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Road Surface And Subsurface Monitoring Using Machine Learning, Koduah Amoako Dec 2025

Road Surface And Subsurface Monitoring Using Machine Learning, Koduah Amoako

Theses and Dissertations

This thesis presents a comprehensive, non-invasive framework for real-time monitoring of road surface and subgrade conditions using acoustic sensing and machine learning. Traditional Tire-Road Coefficient of Friction (TRCF) estimation techniques often rely on intrusive sensors, offline data analysis, or laboratory measurements, making them impractical for real-time applications. The present research introduces an alternative approach that utilizes the acoustic emissions generated by tire-road interaction to infer both surface friction and subsurface integrity dynamically.Measurement microphones were mounted beneath a test vehicle to record tire-road noise signatures across different pavement textures and vehicle speeds. The collected acoustic signals were processed using Fast Fourier …


Seasonal Performance Of Mrms Qpe In Urban Hydrologic Modeling Using Epa-Swmm, Randall Kirk Bagwell Dec 2025

Seasonal Performance Of Mrms Qpe In Urban Hydrologic Modeling Using Epa-Swmm, Randall Kirk Bagwell

Theses and Dissertations

Accurate rainfall estimation is essential for effective hydrologic modeling, particularly in urban environments where infrastructure must withstand extreme precipitation. This study evaluates the EPA Storm Water Management Model (EPA-SWMM) using MRMS RadarOnly Quantitative Precipitation Estimation (QPE) 1-hour Accumulation as the primary rainfall input for a watershed in Little Rock, Arkansas. The region was selected due to its urban character and the limited availability of radar-based hydrologic studies in Arkansas. 21 storms were analyzed from 2022-2025: 10 in Winter, 7 in Spring, and 4 in Summer. Storms were selected due to their effect on flow. The model was calibrated using February …


Differential Photometric Analysis Of Exoplanet Candidates Toi-1362.01, Toi-2290.01, Toi-6010.01, And Toi-6324.01, Samantha Buck Dec 2025

Differential Photometric Analysis Of Exoplanet Candidates Toi-1362.01, Toi-2290.01, Toi-6010.01, And Toi-6324.01, Samantha Buck

Theses and Dissertations

To maximize the science return from the Transiting Exoplanet Survey Satellite (TESS), the TESS Follow-up Observing Program (TFOP) was created to network scientists and observatories to conduct follow-up observations of potential exoplanets. As members of TFOP-Subgroup 1, we observed four exoplanet candidates: TOI-1362.01, TOI-2290.01, TOI-6010.01, and TOI-6324.01 using the University of North Dakota Space Studies Observatory. The TOI observations were conducted from 31 October 2024 – 15 November, 2024 UTC. AstroImageJ software was used to perform differential photometry and, if a transit event was observed, determine orbital parameters and physical characteristics. Each of the target’s light curves was modeled and …


Control Strategy, Multi-Objective Optimization, And Economic Viability For Utility-Scale Wind-Solar-Based Hybrid Power Plant, Shree Om Bade Dec 2025

Control Strategy, Multi-Objective Optimization, And Economic Viability For Utility-Scale Wind-Solar-Based Hybrid Power Plant, Shree Om Bade

Theses and Dissertations

Hybrid Power Plants (HPP) that combine wind power plants (WPP), solar power plants (SPP), and battery energy storage systems (BESS) have recently emerged to provide dispatchable renewable electricity, improve the stability of the power grid, maximize use of infrastructure assets, and minimize carbon releases. Nevertheless, regardless of their technical potential, the large-scale application of HPP still encounters many barriers, such as operational complexity, inadequate sizing, and financial viability. To mitigate these issues, this study incorporates three research questions. First, this study introduces a four-layer hierarchical control architecture for coordinating WPP, SPP, and BESS to ensure dispatchable power. Second, a multi-objective …


Culture-Dependent Characterization Of Microbial Succession And Persistence In The Integrated Lunar/Martian Analog Habitat (Ilmah), Haley Olivia Boles Dec 2025

Culture-Dependent Characterization Of Microbial Succession And Persistence In The Integrated Lunar/Martian Analog Habitat (Ilmah), Haley Olivia Boles

Theses and Dissertations

This study examines culture-dependent microbial monitoring in a closed lunar/Martian analog habitat, focusing on viable community dynamics relevant to long-duration missions. A standardized sampling and cultivation pipeline was implemented in ILMAH to track microbial succession and persistence under realistic operational conditions. Surface samples were collected across eight habitat zones at five mission timepoints (Days 0, 5, 10, 15, 20) during a 21-day crewed mission. Samples were concentrated post-collection and plated on chromogenic film media to quantify total aerobic bacteria (AC-R), fungi (YM-R), E. coli (EC), and S. aureus (SA). Plates were imaged and enumerated digitally; representative colonies were isolated and …


Spaceflight Safety Regulations: The Case For Implementing Safety Management Systems In The Developing U.S. Commercial Human Spaceflight Industry, Carly Davidson Dec 2025

Spaceflight Safety Regulations: The Case For Implementing Safety Management Systems In The Developing U.S. Commercial Human Spaceflight Industry, Carly Davidson

Theses and Dissertations

Accidents have historically accompanied the development of new transportation systems, often due to technical failures; but human factors – such as organizational culture and management decisions – are increasingly recognized as significant contributors. A strong safety culture, prioritizing safety at all organizational levels, effective management procedures, and open reporting of violations, is believed to improve outcomes by proactively reducing risk in highly technical organizations. These elements form the basis of Safety Management Systems (SMS), which include safety policy, risk management, assurance, and promotion. As commercial spaceflight expands public access to space, US regulators must develop flexible safety regulations that protect …


Thermal Desorption-Pyrolysis Gas Chromatography-Mass Spectrometry Method Development For The Determination Of Wood Preservatives, Nafisa Bala Dec 2025

Thermal Desorption-Pyrolysis Gas Chromatography-Mass Spectrometry Method Development For The Determination Of Wood Preservatives, Nafisa Bala

Theses and Dissertations

A thermal desorption-pyrolysis gas chromatography with mass spectrometric detection (TD-Pyr-GC-MS) method was developed, enabling a comprehensive analysis of preservatives as well as native wood constituents in treated wood. The developed method is based on thermal desorption, i.e., extraction of wood preservatives, followed by pyrolysis to investigate changes in the occurrence of characteristic wood building blocks (e.g., guaiacol derivatives). We implemented a combined MS data acquisition (i.e., SITI) consisting of selected ion monitoring (SIM) and total ion current (TIC), allowing for low limits of detection of preservatives in SIM mode and TIC detection of any evolving species. The matrix detection limits …


The Role Of Attitude Ambivalence In Extending The Theory Of Planned Behavior: A Mixed-Methods Study Of Factors Predicting Influenza Vaccine Uptake Intentions Among Active-Duty Military Parents For Themselves And Their Children, Walter Eugene Carroll Dec 2025

The Role Of Attitude Ambivalence In Extending The Theory Of Planned Behavior: A Mixed-Methods Study Of Factors Predicting Influenza Vaccine Uptake Intentions Among Active-Duty Military Parents For Themselves And Their Children, Walter Eugene Carroll

Theses and Dissertations

This dissertation is a mixed-methods study examining how U.S. military parents form intentions to vaccinate themselves and their children against influenza. The study applies the Theory of Planned Behavior (TPB) and the construct of ambivalence tounderstand how attitudes, social norms, and perceived behavioral control influence vaccination decisions within the unique institutional and cultural environment of military life. Quantitative data were collected from 341 military parents through an online survey distributed across more than 50 military-affiliated Facebook groups. Regression models tested TPB constructs, flu knowledge, and social media use as predictors of vaccination intention and ambivalence. Results showed that flu shot …


The Role Of C-X-C Chemokine Receptor Type 5 (Cxcr5) On Sex-Dependent Neurobehavioral Changes In The Sub Clinically Sensitized Individuals With Repeated Allergen Exposure, Dilini Vimarshani Ekanayake Ekanayake Mudiyanselage Dec 2025

The Role Of C-X-C Chemokine Receptor Type 5 (Cxcr5) On Sex-Dependent Neurobehavioral Changes In The Sub Clinically Sensitized Individuals With Repeated Allergen Exposure, Dilini Vimarshani Ekanayake Ekanayake Mudiyanselage

Theses and Dissertations

Food allergen consumption has been suspected to influence mood and behavior in individuals who are sensitized but tolerant to the food. Using a mouse model of subclinical cow’s milk allergy (CMA), we previously showed that C57BL/6J mice sensitized to β-lactoglobulin (BLG, Bos d 5) exhibited elevated BLG-specific IgE levels even without observable allergic reactions, suggest developing immune responses towards the allergen. We also observed elevated cytokine and chemokine levels, astrogliosis and cortical demyelination along with behavioral changes such as anxiety-like and depression-like behavior after consuming a whey-containing diet for two weeks. Furthermore, we demonstrated the possible immune cell infiltration and …


Resistance Through Policy: Documenting Lgbtq+ Advocacy In Public Education, Rhys Mitchell Fryar Dec 2025

Resistance Through Policy: Documenting Lgbtq+ Advocacy In Public Education, Rhys Mitchell Fryar

Theses and Dissertations

This research examines how educational policies related to LGBTQ+ students are constructed, interpreted, and implemented across federal, state, and district-levels. It asks whether institutional intent reflects authentic commitment to equity or functions as symbolic compliance in politically contested environments. Using Portland Public Schools (PPS) as a case study, the analysis situates the district within Oregon’s affirming policy landscape and the Trump administration’s restrictive federal mandates. PPS has adopted policies, such as Administrative Directive 4.30.061 AD (2023b) and the Gender Identity Support Guide (2023a), to support queer and gender-expansive students; however, it faces a federal investigation (U.S. Department of Education, 2025b, …


Dynamic Wellbore-Integrity Framework For Post-Blowout Capping Of Offshore Wells, Abdelhakim Khouissat Dec 2025

Dynamic Wellbore-Integrity Framework For Post-Blowout Capping Of Offshore Wells, Abdelhakim Khouissat

Theses and Dissertations

In the aftermath of a blowout, a well undergoes a period of unrestricted fluid discharge (de facto primary recovery) followed by pressure buildup after its shut-in, which can adversely impact wellbore integrity. The quintessential example is Union Oil’s 1969 “A-21” well blowout in California’s Santa Barbara Channel, where seafloor-broaching incidents (oil “boilups”) kept taking place from the sides of the well following several failed well-capping attempts, until reservoir depletion eventually allowed a successful shut-in.Analytical and numerical reservoir depletion models are coupled with near-wellbore geomechanics to quantify yardsticks related to the post-blowout discharge utilized to indicate dangers for underground blowouts, in …


Evaluating Hail Spectrometer Data Quality And Uncertainty For Calculating Radar Reflectivity Factor, James Klinman Dec 2025

Evaluating Hail Spectrometer Data Quality And Uncertainty For Calculating Radar Reflectivity Factor, James Klinman

Theses and Dissertations

Reliable in situ measurements are essential for accurately forecasting and nowcasting hailstorms, as they provide insight into storm processes, improve predictions that protect public safety, and help assess potential damage to agriculture and infrastructure. This study evaluates the reliability of in situ hail measurements from the T-28 aircraft’s Hail Spectrometer and assesses their feasibility for radar reflectivity validation and parameterization. Data from 14 flights across five field campaigns were analyzed, focusing on comparisons between one-dimensional (1D) 1-Hz accumulated particle counts and two-dimensional (2D) particle images produced by the Hail Spectrometer. The 2D data were processed using the System for Optical …


False Memory Susceptibility In Association With Attachment Theory: Effects On Memory Conformity, Rachel Catherine Miller Dec 2025

False Memory Susceptibility In Association With Attachment Theory: Effects On Memory Conformity, Rachel Catherine Miller

Theses and Dissertations

False memory research has been an evident topic in various fields of psychological study. Research in this area has important implications in forensic contexts and clinical settings as false memories can result in an array of harmful consequences. To explain individual differences in susceptibility to endorsing false memories of the rare medical procedure known as the voiding cystourethrogram (VCUG), the current study extended the findings of Herndon and colleagues (2014). It also examined predictor variables from attachment theory (such as attachment anxiety and avoidance), depressive symptomatology, compliance levels (e.g., use of confederates), and the impact of guided imagery (i.e., a …


Toward An Anthropological Ecocriticism, Grant Mcmillan Dec 2025

Toward An Anthropological Ecocriticism, Grant Mcmillan

Theses and Dissertations

Environmental storytelling has increasingly reckoned with concepts and assumptions about (N/a)ture inherited from the Western intellectual tradition. The late 2010s and early 2020s in particular have seen an explosion of fiction that interrogates the limits of these past ideas. Relatedly, ecocriticism of this period has entered a self-reflexive mode that has sought to deal with its own limitations while offering insights that may prove generative for a more general audience of environmentally minded readers. This project adds to ongoing ecocritical discourse by tracing a series of implicit affinities between the broad traditions of anthropology and environmental fiction through their shared …


Thermodynamic Evaluation Of The Thermal Methane Pyrolysis Process, Chinaecherem S. Okwuonu Dec 2025

Thermodynamic Evaluation Of The Thermal Methane Pyrolysis Process, Chinaecherem S. Okwuonu

Theses and Dissertations

Natural gas flaring is a persistent challenge which undermines global sustainability and decarbonization efforts as it leads to the waste of valuable energy resources alongside the release of harmful greenhouse gases into the environment. Even when natural gas is utilized through commonly adopted pathways, significant emission of carbon dioxide tends to be realized. Methane pyrolysis offers a promising route in which methane can be decomposed into solid carbon and hydrogen gas with no direct CO2 emissions. However, despite extensive studies of the methane pyrolysis process, a fundamental thermodynamic rationale of the process behavior remains insufficiently explored. This study 1) develops …


Methane Infusion Improved Oil Recovery In The Bakken Formation, Demetrius Maxey Dec 2025

Methane Infusion Improved Oil Recovery In The Bakken Formation, Demetrius Maxey

Theses and Dissertations

This research establishes methane infusion improved oil recovery (MI IOR) as a technically viable and economically attractive early-stage intervention for unconventional reservoirs. Integrated multi-scale investigations included quantum molecular theory, nanoscale characterization, NMR experimentation, and field scale reservoir simulation. FEG-SEM analysis of core samples enabled development of a peer-reviewed pore size classification system informing MI operational design parameters. Integrated well logging quantified petrophysical properties across the Bakken stratigraphy. NMR relaxometry identified the lab-scale pore-level sweep efficiency of MI at 3,750 psi in Bakken core samples. Mobilization of hydrocarbons from Np1, Np2, and Np3 pores yielded recovery factors of 45-60%. Field-scale reservoir …


Identity Formation Through The Lived Experiences Of Immigrant Muslim High School Students, Badera Muhanna Dec 2025

Identity Formation Through The Lived Experiences Of Immigrant Muslim High School Students, Badera Muhanna

Theses and Dissertations

The growing number of Muslim students enrolled in U.S. public schools necessitates a more comprehensive understanding of their unique experiences within their educational environments. This phenomenological qualitative study investigated Muslim students' perceptions of their lived experiences in a high school in the Northern Great Plains of the United States. Six Muslim students in their junior and senior years were selected to participate in semi-structured interviews. Through the lens of Bronfenbrenner’s ecological systems theory, this study aimed to deepen understanding of how Muslim students develop their sense of identity and the factors that contribute to this development. The findings revealed that …


Optimizing Virtual Reality User Experience With Balanced Integration Of Quality Attributes, Ananth Ramaseri Dec 2025

Optimizing Virtual Reality User Experience With Balanced Integration Of Quality Attributes, Ananth Ramaseri

Theses and Dissertations

This dissertation presents a real-time adaptive framework for mitigating cybersickness and enhancing user experience in virtual reality (VR) environments by dynamically adjusting key visual rendering parameters in response to users’ head movements. Conventional VR systems typically rely on fixed or manually configured settings that do not account for individual motion patterns or varying susceptibility to discomfort, leading to suboptimal usability and degraded immersion. In response, this work integrates software architecture tactics with data-driven machine learning models to proactively manage cybersickness while preserving rendering performance.

The proposed system employs a client–server architecture based on the Model-View-Controller (MVC) pattern. We conducted a …


Integrated Machine Learning For Predicting Reservoir Properties And Experimental Approach For Evaluating Co2-Brine-Rock Interactions In Carbonate Formations, Luc Yvan Nkok Dec 2025

Integrated Machine Learning For Predicting Reservoir Properties And Experimental Approach For Evaluating Co2-Brine-Rock Interactions In Carbonate Formations, Luc Yvan Nkok

Theses and Dissertations

Understanding subsurface properties is fundamental for optimizing hydrocarbon recovery and ensuring the long-term integrity of carbon capture and storage (CCS) operations. Conventional methods such as empirical correlations, advanced logging, and laboratory measurements, though widely used, are costly, time-consuming, and often limited in accuracy within formations. This study develops an ML framework to enhance the prediction of petrophysical and geomechanical properties and experimental investigation to evaluate time-dependent alterations in petrophysical and geomechanical rock properties under CO₂-brine exposure.In the first phase, six ML algorithms Decision Tree, Random Forest, Extra Trees, XGBoost, LightGBM, and K-Nearest Neighbor were applied to predict key petrophysical parameters …


Data-Driven Evalutation And Optimization Of Fishbone Well Configurations For Geothermal Energy Recovery In The Red River Formation, Cedar Creek Anticline, Candace Proksch Dec 2025

Data-Driven Evalutation And Optimization Of Fishbone Well Configurations For Geothermal Energy Recovery In The Red River Formation, Cedar Creek Anticline, Candace Proksch

Theses and Dissertations

This thesis evaluates the geothermal potential of the Red River C interval at the Cedar Creek Anticline and develops a workflow for screening fishbone multilateral designs in a heterogeneous carbonate reservoir. Regional heat-flow and depth maps delineated Cedar Creek as a thermally favorable site and the lower dolomite as the primary reservoir target, supporting construction of a 3D Petrel model that captured the five-member C-interval architecture, petrophysical properties, and temperature field. A multi-stage Particle Swarm Optimization and fast-marching framework used this model to generate and rank fishbone injector–producer configurations, and a line-source approximation combined with a fixed-efficiency Organic Rankine Cycle …


A Space Propulsion Concept Based On Inertial Confinement: Exploring Nuclear Fusion Utilizing Polywell Geometry, Preeti Nair Dec 2025

A Space Propulsion Concept Based On Inertial Confinement: Exploring Nuclear Fusion Utilizing Polywell Geometry, Preeti Nair

Theses and Dissertations

Nuclear fusion propulsion represents a promising solution for future interplanetarymissions due to its high energy density and potential for continuous power generation. However, existing fusion propulsion systems face significant limitations, particularly in achieving stable plasma confinement. The Polywell concept, introduced by physicist Robert Bussard in 1985, offers advantages through its compact, polyhedral geometry that is wellsuited for spacecraft applications where mass and volume constraints are critical. Despite these advantages, Polywell designs have encountered stability challenges in maintaining the electric potential well over time. Plasma instabilities induced by magnetic fields disrupt containment and reduce fusion efficiency, limiting overall performance and scalability …


Exploratory Study Of Relationships Between Law Students' Well-Being, Academic Success, And Perceptions Of Passing The Bar Exam And Admission, Pamela Shea Dec 2025

Exploratory Study Of Relationships Between Law Students' Well-Being, Academic Success, And Perceptions Of Passing The Bar Exam And Admission, Pamela Shea

Theses and Dissertations

This study explores the experiences of law students that impact their perception of being prepared for the Bar Exam and Bar admission. Analyzing the stressors law students face during law school reveals the essential need to incorporate the eight dimensions of well-being into curricular, co-curricular, and extra-curricular activities for students to flourish as they prepare for post-graduation success. Using the data from the 2021 Survey of Law Student Well-Being, which surveyed 5,865 law students from thirty-nine ABA-accredited law schools, a three-factor model was created to group students’ concerns into academic and health concerns, social and environmental concerns, and well-being behavioral …


The Impacts Of Hydrometeor Centrifuging On Numerical Simulations Of Supercells And Tornado-Like Vortices, Ronald Stenz Dec 2025

The Impacts Of Hydrometeor Centrifuging On Numerical Simulations Of Supercells And Tornado-Like Vortices, Ronald Stenz

Theses and Dissertations

Supercell simulations capable of resolving a tornado-like vortex (TLV) have typically ignored hydrometeor centrifuging, resulting in the unrealistic buildup of precipitation in the center of TLVs. To improve the realism of numerical simulations of supercells and their resulting TLVs, an algorithm to parameterize bulk hydrometeor centrifuging was incorporated into an idealized cloud model. Simple idealized vortex simulations and simulations of supercells producing TLVs were analyzed to determine the impacts of hydrometeor centrifuging on numerically simulated supercells and TLVs. The inclusion of hydrometeor centrifuging does not appear to directly impact the intensity and duration of supercell spawned TLVs. Although precipitation minima …


Experimental And Computational Insights Into Reservoir Rock Mechanics And Petrophysical Properties, Prasad Pothana Dec 2025

Experimental And Computational Insights Into Reservoir Rock Mechanics And Petrophysical Properties, Prasad Pothana

Theses and Dissertations

This dissertation investigates the influence of stress, mineralogy, and microstructure on the elastic and transport properties of reservoir rocks. A multi-scale framework integrating laboratory measurements, petrophysical inversion, and discrete-element simulations is developed to quantify the stress-dependent behavior of heterogeneous sedimentary formations relevant to hydrocarbon production and CO2 sequestration.

Core-scale experiments quantify velocity–effective stress and permeability–effective stress relationships in tight siliciclastic and mixed lithologies. Results demonstrate that pore-throat collapse and microcrack closure under confining stress cause systematic reductions in permeability and acoustic velocities. The derived empirical functions provide predictive capability for estimating in-situ stress effects on reservoir performance and time-lapse seismic …


Microbial Communities And Host Plants Of Megachilidae In The Greater Grand Forks Area (Ggfa), Sara Margit Wallace Dec 2025

Microbial Communities And Host Plants Of Megachilidae In The Greater Grand Forks Area (Ggfa), Sara Margit Wallace

Theses and Dissertations

Although Megachilidae are important pollinators in the United States, there is still much to learn about the health and functionality of these bees. Megachilids are threatened by competition from non-native pollinators and other environmental factors. The species distribution and composition of the gut microbiome in megachilid bees are not well known for the Greater Grand Forks Area (GGFA). My research seeks to answer the questions: what megachilid species are in the GGFA, where are they, and what symbionts are in their gut microbiomes? I collected and identified solitary bee specimens from North Dakota and Minnesota, dissected their gut contents, and …


Examining The Utility Of Haptic Feedback To Improve Pilot Situational Awareness & Performance: A Psychophysiological Approach, Jessica Van Bree Dec 2025

Examining The Utility Of Haptic Feedback To Improve Pilot Situational Awareness & Performance: A Psychophysiological Approach, Jessica Van Bree

Theses and Dissertations

Pilot situational awareness (SA) has been deemed to be a critical component of flight efficacy, efficiency, and overall mission success. Studies have shown that several incidents and accidents have been the result of level-one SA errors, meaning that members of the flight crew have failed to accurately perceive the elements in their environments. As such, several strategies have been investigated to improve pilot SA. One potential avenue of research is the addition of haptics in to the flight deck. In some studies, the implementation of haptics have shown to improve piloting tasks, pilot safety, and aircraft control. The current study …


Case Presentation: 40 Year-Old Female With Chronic Neck And Low Back Pain, Chloe Nilles Dec 2025

Case Presentation: 40 Year-Old Female With Chronic Neck And Low Back Pain, Chloe Nilles

Aurora GME

No abstract provided.


Case Presentation: Unilateral Neuroforaminal Widening/Expansion On Cervical Radiograph, Mya J. Reese Dec 2025

Case Presentation: Unilateral Neuroforaminal Widening/Expansion On Cervical Radiograph, Mya J. Reese

Aurora GME

No abstract provided.


Cefadroxil-Induced Drug Reaction With Eosinophilia And Systemic Symptoms (Dress) Syndrome After Double Mastectomy For Ductal Carcinoma In Situ: A Case Report, Iyawnna Hazzard, Alexandra Hong, Darius J. Shahbazi, Shahin Shahbazi Dec 2025

Cefadroxil-Induced Drug Reaction With Eosinophilia And Systemic Symptoms (Dress) Syndrome After Double Mastectomy For Ductal Carcinoma In Situ: A Case Report, Iyawnna Hazzard, Alexandra Hong, Darius J. Shahbazi, Shahin Shahbazi

Student Publications

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a delayed hypersensitivity reaction to medications, characterized by a prodrome of malaise and fever, followed by skin and hematologic manifestations and end-organ damage. Typical causal agents of DRESS syndrome include allopurinol, aromatic anticonvulsants, and antibiotics. However, fewer than 3% of cases suggest cephalosporin-induced DRESS syndrome.

A 43-year-old female developed a diffuse, erythematous, pruritic rash encompassing her whole body after starting prophylactic cefadroxil therapy before a double mastectomy for ductal carcinoma in situ. Her rash continued to worsen despite discontinuation of cefadroxil and developed a fever, myalgias, and generalized weakness. In …


Antipsychotic Misuse: A Silent But Growing Public Health Hazard, Sumeet Bhardwaj, Karisma Pathak, Myra Mclenon, Steven Spector, Kevin Tu Dec 2025

Antipsychotic Misuse: A Silent But Growing Public Health Hazard, Sumeet Bhardwaj, Karisma Pathak, Myra Mclenon, Steven Spector, Kevin Tu

Student Publications

Antipsychotic drugs are essential in the management of schizophrenia, bipolar disorder, and other psychiatric illnesses, but their use is closely linked to cardiometabolic side effects. Cardiometabolic side effects include weight gain, dyslipidemia, glucose intolerance, and increased cardiovascular morbidity and mortality. Mechanisms of cardiometabolic side effects involve disruption of the central nervous system’s ability to regulate appetite, peripheral metabolic effects, which are changes in metabolism outside the CNS, and receptor-level interactions, with second-generation antipsychotics generally posing a greater risk than first-generation agents. This review addresses current evidence on the cardiometabolic consequences of antipsychotic therapy, increasing inappropriate off-label use of antipsychotic drugs, …