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Faxes, Emails, And Cad: A Case Study Of The Changing Landscape In Born-Digital Design Records, 1994-2006, Julia D. Larson Nov 2025

Faxes, Emails, And Cad: A Case Study Of The Changing Landscape In Born-Digital Design Records, 1994-2006, Julia D. Larson

Journal of Western Archives

The article examines the technological changeover from analog to born digital design records in the mid-1990s, and is a case study in how one San Francisco Bay Area landscape architecture firm navigated the paradigm shift. The firm retained extensive documentation of the project management/construction administration for large scale projects, and this case study shows how archivists can utilize the analog documentation (like faxes and printed emails) to gain a greater understanding of how design firms began using Computer Aided Drafting and how CAD changed design and the process of archiving.

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Does Employees’ Meaningfulness Of Work Mediate The Link Between Their Cognitive Diversity And Creative Process Engagement?, Mohammad Tamzid Hossain, Sabrin Sultana, Salma Begum, Md. Sahidur Rahman, Md. Aftab Uddin Nov 2025

Does Employees’ Meaningfulness Of Work Mediate The Link Between Their Cognitive Diversity And Creative Process Engagement?, Mohammad Tamzid Hossain, Sabrin Sultana, Salma Begum, Md. Sahidur Rahman, Md. Aftab Uddin

Management Dynamics

This study aims to investigate how employees' cognitive diversity affects their creative process engagement, with a focus on the role of their meaningfulness of work as a mediator in this connection. A survey was used with a quantitative method to collect responses from 207 employees of small, medium, and large service and manufacturing businesses in Bangladesh that were registered with the Chittagong Chamber of Commerce and Industry. The collected data were then analyzed using Smart PLS 4 to evaluate the hypotheses and examine the mediating effect of the study. The findings reveal that employees’ cognitive diversity has a significant impact …

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Accountability And Enforcement Aspects Of The Eu General Data Protection Regulation – Methodology For The Creation Of An Effective Compliance Framework And A Review Of Recent Case Law, Paolo Balboni, Martim Taborda Barata, Anastasia Botsi, Kate Francis Nov 2025

Accountability And Enforcement Aspects Of The Eu General Data Protection Regulation – Methodology For The Creation Of An Effective Compliance Framework And A Review Of Recent Case Law, Paolo Balboni, Martim Taborda Barata, Anastasia Botsi, Kate Francis

Indian Journal of Law and Technology

The General Data Protection Regulation (GDPR), which has been applicable within the EU/EEA since 18 May 2018, has brought about reinforced rules on personal data protection which have dramatically shifted the paradigm for all organisations bound by them. This includes not just those which actively handle personal data as a core part of their business model, but also those which are required to handle personal data (on employees, customers or suppliers, for example) as part of their day-to-day activities – in other words, all organisations falling under the GDPR’s scope. By holding organisations responsibile for their own compliance, and requiring …

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The Weight Of Secrets: Assessing The Regulatory Burden For Informational Privacy In India, Lalit Panda Nov 2025

The Weight Of Secrets: Assessing The Regulatory Burden For Informational Privacy In India, Lalit Panda

Indian Journal of Law and Technology

Given the galloping pace at which information technology continues to develop and penetrate our lives, it is inevitable that the aspirations of data protection will sometimes appear like hollow promises that the law cannot keep. This makes it essential to study the precise regulatory conditions that can allow for the effective enforcement of legal protections for informational privacy. This Article provides a holistic account of the likely breadth and regulatory burden of an effective data protection regime and attempts to flesh out various regulatory tools that can go into the design of a Data Protection Authority for India so as …

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Law Enforcement Access To Data In India: Considering The Past, Present, And Future Of Section 91 Of The Code Of Criminal Procedure, 1973, Tarun Krishnakumar Nov 2025

Law Enforcement Access To Data In India: Considering The Past, Present, And Future Of Section 91 Of The Code Of Criminal Procedure, 1973, Tarun Krishnakumar

Indian Journal of Law and Technology

Developments in modern technology and the Internet have resulted in vastly greater quantities of information being stored in electronic form. In addition to gains for convenience, innovation, and the economy, this trend also means that law enforcement and other government agencies are required to increasingly turn to the digital domain to gather evidence for investigative or enforcement purposes. In the Indian context, this usually means having to rely on pre-digital era procedural powers such as Section 91 the Code of Criminal Procedure, 1973. Drawing from existing literature, case law, and developments in policy, this article seeks to conduct an analysis …

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Recombination Suppression Drives Expansion Of The Drosophila Dot Chromosome, Timothy J Stanek, Wilson Leung, Christopher D Shaffer, Ishtar Olaveja, Annabelle Laughlin, Jaquelyn Hester, Darwin Garrido, Emily K Oh, Maria Volski, Nistha Panda, Mia Mo, Ethan Cordes, Martin Dalling, Kacie Kershaw, Malcolm Arnott, Stephen Daly, Silvia Garcia Valenzuela, Paige Thompson, Kayla L Hastert, Destiny Sabb, Kathryn Karpinski, Meher Naaz Arora, Nicholas Rius, Larissa Lobello, Sebastian Jaramillo, Omkar Sonavane, Alice Herrmann, Laura K Reed, Sarah C R Elgin, Cindy Arrigo, Christopher E Ellison Nov 2025

Recombination Suppression Drives Expansion Of The Drosophila Dot Chromosome, Timothy J Stanek, Wilson Leung, Christopher D Shaffer, Ishtar Olaveja, Annabelle Laughlin, Jaquelyn Hester, Darwin Garrido, Emily K Oh, Maria Volski, Nistha Panda, Mia Mo, Ethan Cordes, Martin Dalling, Kacie Kershaw, Malcolm Arnott, Stephen Daly, Silvia Garcia Valenzuela, Paige Thompson, Kayla L Hastert, Destiny Sabb, Kathryn Karpinski, Meher Naaz Arora, Nicholas Rius, Larissa Lobello, Sebastian Jaramillo, Omkar Sonavane, Alice Herrmann, Laura K Reed, Sarah C R Elgin, Cindy Arrigo, Christopher E Ellison

Faculty, Staff and Student Publications

Genome size varies widely, even among closely related species, yet much less is known about chromosome size variation. Here we use the fourth chromosome of Drosophila, also known as the "Muller F element" or "dot chromosome", as a model to investigate chromosome-specific size expansion. The F element of most Drosophila species is small (∼1.3 Mb) and almost entirely heterochromatic, yet harbors approximately 80 protein-coding genes. Here, we study D. kikkawai, D. takahashii, D. ananassae, and D. bipectinata, whose F elements are 2- to 15-fold larger in size compared to D. melanogaster. Through manual gene curation and comparative genomic analysis, we …

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From Digital Divide To Equity-Enhancing Diffusion: Generative Ai And Writing Quality, Rebecca Tukachinsky Forster, Kerk Kee, Gabriel Miao Li Nov 2025

From Digital Divide To Equity-Enhancing Diffusion: Generative Ai And Writing Quality, Rebecca Tukachinsky Forster, Kerk Kee, Gabriel Miao Li

Communication Faculty Articles and Research

This study investigates whether generative AI can narrow the gap between stronger and developing writers and explores the mechanisms underlying these effects. In a within-subject experiment, students wrote two essays, with and without AI assistance. Computer-aided analysis of the writing quality confirmed that while all students benefited from AI, that less skillful writers gained more. There was also no evidence of skillful writers using AI in more sophisticated and beneficial ways. The study contributes to theorizing the digital divide and offers insights into maximizing the benefits of AI tools. Theoretically, we situate generative-AI use within Diffusion of Innovations, treating ChatGPT …

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Fusion Of Simulation And Ai Methods For Understanding Hov/Hot Lane Operational Flow Dynamics, Deo Chimba, Therezia Matongo, Hellen Shita, Erickson Senkondo, Masanja Madalo, Afia Yeboah Nov 2025

Fusion Of Simulation And Ai Methods For Understanding Hov/Hot Lane Operational Flow Dynamics, Deo Chimba, Therezia Matongo, Hellen Shita, Erickson Senkondo, Masanja Madalo, Afia Yeboah

Civil and Architectural Engineering Faculty Research

This study investigated the impact of converting High Occupancy Vehicle (HOV) lanes to High Occupancy Toll (HOT) lanes on fundamental traffic flow characteristics, focusing on speed, density, and flow relationships. A 25-mile HOV corridor along I-24 Westbound in Nashville, Tennessee was evaluated using both microscopic simulation via VISSIM and data-driven machine learning through a Multi-Layer Perceptron (MLP) neural network. Four operational scenarios were assessed: (1) HOV lanes without enforcement, (2) HOV lanes with effective occupancy enforcement, (3) HOT lanes with limited access points, and (4) HOT lanes with intermediate access points. Flow-density and speed-flow relationships were modeled using Greenshields theory …

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The Tamads2-Tatbl21 Module Enhances Wheat Resistance To Stripe Rust By Activating Tagkl-Mediated Immunity, Shijia Zhao, Hao Chu, Yanan Lu, Jiaqi Chen, Xu Wang, Guangxiang Tian, Mingjing Zhang, Pengyu Song, Yanhui Zhang, Guihua Bai, Gangming Zhan, Zhensheng Kang, Wenming Zheng, Zhengqing Fu, Na Liu Nov 2025

The Tamads2-Tatbl21 Module Enhances Wheat Resistance To Stripe Rust By Activating Tagkl-Mediated Immunity, Shijia Zhao, Hao Chu, Yanan Lu, Jiaqi Chen, Xu Wang, Guangxiang Tian, Mingjing Zhang, Pengyu Song, Yanhui Zhang, Guihua Bai, Gangming Zhan, Zhensheng Kang, Wenming Zheng, Zhengqing Fu, Na Liu

Faculty Publications

Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) poses a catastrophic threat to global food security. While MADS-box transcription factors regulate development and abiotic stress, their roles in plant-pathogen immunity remain enigmatic. In this study, we identified TaMADS2, a Pst-induced MADS-box gene, as a positive regulator of wheat resistance. Functional analyses demonstrated that TaMADS2 overexpression significantly enhanced Pst resistance, whereas its knockdown rendered wheat more susceptible. Further investigation revealed that TaMADS2 interacts with trichome birefringence-like protein 21 (TaTBL21) to activate glycerol kinase-like (TaGKL) expression. Silencing TaGKL in wild-type or TaMADS2-overexpressing lines …

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Benchmarking Dna Foundation Models For Genomic And Genetic Tasks, Haonan Feng, Lang Wu, Bingxin Zhao, Chad Huff, Jianjun Zhang, Jia Wu, Lifeng Lin, Peng Wei, Chong Wu Nov 2025

Benchmarking Dna Foundation Models For Genomic And Genetic Tasks, Haonan Feng, Lang Wu, Bingxin Zhao, Chad Huff, Jianjun Zhang, Jia Wu, Lifeng Lin, Peng Wei, Chong Wu

School of Medicine Faculty Publications

The rapid evolution of DNA foundation models promises to revolutionize genomics, yet comprehensive evaluations are lacking. Here, we present a comprehensive, unbiased benchmark of five models (DNABERT-2, Nucleotide Transformer V2, HyenaDNA, Caduceus-Ph, and GROVER) across diverse genomic and genetic tasks including sequence classification, gene expression prediction, variant effect quantification, and topologically associating domain (TAD) region recognition, using zero-shot embeddings. Our analysis reveals that mean token embedding consistently and significantly improves sequence classification performance, outperforming other pooling strategies. Model performance varies among tasks and datasets; while general purpose DNA foundation models showed competitive performance in pathogenic variant identification, they were less …

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Quality Improvement Project: The Impact Of Staff Education On Utilization Of The Phq-9 Tool And Follow-Up Management Protocol, Shuntak Jerideau Nov 2025

Quality Improvement Project: The Impact Of Staff Education On Utilization Of The Phq-9 Tool And Follow-Up Management Protocol, Shuntak Jerideau

Doctor of Nursing Practice Projects

Depression is a prevalent mental health disorder that affects daily functioning. Timely screening enables the identification of symptoms, monitoring treatment efficacy, and informs additional treatment such as referrals. The practice site reported low screening rates of patient’s post-psychiatric hospitalization, which was attributed to inadequate knowledge of the PHQ-9 tool. The purpose of this quality improvement project was to evaluate the impact of staff education on the utilization of the PHQ-9 tool and follow-up management protocol in a mental health clinic. A quasi-experimental design method was used in an outpatient mental health clinic. Pretest knowledge of the PHQ-9 was obtained from …

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Assessing The Impact Of Cultural Competence Training For Providers Serving Native Americans, Chinazo Obi Nov 2025

Assessing The Impact Of Cultural Competence Training For Providers Serving Native Americans, Chinazo Obi

Doctor of Nursing Practice Projects

The United States is a culturally diverse nation, yet many healthcare providers report challenges in delivering care that respects cultural values and traditions. Within mental health settings, this gap is especially concerning for Native American populations, who experience disproportionately high rates of mental health conditions and face barriers to culturally responsive care. The purpose of this quality improvement project was to assess the impact of a cultural competence education and training intervention on mental health providers’ knowledge and self-efficacy in delivering culturally competent care to Native American patients. Guided by Leininger’s Culture Care Theory of Diversity and Universality and the …

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Retrieval Augmented Framework For Deepfake Audio Detection, Avinash Saxena Nov 2025

Retrieval Augmented Framework For Deepfake Audio Detection, Avinash Saxena

Master's Theses

The widespread use of AI-based audio deepfakes threatens severely to undermine media integrity and public trust. Speech synthesis techniques have improved dramatically in voice conversion (VC) and text-to-speech (TTS) in recent years, making forgeries sound highly realistic, and concerns are raised about possible malevolent uses. Existing state-of-the-art techniques for identifying fake speech have proven to be effective in some cases but are still limited in application and robustness when faced with novel attacking strategies, different acoustic conditions, or alternative linguistic domains. To address some of these limitations, the current research presents a novel deepfake audio detection system based on personalized …

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The Intersection Of Near-Death Experiences (Ndes) And Traumatic Brain Injury (Tbi): Neurobiological, Phenomenological, And Creative Implications, Diego Iacono, Gloria C Feltis Nov 2025

The Intersection Of Near-Death Experiences (Ndes) And Traumatic Brain Injury (Tbi): Neurobiological, Phenomenological, And Creative Implications, Diego Iacono, Gloria C Feltis

Department of Neurology Faculty Papers

Traumatic brain injury (TBI) and near-death experiences (NDEs) represent profound disruptions in brain function, often associated with dramatic changes in consciousness, self-perception, and behavior. While these events are typically studied for their pathological consequences, a growing body of evidence suggests they may also trigger unexpected cognitive and creative enhancements in a subset of individuals. We explore the intersection between TBI, NDEs, and the emergence of heightened artistic expression, integrating findings from neuroanatomy, neuropathology, genetics, and phenomenology. We examine how alterations in key brain networks - such as the default mode network, frontoparietal circuits, and limbic regions - may underpin shifts …

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Development Of A Digestion Procedure Using Fe2+ Ions For Electrochemical Detection Of Mno2 Particles In Drinking Water, Kayla Elliott, Sarah Jane Payne, Zhe She Nov 2025

Development Of A Digestion Procedure Using Fe2+ Ions For Electrochemical Detection Of Mno2 Particles In Drinking Water, Kayla Elliott, Sarah Jane Payne, Zhe She

Journal of Electrochemistry

Developing methods for detection contaminants in drinking water is essential to ensuring that safe and acceptable quality drinking water is delivered to consumers. While manganese (Mn) was previously known only as a mere aesthetic issue, recent epidemiological data has shown to have negative neurological effects on humans, especially on children, prompting new health-based guidelines by Health Canada and the World Health Organization. In drinking water, Mn exists predominantly as Mn(II) and Mn(IV), and is regulated based on total Mn levels. Interestingly, measurement of Mn particulate using electroanalytical methods has not yet been reported in the literature. Herein, a digestion procedure …

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Gender Differences In Healthy Eating Index As Informed By The Awareness Of Diagnosis Of Metabolic Dysfunction-Associated Steatotic Liver Disease, Wei Ting Lin, Madeline Novack, Suthat Liangpunsakul, Chiung Kuei Huang, Hui Yi Lin, Po Hung Chen, Tung Sung Tseng, Peng Sheng Ting Nov 2025

Gender Differences In Healthy Eating Index As Informed By The Awareness Of Diagnosis Of Metabolic Dysfunction-Associated Steatotic Liver Disease, Wei Ting Lin, Madeline Novack, Suthat Liangpunsakul, Chiung Kuei Huang, Hui Yi Lin, Po Hung Chen, Tung Sung Tseng, Peng Sheng Ting

School of Public Health Faculty Publications

Background/Objectives: Dietary quality is a driver of metabolic dysfunction-associated steatotic liver disease (MASLD). Men and women often have different levels of adherence to medical advice, but the effect of gender on adherence to dietary advice as a function of awareness of MASLD is understudied. We aim to investigate the differences in diet quality between men and women who are aware of their diagnosis of MASLD compared to their undiagnosed counterparts. Methods: We utilized the National Health and Nutrition Examination Survey 2017–2020 to identify a nationally representative sample of subjects with MASLD, 127 of whom reported a diagnosis of MASLD (diagnosed …

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Low Magnetic Fields Stimulate Cardiac Mitochondrial Bioenergetics With A Bell-Shaped Response: Possibly Via A Radical Pair Mechanism, Gisela Beutner, Huoy-Jen Yuh, Ilan Goldenberg, Douglas C. Wallace, George A. Porter, Arthur J. Moss, Shey-Shing Sheu Nov 2025

Low Magnetic Fields Stimulate Cardiac Mitochondrial Bioenergetics With A Bell-Shaped Response: Possibly Via A Radical Pair Mechanism, Gisela Beutner, Huoy-Jen Yuh, Ilan Goldenberg, Douglas C. Wallace, George A. Porter, Arthur J. Moss, Shey-Shing Sheu

Center for Translational Medicine Faculty Papers

Low magnetic fields (LMFs) of less than 1 × 10 3 Tesla (T) affect numerous biological processes, including plant growth and bird migration. At a cellular level, LMFs influence intracellular Ca2+ concentrations and generation of mitochondrial reactive oxygen species (mROS). However, the mechanisms that account for these effects are controversial. Here, by applying a static LMF, ranging from ~2.7 × 10 4 to ~1.9 × 10 3 T, to mitochondria isolated from adult rat hearts, a bell-shaped increase in State 3 respiration (S3R) was observed, up to 40 %. A similar LMF-induced increase in S3R was also observed in mitochondria …

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High Variability In Flood Discharge And Stage Accelerates River Mobility, Chenliang Wu, Wonsuck Kim, Shuo Yang, Frank Tsai, Jeffrey A. Nittrouer, Tian Y. Dong, Duhwan Keum, Kyle M. Straub Nov 2025

High Variability In Flood Discharge And Stage Accelerates River Mobility, Chenliang Wu, Wonsuck Kim, Shuo Yang, Frank Tsai, Jeffrey A. Nittrouer, Tian Y. Dong, Duhwan Keum, Kyle M. Straub

School of Earth, Environmental, & Marine Sciences Faculty Publications

Lateral channel migration is a fundamental process in natural alluvial rivers; however, the factors that control the rate of migration remain unclear. Despite its importance in shaping river morphology, the impact of water discharge on river mobility is still largely unexplored. Here, we leverage a dataset of 64 rivers across the globe to show that higher variability in river discharge and stage promotes higher rates of river migration. To reveal the physical processes behind this relationship, we focused analyses on the lowermost 500 kilometers of the Mississippi River, where a pronounced gradient in water stage variability and migration rate exists. …

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Workplace Policy And Associated Factors Of Minimum Acceptable Diet Practices: An Online Survey Among Working Mothers In Indonesia, Fadhila Iswi Deandra, Judhiastuty Februhartanty, Muchtaruddin Mansyur Nov 2025

Workplace Policy And Associated Factors Of Minimum Acceptable Diet Practices: An Online Survey Among Working Mothers In Indonesia, Fadhila Iswi Deandra, Judhiastuty Februhartanty, Muchtaruddin Mansyur

Kesmas

Working mothers in Indonesia may influence complementary feeding practices, particularly their ability to ensure that their infants properly meet the minimum acceptable diet (MAD). In this cross-sectional study, an online survey was distributed through various online platforms where participants were recruited using convenience sampling. The questionnaire covered sociodemographic factors, workplace policies, and infant and young child feeding (IYCF) practices. Descriptive and logistic regression analyses were conducted. A total of 394 working mothers participated, of which over 90% of the respondents reported meeting minimum dietary diversity, minimum milk frequency, minimum milk feeding frequency, and MAD indicators as assessed with a standardized …

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Burnout Assessment Tool Development And Validation For Healthcare Workers: A Psychometric Approach Using Rasch Modelling And Exploratory Factor Analysis, Rosnah Ismail, Suriya Kumareswaran Vallasamy Nov 2025

Burnout Assessment Tool Development And Validation For Healthcare Workers: A Psychometric Approach Using Rasch Modelling And Exploratory Factor Analysis, Rosnah Ismail, Suriya Kumareswaran Vallasamy

Kesmas

Burnout remains a significant occupational threat to healthcare workers (HCWs). Existing instruments, e.g., the Maslach Burnout Inventory, have limited applicability in healthcare-specific contexts. This study aimed to develop and validate the Burnout Scale for Assessing Stress in Healthcare Workers (BSAS-HCW), designed to measure cognitive and emotional exhaustion. A cross-sectional survey was conducted among 245 Malaysian HCWs representing diverse roles, including staff nurses (57.7%), house officers (14.3%), medical officers (13.5%), specialists (5.7%), pharmacists (4.5%), and other HCWs. Exploratory factor analysis revealed a two-factor structure with strong internal consistency (Cronbach's alpha: cognitive = 0.95; emotional = 0.97), and all items loaded above …

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Analysis Of Public Knowledge, Attitudes, And Practices In Food And Drug Selection In Indonesia, Tina Wikara, Sri Astuti, Sri Nurhayati, Rotua Uli Carolina, Evi Ratna Sari Nov 2025

Analysis Of Public Knowledge, Attitudes, And Practices In Food And Drug Selection In Indonesia, Tina Wikara, Sri Astuti, Sri Nurhayati, Rotua Uli Carolina, Evi Ratna Sari

Kesmas

As consumers, the public plays a vital role in ensuring the safe and appropriate use of products. This study aimed to assess awareness of food and drug safety and quality among the Indonesian population. Using a cross-sectional survey, the authors measured public awareness across three key dimensions: knowledge, attitudes, and practices. Data were collected from 20,610 respondents aged 17–65 years from 34 provinces in Indonesia. The survey approach employed a three-stage stratified sampling design. Data were collected through structured face-to-face interviews, and the results were presented as an index ranging from 0 to 100 (low to high awareness). The respondents …

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Improving Glycemic Control Among Indonesian Urban Adults: A Digital And Behavioral Extension Of The Information–Motivation–Behavioral Skills Model, Imelda Appulembang Nov 2025

Improving Glycemic Control Among Indonesian Urban Adults: A Digital And Behavioral Extension Of The Information–Motivation–Behavioral Skills Model, Imelda Appulembang

Kesmas

Management of type 2 diabetes mellitus (T2DM) in Indonesia continues to face challenges due to behavioral, informational, and technological gaps among patients. This study analyzed the influence of self-regulatory competence and information, motivation, family support, and digital health literacy on glycemic control behavior. A cross-sectional survey was conducted from February to April 2025 among 587 adults aged >30 years with T2DM enrolled in the Chronic Disease Management Program at primary health care in six major cities: Jakarta, Surabaya, Yogyakarta, Medan, Makassar, and Banjarmasin. Data were collected through structured questionnaires and analyzed using partial least squares structural equation modeling. The findings …

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Regulating Lithium Metal Nucleation And Growth For Dendrite Suppression: From Liquid-Electrolyte To Solid-State Batteries, Ao Du, Juan Zhang, Pan Xu, Ya-Jie Li, Kang-Yu Yi, Zhen-Zhen Shen, Hui-Lin Ge, Guang-Wen Zhang, Chao-Hui Zhang, Yu-Hao Wang, Chen-Zi Zhao, Meng-Yang Xu, Yu-Lin Jie, Rui Wen, Shu-Hong Jiao, Si-Qi Shi, Qiang Zhang, Chun-Peng Yang, Yu-Guo Guo Nov 2025

Regulating Lithium Metal Nucleation And Growth For Dendrite Suppression: From Liquid-Electrolyte To Solid-State Batteries, Ao Du, Juan Zhang, Pan Xu, Ya-Jie Li, Kang-Yu Yi, Zhen-Zhen Shen, Hui-Lin Ge, Guang-Wen Zhang, Chao-Hui Zhang, Yu-Hao Wang, Chen-Zi Zhao, Meng-Yang Xu, Yu-Lin Jie, Rui Wen, Shu-Hong Jiao, Si-Qi Shi, Qiang Zhang, Chun-Peng Yang, Yu-Guo Guo

Journal of Electrochemistry

Lithium metal anodes, with a theoretical capacity of up to 3860 mAh·g−1, are regarded as the cornerstone for developing next-generation high-energy-density batteries. However, several key challenges hinder their practical applications, including dendrite formation, unstable solid electrolyte interphase (SEI), side reactions with electrolytes, and associated safety risks. This review systematically explores the mechanisms of lithium nucleation, growth, and stripping in both liquid and solid-state battery systems, analyzing critical theoretical concepts like heterogeneous nucleation thermodynamics, surface diffusion kinetics, space charge effects, and SEI-induced nucleation, which are crucial for understanding the genesis of dendrite growth. Additionally, the review discusses the electrochemical-mechanical …

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The Impact Of Extramedullary And Paraskeletal Plasmacytomas On Treatment Outcomes In Multiple Myeloma Treated With Teclistamab: U.S. Myeloma Immunotherapy Consortium Real-World Experience, Aimaz Afrough, Danai Dima, Beatrice Razzo, Utkarsh Goel, Aishwarya Sannareddy, Oren Pasvolsky, Mariola Vazquez-Martinez, Christopher Ferreri, Rahul Banerjee, Jack Khouri, James Davis, Mahmoud Gaballa, Alex Lieberman-Cribbin, Masooma Rana, Kelley Julian, Faiz Anwer, Leyla Shune, Shaun Dejarnette, Ariel Grajales-Cruz, Evguenia Ouchveridze, Gabriel De Avila, Sandra Susanibar-Adaniya, Andrew Portuguese, Daniel Schrum, Erin Eberwein, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Joseph Mcguirk, Adriana Rossi, Megan Herr, Omar Castaneda, Frederick Locke, Shahzad Raza, Yi Lin, Shebli Atrash, Douglas Sborov, Peter Voorhees, Shambavi Richard, Alfred Garfall, Surbhi Sidana, Krina Patel, Doris Hansen, Andrew Cowan, Larry Anderson, Hans Lee Nov 2025

The Impact Of Extramedullary And Paraskeletal Plasmacytomas On Treatment Outcomes In Multiple Myeloma Treated With Teclistamab: U.S. Myeloma Immunotherapy Consortium Real-World Experience, Aimaz Afrough, Danai Dima, Beatrice Razzo, Utkarsh Goel, Aishwarya Sannareddy, Oren Pasvolsky, Mariola Vazquez-Martinez, Christopher Ferreri, Rahul Banerjee, Jack Khouri, James Davis, Mahmoud Gaballa, Alex Lieberman-Cribbin, Masooma Rana, Kelley Julian, Faiz Anwer, Leyla Shune, Shaun Dejarnette, Ariel Grajales-Cruz, Evguenia Ouchveridze, Gabriel De Avila, Sandra Susanibar-Adaniya, Andrew Portuguese, Daniel Schrum, Erin Eberwein, Hitomi Hosoya, Lekha Mikkilineni, Gurbakhash Kaur, Joseph Mcguirk, Adriana Rossi, Megan Herr, Omar Castaneda, Frederick Locke, Shahzad Raza, Yi Lin, Shebli Atrash, Douglas Sborov, Peter Voorhees, Shambavi Richard, Alfred Garfall, Surbhi Sidana, Krina Patel, Doris Hansen, Andrew Cowan, Larry Anderson, Hans Lee

Department of Medical Oncology Faculty Papers

Teclistamab, a bispecific antibody targeting B-cell maturation antigen (BCMA), is effective in relapsed or refractory multiple myeloma (RRMM), but its impact on patients with soft tissue plasmacytomas is unclear. We studied 385 RRMM patients treated with teclistamab at 13 U.S. centers through September 2023, with follow-up to April 2024. Soft tissue plasmacytomas were classified as true extramedullary disease (EMD; not contiguous with bone) or paraskeletal plasmacytomas (PSK; contiguous with bone). Patients with the simultaneous presence of both were classified as true-EMD, reflecting its adverse prognosis. Of those, 109 (28%) had true EMD, 33 (9%) had PSK, and 243 (63%) had …

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Fluorosilane-Induced Softening And Collapse Of Micropillar Arrays, Gabriela Moreira Lana, Maja Fehlberg, Petra Herbeck-Engel, Gisela Heppe, Raimund Schlüßler, Torsten Jähnke, Eduard Arzt, Roland Bennewitz Nov 2025

Fluorosilane-Induced Softening And Collapse Of Micropillar Arrays, Gabriela Moreira Lana, Maja Fehlberg, Petra Herbeck-Engel, Gisela Heppe, Raimund Schlüßler, Torsten Jähnke, Eduard Arzt, Roland Bennewitz

Chemical and Biochemical Engineering Faculty Research & Creative Works

Replica molding is a widely used technique for the fabrication of polymer microstructures. As structural dimensions decrease, anti-stick surface treatment of the mold becomes increasingly critical to ensure clean demolding and preserve structural integrity. We fabricated arrays of micropillars with 20 µm diameter and 60 µm height using medical-grade polydimethylsiloxane (PDMS), MDX4-4210, and observed a high fraction of collapsed pillars for the first molding after fluorosilanization of the mold to reduce sticking. To address this issue, we systematically investigated the surface treatment protocol for the molds, made from the PDMS Sylgard 184. We provide results from complementary measurement methods, to …

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Biocompatible And Antibacterial Pcl-Tio2@Ag/Γ-Cd Mof Nanocomposite Coating For Corrosion Resistance Of Magnesium Alloy In Simulated Body Fluid, Sara Dehghan-Chenar, Hamid R. Zare, Zahra Mohammadpour, Maryam Sadat Mirbagheri-Firoozabad Nov 2025

Biocompatible And Antibacterial Pcl-Tio2@Ag/Γ-Cd Mof Nanocomposite Coating For Corrosion Resistance Of Magnesium Alloy In Simulated Body Fluid, Sara Dehghan-Chenar, Hamid R. Zare, Zahra Mohammadpour, Maryam Sadat Mirbagheri-Firoozabad

Journal of Electrochemistry

Magnesium alloys are promising candidates for bio-implant applications due to their biodegradability and biocompatibility. However, their rapid corrosion remains a critical limitation. This study presents the development of a multifunctional nanocomposite coating designed to enhance the corrosion resistance and antibacterial properties of magnesium alloy implants. The coating comprised γ-cyclodextrin metal-organic frameworks (γ-CD MOFs) decorated with TiO2@Ag core-shell nanoparticles, embedded in a polycaprolactone (PCL) matrix. Immersion tests in a simulated body fluid (SBF) revealed an initially higher corrosion rate for the PCL-TiO2@Ag/γ-CD MOF coating compared to the coating without TiO2@Ag nanoparticles; however, it demonstrated significant …

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Ai-Based Mapping Of Offshore Wind Energy Around The Korean Peninsula Using Sentinel-1 Sar And Numerical Weather Prediction Data, Jason Sung-Uk Joh, Son V. Nghiem, Menas Kafatos, Jay Liu, Jinsoo Kim, Seung Hee Kim Nov 2025

Ai-Based Mapping Of Offshore Wind Energy Around The Korean Peninsula Using Sentinel-1 Sar And Numerical Weather Prediction Data, Jason Sung-Uk Joh, Son V. Nghiem, Menas Kafatos, Jay Liu, Jinsoo Kim, Seung Hee Kim

Institute for ECHO Articles and Research

Offshore wind farm projects are being promoted in the seas surrounding the Korean Peninsula to secure renewable energy. To support site selection, offshore wind resource maps were generated using deep neural networks trained on Sentinel-1 SAR imagery, numerical weather prediction data, offshore wind observations, sea surface temperature, and bathymetry. The deep neural network (DNN) framework consisted of six sub-models targeting eastward and northward wind components across three regions—the Yellow Sea, Korea Strait, and East Sea—to account for spatial heterogeneity. The proposed models outperformed existing approaches, achieving mean absolute errors (MAE) ranging from 1.31 to 1.69 m/s and correlation coefficients (CC) …

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Mecp2 Interacts With The Super Elongation Complex To Regulate Transcription, Jun Young Sonn, Wonho Kim, Marta Iwanaszko, Yuki Aoi, Yan Li, Guantong Qi, Luke Parkitny, Janice L Brissette, Lorin Weiner, Juan Botas, Ismael Al-Ramahi, Ali Shilatifard, Huda Y Zoghbi Nov 2025

Mecp2 Interacts With The Super Elongation Complex To Regulate Transcription, Jun Young Sonn, Wonho Kim, Marta Iwanaszko, Yuki Aoi, Yan Li, Guantong Qi, Luke Parkitny, Janice L Brissette, Lorin Weiner, Juan Botas, Ismael Al-Ramahi, Ali Shilatifard, Huda Y Zoghbi

Faculty, Staff and Students Publications

Loss-of-function mutations in methyl-CpG binding protein 2 (MECP2) cause Rett syndrome. While we know that MeCP2 binds to methylated cytosines on DNA, the full breadth of the molecular mechanisms by which MeCP2 regulates gene expression remains incompletely understood. Here, using a genetic modifier screen, we identify the super elongation complex, a P-TEFb–containing elongation factor that releases promoter-proximally paused RNA polymerase II, as a genetic interactor of MECP2. MeCP2 physically interacts with SEC subunits and directly binds AFF4, the scaffold of the SEC, via the transcriptional repression domain. Furthermore, MeCP2 facilitates the binding of AFF4 on a subset …

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Dose-Dependent Benefits Of Dietary Yeast Cell Wall Supplementation On The Growth Performance And Stress Resilience Of The European Seabass (Dicentrarchus Labrax), Camille Houdelet, Ana Teresa Goncalves, Jorge Dias, Mark Rawling, Eric Leclercq Nov 2025

Dose-Dependent Benefits Of Dietary Yeast Cell Wall Supplementation On The Growth Performance And Stress Resilience Of The European Seabass (Dicentrarchus Labrax), Camille Houdelet, Ana Teresa Goncalves, Jorge Dias, Mark Rawling, Eric Leclercq

School of Biological and Marine Sciences

Preventive health management is central to modern aquaculture practices, within which functional feed additives are a key tool to optimising fish robustness and disease resilience. Despite being well documented, only few studies have assessed the dose–effect of graded levels of S. cerevisiae yeast cell wall (YCW) on fish performance and mucosal barrier immunity. A 9-week trial was conducted to assess the impact of graded levels of YCW on the performance and mucosal barriers of the European seabass under period: (1) non-challenge (43 days) then (2) with an applied husbandry stressors (20 days) in the form of high stocking density, low …

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Risk Exposure And Stakeholder Oversight In College Sports: Lessons From A Lightning Incident, John J. Miller Dr., Jason W. Lee Dr., Elizabeth A. Gregg, Jeffrey F. Levine Nov 2025

Risk Exposure And Stakeholder Oversight In College Sports: Lessons From A Lightning Incident, John J. Miller Dr., Jason W. Lee Dr., Elizabeth A. Gregg, Jeffrey F. Levine

The COSMA Journal

The management of collegiate athletic events increasingly demands systematic approaches to risk identification, assessment, and mitigation, yet risk management education within athletics remains inconsistent. As a result, athletic directors, coaches, and facility managers frequently lack the formal preparation necessary to design and implement effective risk management policies, thereby exposing institutions to operational disruption and legal liability. Severe weather events, particularly lightning storms, underscore the importance of integrating legal principles such as duty of care, premises liability, and foreseeability into institutional planning. This case study, based on a real-life incident, shows that athletic administrators, often with limited formal training in risk …

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