understanding of the relationship between realism, positivism, and determinacy, challenging this interpretation of the realists as both historically false and as philosophically unwarranted. I provide many …

Polymorphism Crystal Structure Prediction With Adaptive Space Group Diversity Control, Sadman Saadeed Omee, Lai Wei, Jianjun Hu

Faculty Publications

Crystalline materials can form different structural arrangements (i.e., polymorphs) with the same chemical composition, exhibiting distinct physical properties depending on how they are synthesized or the conditions under which they operate. For example, carbon can exist as graphite (soft, conductive) or diamond (hard, insulating). Computational methods that can predict these polymorphs are vital in materials science, which help understand stability relationships, guide synthesis efforts, and discover new materials with desired properties without extensive trial-and-error experimentation. However, effective crystal structure prediction (CSP) algorithms for inorganic polymorph structures remain limited. ParetoCSP2 is proposed, a multi-objective genetic algorithm for polymorphism CSP that incorporates …

Pendant Micro-Droplet Evaporation Fabricates Fiber-Optic Mof Gas Sensor In Seconds, Abhishek Prakash Hungund, Bohong Zhang, Narasimman Subramaniyam, Thomas Spudich, Ryan O'Malley, Farhan Mumtaz, Rex E. Gerald, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

The development of photonic-based gas sensors using metal–organic frameworks (MOFs) and other microporous solids is often a multistep, complex process, typically involving MOF synthesis, purification, and attachment of microcrystals to an optical fiber end face. This study introduces a one-step method that integrates MOF synthesis and sensor head fabrication directly onto the fiber end face, forming an extrinsic Fabry–Perot interferometer (EFPI) with a thin film of MOF microcrystals. The resulting film, only 3–10-μm-thick, enhances sensor response by enabling rapid gas detection within seconds. Utilizing a pendant micro-droplet evaporation technique, this method forms a microporous MOF layer in situ, allowing unreacted …

The Power Of The Mind: Managing Dental Phobia Through Hypnotherapy, Casper Jonker, Ness Avery, Jim Carey

Peninsula Dental School

Treatment of dental disease is documented since ancient times. According to some sources, there is evidence that civilisations including the Egyptians, Greeks, and early Chinese were already practising dentistry. Teeth were extracted, primitive restorations placed and ways were even found to construct basic forms of dental prostheses.1 Interestingly, a team of experts determined that as far back as 9,000 years ago, people were able to remove ‘rotting' dental tissue and there is evidence of drilling on an area near an abscess. Since these early days of dentistry, it has evolved tremendously in all facets of the profession.

Unraveling Crop Nitrogen-Water Dynamics With Hyperspectral-Thermal Sensing In Northern Central Valley, California, Shahryar Fazli, Surendra Maharjan, Wenzhao Li, Joshua B. Fisher, Rejoice Thomas, Fernando Romero Galvan, Gabriela Shirkey, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Ensuring global food security in the face of climate change requires optimizing crop water use and nutrient management. This study investigates the relationship between canopy nitrogen (N) and evapotranspiration (ET) across sunflower, rice, walnut, alfalfa, and plum crops using advanced remote sensing technologies. High-resolution hyperspectral data from NASAs Earth Surface Mineral Dust Source Investigation (EMIT) and thermal multispectral data from the Landsat-based OpenET system were analyzed over 1,135 km² in California. Regression analysis revealed strong spatial association between canopy N and ET for sunflower (R² = 0.82), rice (R² = 0.71), and walnut (R² = 0.68), …

Multi-Wavelength Study Of 1erass J085039.9−421151 With Erosita, Nustar, And X-Shooter, A. Zainab, A. Avakyan, V. Doroshenko, P. Thalhammer, E. Sokolova-Lapa, R. Ballhausen, N. Zalot, J. Stierhof, S. Hämmerich, C. M. Diez, P. Weber, T. Dauser, K. Berger, P. Kretschmar, K. Pottschmidt, Pragati Pradhan, N. Islam, C. Maitra, J.B. Coley, P. Blay, R.H.D. Corbet, R.E. Rothschild, K. Wood, A. Santangelo, U. Heber, J. Wilms

Publications

The eROSITA instrument on board Spectrum-Roentgen-Gamma (SRG) has completed four scans of the X-ray sky, leading to the detection of almost one million X-ray sources in eRASS1 alone, including multiple new X-ray binary candidates. We report on analysis of the X-ray binary 1eRASS J085039.9−421151, using a ∼55 ks long NuSTAR observation, following its detection in each eROSITA scan. An analysis of the eROSITA and NuSTAR X-ray spectra in combination with X-shooter data of the optical counterpart provide evidence of an X-ray binary with a red supergiant (RSG) companion, confirming previous results. However, we did determine a cooler spectral type for …

An Innovative And Equitable Approach For Global Learning: Internationalization At Home, Unni Jenssen, Tracy Taylor, Sara Edwards, Jeanie M. Bochenek

International Nursing Research Congress (INRC)

In an era of increasing global connectivity and cultural diversity, fostering cultural competence among students is paramount. It is a prevailing notion that cultural competence is primarily achieved through international mobility. However, the reality is that most students are unable to travel abroad due to economic limitations, family obligations and work commitments. With these limitations of international mobility, innovative strategies to enhance cultural competence “at home” were developed by Lovisenberg Diaconal University College (LDUC) in Norway and Ohio State University College of Nursing in Ohio. Grounded in Campinha-Bacote’s model of cultural competence, these strategies include a) systematic integration of domestic …

Blending Virtual Learning And Travel Abroad As Teaching Strategies To Develop Global Perspectives, Tracy Taylor, Unni Jenssen, Jeanie M. Bochenek, Sara Edwards

International Nursing Research Congress (INRC)

In 2022, there were 2.8 million undergraduate students in the U.S. About 6% studied abroad, leaving 94% of students without exposure to global perspectives. To enable global learning for nursing students, Ohio State University College of Nursing in Ohio and Lovisenberg Diaconal University College in Norway developed a common course on urban health whereby two separate teaching strategies were used: travel abroad to Norway/U.S. and “at home” collaborative online international learning (COIL). The purpose of these strategies is to connect COIL students with travel abroad students in both countries to enhance global learning.

In spring of 2024 prior to starting …

Linking International Students In An Exchange To Create Global Learning, Sara Edwards, Jeanie M. Bochenek, Tracy Taylor, Unni Jenssen

International Nursing Research Congress (INRC)

As globalization around the world increases, creating meaningful international experiences for students is essential in higher education. Preparing nursing students with knowledge and skills to successfully interface and care for diverse populations equips them to provide culturally competent quality care.

The purpose of this exchange was for faculty from Ohio State University (OSU) College of Nursing in Ohio and Lovisenberg Diaconal University College in Norway to collaborate, develop, and provide students with culturally rich experiences that mirrored students internationalizing at home or traveling abroad. Students’ learning experiences focused on community health care settings, common health concerns and resources that support …

Developing Empathy For Homelessness Populations Through A Virtual Reality Teaching Strategy, Jeanie M. Bochenek, Sara Edwards, Unni Jenssen, Tracy Taylor

International Nursing Research Congress (INRC)

Homelessness is a complex and growing public health concern encompassing 1.6 billion people globally. People living homeless face barriers in managing activities of daily living, existing chronic or acute health conditions, and are likely to experience more health problems and health inequities. Worldwide, nurses will encounter patients who are living homeless, therefore having an overall understanding of living homeless will help them care for their patients.

To give students a broader perspective, faculty from Ohio State University College of Nursing in Ohio and Lovisenberg Diaconal University College in Norway connected students to discuss a global health concern. The purpose of …

Integrating Genomics Into Nursing Education, Sarah Dewell, Trina Walker, Patricia Birch, Carol Cremin, Colleen Guimond, Leah P. Macfadyen

International Nursing Research Congress (INRC)

Precision health aims to tailor care for each person by incorporating genomic data and other biological information with relevant environmental, behavioural, and social determinants of health. Nurses, the largest healthcare profession globally and experts in the provision of personalized, holistic care, have a vital role in safe, quality, evidence-based precision healthcare (Dewell et al., 2024). To fully participate, nurses require an understanding of genomics relevant to their practice (Campion et al., 2019). However, integration of genomics into nursing curricula is highly variable (Calzone et al., 2018). This is in part due to lower levels of genomic knowledge among nursing faculty …

Global Progress Of Genomics Nursing Education Through Competence In Academic-Practice Partnerships, Deborah O. Himes, Ruth Lucas, Jennifer Dungan, Sarah Davis, Sarah Dewell

International Nursing Research Congress (INRC)

As healthcare transitions into the genomic era, nurses play a critical role in delivering quality, genomics-informed care. To achieve this, nursing education must address both the scientific foundations of genomics and the ethical, legal, and social considerations of its application. Despite this need, research identifies gaps in nurses’ knowledge and confidence to provide genomics-informed care and in educators’ ability to integrate genomics content into curricula (Thomas et al., 2023). Academic nurse educators globally have expressed need and desire for collaboration to improve genomics nursing education (Abad & Sur, 2022; Chair et al., 2019).

In response, the International Society for Nurses …

A Global Overview Of The Integration Of Genomics Into Nursing, Sarah Dewell, Emma Tonkin, Kathleen A. Calzone, Andrew Dwyer, Laurie Badzek

International Nursing Research Congress (INRC)

Across the globe, genomics is being applied into research and clinical practice initiatives to improve patient outcomes and decrease system costs (Stark et al., 2019). Genomics can enable earlier disease detection, guide treatment, inform prognosis, and advise preventative care (Claussnitzer et al., 2020). Nurses are the largest component of the health workforce and are instrumental in delivering genomics-informed care (Tonkin et al., 2020). However, most nurses have little to no training in genomics driven by a lack of global nursing competencies in genomics (Thomas et al., 2023). Despite this, many countries are taking action to prepare their nursing workforce for …

Relationship Between Personal Resilience And Organizational Resilience In Multidisciplinary Team, Nihal Khatib

International Nursing Research Congress (INRC)

Background: This study examined the response of multidisciplinary medical teams in Israel's healthcare system during the Israel-Gaza War that began on October 7, 2023, focusing on the Haifa and Western Galilee district. The research analyzed the relationships between personal and organizational resilience and their impact on medical team functioning across diverse populations.

Objectives: The study aimed to investigate the relationship between employees' personal and organizational resilience and their effects on performance during crisis. It sought to identify factors influencing resilience and performance, and to develop an intervention program for adaptation and crisis management.

Methods: An anonymous questionnaire was administered, incorporating …

Reflection And Appreciation: A Journey To Improving Care For Older Adults After Critical Illness, Cheryl Chia-Hui Chen

International Nursing Research Congress (INRC)

With 25 years of research, my work has focused on improving outcomes for critically ill older adults by addressing delirium, frailty, malnutrition, and functional decline. I’ve advocated for care bundles to prevent complications and support recovery. In this International Nurse Researcher Hall of Fame session, I’ll share my journey to advancing care for older adults after critical illness. This award is humbling and reflects the collective efforts of my colleagues, mentors, and students.

Building A Program Of Research To Improve Communication And Care For Older Adults, Kristine N. Williams

International Nursing Research Congress (INRC)

Upon Induction to the Sigma International Nurse Researcher Hall of Fame, Dr. Williams presented the development of her program of research focused on improving communication and care for older adults.

Bibliotherapy For Enhancing The Mental Well-Being Of Informal Caregivers Of People With Dementia, Shanshan Wang

International Nursing Research Congress (INRC)

This project is designed to investigate the potential of bibliotherapy as a self-help intervention for informal caregivers of individuals with dementia. A series of studies were carried out to examine its feasibility and efficacy in improving mental health and enhancing caregiving appraisal among informal caregivers of people with dementia, emphasizing its potential for broad implementation following successful clinical trials.

Researching Unheard And Silenced Voices, Vanessa Heaslip

International Nursing Research Congress (INRC)

Around 32% of the global population are at risk of social exclusion (Cuesta et al., 2024). This has significant impact upon morbidity, mortality and quality of life (Aldridge et al., 2017). In research, these individuals are underserved (NIHR 2024), perceived to be ‘difficult’, ‘hard to reach’ or in need of protection, so their voices and experiences remain unheard. This keynote shall explore some of these challenges, share ideas and explore ways to promote inclusive research.

Adaptation And Resilience In Families Of Individuals With Down Syndrome, Marcia L. Van Riper

International Nursing Research Congress (INRC)

The purpose of this presentation is to highlight key findings from my program of research concerning families of individuals with Down syndrome. Early studies with these families predominantly focused on problems and deficits, while my work highlights the strengths and resilience these families often exhibit. My program of research has contributed to a more nuanced understanding of these families by emphasizing the dynamic processes that enable families to adapt successfully to adversity.