Digital Commons Network^™

Sulforaphane And Non-Clustered Tumor/Non-Tumor Suppressor Micrornas Regulate Akt And Its Downstream Genes In Mda-Mb-231 Cancer Cells, Omobolanle David Garuba

Dissertations (2016-Present)

Cancer is a complex pathological condition characterized mainly by uncontrolled rapid cell divisions caused by several factors, which include genetics and environmental factors. Of all cancer types, breast cancer (BC) remains the second most diagnosed among women worldwide; thus, BC burden has become a global health issue. Of all known breast cancer subtypes, triple-negative breast cancer (TNBC) is the only primary subtype without effective therapy as a result of their lack of the essential estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) common to other BCs and are the usual therapeutic targets for treatment. …

Detection Of Microplastics In Household Dust From Suburban Texas And Toxicological Assessment Of Polystyrene Microparticles In Lung Epithelial Cells: Nf-Kb Pathway Activation And Inflammatory Responses, Nirupama Surubhotla

Dissertations (2016-Present)

Microplastics are emerging contaminants that have raised global concern due to their persistence, ubiquity, and potential impacts on human health. Indoor environments are increasingly recognized as significant sources of microplastic exposure through household dust inhalation. This study aimed to detect the presence of microplastics in household dust from suburban regions of Texas, USA, and to investigate the cytotoxic and inflammatory effects of polystyrene microparticles in a lung epithelial cell model (A549). Household dust samples were collected and analyzed using Raman spectroscopy, confirming the presence of a mixture of microplastics. To assess biological responses, A549 cells were exposed to defined sizes …

University Of San Diego Magazine Fall 2025, Publications Department

University of San Diego Magazine (1992- )

Beauty, Goodness and Truth; Dear Toreros; Around Alcalá Park; At The Edge of It All; Faith In Action; Torero Spotlight; Torero Athletics; Toreros Making Waves; In Memoriam; Leading With Love

The Access Assembly: Learning Together, Building Friendships, And Strengthening Our Leadership Capacities, Chandra Turpen, Brianne Gutmann, Robert P. Dalka, Gina M. Quan, Mackenzie Carlson, Joel C. Corbo, Gabrielle Jones-Hall, Megan Marshall Smith, Devyn E. Shafer

Faculty Research, Scholarly, and Creative Activity

Founded in 2014, the Access Network brings together nine student-centered, university-based programs that pursue systemic change towards a vision of a more diverse, equitable, inclusive, and accessible STEM community. Leaders at the Network-level and program-level are either current students (undergraduate or graduate) or young faculty and professional scientists, many of whom started out as student leaders in Access programs. Over the last 9 years, Access has brought people together (virtually or in-person) for an annual event called the "Assembly." Student leaders who attend the Assembly appreciate community-building and networking opportunities that help them build capacity for leading local site programming. …

The Access Assembly: Sharing Ideas And Enabling Informed Adaptations, Brianne Gutmann, Chandra Turpen, Robert P. Dalka, Mackenzie Carlson, Joel Corbo, Gabrielle Jones-Hall, Megan Marshall Smith, Devyn Shafer

Faculty Research, Scholarly, and Creative Activity

Founded in 2014, the Access Network brings together nine student-centered, university-based programs that are pursuing systemic change towards a vision of a more diverse, equitable, inclusive, and accessible STEM community. Network and program leaders are primarily students (undergraduate and graduate) and early-career faculty, many of whom started out as student leaders in Access programs. Over the last nine years, Access has brought people together (virtually or in-person) for an annual event called the “Assembly.” The environment and structures at the Assembly enable the sharing of ideas, excite people to translate those ideas to their local programs, and create space for …

Southeast Asia Higher Education Changes And Emerging Futures, Muhammad Hali Aprimadya, Lily Kong, Angel Calderon, Hamish Coates

Research Collection School of Social Sciences

This paper unpacks recent developments and future directions in Southeast Asian higher education. It takes stock of higher education systems in three selected countries, Australia, Indonesia and Singapore. It sketches these systems, distils several changes around 2024, and discusses emerging directions for education, research and universities. The paper concludes by looking at what is required to catalyse transformations likely to impel future progress.

Decoding Influence: Cosmetic Industry Strategies, Media Beauty Standards, And Their Mental Health Impact On Generation Z Consumers, Tatiana Avila Velasquez

Undergraduate Theses and Capstone Projects

This research explores the complex relationship between cosmetic industry marketing strategies, media-driven beauty standards, and the mental health of Generation Z consumers. Utilizing both qualitative and quantitative methods, the study examines how frequent exposure to curated beauty ideals and persuasive advertising shapes self-esteem, confidence, and personal identity among young adults. Through surveys and in-depth interviews, the research highlights the evolving nature of cosmetic use, revealing how early engagement with beauty products often stems from social conditioning and personal insecurities. Participants describe a shift from using cosmetics as a means of concealment to embracing them for creative expression and self-care. However, …

Changes In Alcohol Consequences And Food Addiction Symptoms Over Time In A Diverse Sample Of Emerging Adults With Histories Of Heavy Drinking, Mary Takgbajouah

Theses and Dissertations from DePaul University

During Emerging Adulthood (EA; 18-29), alcohol use (AU) peaks and eating disorders tends to have their onset. While AU typically decreases by the end of EA, this can be a time of increased isolation and lead to problematic, ongoing use with significant, negative consequences, such as depression, anxiety, or poor sleep. Research has noted similarities between disordered overeating and substance use, resulting in the conceptualization of food addiction (FA). Less is known about trajectories of FA, particularly during EA. Trait impulsivity, a tendency to act without planning or thinking of potential consequences, is associated with problematic AU and FA. Research …

Decomposition And Excavation Of War Memories And Massacres In Na Hong-Jin’S The Wailing, Grace Jung

BCES: Faculty Publications

This chapter examines Korean filmmaker Na Hong-jin’s The Wailing (2016) as an allegory of South Korea’s unresolved colonial and Cold War traumas, arguing that the film’s deliberate ambiguity, cacophony, and generic instability reflect the difficulty of recovering histories of violence that have been suppressed, erased, or inadequately mourned. While scholarship on South Korean zombie cinema has frequently interpreted the zombie through neoliberal capitalism, economic crisis, contagion, and social alienation, this chapter locates the Korean zombie within a longer history of civil war, massacres, sexual violence, and authoritarian state repression. Drawing on Heonik Kwon’s concept of Cold War “decomposition,” the zombie …

Hooks For Four-Dimensional Ecology Education (4dee) Teaching With Differing Audiences Of Nonmajors, Sara E. Scanga, Vikki L. Rodgers, Loren B. Byrne, Justin R. St. Juliana, Jon M. Honea, Erica S. Tietjen, George Middendorf

Arts & Sciences Faculty Publications

Nonmajors (i.e., undergraduate students not majoring in the natural sciences) constitute a majority of United States college graduates and are a large potential audience for courses with ecology content. However, nonmajors may be unmotivated to learn about ecology because they perceive it to be uninteresting and irrelevant to their everyday lives or career goals. Although the Four-Dimensional Ecology Education (4DEE) framework can be adapted for nonmajors courses as a starting point to improve student engagement, we suggest that nonmajors ecology instructors also use ecology hooks as effective gateways to 4DEE that will motivate and deepen student learning. Selecting and developing …

Trickle-Down Coordination: The National Security Advisor’S Role As The Strategic And Operational Planner Of The Dod-Dos Interagency Relationship, Fabio S. Van Loon

Journal of Strategic Security

Forging a coherent U.S. foreign policy requires the competent management of the inter-agency framework. Defining strategy at the cabinet level and ensuring its implementation at the operational level, the National Security Advisor must act as an honest broker of the inter-agency process. This article will examine the role of three National Security Advisors from the Nixon, Carter and George W. Bush administrations, and study two examples of operational success and failure, highlighting the importance of the strategic-operational link. The author concludes by recommending a National Security Council (NSC)-led inter-agency framework that drives consensus-based strategic planning and mandates operational coordination through …

The Element Of Surprise: Highly Maneuverable Satellites And Ssa, Simone L. Montandon

Journal of Strategic Security

Military, commercial, and civil space missions rely on accurate space situational awareness (SSA) to avoid collisions and inform the analysis of the threat environment. Historically, man-made objects in space have been highly predictable because their trajectories were mostly constrained within the orbit they occupied. However, fast-paced progress in engine/thruster technology, energy efficiency, and on-orbit servicing and refueling have allowed satellites to maneuver often and quickly within their lifespan. This added an element of unpredictability that adds further uncertainty to an operational environment that is already highly uncertain. This paper argues that solving this issue will require pursuing continued custody of …

Identifying Signatures Of Unidentified Aerospace Phenomena Through Structured Analytic Techniques, Joshua S. Pierson, Ms, Dss

Journal of Strategic Security

Unidentified Aerospace Phenomena (UAP) penetrate sovereign airspace and sea space with such proliferation that often national security entities are left baffled with how to detect, identify, and respond to such actions. Since World War II, these phenomena were reported to pace aircraft, maneuver at high speeds in an erratic fashion and increase speed to hypersonic velocity when starting from stasis. The study of UAP is shrouded in stigma, perplexing government mishaps, and academic inquiry focusing on the material aspects of UAP, leaving a gap in determining the exhibited capability and intent of these phenomena. The use of structured analytic techniques …

Ai-Enabled Terrorism: A Strategic Analysis Of Emerging Threats And Countermeasures In Global Security, Shai Farber

Journal of Strategic Security

The rapid advancement of artificial intelligence (AI) is transforming terrorist methods and counter-terrorism strategies, with far-reaching effects on global security. This paper examines how terrorists use AI for new attack tactics, propaganda, and coordination, while also evaluating the ethical, legal, and strategic challenges AI introduces into counter-terrorism. Through a systematic literature review and qualitative analysis, the study identifies key trends in AI's impact on security dynamics, highlighting its role in blurring the lines between peace and conflict. An analytical framework is proposed to navigate the complex landscape of AI-driven asymmetric warfare, providing practical insights for policymakers and researchers. The study …

Detecting Drone Threats At Stadiums And Public Venues: Overview, Operational Considerations, And Technical Implementation, Nathan P. Jones, John P. Sullivan, George W. Davis Jr.

Journal of Strategic Security

This article overviews the issue of drone threats to stadiums and public venues. It provides emergency managers and those defending this critical infrastructure with an overview, operational considerations, and a discussion of the technical implementation for defending these sites from drone threats through detection. It provides a discussion of the current limitations of countermeasures and legal frameworks relevant to drones. Throughout, this article uses real drone detection data from the Astroworld concert incident (November 2021) as a notional case study to illustrate the type of drone detection data emergency managers will contend with and what can be gleaned from it. …

Management Of Recurrent Metastasis Of Renal Cell Carcinoma To The Parotid Gland After Nephrectomy., Kathryn Collins, Emily Cushing, Alex Ellerhorst, Christopher Selinsky

Oncology Articles

Renal cell carcinoma accounts for 90% of malignant renal tumors, with common metastases to the lungs, bones, and brain. Head and neck metastases are uncommon, and the parotid gland is an exceedingly rare site (0.5%). Recurrent metastasis to bilateral parotid glands has been reported in the literature, but recurrent metastasis to the ipsilateral gland has not. This is a case about a 69-year-old female who presented to our clinic with the chief complaint of a slowly enlarging left neck mass. She had a history of clear cell renal cell carcinoma treated with nephrectomy 15 years prior. An MRI reviewed from …

Redbird Scholar, Vol. 11, No. 1 (Fall 2025), Illinois State University, Office Of The Vice President For Research And Graduate Studies

Redbird Scholar

No abstract provided.

Tirzepatide For The Maintenance Of Body Weight Reduction: Rationale, Design, And Baseline Characteristics Of Surmount-Maintain, Deborah B Horn, Louis J Aronne, Sean Wharton, Harold E Bays, Elisa Gomez-Valderas, Avigdor D Arad, Palash Sharma, Julia P Dunn, Cagri Senyucel, Clare J Lee

Faculty, Staff and Student Publications

Objective: SURMOUNT-MAINTAIN aims to evaluate the efficacy and safety of reducing the tirzepatide dose and/or continuing the maximum tolerated dose (MTD) versus placebo in maintaining body weight (BW) reduction achieved with tirzepatide MTD.

Methods: This Phase 3b, multicenter, randomized, parallel-arm, double-blinded, placebo-controlled, 52-week clinical trial is in progress comparing treatment with once weekly tirzepatide (5 mg and/or MTD of 15 mg or 10 mg) versus placebo in achieving BW reduction maintenance from the initial 60-week open-label weight-loss period on tirzepatide MTD, in adults with obesity (BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 with ≥ 1 obesity-related comorbidity, excluding type …

Family History Of Substance Use And Stressful Life Events Impact Adolescent Maturation Of Cerebral White Matter, Yizhou Ma, Ashley Acheson, Corneliu Bolbocean, Mustafa N Mithaiwala, Si Gao, Neda Jahanshad, Paul M Thompson, Bhim M Adhikari, Xiaoming Du, A Ankeeta, Alia Warner, Antonio F Pagán, L Elliot Hong, Peter Kochunov

Faculty, Staff and Student Publications

Family history (FH) of substance use disorders (SUDs) and stressful life events (SLEs) are known risk factors for SUDs in adolescents and young adults. Cross‐sectional studies suggest that FH and SLEs affect adolescent white matter (WM) development and form abnormal WM patterns. Here, we examined the effects of FH, SLEs and their interaction on WM integrity in youths in the Adolescent Cognitive Brain Development (ABCD) study at baseline and 2‐ and 4‐year follow‐ups. ABCD youths (N = 8939, age ± SD = 9.9 ± 0.6 years, 4302 female) completed baseline diffusion tensor imaging, of which 5661 repeated the scan …

Tracking Change: A Follow-Up On The Culturally Adapted ¡Iniciando! La Adultez Program, Antonio F Pagán, Katherine A Loveland, Ron Acierno

Faculty, Staff and Student Publications

Introduction: Research on interventions for Latino young adults with Autism Spectrum Disorder (ASD) and their families often faces challenges in long-term engagement. This study aimed to assess the feasibility and effectiveness of the culturally adapted ¡Iniciando! La Adultez program through a long-term follow-up.

Methods: A cohort of Latino young adults with ASD and their families who participated in the ¡Iniciando! La Adultez program were followed for six months post-intervention. Participants were assessed at three and six months to evaluate continued engagement and outcomes. Retention rates at each follow-up point were calculated.

Results: The study demonstrated high retention rates, with 48 …

Community Firearm Violence And Dental Care Use In Middle Adulthood, Alexander Testa, Luis Mijares, Daniel Semenza, Richard Stansfield, Ian Silver, Dylan B Jackson, Ana Neumann, Jeff R Temple, Rahma Mungia

Faculty, Staff and Student Publications

Prior research links violence inside the home to reduced dental care utilization, yet little is known about how community firearm violence affects dental care behaviors. The current study used data from wave V (2016-2018) of the National Longitudinal Study of Adolescent to Adult Health (Add Health), linked to census tract-level fatal and nonfatal shooting data from the American Violence Project for the 100 largest cities in the United States. The analytic sample included 1925 respondents aged 33-42. The primary outcome was self-reported dental care use in the past year. Firearm violence exposure was categorized as 0, 1, or 2 + …

Addressing Climate Vulnerability And Policy Gaps Of Heat Waves In Upper Egypt: The Case Study Of Al-A’Qaab Village In Aswan, Eman Abdullah

Theses and Dissertations

Heatwaves are currently one of the most dangerous climate hazards globally. Egypt is experiencing an increase in the intensity and frequency of heatwaves, which affects health, economy, infrastructure, and the ecological system. Upper Egypt is one of the most vulnerable regions in Egypt to rising temperatures, particularly in Aswan Governorate. The risks of heat waves are increasing vulnerability among vulnerable groups, such as women and low-income individuals. However, there is a clear gap in protection policies against heat waves, along with a lack of studies examining the effects of heat waves on individuals in Aswan. Accordingly, this thesis aims to …

Seeing Is Believing: Identifying The “Ideal Manifestation Of Hidden Disability” In Ontario’S And Quebec’S Social Benefits Tribunals, Pascale Malenfant

Dalhousie Law Journal

The phenomenon of disability skepticism, especially in relation to “hidden” disabilities like chronic fatigue syndrome (CFS), has fostered a culture of doubt among medical, legal, and public entities. This paper explores the intersection of such skepticism with the social benefits adjudication processes in Ontario and Quebec. In drawing parallels to feminist critiques of the “ideal victim” in sexual assault cases, it argues that the tribunals’ biased framework for believability is based on a claimant’s conformity to stereotypical expectations of what an “ideal” claimant with a hidden disability looks like. By comparatively examining 10 years worth of Ontario and Quebec tribunal …

Misuse Of Financial Services For The Sexual Exploitation Of Children: A Socio-Legal Study In Indonesia, Ahmad Sofian

The Indonesian Journal of Socio-Legal Studies

This paper discusses children in the online space who are entrapped in interactions across various social media applications and digital platforms and became victims of sexual exploitation practices and how this sexual exploitation is facilitated by the availability of diverse financial service providers that allow for transactions between perpetrators and victims as well as distributors and producers. In view of ongoing efforts by the Indonesian government to formulate more relevant and effective regulations for child protection, this study is crucial for our understanding of the realities of sexual exploitation in the context of children’s use of social media and may …

Ambient Artificial Intelligence In Health Care Documentation: A Review Of Tools, Integration, And Clinical Implications, Jasmin Hundal, Molly Jain Md, Joseph Mccollom Do

PCI Publications and Projects

Introduction: Ambient artificial intelligence (AAI) is increasingly being integrated into clinical workflows to address the documentation burden contributing to clinician burnout. AAI systems use automatic speech recognition and natural language processing to capture real-time clinician–patient dialogue and generate structured documentation within the electronic health record. Methods: This review examines AAI’s technical foundations, clinical applications, and implementation considerations in oncology practice. We describe how current AAI tools extract, classify, and populate relevant clinical content, such as the history of present illness, physical examination findings, and assessment and plan, while adhering to established US coding standards (e.g., International Classification of Diseases [ICD-10]). …

College Of Nursing Apr 2024 Self-Study Report, Unm Academic Program Review

UNM Academic Program Review

College of Nursing complete an annual academic program review and included in the self-study report for AY2024

Beyond The Call Of Duty: Exploring The Prevalence And Consequences Of Self-Sacrifice By Academic Library Leaders, Kate Tallman, Susan R. Franzen

Faculty and Staff Publications – Milner Library

In the face of limited resources and increasing demand, academic library supervisors often  sacrifice their own time and energy to support employees’ well-being. Self-sacrificial  behavior includes taking on additional responsibilities, being especially “visible” during  crises, and supporting the emotional, physical, or financial needs of employees. Most research on self-sacrificial leadership highlights its positive impact on organizational  culture. But how does it impact library leaders’ mental health, job satisfaction, and/or  attrition? This presentation explores self-sacrificial behavior and concludes with a  discussion of strategies to reset the balance when leaders find themselves going above  and beyond at their own expense.

Nothing To Report: Moral And Pedagogical Reflections From A Voyage Into Engineering Curricula For Sustainable Development Goals, Brad Tabas, Una Beagon, Klara Kovesi

Research Outputs: 2025-Present

This essay chronicles the intellectual voyage of an ordinary language philosopher within a European Union-funded project (A-STEP 2030) using quantitative social science methods to define sustainability competencies for engineering education. Thinking through the standard ‘lit review’ and expert-validation procedures, it explores the philosophical and pedagogical perplexities emergent from arrogating a right to claim to know how to educate coming generations in order to achieve the Sustainable Development Goals. Drawing on thinkers like Cavell, Wittgenstein, Emerson, and Thoreau, it raises sceptical questions regarding the ways in which our intellectual tools may limit our capacity to shape a future different from our …

A Spanish-Language Adaptation Of The Brief Wisconsin Inventory Of Smoking Dependence Motives Among Mexican And Mexican-American Adults Who Smoke, Yessenia Castro, Jose E. Velasquez, Zully C. Guerra, Tatiana Londoño, John R. Moore, Nazanin M. Heydarian

School of Social Work Faculty Publications

Introduction: The smoking pattern of Latino smokers differs from non-Latino white smokers such that physical dependence may not be a strong motivator for smoking among Latinos. Multidimensional measures of dependence may be more useful, but there is a lack of psychometrically sound multidimensional Spanish-language measures. This study evaluated the psychometric properties of a Spanish-language adaptation of the Brief Wisconsin Inventory of Dependence Motives (Brief WISDM) for use among Spanish-speaking Latino smokers in the U.S.

Methods: 287 Spanish-speaking Mexican-origin smokers in the U.S. responded to a revised set of Spanish Brief WISDM items. Confirmatory factor analyses and model trimming procedures were …

Lindenwood University Employment Policies, 2025-2026, Lindenwood University

Employee Handbooks

In 2021-2022, Lindenwood University made the Employee Guidebook, online only. This is a compilation of the documents from all of the links in the 2025-2026 Employee Policies site.