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Error Reduction Methodology And Data Simulation For Interval Data, Ranik Christopher Jelinek Dec 2025

Error Reduction Methodology And Data Simulation For Interval Data, Ranik Christopher Jelinek

Undergraduate Honors Capstone Projects

Chronic kidney disease (CKD) is a progressive condition affecting hundreds of millions of individuals worldwide. However, clinical datasets often record continuous laboratory measurements as categorical intervals rather than precise numerical values. This interval-censored structure presents methodological challenges for standard regression-based classifiers. This study compares three strategies for handling interval-valued predictors prior to fitting a logistic LASSO model: (1) midpoint imputation, which replaces each interval with its arithmetic center; (2) ordinal encoding, which maps intervals to integer ranks; and (3) a Monte Carlo simulation approach, which repeatedly samples uniformly from each observed interval and averages predictions across replications. Using a 10-fold …


Role Of Competition In Avoiding Social Collapse, Gabriel M. Tonks Dec 2025

Role Of Competition In Avoiding Social Collapse, Gabriel M. Tonks

All Graduate Reports and Creative Projects, Fall 2023 to Present

Historical examples suggest that isolated, resource-scarce societies are prone to increased hostility and social disasters. The research in this report explores the role of intrasocietal competition in avoiding resource collapse. Two resource-consumer models are proposed with competition which depends on the level of available resources. One of these models is selected for in-depth analysis, and the region in the parameter space where saddle-node bifurcations emerge is computed numerically. The effects of environmental noise on resource growth are simulated, showing that the increased noise usually has negative long-term effects which might be mitigated via increased consumer competition.


Modeling And Analysis Of Electric Signal In Neurons, Kevin J. Roberts Dec 2025

Modeling And Analysis Of Electric Signal In Neurons, Kevin J. Roberts

All Graduate Reports and Creative Projects, Fall 2023 to Present

Neurons in humans and other species transmit information by sending electric signals via axons. This process relies on the generation and propagation of action potentials—rapid changes in the membrane potential of the axon. Understanding the mechanisms of action potentials, including how they are generated and influenced by the axon geometry and material parameters, is crucial for gaining insight into neurological diseases such as Alzheimer’s and Multiple Sclerosis (diseases highly correlated to demyelination). In this work, we review and summarize mathematical models for signal transmission–including the classical Hodgkin-Huxley model, the Single Cable (SC) model, and the Double Cable (DC) model. We …


White Horse Village: A Northern Utah Ufo Narrative, Melissa Petersen Dec 2025

White Horse Village: A Northern Utah Ufo Narrative, Melissa Petersen

All Graduate Reports and Creative Projects, Fall 2023 to Present

In the early 1960's a group of UFO believers, called Christ Brotherhood Inc., established themselves in Smithfield Canyon, UT and called their commune White Horse Village. A main house was built where the leader of the group lived and two or three smaller cabins were erected for the believers. Without running water they used an outhouse among them and built a small church where they would meet for lectures. Their beliefs centered around the popular movement of New Age spirituality of the time, which included scientific explanations for Christian beliefs including a belief in benevolent aliens as modern angels. Their …


The Depositional Environment Of The Triassic Cow Branch Formation, Dan River Basin Of Virginia And North Carolina Through Petrographic Study And Geochemical Analysis, And In Relation To Taphonomic Processes And Vertebrate Morphology, Gina M. Workman Dec 2025

The Depositional Environment Of The Triassic Cow Branch Formation, Dan River Basin Of Virginia And North Carolina Through Petrographic Study And Geochemical Analysis, And In Relation To Taphonomic Processes And Vertebrate Morphology, Gina M. Workman

All Graduate Reports and Creative Projects, Fall 2023 to Present

The Upper Triassic Cow Branch Formation of the Dan River Basin, located in southern Virginia and northern North Carolina, has long captivated generations of geoscientists. Since the 1970s, researchers have sought to unravel the mystery surrounding the depositional environment of this ancient lake system. This world-class lagerstätte hosts a diverse assemblage of fossil fauna and flora, with a notable preservation bias toward fossil vertebrates, most prominently the archosauromorph, Tanytrachelos ahynis. The geology of the Cow Branch strata continues to evoke a persistent question: Are these sediments representative of a shallow or deep lake?

I undertook a petrographic and geochemical study …


Thermal And Non-Thermal Mass Transport Effects In Plasmon-Assisted Electrochemistry., Md Al Amin Dec 2025

Thermal And Non-Thermal Mass Transport Effects In Plasmon-Assisted Electrochemistry., Md Al Amin

Electronic Theses and Dissertations

Plasmon-assisted electrochemistry has received attention due to its effects of hot charge carriers, photothermal heating, and enhanced electromagnetic field impact on electrochemical transformation. These effects have contributed to lowering the onset potential and increasing the reaction kinetics. Numerous studies have been employed to differentiate the effect of photothermal heating from hot charge carriers on the electrochemical reaction. Most of these studies have been employed to measure and quantify the photothermal heating effects at equilibrium temperature; however, localized heating from the incident light does not result in homogeneous heating across the electrochemical cell. Many studies investigating the photothermal heating effect in …


A Persistent Homology Framework For Scrna-Seq: Assessing Clustering Robustness And Quantifying Preprocessing And Integration Effects On Topological Features., Jonah Daneshmand Dec 2025

A Persistent Homology Framework For Scrna-Seq: Assessing Clustering Robustness And Quantifying Preprocessing And Integration Effects On Topological Features., Jonah Daneshmand

Electronic Theses and Dissertations

As single-cell RNA sequencing (scRNA-seq) data expands, robust methods for integrating diverse datasets are critical. This dissertation applies Persistent Homology (PH), a technique from Topological Data Analysis (TDA), to a collection of scRNA-seq datasets spanning eight tissue types to quantify how data integration affects topological features and biological interpretability. We assessed global topological structure using Betti curves, Euler characteristics, and persistence landscapes across raw, normalized, and integrated data representations. Our analysis revealed a performance inversion: while conventional methods excelled on unintegrated data, high-granularity topological methods, particularly those sensitive to global data structure, became superior after integration. This suggests a synergy …


Increasing Histidyl Dipeptides In Skeletal Muscle Preserves Muscle Mass And Function In Heart Failure., Mamata Hiraman Chaudhari Dec 2025

Increasing Histidyl Dipeptides In Skeletal Muscle Preserves Muscle Mass And Function In Heart Failure., Mamata Hiraman Chaudhari

Electronic Theses and Dissertations

Introduction: Heart failure is a systemic disease associated with multiple comorbidities, such as skeletal muscle wasting and cardiopulmonary disease. Muscle wasting in heart failure patients is a severe comorbidity associated with decreased exercise capacity and poor quality of life. Previous reports show that oxidative stress is increased in the skeletal muscle of heart failure patients, which can directly lead to muscle wasting. However, antioxidant intervention in these patients was unable to improve cardiac function and consequently had no effect on muscle wasting. Although oxidative stress is the primary driver of skeletal muscle atrophy, no attempt has been made to examine …


Orientation Or Disorientation? A Critical Content Analysis Of Refugee Cultural Orientation Curriculum., Amanda Jean Lacey Dec 2025

Orientation Or Disorientation? A Critical Content Analysis Of Refugee Cultural Orientation Curriculum., Amanda Jean Lacey

Electronic Theses and Dissertations

Cultural Orientation (CO) is a free, legally mandated, multi-session program intended to provide refugee newcomers ages 18-65 with the knowledge, skills, and attitudes needed to integrate and achieve self-sufficiency in the United States. Despite occurring at a critical time in the resettlement process, there has been almost zero scholarship analyzing the content or efficacy of domestic CO curriculum. This dissertation addresses that gap by performing a Critical Content Analysis (CCA) on The Road Ahead (TRA), the de facto official CO curriculum promoted through the Cultural Orientation Resource Exchange (CORE). Framed by a postcolonial perspective and informed by the …


An Exploration Of Factors Associated With Sport Fan's' Choice Of Ticketing Platforms., Jacob Owsley Dec 2025

An Exploration Of Factors Associated With Sport Fan's' Choice Of Ticketing Platforms., Jacob Owsley

Electronic Theses and Dissertations

This research study examined key experiential and demographic factors associated with sport consumers’ choice of online ticketing platforms. The research applied the technology acceptance model (TAM) to examine how trust, official sponsorship, user interface design, and price consciousness are associated with consumers’ choice between different online ticketing platforms.. Data were collected from 312 adult sport consumers in the United States through an online survey distributed across six Reddit communities focused on ticketing or research activities. Participants included individuals who bought tickets to professional sports events and attended these events during the last 12 months. The expert review process and two …


The Autonomic And Arrhythmogenic Effects Of Gestational E-Cigarette Exposure., Brittany Rachelle Reynolds Dec 2025

The Autonomic And Arrhythmogenic Effects Of Gestational E-Cigarette Exposure., Brittany Rachelle Reynolds

Electronic Theses and Dissertations

Introduction. E-cigarettes (e-cigs) have been shown to be pro-arrhythmic in both human and male rodent studies; however, little is known about how e-cig use impacts patients with a predisposed heightened risk for arrhythmias, including pregnant women. Both pregnancy and e-cig use have independently been shown to increase heart rate, diminish heart rate variability, and increase ventricular premature beats, which is suspected to be due to sympathetic dominance. Importantly, β-blockers have been shown to reduce sympathetic activity, reduce heart rate, increase HRV, and reduce arrhythmias. Thus, the use of β-blockers may help prevent adverse health effects driven by sympathetic dominance from …


What Will It Take To Keep You? A Phenomenological Investigation Of Teacher Career Decisions In Title I Elementary Schools., Tonya Nicole Holt Dec 2025

What Will It Take To Keep You? A Phenomenological Investigation Of Teacher Career Decisions In Title I Elementary Schools., Tonya Nicole Holt

Electronic Theses and Dissertations

This qualitative phenomenological study explored the factors influencing teachers’ decisions to remain in or leave Title I elementary schools in Kentucky. Grounded in Herzberg’s Motivation–Hygiene Theory, the study examined the interplay of intrinsic motivators and extrinsic conditions that shape teacher satisfaction, commitment, and attrition. Twelve current Title I teachers participated in semi-structured interviews designed to capture their lived experiences and perceptions of work in high poverty contexts. Analysis revealed a balance of pull factors—such as purpose, relationships, and supportive leadership—and push factors—including workload, resource limitations, and inadequate administrative support. Leadership quality emerged as the central variable mediating these forces. Teachers …


Thermal Heterogeneity And Lithium Plating During Fast Charging Of Lithium-Ion Battery., Ayodeji Avis Adeniran Dec 2025

Thermal Heterogeneity And Lithium Plating During Fast Charging Of Lithium-Ion Battery., Ayodeji Avis Adeniran

Electronic Theses and Dissertations

Presently, widespread adoption of electric vehicles (EVs) is hindered by challenges associated with XFC, including heat generation, lithium plating, and accelerated battery degradation. This dissertation addresses these barriers through two coordinated themes—lithium plating and thermal management—spanning four manuscripts that integrate operando diagnostics, physics-based simulation, and module-level design optimization. The first theme seeks a fundamental investigation into the dynamic interplay between temperature heterogeneity and lithium plating during fast charging, a phenomenon that poses significant limitations on the performance of graphite-based anodes. Firstly, a custom operando cell with a sapphire window was designed to enable synchronized MWIR thermography and optical imaging of …


Acceptance And Commitment Therapy As A Transdiagnostic Approach To Improve Quality Of Life Among Adults Living With A Physical Chronic Health Condition, Marissa L. Donahue Dec 2025

Acceptance And Commitment Therapy As A Transdiagnostic Approach To Improve Quality Of Life Among Adults Living With A Physical Chronic Health Condition, Marissa L. Donahue

All Graduate Theses and Dissertations, Fall 2023 to Present

The research contained in this dissertation presents rationale and empirical support for the application of acceptance and commitment therapy (ACT) as a transdiagnostic approach in improving quality of life for adults living with chronic health conditions (CHCs). The first study consists of a systematic review that aims to examine (1) the current state of evidence of ACT for adults living with a CHC, (2) how outcomes are being characterized within this population, (3) the methodological quality of the included trials, as well as (4) summarizing the health conditions in which ACT has been evaluated for. The second study examines the …


The Equity Implications Of Pecuniary Externalities On An Electric Grid, Charles Sims, Gasser G. Ali, J Scott Holladay, Tim Roberson, Chien-Fei Chen, Islam H. El-Haddad Dec 2025

The Equity Implications Of Pecuniary Externalities On An Electric Grid, Charles Sims, Gasser G. Ali, J Scott Holladay, Tim Roberson, Chien-Fei Chen, Islam H. El-Haddad

Civil Engineering Faculty Publications

The adoption of rooftop photovoltaic (PV) systems can create upward pressure on retail electricity rates as utilities are forced to spread their fixed costs of generation and transmission across a smaller customer base. Since high-income households are more likely to purchase PV systems, low-income households may be disproportionately impacted by these rate increases. Using a novel combination of agent-based computational economic modeling and a choice experiment of rooftop solar adoption, we show how this pecuniary externality between low- and high-income customers increases low-income electricity bills by 10% in an area with some of the highest poverty rates in the United …


Summary Of Pine Valley Area Groundwater Studies, Melissa Stamp, Bethany Neilson, Anna Mcentire, Burdette Barker, Lisa Welsh, Joanna Endter-Wada, Brian Steed Dec 2025

Summary Of Pine Valley Area Groundwater Studies, Melissa Stamp, Bethany Neilson, Anna Mcentire, Burdette Barker, Lisa Welsh, Joanna Endter-Wada, Brian Steed

Reports

The Utah Division of Water Resources contracted with Utah State University to document key scientific and policy information related to the current water conflict between Iron and Beaver Counties over the development of the Pine Valley Water Supply Project (PVWSP). The proposed PVWSP would pump groundwater from Pine Valley in Beaver County and pipe it southeast to the Cedar City region of Iron County served by the Central Iron County Water Conservancy District (CICWCD). Numerous concerns about the project have been raised by Beaver County and other interested parties. A number of these concerns are related to different understandings or …


Impact Of Thermodynamic Factors And Intrinsic Properties On Crystallization Behavior And Physical Properties Of Edible Fats, Nabila Anjum Dec 2025

Impact Of Thermodynamic Factors And Intrinsic Properties On Crystallization Behavior And Physical Properties Of Edible Fats, Nabila Anjum

All Graduate Theses and Dissertations, Fall 2023 to Present

Crystallization behavior of three edible fats: interesterified soybean oil (IESBO), interesterified palm olein (IEPO), and fully hydrogenated palm kernel oil (FHPKO) were explored to understand how this process is affected by different factors. The study focused on how the chemical composition of these fats affects their behavior like how much time they require to be crystallized at a certain temperature. By using different scientific methods, how quickly each fat began to crystallize and how much energy it took to start the process was measured. Among the methods used, Gompertz equation, a mathematical model, gave the most consistent and reliable results …


Spatial Strategies For Restoring Native Biodiversity And Connectivity In Managed Landscapes Of The Upper Clutha Basin, New Zealand, Jessica Zuban Dec 2025

Spatial Strategies For Restoring Native Biodiversity And Connectivity In Managed Landscapes Of The Upper Clutha Basin, New Zealand, Jessica Zuban

All Graduate Theses and Dissertations, Fall 2023 to Present

Across New Zealand and around the world, biodiversity is declining due to the widespread loss and fragmentation of native habitat. This is especially true in agricultural landscapes, where native habitats have been replaced by intensive land use. This research focuses on the Upper Clutha Basin in Central Otago, New Zealand that has been significantly altered over time by farming, development, and other human activities. As a result, only a small amount of native vegetation remains, and the region is well below the critical threshold needed to support healthy ecological systems.

This study investigates how native vegetation can be strategically restored …


The Sexual Objectification Experiences Of Amab Non-Binary People, Lee Rosemary Pradell Dec 2025

The Sexual Objectification Experiences Of Amab Non-Binary People, Lee Rosemary Pradell

All Graduate Theses and Dissertations, Fall 2023 to Present

The current study combines two narrative-based methods to understand how AMAB non-binary people experience sexual objectification. Sexual objectification is the process of being treated as an object instead of as a whole person while also being sexualized. Individual people can sexually objectify others (i.e., catcalling, asking “What gender are you really?”, repeatedly asking female people about when they’re giving birth); institutions and systems can also objectify people (i.e., listing sex on driver’s licenses instead of gender; providing binary bathrooms, sports teams, and schooling; labeling female reproductive care “women’s health”).

The current study employed a process chart task that guided participants …


Fast Computation Of The Friction Stir Welding Process With Model Order Reduction, Joshua Kay Dec 2025

Fast Computation Of The Friction Stir Welding Process With Model Order Reduction, Joshua Kay

All Graduate Theses and Dissertations, Fall 2023 to Present

Friction stir welding (FSW) is a manufacturing process used to join materials through intense heat and pressure. To better understand and optimize this FSW process, mathematical models incorporating non-Newtonian Navier-stokes equations for large plastic deformation and heat equation for the heat transfer are used to simulate the FSW process. However, solving these coupled and nonlinear equations with high accuracy requires significant computational power and time. This thesis has applied model order reduction, more precisely the Proper Orthogonal Decomposition (POD) and Discrete Empirical Interpolation Method (DEIM), to efficiently solve the FSW system in low-dimensional space. Slight modifications are made regarding the …


The Impact Of Transmission Thresholds Across Multiple Scales On The Spread Of Chronic Wasting Disease In Wisconsin, Jen Mcclure Dec 2025

The Impact Of Transmission Thresholds Across Multiple Scales On The Spread Of Chronic Wasting Disease In Wisconsin, Jen Mcclure

All Graduate Theses and Dissertations, Fall 2023 to Present

Wildlife diseases can be difficult to control once they are established. This is especially true when they spread through contact with infectious material left in the environment. One such disease is chronic wasting disease (CWD), a fatal illness affecting deer and related species in North America and other regions. CWD is caused by prions, misfolded proteins that can remain infectious for years after shedding by infected hosts.

Recent research shows that CWD infection does not always follow from the gradual accumulation of prions through small contact events. Rather, an individual may need to encounter a certain prion dose all at …


Dynamics, Predictability And Impacts Of Multi-Year La Niña Event, Nahid A. Hasan Dec 2025

Dynamics, Predictability And Impacts Of Multi-Year La Niña Event, Nahid A. Hasan

All Graduate Theses and Dissertations, Fall 2023 to Present

This dissertation investigates the dynamics, predictability, and impacts of multi-year La Niña events. Multi-year La Niña events are referred to as extended periods of unusually cooler tropical Pacific that persist for two or more consecutive winters. These prolonged events can increase the risk of natural hazards such as droughts, floods, and heatwaves in the western US and around the world. Despite their worldwide significance, questions remain about the mechanisms driving their initiation, their predictability, and regional hydroclimate impacts.

The first chapter of the dissertation introduces what scientists currently believe causes them, and how well different types of climate models can …


Examing Fear Conditioning/Extinction And The Role Of The Amygdala In Human Neuroimaging., Olivia Cook Dec 2025

Examing Fear Conditioning/Extinction And The Role Of The Amygdala In Human Neuroimaging., Olivia Cook

Electronic Theses and Dissertations

Fear plays a crucial role in survival but can lead to psychological disorders when dysregulated. Fears can be innate due to evolutionary relevance or learned through associative processes, where predictive accuracy of threat is pivotal. Disruptions in fear neurocircuitry contribute to anxiety disorders, characterized by heightened activation and impaired learning. Fear conditioning and extinction paradigms based on classical Pavlovian conditioning have been used to study mechanisms underlying fear learning. Using this experimental model, fear networks in rodents have been described in detail with clear distinction between conditioning and extinction neural functioning. Yet, there is no consensus on the neurobiological processes …


Nonlinear Phase Space Analysis For Anomaly Detection In Ros 2 Communications: Detecting Man-In-The-Middle Attacks In Simulated Environments, William L. Locklier Dec 2025

Nonlinear Phase Space Analysis For Anomaly Detection In Ros 2 Communications: Detecting Man-In-The-Middle Attacks In Simulated Environments, William L. Locklier

Graduate Theses and Dissertations (2019 - present)

Robot Operating System 2 (ROS 2) marks a significant advancement over its predecessor through the transition from a centralized to a decentralized architecture, integrating the Data Distribution Service (DDS) to support real-time, scalable communications. Despite these improvements, inherent vulnerabilities in the ROS 2 communication stack continue to leave these systems exposed to sophisticated network-based attacks. This study leveraged nonlinear phase space analysis (NLPSA) as an intrusion detection system (IDS) to detect man-in-the-middle (MitM) attack anomalies in ROS 2 traffic. Grounded in Takens’ embedding theorem, NLPSA reconstructs the phase space of communication features and compares the resulting structure against a baseline …


Depth-Averaged Two-Dimensional Hydrodynamic Modeling In Headwater Channel And Floodplain Design., Jesse Dylan Robinson Dec 2025

Depth-Averaged Two-Dimensional Hydrodynamic Modeling In Headwater Channel And Floodplain Design., Jesse Dylan Robinson

Electronic Theses and Dissertations

In the channels and floodplains of inland waterways the hydrodynamic forces of floods destroy property and infrastructure, threaten lives, and damage aquatic habitat. Flood simulations using robust and efficient depth-averaged two-dimensional hydrodynamic models (2D models) can be interpreted to design effective solutions for areas vulnerable to damage. The reliable interpretation of 2D models for use in design is improved here through direct comparison of 2D model output to observed flood events at 6 headwater research sites. Instrumentation was used for model calibration and to define the surface hydrodynamics at sites with confined flows, wide and shallow flows, at vertical steps, …


Experiences Of Research Administrators With Faculty Researchers In Sponsored Project Compliance., Adrienne M. Lindsay Dec 2025

Experiences Of Research Administrators With Faculty Researchers In Sponsored Project Compliance., Adrienne M. Lindsay

Electronic Theses and Dissertations

The purpose of this study was to examine how central office research administrators perceive and describe their professional interactions with faculty researchers, and how those relationships may impact compliance with sponsored project requirements in United States higher education institutions. Cohen et al.’s (1972) organized anarchy theory and Schein’s (2010) organizational culture theory provided a foundational context for understanding research systems within higher education institutions and the social environment in which research administrators navigate potentially contentious roles, both facilitating research and stewarding compliance for the institution and the sponsor. Findings emerged around specific challenges faced by research administrators, which included role …


Risk And Protective Factors For Suicidal Thoughts And Behaviors For Black Adolescent Males With Exposure To Adverse Experiences Post-Covid 19 Pandemic: Findings From The 2023 National Youth Risk Behavior Survey., Amanda Minogue Dec 2025

Risk And Protective Factors For Suicidal Thoughts And Behaviors For Black Adolescent Males With Exposure To Adverse Experiences Post-Covid 19 Pandemic: Findings From The 2023 National Youth Risk Behavior Survey., Amanda Minogue

Electronic Theses and Dissertations

Suicide is the second leading cause of death among adolescents aged 10-24 in the United States. In 2022, 784 Black adolescent males died by suicide. Recent studies have found that traditionally common associations of risk factors of suicidal thoughts and behaviors are not experienced by Black adolescents, challenging how to determine and detect risk. This dissertation reviewed the variables in the national Youth Risk Behavior Survey that closely align with risk and protective factors of suicidal thoughts and behaviors, and the interaction between these and adverse experiences in Black adolescent males. Results of this study found that among the 9 …


The Role Of Fast-Food Consumption, Residential Fast-Food Exposures, And Urinary Essential Trace Heavy Metals In Colorectal Cancer (Crc) Outcomes., Jeevan Adhikari Dec 2025

The Role Of Fast-Food Consumption, Residential Fast-Food Exposures, And Urinary Essential Trace Heavy Metals In Colorectal Cancer (Crc) Outcomes., Jeevan Adhikari

Electronic Theses and Dissertations

Background: Colorectal cancer (CRC) is a public health concern. Within the United States (US), fast-food consumption and environmental exposure to heavy metals have increased. The impact of fast-food consumption frequency from fast-food restaurants, residential fast-food exposures, and urinary essential trace heavy metals in relation to CRC outcomes have not yet been rigorously evaluated in the US. Methods: Within the LEAPS-CRC study, we used geographic information systems (GIS) and logistic regression to study the association of fast-food consumption, residential proximity to a fast-food outlet, and urinary essential trace metals with CRC incidence. Additionally, within Kentucky Cancer Registry (KCR) CRC cases, the …


Genetic Identification Of A Rapidly-Adapting Low-Threshold Mechanoreceptor Innervating Fungiform Papillae., Thomas Alexander Myers Ii Dec 2025

Genetic Identification Of A Rapidly-Adapting Low-Threshold Mechanoreceptor Innervating Fungiform Papillae., Thomas Alexander Myers Ii

Electronic Theses and Dissertations

Mechanosensory innervation of the oral cavity enables us to detect the texture and location of the foods we consume. Our goal was to find a genetic identifier for a mechanoreceptive subtype. Toward this goal, we examined neurons expressing the neurotrophin receptor TrkC, parvalbumin (Pvalb), and the glutamate transporter Vglut3. Because different papilla types contribute to food detection in different ways, we examined the innervation patterns of these neuron subtypes. We found that Pvalb+ and Vglut3+ neurons were fungiform papilla specific, where TrkC innervated both papilla types. We examined the anatomy of the three genetic populations, finding that the Pvalb+ neurons …


Residential Segregation And Breast Cancer In Louisville: Impact Of Race And Contextual Factors On Advanced-Stage Diagnosis, Delayed Treatment, And Disease-Specific Mortality., Toheeb Ajani Mustapha Dec 2025

Residential Segregation And Breast Cancer In Louisville: Impact Of Race And Contextual Factors On Advanced-Stage Diagnosis, Delayed Treatment, And Disease-Specific Mortality., Toheeb Ajani Mustapha

Electronic Theses and Dissertations

Female breast cancer (BC) remains the most commonly diagnosed non-skin cancer and the second leading cause of cancer death among U.S. women. Despite advances in detection and treatment, substantial inequities in BC outcomes persist, driven in part by structural forces such as residential segregation. This dissertation examined the relationship between residential segregation, BC outcomes, and key contextual factors in Louisville, Kentucky. Using data from the Kentucky Cancer Registry, American Community Survey, CDC’s Population-Level Analyses and Community Estimates, and the National Neighborhood Data Archive, the study tested two hypotheses: (1) higher Black/low-income segregation is associated with elevated risks of adverse BC …